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The map label for this gene is hemX

Identifier: 255767646

GI number: 255767646

Start: 2876928

End: 2877758

Strand: Reverse

Name: hemX

Synonym: BSU28160

Alternate gene names: 255767646

Gene position: 2877758-2876928 (Counterclockwise)

Preceding gene: 16079869

Following gene: 16079867

Centisome position: 68.26

GC content: 41.52

Gene sequence:

>831_bases
ATGATTGATACTGCAATGGCAAGACTTAATGAGGGGACAATCGTCATTTACGCGTTAAGTGTACTCTTTTATTTTATAGA
TTTTCTTCAACACAACCGGAAGGCTGGAAAAATGGCCTTCTGGTTGCTTTCTATTGTCTGGACTCTGCAAACCGTGTATT
TGGCCTATTTTATGTGGGTGACGGGGCGGTTTCCGGTATTAAATGTGACAGAGGCACTTTATTTTTATGCCTGGGTGCTT
GTCACGCTGTCACTTGTACTGACAAAGCTTTTACGTGTTGACTTTATCGTGTTTTTTACAAATGTTATAGGATTTTCTAT
GATCGCCATTCACACATTTTCACCGACAGAGCAGCAGTCAGCTGCTTTTTCCGGGCAGCTTGTATCCGAGCTTTTGGTGA
TTCATATTACAATGGCGATTCTTTCATACGGCGCTTTTTCCCTTTCTTTCGTTTTTTCTGTGCTATATATGTTTCAATAT
CATCTGCTGAAAAAGAAAAAGTGGGGAAAATGGCTGTTGAGAATAGAAGATTTATCTAAGCTTGATTATATGGCGTATGT
TTTAAATGTCATTGGGGTTCCGATGCTGCTGCTGAGTTTGATTCTCGGCGTCATTTGGGCGTATGTCTCACTAGAAACGC
TGTATTGGTTTGACGCCAAAGTGCTTGGTTCGTTTGTCGTCCTGCTGCTGTACAGCTATTATCTTTATATCAGGCTGATT
AAGGAGCTGCAAGGAAAGGTCGCTGCACTGTGGAATACGGCTTGTTTTCTGGTGCTGATGATCAATTATTTCCTGCTTGG
AAGCCTGTCGCAATTCCATTGGTTCAGTTAA

Upstream 100 bases:

>100_bases
CAAATGATGAAAACCGTTGAAAGCAGCCAGAAGGTCCACTCTTTTAAGAAGGCTGAATCAAAAGCGGGCTTTAGCCCACT
TGTAAGTGAGTGAAAGCTGA

Downstream 100 bases:

>100_bases
ACGATGTCCCAAGCAGATTCGGGAGGAAAGAAATGATGAGAACGATTAAAGTAGGTTCCAGACGGAGCAAACTCGCTATG
ACTCAAACAAAATGGGTTAT

Product: negative effector of the concentration of glutamyl-tRNA reductase HemA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MIDTAMARLNEGTIVIYALSVLFYFIDFLQHNRKAGKMAFWLLSIVWTLQTVYLAYFMWVTGRFPVLNVTEALYFYAWVL
VTLSLVLTKLLRVDFIVFFTNVIGFSMIAIHTFSPTEQQSAAFSGQLVSELLVIHITMAILSYGAFSLSFVFSVLYMFQY
HLLKKKKWGKWLLRIEDLSKLDYMAYVLNVIGVPMLLLSLILGVIWAYVSLETLYWFDAKVLGSFVVLLLYSYYLYIRLI
KELQGKVAALWNTACFLVLMINYFLLGSLSQFHWFS

Sequences:

>Translated_276_residues
MIDTAMARLNEGTIVIYALSVLFYFIDFLQHNRKAGKMAFWLLSIVWTLQTVYLAYFMWVTGRFPVLNVTEALYFYAWVL
VTLSLVLTKLLRVDFIVFFTNVIGFSMIAIHTFSPTEQQSAAFSGQLVSELLVIHITMAILSYGAFSLSFVFSVLYMFQY
HLLKKKKWGKWLLRIEDLSKLDYMAYVLNVIGVPMLLLSLILGVIWAYVSLETLYWFDAKVLGSFVVLLLYSYYLYIRLI
KELQGKVAALWNTACFLVLMINYFLLGSLSQFHWFS
>Mature_276_residues
MIDTAMARLNEGTIVIYALSVLFYFIDFLQHNRKAGKMAFWLLSIVWTLQTVYLAYFMWVTGRFPVLNVTEALYFYAWVL
VTLSLVLTKLLRVDFIVFFTNVIGFSMIAIHTFSPTEQQSAAFSGQLVSELLVIHITMAILSYGAFSLSFVFSVLYMFQY
HLLKKKKWGKWLLRIEDLSKLDYMAYVLNVIGVPMLLLSLILGVIWAYVSLETLYWFDAKVLGSFVVLLLYSYYLYIRLI
KELQGKVAALWNTACFLVLMINYFLLGSLSQFHWFS

Specific function: Required for hemL synthesis

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae U1620K

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HEMX_BACSU (P16645)

Other databases:

- EMBL:   M57676
- EMBL:   Z75208
- EMBL:   AL009126
- PIR:   B35252
- RefSeq:   NP_390694.2
- EnsemblBacteria:   EBBACT00000002956
- GeneID:   937489
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU28160
- NMPDR:   fig|224308.1.peg.2819
- GenoList:   BSU28160
- GeneTree:   EBGT00050000002786
- HOGENOM:   HBG314050
- ProtClustDB:   CLSK2523448
- BioCyc:   BSUB:BSU28160-MONOMER
- InterPro:   IPR002541

Pfam domain/function: PF01578 Cytochrom_C_asm

EC number: NA

Molecular weight: Translated: 32052; Mature: 32052

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x117495f8)-; HASH(0x10ee60a4)-; HASH(0x11302868)-; HASH(0xff03014)-; HASH(0x1021a934)-; HASH(0xf733af0)-; HASH(0x115a38a8)-; HASH(0x113a9d30)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2110138; 8969504; 9384377