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The map label for this gene is yqjD

Identifier: 255767521

GI number: 255767521

Start: 2486813

End: 2488336

Strand: Reverse

Name: yqjD

Synonym: BSU23920

Alternate gene names: 255767521

Gene position: 2488336-2486813 (Counterclockwise)

Preceding gene: 255767522

Following gene: 255767520

Centisome position: 59.03

GC content: 48.88

Gene sequence:

>1524_bases
ATGAATGAGCACATGGATCATTTTTACACGAAACGCAAGCAGGCAGAAGAAGGCGGAGGACGGGAAAAGCTGGCTCAGCA
GCGGCAAAAGGGCAAGCTCACTGCTCGGGAAAGGATCATATTTCTTCTAGATCAGGACAGCTTTATCGAATTACACCCCT
TCATGGAAAGTCAAGTGTTAACAAGAGAACAGCGCATGTTAGGGGATGGGGTCGTGACAGGGTACGGCACAATTGACGGT
CGCTCAGTTTATGTATTTGCGCAAGACTTCACAGTGTACGGAGGGGCGCTTGGCGAAACCCATGCCAGGAAAATCTGCGC
TTTGATGGATCTGGCAGCAAAAAATAAGGCGCCGATTATCGGGCTGAATGACTCAGGTGGTGCGAGAATTCAAGAGGGTG
TGTTATCATTAGATGGATACGGTCACATATTTTACCGAAACGTCTTATATTCCGGAGTCATTCCGCAAATATCGGTTATT
TTAGGGCCGTGCGCTGGAGGCGCTGTATATTCTCCGGCACTCACAGATTTTATATTTATGGCTGAACAGACTGGCCGGAT
GTTTATTACCGGCCCGAAGGTGATTGAAAAAGTGACAGGGGAACAGGTTGATGCGGAGAGCTTAGGCGGAGCGGGGATAC
ATAATGCCGTCAGCGGAAACGCCCACTTTTCCGGGCATACGGAGAAGGAGGTTCTGACAGGGGTGAGAAAACTACTGTCT
TATTTGCCGCTGAATGGCCGGACAACAGAGCCGAAGCCAGAGAAAGAGGCGTCCAGACCGTTATTAAACCGTCTTGTCCC
TGCTGATACGACAAAGCCTTATGATGTTCGGAAGGTGATTAGGGAGCTGGCTGACCCGCAGTCTTTTTTTGAGATTCAGC
CATTTTTTGCGAAGAACATTGTCATTGGGTTTGCAAGGCTGGGTGAAAAAGCAATCGGCATCGTGGCGAGCCAGCCGAAG
CATCTGGCGGGAAGCCTGACGATTGACGCTGCTGATAAAGCAGCAAGGTTCATCCGTTTTTGTGACGCATTTGATATCCC
GCTGTTGACTGTCGAAGATGTCCCGGGGTTTCTGCCGGGTATTCAGCAAGAGCACAACGGAATCATCAGGCATGGAGCAA
AATTATTGTTTGCTTATGCTGAAGCGACTGTCCCAAAAGTCACACTCATCATTAGAAAAGCGTACGGCGGCGCCTATGTG
GCCATGAACAGCAAAGCGATCGGAGCGGACCTTGTGTTTGCATGGCCGAATGCTGAAATCGCAGTGATGGGTCCAGAAGG
TGCGGCATCGATTTTGTATGAAAAGGAAATCAAAGCTTCAGCTGACCCGCAAAAGACGAAACGCGAAAAAACTGCTGAAT
ACAAAAAGCAAAACGCCGGCCCATACAAAGCGGCCGCTTGTGGAATGGTCGATGACATCATTTTGCCGGAAGAATCAAGG
GGAAGACTGATTCAAGCTTTTCATATGCTTACACATAAGACAGAAGAGAGACCGAAAAAAAAGCACGGTAACATACCGCT
TTAA

Upstream 100 bases:

>100_bases
CAGGGAGCGAACGGGAAAAAGATCGCGTTTATTTCCCCTCGGGAAACAAACGGTGTTCTTGTAGAGCTTTGTGAACCGAA
AGGAGACCAACACAATGAGC

Downstream 100 bases:

