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The map label for this gene is yrbD

Identifier: 255767637

GI number: 255767637

Start: 2841611

End: 2843065

Strand: Direct

Name: yrbD

Synonym: BSU27810

Alternate gene names: 255767637

Gene position: 2841611-2843065 (Clockwise)

Preceding gene: 255767636

Following gene: 16079840

Centisome position: 67.41

GC content: 47.01

Gene sequence:

>1455_bases
ATGGCAGATTTTGTTGCTAGTTTGAATGCGGTCTTATGGAGTACGCCCGTCATTTATATTTTATTGGGAATTGGATTCGC
CTTTTCAATTATGACCCGTTTTTTACAAGTCCGACATTTAAAAGAAATGATTGTTCAGATGTTCAAAGGCAAGAGCTCTG
AAGCCGGCGTTTCATCTTTCCAAGCGTTATCGATTGCGCTGTCCGGCCGTGTGGGCACAGGAAACATCGCGGGAGTGGCG
ACAGCAATTGCATTCGGCGGACCCGGTGCAGTGTTCTGGATGTGGGCGATTGCCTTTATCGGGGCGGCGAGTGCCTTTGT
AGAATCAACGCTTGCTCAAATTTACAAAGTGAAACAAGACGGTCAATATCGGGGCGGCCCTGCTTATTATATAGAAAAAG
GCTTAGGCATTAAGTGGTTTGCCGTCTTATTTGCCGCTGCTGCCCTTATTGCAATGGCCTTTCTAATGCCGGGCGTACAG
TCCAACTCCATTGCGGCTGGGATCCAAAATGCATTCGGCATCTCTCCTTTCGTCACAGGGTGCGGTCTGGTTTTATTATT
AGGGTTCATTATTTTTGGCGGCGTCAAACGAATTGCCAATGCGGCGCAAATGATTGTTCCATTTATGGCCATTGGATATA
TCCTGCTGTCTTTGATTATTATTGTCATGAATGTGTCTGAATTGCCTGCTGTGATCTCATTAATATTCAAAAGCGCCTTC
GCATTGGATTCCGCTTTTGGCGGCTTGATCGGTATGGCGATTTCCTGGGGCGTTAAACGTGGCATTTACTCAAACGAAGC
CGGCCAGGGAACAGGCCCGCATCCGGCAGCTGCTGCAGAGGTTTCTCATCCGGTCAAGCAGGGACTGGTTCAGGCATTTT
CTGTTTATATTGACACCTTGTTTGTATGTTCCGCTACAGCTTTCATGATCTTGTTTACCGGCATGTACAATACCCAGGCT
GCAGATGGTTCCTTTATCGTTCACCAGCTTAAAGGCGTAGAAGCAGGACCTGGTTTCACACAAGCGGCAATTGACAGTGT
TCTTCCCGGATTCGGTGCAGGCTTTGTTGCCATCGCTTTATTCTTCTTCGCTTTTACAACAATTATGGCGTATTACTACA
TCGCAGAAACAAATATCGCCTATTTAGCACGAGGCAGAGAAAGCAAATGGGCGATGCTTGGCTTAAAACTGATTATTTTA
GCCGCCACGTTCTATGGTACTGTGAAAACAGCTTCACTTGCTTGGGCATTAGGGGATGCAGGGCTTGGCATTATGGTATG
GCTGAACGTCATTGCCATTGTGCTGCTTGCCAAGCCGGCGCTCCTTGCTTTAAAGGATTATGAGCGCCAAAAGAAGCAGG
GCTTAGACCCGATCTTTGATCCAAAAGCGCTGGGTATCAAAAACGCTGATTTCTGGGAGAAAGAATACACTCATGAAAGT
GAACGTGTCTCCTGA

Upstream 100 bases:

>100_bases
TACAGGTCATATAATGTGACAAATCGATTGTAGAAATAGTTCGATTAGACCAAAATCCTTTTTATACATGTATTCGAATT
TGAAGTGAGGGGGAAGCTTG

Downstream 100 bases:

>100_bases
ACATACTAAAACCGGCCCGATATGACCTCGTGCCGGTTTTTTATGAACGATAGTTTGTATACACTTCTTGAACATCATCG
TCATCTTCAAGGACGTCTAT

Product: sodium/proton-dependent alanine transporter

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MADFVASLNAVLWSTPVIYILLGIGFAFSIMTRFLQVRHLKEMIVQMFKGKSSEAGVSSFQALSIALSGRVGTGNIAGVA
TAIAFGGPGAVFWMWAIAFIGAASAFVESTLAQIYKVKQDGQYRGGPAYYIEKGLGIKWFAVLFAAAALIAMAFLMPGVQ
SNSIAAGIQNAFGISPFVTGCGLVLLLGFIIFGGVKRIANAAQMIVPFMAIGYILLSLIIIVMNVSELPAVISLIFKSAF
ALDSAFGGLIGMAISWGVKRGIYSNEAGQGTGPHPAAAAEVSHPVKQGLVQAFSVYIDTLFVCSATAFMILFTGMYNTQA
ADGSFIVHQLKGVEAGPGFTQAAIDSVLPGFGAGFVAIALFFFAFTTIMAYYYIAETNIAYLARGRESKWAMLGLKLIIL
AATFYGTVKTASLAWALGDAGLGIMVWLNVIAIVLLAKPALLALKDYERQKKQGLDPIFDPKALGIKNADFWEKEYTHES
ERVS

