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The map label for this gene is tepA

Identifier: 255767379

GI number: 255767379

Start: 1751201

End: 1751938

Strand: Direct

Name: tepA

Synonym: BSU16790

Alternate gene names: 255767379

Gene position: 1751201-1751938 (Clockwise)

Preceding gene: 255767378

Following gene: 255767380

Centisome position: 41.54

GC content: 43.36

Gene sequence:

>738_bases
ATGGATCATCGTATGGAAAACACAGAAGAAGAGCGTCCTGAAAAAAATGATGCGAAGGACAGCATTATGAATAAAATACA
GCAGCTTGGTGAAACGACGCTTCCGCAGCTGCCCCAAGATACAAATATTCATTGTCTGACCATTATCGGACAAATTGAAG
GCCATGTTCAGCTTCCTCCGCAAAACAAAACAACAAAATATGAACATGTCATCCCGCAGATTGTGGCAATTGAACAAAAT
CCCAAAATTGAAGGCTTGCTGATCATATTAAATACTGTCGGAGGAGATGTTGAAGCTGGTCTTGCCATAGCGGAAATGCT
TGCATCTTTATCGAAACCGACCGTTTCTATCGTGCTTGGCGGGGGGCATTCAATCGGCGTTCCGATTGCTGTATCCTGTG
ATTACAGCTATATCGCCGAAACAGCAACGATGACGATTCATCCAGTTAGGCTCACCGGGCTGGTCATCGGGGTGCCGCAA
ACGTTTGAATACCTGGATAAGATGCAAGAAAGAGTTGTTAAATTTGTGACAAGCCATTCCAATATAACCGAAGAGAAGTT
TAAAGAGCTAATGTTTTCAAAAGGAAACTTAACACGCGATATCGGAACAAATGTAGTCGGTAAGGATGCAGTTAAATACG
GATTGATCGATCACGCAGGCGGTGTCGGACAGGCAATCAATAAACTGAATGAGCTCATCGATGAAGCAAGGAAAGAAGAA
GGACGGATGATTCAATGA

Upstream 100 bases:

>100_bases
CGGAGCTGCTCCGGTCTTTATTTTTTGTCCTTCAAGCCGGGATTGAATGAAGTATCTTTGTTCATAATACAAAGAGAAAC
TCGGAAAGGATGAAAGCGAG

Downstream 100 bases:

>100_bases
TTCTTTATACCGTGATGCCTCAGGAAATTGTGTTTGCAGAACAGAACCAAGAGACAAGCGCACATGAGCAAATTGAATAT
AAAGGTGTACCGCTTCTAGT

Product: protein export-enhancing factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MDHRMENTEEERPEKNDAKDSIMNKIQQLGETTLPQLPQDTNIHCLTIIGQIEGHVQLPPQNKTTKYEHVIPQIVAIEQN
PKIEGLLIILNTVGGDVEAGLAIAEMLASLSKPTVSIVLGGGHSIGVPIAVSCDYSYIAETATMTIHPVRLTGLVIGVPQ
TFEYLDKMQERVVKFVTSHSNITEEKFKELMFSKGNLTRDIGTNVVGKDAVKYGLIDHAGGVGQAINKLNELIDEARKEE
GRMIQ

Sequences:

>Translated_245_residues
MDHRMENTEEERPEKNDAKDSIMNKIQQLGETTLPQLPQDTNIHCLTIIGQIEGHVQLPPQNKTTKYEHVIPQIVAIEQN
PKIEGLLIILNTVGGDVEAGLAIAEMLASLSKPTVSIVLGGGHSIGVPIAVSCDYSYIAETATMTIHPVRLTGLVIGVPQ
TFEYLDKMQERVVKFVTSHSNITEEKFKELMFSKGNLTRDIGTNVVGKDAVKYGLIDHAGGVGQAINKLNELIDEARKEE
GRMIQ
>Mature_245_residues
MDHRMENTEEERPEKNDAKDSIMNKIQQLGETTLPQLPQDTNIHCLTIIGQIEGHVQLPPQNKTTKYEHVIPQIVAIEQN
PKIEGLLIILNTVGGDVEAGLAIAEMLASLSKPTVSIVLGGGHSIGVPIAVSCDYSYIAETATMTIHPVRLTGLVIGVPQ
TFEYLDKMQERVVKFVTSHSNITEEKFKELMFSKGNLTRDIGTNVVGKDAVKYGLIDHAGGVGQAINKLNELIDEARKEE
GRMIQ

Specific function: Required for efficient translocation of pre-proteins across the membrane

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family. TepA subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TEPA_BACSU (Q99171)

Other databases:

- EMBL:   AL009126
- EMBL:   M17445
- PIR:   A69885
- RefSeq:   NP_389561.3
- ProteinModelPortal:   Q99171
- SMR:   Q99171
- MEROPS:   S14.001
- EnsemblBacteria:   EBBACT00000002631
- GeneID:   936370
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU16790
- NMPDR:   fig|224308.1.peg.1682
- GenoList:   BSU16790
- GeneTree:   EBGT00050000002297
- HOGENOM:   HBG304743
- ProtClustDB:   CLSK873313
- BioCyc:   BSUB:BSU16790-MONOMER
- GO:   GO:0005737
- GO:   GO:0006508
- InterPro:   IPR001907

Pfam domain/function: PF00574 CLP_protease

EC number: NA

Molecular weight: Translated: 26918; Mature: 26918

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: ACT_SITE 124-124 ACT_SITE 147-147

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHRMENTEEERPEKNDAKDSIMNKIQQLGETTLPQLPQDTNIHCLTIIGQIEGHVQLPP
CCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCEEECCC
QNKTTKYEHVIPQIVAIEQNPKIEGLLIILNTVGGDVEAGLAIAEMLASLSKPTVSIVLG
CCCCCHHHHHHHHHEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEE
GGHSIGVPIAVSCDYSYIAETATMTIHPVRLTGLVIGVPQTFEYLDKMQERVVKFVTSHS
CCCEECCEEEEECCHHHHHHHHEEEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCC
NITEEKFKELMFSKGNLTRDIGTNVVGKDAVKYGLIDHAGGVGQAINKLNELIDEARKEE
CCCHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHC
GRMIQ
CCCCC
>Mature Secondary Structure
MDHRMENTEEERPEKNDAKDSIMNKIQQLGETTLPQLPQDTNIHCLTIIGQIEGHVQLPP
CCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCEEECCC
QNKTTKYEHVIPQIVAIEQNPKIEGLLIILNTVGGDVEAGLAIAEMLASLSKPTVSIVLG
CCCCCHHHHHHHHHEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEE
GGHSIGVPIAVSCDYSYIAETATMTIHPVRLTGLVIGVPQTFEYLDKMQERVVKFVTSHS
CCCEECCEEEEECCHHHHHHHHEEEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCC
NITEEKFKELMFSKGNLTRDIGTNVVGKDAVKYGLIDHAGGVGQAINKLNELIDEARKEE
CCCHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHC
GRMIQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 3129532; 10455123