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The map label for this gene is ymfD

Identifier: 255767382

GI number: 255767382

Start: 1755649

End: 1756857

Strand: Direct

Name: ymfD

Synonym: BSU16825

Alternate gene names: 255767382

Gene position: 1755649-1756857 (Clockwise)

Preceding gene: 16078744

Following gene: 255767383

Centisome position: 41.65

GC content: 41.27

Gene sequence:

>1209_bases
ATGAAAAATATTATTGCATTGTCTTCTGTCCCGCTTGTGATGACACTCGGGAACTCCATGCTGATTCCTGTTCTTCCGAT
GATGGAGAAAAAGCTGTCTGTGACTTCATTTCAAGTATCTTTAATCATTACTGTATATTCAGTAGTAGCAATTATTTGCA
TTCCGATTGCCGGATATTTGTCGGATCGTTTCGGGAGAAAAAAAATATTGCTTCCATGCCTCCTCATTGCAGGATTGGGG
GGAGCCGTAGCTGCTTTTGCCTCGACCTATATGAAAAATCCTTATGCTATGATCTTGGCGGGGCGGGTTCTTCAAGGCAT
TGGTTCTGCAGGTGCCGCTCCGATTGTCATGCCGTTTATCGGCGACCTGTTTAAAGGAGACGATGAAAAGGTCAGCGCGG
GTCTTGGCGATATTGAAACCGCCAACACGTCAGGGAAGGTACTGAGTCCCATACTTGGAGCCTTACTGGCTTCTTGGTAT
TGGTTTGTACCGTTTTGGTTTATTCCGTTTTTCTGTTTGATCAGCTTTTTGCTCGTATTGTTTTTGGTGGCCAAGCCTGA
AGAAGATGAAGATGCGCCTGCTGTTTCTGAGTTTATTAAGAGTGTGAAGAAAATTTTTAAACAGGATGGTCGCTGGCTTT
ATACGGTCTTCATTATCGGGTGTGTCATTATGTTTTTGTTATTTGGCGTATTATTTTATTTATCAGATACGCTGGAGAAC
AAGTATGCTATTGACGGAGTAGCTAAAGGCGGATTACTGGCAATCCCACTTTTGTTTTTGTCAACCAGTTCTTTTATAGC
TGGCAAAAAGATCGGTAAAGATAAAGGCCGAATGAAATTTTGCGTTGTTACAGGAATGATTCTGTTAACCCTTTCGTTTA
TTGCCTTGTGGTGGAACCACAGTTTTTATTTTTTATTTGTCTTTTTAAGCTTTGGCGGGATTGGGATTGGAATGGCTCTT
CCTGCTTTAGATGCATTGATAACCGAAGGGATTGAAAGTGAACAATGCGGAACCATTTCCTCCTTTTACAATAGCATGCG
CTTTATAGGAGTAGCTCTCGGTCCACCTGTTTTTGCTGCATTAATGTCTAATGCAAACTGGATTATTTTCATACTCTCGG
CGTTTTGCAGCATCGTTTCTTTATTTTTAGTGCTCTTTACTGTAGATGCTAAAAAAAGTGAAGAAGAAAAAAACTTAGGG
ACGGTCTAG

Upstream 100 bases:

>100_bases
TGATTCATGTTTCTTTGTACATACTTTCATTCCGGTTAACGCAATATATAAGGGATGACAAGAAAGTGAATGGGTGAAAA
TGTTGAGAGAGAAAAATGGA

Downstream 100 bases:

>100_bases
CCAGCCGTCTTTTTTTGCGCTTTCTTGCACAGTTTACAACTGTACCTATACAGCATGCGGAGGTTATTGTTTCCTTATAA
ATCCTACAGTTGCTATAATT

Product: multidrug resistance protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MKNIIALSSVPLVMTLGNSMLIPVLPMMEKKLSVTSFQVSLIITVYSVVAIICIPIAGYLSDRFGRKKILLPCLLIAGLG
GAVAAFASTYMKNPYAMILAGRVLQGIGSAGAAPIVMPFIGDLFKGDDEKVSAGLGDIETANTSGKVLSPILGALLASWY
WFVPFWFIPFFCLISFLLVLFLVAKPEEDEDAPAVSEFIKSVKKIFKQDGRWLYTVFIIGCVIMFLLFGVLFYLSDTLEN
KYAIDGVAKGGLLAIPLLFLSTSSFIAGKKIGKDKGRMKFCVVTGMILLTLSFIALWWNHSFYFLFVFLSFGGIGIGMAL
PALDALITEGIESEQCGTISSFYNSMRFIGVALGPPVFAALMSNANWIIFILSAFCSIVSLFLVLFTVDAKKSEEEKNLG
TV