Sequences:

>Translated_484_residues
MADFVASLNAVLWSTPVIYILLGIGFAFSIMTRFLQVRHLKEMIVQMFKGKSSEAGVSSFQALSIALSGRVGTGNIAGVA
TAIAFGGPGAVFWMWAIAFIGAASAFVESTLAQIYKVKQDGQYRGGPAYYIEKGLGIKWFAVLFAAAALIAMAFLMPGVQ
SNSIAAGIQNAFGISPFVTGCGLVLLLGFIIFGGVKRIANAAQMIVPFMAIGYILLSLIIIVMNVSELPAVISLIFKSAF
ALDSAFGGLIGMAISWGVKRGIYSNEAGQGTGPHPAAAAEVSHPVKQGLVQAFSVYIDTLFVCSATAFMILFTGMYNTQA
ADGSFIVHQLKGVEAGPGFTQAAIDSVLPGFGAGFVAIALFFFAFTTIMAYYYIAETNIAYLARGRESKWAMLGLKLIIL
AATFYGTVKTASLAWALGDAGLGIMVWLNVIAIVLLAKPALLALKDYERQKKQGLDPIFDPKALGIKNADFWEKEYTHES
ERVS
>Mature_483_residues
ADFVASLNAVLWSTPVIYILLGIGFAFSIMTRFLQVRHLKEMIVQMFKGKSSEAGVSSFQALSIALSGRVGTGNIAGVAT
AIAFGGPGAVFWMWAIAFIGAASAFVESTLAQIYKVKQDGQYRGGPAYYIEKGLGIKWFAVLFAAAALIAMAFLMPGVQS
NSIAAGIQNAFGISPFVTGCGLVLLLGFIIFGGVKRIANAAQMIVPFMAIGYILLSLIIIVMNVSELPAVISLIFKSAFA
LDSAFGGLIGMAISWGVKRGIYSNEAGQGTGPHPAAAAEVSHPVKQGLVQAFSVYIDTLFVCSATAFMILFTGMYNTQAA
DGSFIVHQLKGVEAGPGFTQAAIDSVLPGFGAGFVAIALFFFAFTTIMAYYYIAETNIAYLARGRESKWAMLGLKLIILA
ATFYGTVKTASLAWALGDAGLGIMVWLNVIAIVLLAKPALLALKDYERQKKQGLDPIFDPKALGIKNADFWEKEYTHESE
RVS

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family

Homologues:

Organism=Escherichia coli, GI1786188, Length=475, Percent_Identity=40.6315789473684, Blast_Score=306, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YRBD_BACSU (O32060)

Other databases:

- EMBL:   Y15896
- EMBL:   AL009126
- PIR:   C69972
- RefSeq:   NP_390659.2
- EnsemblBacteria:   EBBACT00000002226
- GeneID:   937941
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU27810
- NMPDR:   fig|224308.1.peg.2784
- GenoList:   BSU27810
- GeneTree:   EBGT00070000031806
- HOGENOM:   HBG671706
- ProtClustDB:   CLSK502046
- BioCyc:   BSUB:BSU27810-MONOMER
- InterPro:   IPR001463
- PRINTS:   PR00175
- TIGRFAMs:   TIGR00835

Pfam domain/function: PF01235 Na_Ala_symp

EC number: NA

Molecular weight: Translated: 51510; Mature: 51379

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10eca3c0)-; HASH(0x1182e7b4)-; HASH(0x1155fcdc)-; HASH(0x11172a40)-; HASH(0x100b9f1c)-; HASH(0xd0f92a0)-; HASH(0x1156886c)-; HASH(0xedbe980)-; HASH(0x11408228)-; HASH(0x114cc4e0)-; HASH(0x1083a2b4)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFVASLNAVLWSTPVIYILLGIGFAFSIMTRFLQVRHLKEMIVQMFKGKSSEAGVSSF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
QALSIALSGRVGTGNIAGVATAIAFGGPGAVFWMWAIAFIGAASAFVESTLAQIYKVKQD
HHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GQYRGGPAYYIEKGLGIKWFAVLFAAAALIAMAFLMPGVQSNSIAAGIQNAFGISPFVTG
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHH
CGLVLLLGFIIFGGVKRIANAAQMIVPFMAIGYILLSLIIIVMNVSELPAVISLIFKSAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ALDSAFGGLIGMAISWGVKRGIYSNEAGQGTGPHPAAAAEVSHPVKQGLVQAFSVYIDTL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVCSATAFMILFTGMYNTQAADGSFIVHQLKGVEAGPGFTQAAIDSVLPGFGAGFVAIAL
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
FFFAFTTIMAYYYIAETNIAYLARGRESKWAMLGLKLIILAATFYGTVKTASLAWALGDA
HHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLGIMVWLNVIAIVLLAKPALLALKDYERQKKQGLDPIFDPKALGIKNADFWEKEYTHES
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCH
ERVS
HCCH
>Mature Secondary Structure 
ADFVASLNAVLWSTPVIYILLGIGFAFSIMTRFLQVRHLKEMIVQMFKGKSSEAGVSSF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH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HCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377