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The map label for this gene is spoVK

Identifier: 255767408

GI number: 255767408

Start: 1874203

End: 1875171

Strand: Direct

Name: spoVK

Synonym: BSU17420

Alternate gene names: 255767408

Gene position: 1874203-1875171 (Clockwise)

Preceding gene: 16078803

Following gene: 255767409

Centisome position: 44.46

GC content: 44.17

Gene sequence:

>969_bases
ATGTTGGAGCGCGCTGTGACTTATAAAAACAACGGACAGATCAACATTATTCTGAACGGGCAAAAGCAGGTGCTGACGAA
TGCTGAGGCAGAGGCGGAATATCAGGCTGCATTGCAAAAAAACGAAGCAAAGCACGGCATTTTGAAGGAAATCGAAAAAG
AGATGAGCGCATTAGTTGGGATGGAGGAAATGAAACGCAACATCAAGGAAATATACGCCTGGATTTTTGTGAACCAAAAA
CGCGCGGAGCAAGGCTTGAAGGTTGGAAAGCAAGCGCTGCACATGATGTTTAAAGGAAATCCGGGAACGGGAAAAACGAC
GGTTGCACGGCTCATCGGCAAGCTGTTCTTTGAAATGAATGTCCTGTCAAAAGGCCACTTAATAGAAGCGGAGCGGGCTG
ACCTGGTCGGGGAGTATATCGGACACACCGCCCAAAAGACGAGAGATTTAATCAAAAAGTCATTAGGTGGCATTTTGTTT
ATAGACGAAGCCTACTCGCTGGCAAGAGGCGGCGAAAAGGACTTTGGGAAAGAAGCGATCGACACACTTGTAAAGCATAT
GGAAGACAAACAGCATGAGTTTATTTTGATACTCGCCGGATATTCACGGGAAATGGATCATTTTCTCTCGTTAAATCCCG
GACTCCAATCAAGATTTCCCATCTCCATTGATTTTCCGGATTACTCTGTGACCCAGCTCATGGAGATTGCGAAACGAATG
ATCGATGAAAGGGAATACCAGCTCAGTCAAGAAGCGGAATGGAAATTGAAAGATTACTTAATGACAGTGAAAAGCACGAC
AAGTCCCATTAAATTCAGCAATGGACGTTTTGTCAGAAATGTGATCGAAAAATCGATCAGAGCACAAGCCATGAGGCTTT
TAATGGGAGACCAATACTTAAAAAGCGACTTGATGACCATCAAAAGCCAAGATCTTTCCATTAAAGAAGAAGCATCTGGA
TCTGCATAG

Upstream 100 bases:

>100_bases
CTTATTGTTCCCGAAAAAAGCAATTGTTTCGACACATGATAGGCGTTTGTCACAATCGGCATCCGCTTGAATATCATATA
GAGAGAACAGAGAGGTGAAG

Downstream 100 bases:

>100_bases
ACCTCTCAGTTTTTGAGAGGTCTGTTTTTTGCTCGTATTTCCGCTTTTCAAAGCAATCGATTTGTGGTATACACATGCAG
GGTTTGGTATGATAATACTA

Product: mother cell sporulation ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MLERAVTYKNNGQINIILNGQKQVLTNAEAEAEYQAALQKNEAKHGILKEIEKEMSALVGMEEMKRNIKEIYAWIFVNQK
RAEQGLKVGKQALHMMFKGNPGTGKTTVARLIGKLFFEMNVLSKGHLIEAERADLVGEYIGHTAQKTRDLIKKSLGGILF
IDEAYSLARGGEKDFGKEAIDTLVKHMEDKQHEFILILAGYSREMDHFLSLNPGLQSRFPISIDFPDYSVTQLMEIAKRM
IDEREYQLSQEAEWKLKDYLMTVKSTTSPIKFSNGRFVRNVIEKSIRAQAMRLLMGDQYLKSDLMTIKSQDLSIKEEASG
SA

Sequences:

>Translated_322_residues
MLERAVTYKNNGQINIILNGQKQVLTNAEAEAEYQAALQKNEAKHGILKEIEKEMSALVGMEEMKRNIKEIYAWIFVNQK
RAEQGLKVGKQALHMMFKGNPGTGKTTVARLIGKLFFEMNVLSKGHLIEAERADLVGEYIGHTAQKTRDLIKKSLGGILF
IDEAYSLARGGEKDFGKEAIDTLVKHMEDKQHEFILILAGYSREMDHFLSLNPGLQSRFPISIDFPDYSVTQLMEIAKRM
IDEREYQLSQEAEWKLKDYLMTVKSTTSPIKFSNGRFVRNVIEKSIRAQAMRLLMGDQYLKSDLMTIKSQDLSIKEEASG
SA
>Mature_322_residues
MLERAVTYKNNGQINIILNGQKQVLTNAEAEAEYQAALQKNEAKHGILKEIEKEMSALVGMEEMKRNIKEIYAWIFVNQK
RAEQGLKVGKQALHMMFKGNPGTGKTTVARLIGKLFFEMNVLSKGHLIEAERADLVGEYIGHTAQKTRDLIKKSLGGILF
IDEAYSLARGGEKDFGKEAIDTLVKHMEDKQHEFILILAGYSREMDHFLSLNPGLQSRFPISIDFPDYSVTQLMEIAKRM
IDEREYQLSQEAEWKLKDYLMTVKSTTSPIKFSNGRFVRNVIEKSIRAQAMRLLMGDQYLKSDLMTIKSQDLSIKEEASG
SA

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cbxX/cfxQ family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SP5K_BACSU (P27643)

Other databases:

- EMBL:   X59412
- EMBL:   U66480
- EMBL:   AL009126
- PIR:   S16301
- RefSeq:   NP_389624.2
- ProteinModelPortal:   P27643
- SMR:   P27643
- EnsemblBacteria:   EBBACT00000003749
- GeneID:   940089
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU17420
- NMPDR:   fig|224308.1.peg.1746
- GenoList:   BSU17420
- GeneTree:   EBGT00050000001346
- HOGENOM:   HBG294702
- ProtClustDB:   CLSK873300
- BioCyc:   BSUB:BSU17420-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR000641
- InterPro:   IPR014232
- PRINTS:   PR00819
- SMART:   SM00382
- TIGRFAMs:   TIGR02881

Pfam domain/function: PF00004 AAA

EC number: 3.4.24.- [C]

Molecular weight: Translated: 36575; Mature: 36575

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERAVTYKNNGQINIILNGQKQVLTNAEAEAEYQAALQKNEAKHGILKEIEKEMSALVG
CCCCCEEECCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
MEEMKRNIKEIYAWIFVNQKRAEQGLKVGKQALHMMFKGNPGTGKTTVARLIGKLFFEMN
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VLSKGHLIEAERADLVGEYIGHTAQKTRDLIKKSLGGILFIDEAYSLARGGEKDFGKEAI
HCCCCCEECHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECHHHHHCCCCCCCCHHHH
DTLVKHMEDKQHEFILILAGYSREMDHFLSLNPGLQSRFPISIDFPDYSVTQLMEIAKRM
HHHHHHHCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHH
IDEREYQLSQEAEWKLKDYLMTVKSTTSPIKFSNGRFVRNVIEKSIRAQAMRLLMGDQYL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
KSDLMTIKSQDLSIKEEASGSA
HHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLERAVTYKNNGQINIILNGQKQVLTNAEAEAEYQAALQKNEAKHGILKEIEKEMSALVG
CCCCCEEECCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
MEEMKRNIKEIYAWIFVNQKRAEQGLKVGKQALHMMFKGNPGTGKTTVARLIGKLFFEMN
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VLSKGHLIEAERADLVGEYIGHTAQKTRDLIKKSLGGILFIDEAYSLARGGEKDFGKEAI
HCCCCCEECHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECHHHHHCCCCCCCCHHHH
DTLVKHMEDKQHEFILILAGYSREMDHFLSLNPGLQSRFPISIDFPDYSVTQLMEIAKRM
HHHHHHHCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHH
IDEREYQLSQEAEWKLKDYLMTVKSTTSPIKFSNGRFVRNVIEKSIRAQAMRLLMGDQYL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
KSDLMTIKSQDLSIKEEASGSA
HHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1787791; 9384377