Sequences:

>Translated_402_residues
MKNIIALSSVPLVMTLGNSMLIPVLPMMEKKLSVTSFQVSLIITVYSVVAIICIPIAGYLSDRFGRKKILLPCLLIAGLG
GAVAAFASTYMKNPYAMILAGRVLQGIGSAGAAPIVMPFIGDLFKGDDEKVSAGLGDIETANTSGKVLSPILGALLASWY
WFVPFWFIPFFCLISFLLVLFLVAKPEEDEDAPAVSEFIKSVKKIFKQDGRWLYTVFIIGCVIMFLLFGVLFYLSDTLEN
KYAIDGVAKGGLLAIPLLFLSTSSFIAGKKIGKDKGRMKFCVVTGMILLTLSFIALWWNHSFYFLFVFLSFGGIGIGMAL
PALDALITEGIESEQCGTISSFYNSMRFIGVALGPPVFAALMSNANWIIFILSAFCSIVSLFLVLFTVDAKKSEEEKNLG
TV
>Mature_402_residues
MKNIIALSSVPLVMTLGNSMLIPVLPMMEKKLSVTSFQVSLIITVYSVVAIICIPIAGYLSDRFGRKKILLPCLLIAGLG
GAVAAFASTYMKNPYAMILAGRVLQGIGSAGAAPIVMPFIGDLFKGDDEKVSAGLGDIETANTSGKVLSPILGALLASWY
WFVPFWFIPFFCLISFLLVLFLVAKPEEDEDAPAVSEFIKSVKKIFKQDGRWLYTVFIIGCVIMFLLFGVLFYLSDTLEN
KYAIDGVAKGGLLAIPLLFLSTSSFIAGKKIGKDKGRMKFCVVTGMILLTLSFIALWWNHSFYFLFVFLSFGGIGIGMAL
PALDALITEGIESEQCGTISSFYNSMRFIGVALGPPVFAALMSNANWIIFILSAFCSIVSLFLVLFTVDAKKSEEEKNLG
TV

Specific function: Involved in secretion of bacillibactin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BBEX_BACSU (O31762)

Other databases:

- EMBL:   AL009126
- PIR:   C69885
- PIR:   D69885
- RefSeq:   NP_389564.2
- ProteinModelPortal:   O31762
- SMR:   O31762
- EnsemblBacteria:   EBBACT00000001808
- GeneID:   939662
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU16825
- NMPDR:   fig|224308.1.peg.1685
- GenoList:   BSU16825
- GeneTree:   EBGT00070000031854
- ProtClustDB:   CLSK2523513
- BioCyc:   BSUB:BSU16825-MONOMER
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001958
- PRINTS:   PR01035

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 43676; Mature: 43676

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf4e879c)-; HASH(0xefe55ec)-; HASH(0xed69fbc)-; HASH(0xee3cc7c)-; HASH(0xe5eef40)-; HASH(0xf43b6ac)-; HASH(0xf438948)-; HASH(0xd00065c)-; HASH(0xf2f5580)-; HASH(0xef3bb9c)-; HASH(0xd1de218)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
>Mature Secondary Structure
MKNIIALSSVPLVMTLGNSMLIPVLPMMEKKLSVTSFQVSLIITVYSVVAIICIPIAGYL
CCCEEECCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDRFGRKKILLPCLLIAGLGGAVAAFASTYMKNPYAMILAGRVLQGIGSAGAAPIVMPFI
HHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHH
GDLFKGDDEKVSAGLGDIETANTSGKVLSPILGALLASWYWFVPFWFIPFFCLISFLLVL
HHHHCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLVAKPEEDEDAPAVSEFIKSVKKIFKQDGRWLYTVFIIGCVIMFLLFGVLFYLSDTLEN
HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
KYAIDGVAKGGLLAIPLLFLSTSSFIAGKKIGKDKGRMKFCVVTGMILLTLSFIALWWNH
CEEECCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
SFYFLFVFLSFGGIGIGMALPALDALITEGIESEQCGTISSFYNSMRFIGVALGPPVFAA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHH
LMSNANWIIFILSAFCSIVSLFLVLFTVDAKKSEEEKNLGTV
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377