>100_bases
TATGGAGGGACTTACAAATGGTGAATGAAAAACGCCTGCTGGAAGAATTTTTAGAGCTTGTCCAAATTGACTCAGAAACA
AAGCACGAAGCTGAAATCTG

Product: acyl-CoA carboxylase

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MNEHMDHFYTKRKQAEEGGGREKLAQQRQKGKLTARERIIFLLDQDSFIELHPFMESQVLTREQRMLGDGVVTGYGTIDG
RSVYVFAQDFTVYGGALGETHARKICALMDLAAKNKAPIIGLNDSGGARIQEGVLSLDGYGHIFYRNVLYSGVIPQISVI
LGPCAGGAVYSPALTDFIFMAEQTGRMFITGPKVIEKVTGEQVDAESLGGAGIHNAVSGNAHFSGHTEKEVLTGVRKLLS
YLPLNGRTTEPKPEKEASRPLLNRLVPADTTKPYDVRKVIRELADPQSFFEIQPFFAKNIVIGFARLGEKAIGIVASQPK
HLAGSLTIDAADKAARFIRFCDAFDIPLLTVEDVPGFLPGIQQEHNGIIRHGAKLLFAYAEATVPKVTLIIRKAYGGAYV
AMNSKAIGADLVFAWPNAEIAVMGPEGAASILYEKEIKASADPQKTKREKTAEYKKQNAGPYKAAACGMVDDIILPEESR
GRLIQAFHMLTHKTEERPKKKHGNIPL

Sequences:

>Translated_507_residues
MNEHMDHFYTKRKQAEEGGGREKLAQQRQKGKLTARERIIFLLDQDSFIELHPFMESQVLTREQRMLGDGVVTGYGTIDG
RSVYVFAQDFTVYGGALGETHARKICALMDLAAKNKAPIIGLNDSGGARIQEGVLSLDGYGHIFYRNVLYSGVIPQISVI
LGPCAGGAVYSPALTDFIFMAEQTGRMFITGPKVIEKVTGEQVDAESLGGAGIHNAVSGNAHFSGHTEKEVLTGVRKLLS
YLPLNGRTTEPKPEKEASRPLLNRLVPADTTKPYDVRKVIRELADPQSFFEIQPFFAKNIVIGFARLGEKAIGIVASQPK
HLAGSLTIDAADKAARFIRFCDAFDIPLLTVEDVPGFLPGIQQEHNGIIRHGAKLLFAYAEATVPKVTLIIRKAYGGAYV
AMNSKAIGADLVFAWPNAEIAVMGPEGAASILYEKEIKASADPQKTKREKTAEYKKQNAGPYKAAACGMVDDIILPEESR
GRLIQAFHMLTHKTEERPKKKHGNIPL
>Mature_507_residues
MNEHMDHFYTKRKQAEEGGGREKLAQQRQKGKLTARERIIFLLDQDSFIELHPFMESQVLTREQRMLGDGVVTGYGTIDG
RSVYVFAQDFTVYGGALGETHARKICALMDLAAKNKAPIIGLNDSGGARIQEGVLSLDGYGHIFYRNVLYSGVIPQISVI
LGPCAGGAVYSPALTDFIFMAEQTGRMFITGPKVIEKVTGEQVDAESLGGAGIHNAVSGNAHFSGHTEKEVLTGVRKLLS
YLPLNGRTTEPKPEKEASRPLLNRLVPADTTKPYDVRKVIRELADPQSFFEIQPFFAKNIVIGFARLGEKAIGIVASQPK
HLAGSLTIDAADKAARFIRFCDAFDIPLLTVEDVPGFLPGIQQEHNGIIRHGAKLLFAYAEATVPKVTLIIRKAYGGAYV
AMNSKAIGADLVFAWPNAEIAVMGPEGAASILYEKEIKASADPQKTKREKTAEYKKQNAGPYKAAACGMVDDIILPEESR
GRLIQAFHMLTHKTEERPKKKHGNIPL

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain

Homologues:

Organism=Homo sapiens, GI119943100, Length=518, Percent_Identity=51.5444015444015, Blast_Score=521, Evalue=1e-148,
Organism=Homo sapiens, GI295821216, Length=538, Percent_Identity=49.6282527881041, Blast_Score=509, Evalue=1e-144,
Organism=Homo sapiens, GI11545863, Length=497, Percent_Identity=33.4004024144869, Blast_Score=230, Evalue=2e-60,
Organism=Escherichia coli, GI1788655, Length=188, Percent_Identity=28.7234042553192, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147362, Length=505, Percent_Identity=50.8910891089109, Blast_Score=511, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI25147359, Length=505, Percent_Identity=50.8910891089109, Blast_Score=510, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI17552936, Length=514, Percent_Identity=33.6575875486381, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24586065, Length=501, Percent_Identity=33.3333333333333, Blast_Score=236, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PCCB_BACSU (P54541)

Other databases:

- EMBL:   D84432
- EMBL:   AL009126
- PIR:   D69963
- RefSeq:   NP_390272.2
- ProteinModelPortal:   P54541
- SMR:   P54541
- EnsemblBacteria:   EBBACT00000000289
- GeneID:   938685
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU23920
- NMPDR:   fig|224308.1.peg.2396
- GenoList:   BSU23920
- GeneTree:   EBGT00050000000003
- HOGENOM:   HBG461319
- ProtClustDB:   CLSK887539
- BioCyc:   BSUB:BSU23920-MONOMER
- BRENDA:   6.4.1.3
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762
- PRINTS:   PR01070

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.3

Molecular weight: Translated: 55476; Mature: 55476

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50989 COA_CT_CTER; PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEHMDHFYTKRKQAEEGGGREKLAQQRQKGKLTARERIIFLLDQDSFIELHPFMESQVL
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECEEEEEECCCCCEEECCCHHHHHH
TREQRMLGDGVVTGYGTIDGRSVYVFAQDFTVYGGALGETHARKICALMDLAAKNKAPII
HHHHHHHCCCEEEEEECCCCCEEEEEEECCEEECCCCCHHHHHHHHHHHHHHHCCCCCEE
GLNDSGGARIQEGVLSLDGYGHIFYRNVLYSGVIPQISVILGPCAGGAVYSPALTDFIFM
EECCCCCCHHHHCCEECCCCCHHHHHHHHHHCCCCEEEHEEECCCCCCCCCHHHHHHHHH
AEQTGRMFITGPKVIEKVTGEQVDAESLGGAGIHNAVSGNAHFSGHTEKEVLTGVRKLLS
HHCCCCEEEECHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YLPLNGRTTEPKPEKEASRPLLNRLVPADTTKPYDVRKVIRELADPQSFFEIQPFFAKNI
HCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHEECCHHHHHH
VIGFARLGEKAIGIVASQPKHLAGSLTIDAADKAARFIRFCDAFDIPLLTVEDVPGFLPG
HHHHHHHCCHHEEEEECCCCCCCCEEEEECHHHHHHHHHHHCCCCCCEEECCCCCCCCCC
IQQEHNGIIRHGAKLLFAYAEATVPKVTLIIRKAYGGAYVAMNSKAIGADLVFAWPNAEI
CCHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCCCCEEEEECCCCEE
AVMGPEGAASILYEKEIKASADPQKTKREKTAEYKKQNAGPYKAAACGMVDDIILPEESR
EEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHCCCCCCCC
GRLIQAFHMLTHKTEERPKKKHGNIPL
CHHHHHHHHHHHHHHHCHHHCCCCCCC
>Mature Secondary Structure
MNEHMDHFYTKRKQAEEGGGREKLAQQRQKGKLTARERIIFLLDQDSFIELHPFMESQVL
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECEEEEEECCCCCEEECCCHHHHHH
TREQRMLGDGVVTGYGTIDGRSVYVFAQDFTVYGGALGETHARKICALMDLAAKNKAPII
HHHHHHHCCCEEEEEECCCCCEEEEEEECCEEECCCCCHHHHHHHHHHHHHHHCCCCCEE
GLNDSGGARIQEGVLSLDGYGHIFYRNVLYSGVIPQISVILGPCAGGAVYSPALTDFIFM
EECCCCCCHHHHCCEECCCCCHHHHHHHHHHCCCCEEEHEEECCCCCCCCCHHHHHHHHH
AEQTGRMFITGPKVIEKVTGEQVDAESLGGAGIHNAVSGNAHFSGHTEKEVLTGVRKLLS
HHCCCCEEEECHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YLPLNGRTTEPKPEKEASRPLLNRLVPADTTKPYDVRKVIRELADPQSFFEIQPFFAKNI
HCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHEECCHHHHHH
VIGFARLGEKAIGIVASQPKHLAGSLTIDAADKAARFIRFCDAFDIPLLTVEDVPGFLPG
HHHHHHHCCHHEEEEECCCCCCCCEEEEECHHHHHHHHHHHCCCCCCEEECCCCCCCCCC
IQQEHNGIIRHGAKLLFAYAEATVPKVTLIIRKAYGGAYVAMNSKAIGADLVFAWPNAEI
CCHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCCCCEEEEECCCCEE
AVMGPEGAASILYEKEIKASADPQKTKREKTAEYKKQNAGPYKAAACGMVDDIILPEESR
EEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHCCCCCCCC
GRLIQAFHMLTHKTEERPKKKHGNIPL
CHHHHHHHHHHHHHHHCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377