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The map label for this gene is ndhF [H]

Identifier: 239618439

GI number: 239618439

Start: 2206576

End: 2207412

Strand: Direct

Name: ndhF [H]

Synonym: Kole_2080

Alternate gene names: 239618439

Gene position: 2206576-2207412 (Clockwise)

Preceding gene: 239618438

Following gene: 239618440

Centisome position: 95.85

GC content: 42.05

Gene sequence:

>837_bases
GTGCTCCTCAATGTTAAAGAATTTTTGAAACCCACTTCGGTTGAACAGGCCTTTGAGATGCTGAACAGAGATAGAAAACA
TTCCATTCTTCTTTCAGGTGGAACAACGGTTTCCCTCATGAAATCGACCACTGTCGAAGTAATAATTGATCTCAAGAACA
TCAAAGAACTAGCCGAGATAAAAGAGACCGAAGATGGTTTGAGTGTTGGTGCTAATATCACCATAGAAGACTTTAGAAAG
TCTGATTTGATCTCCACATTTTTCGGAAATTTTTTCTCCAAAAGTTTTGCAACTGTTGGAAGTTGGCAAATACGTAACAT
GGCGACTATCGGTGGCTCCGTTGCACCGAGGCTTGGTTGGTCTGATGTAACAACCTGTCTTTTGGCTGCTGGAGCCAAAC
TTAAAACTTTTGGAGAAGAAGGCTATCGTTACATGGATATCGAAGATTTCAACAAGCTGGATAGGTACAGTAAGCCCATC
ATAACCCACGTTATTTTGCCCAAAGATGGCTATCTCTACTCTTTCAAGAAACTGTCGAAATCATCATTCGATATTGCCAT
CGTTAATTTTGCTCTCGCATTAAAACTAAATTCAGGAATTGTGGAAAGCTCGCGGGTGGTTATAGGCTCACGTCCGCACT
TCCCAAAGCGTTTCGAAAAGGTTGAACAAGCCCTCAAGGGGTTAAAAATTGAGGAAGTTCCAGAGCACGTTAAACCATTA
GTTTTTGAGCATTTTGAAGGCGGCAGTAATTTCCTCGCCACAGAAGAATACCGTAGGCACATGGCCTCTGTTTTGGCAGA
AAGAGCAGCAAAGGAAATTCGGGAGATGATAGCATGA

Upstream 100 bases:

>100_bases
CCTATTAGTGATATTCGTGCTTCCGCTTGGTACAGAAAAGAAGTTACCAAAAATCTGATCACTAAGATCATAGAACTCTG
GAATGAAAGGAGGGGGAGAT

Downstream 100 bases:

>100_bases
GGATAAGTCTAGAAGTTAATGGAAAACTTCATGAAGTCGAAATTGATCCAGGAGAAATGCTTCTGGATGTTTTGAGAAGA
CTTGGATATAAGAGTGTGAG

Product: molybdopterin dehydrogenase FAD-binding

Products: NA

Alternate protein names: NDH; Nicotinic acid hydroxylase FAD-subunit; NAH [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MLLNVKEFLKPTSVEQAFEMLNRDRKHSILLSGGTTVSLMKSTTVEVIIDLKNIKELAEIKETEDGLSVGANITIEDFRK
SDLISTFFGNFFSKSFATVGSWQIRNMATIGGSVAPRLGWSDVTTCLLAAGAKLKTFGEEGYRYMDIEDFNKLDRYSKPI
ITHVILPKDGYLYSFKKLSKSSFDIAIVNFALALKLNSGIVESSRVVIGSRPHFPKRFEKVEQALKGLKIEEVPEHVKPL
VFEHFEGGSNFLATEEYRRHMASVLAERAAKEIREMIA

Sequences:

>Translated_278_residues
MLLNVKEFLKPTSVEQAFEMLNRDRKHSILLSGGTTVSLMKSTTVEVIIDLKNIKELAEIKETEDGLSVGANITIEDFRK
SDLISTFFGNFFSKSFATVGSWQIRNMATIGGSVAPRLGWSDVTTCLLAAGAKLKTFGEEGYRYMDIEDFNKLDRYSKPI
ITHVILPKDGYLYSFKKLSKSSFDIAIVNFALALKLNSGIVESSRVVIGSRPHFPKRFEKVEQALKGLKIEEVPEHVKPL
VFEHFEGGSNFLATEEYRRHMASVLAERAAKEIREMIA
>Mature_278_residues
MLLNVKEFLKPTSVEQAFEMLNRDRKHSILLSGGTTVSLMKSTTVEVIIDLKNIKELAEIKETEDGLSVGANITIEDFRK
SDLISTFFGNFFSKSFATVGSWQIRNMATIGGSVAPRLGWSDVTTCLLAAGAKLKTFGEEGYRYMDIEDFNKLDRYSKPI
ITHVILPKDGYLYSFKKLSKSSFDIAIVNFALALKLNSGIVESSRVVIGSRPHFPKRFEKVEQALKGLKIEEVPEHVKPL
VFEHFEGGSNFLATEEYRRHMASVLAERAAKEIREMIA

Specific function: Catalyzes the hydroxylation of nicotinate to 6- hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=284, Percent_Identity=22.5352112676056, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789245, Length=266, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.17.1.5 [H]

Molecular weight: Translated: 31221; Mature: 31221

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLNVKEFLKPTSVEQAFEMLNRDRKHSILLSGGTTVSLMKSTTVEVIIDLKNIKELAEI
CCCCHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCEEEEECCCCEEEEEEHHHHHHHHHH
KETEDGLSVGANITIEDFRKSDLISTFFGNFFSKSFATVGSWQIRNMATIGGSVAPRLGW
HHCCCCHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHCCCCCCCCCCH
SDVTTCLLAAGAKLKTFGEEGYRYMDIEDFNKLDRYSKPIITHVILPKDGYLYSFKKLSK
HHHHHHHHHCCCHHHHHHCCCCEEECHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHCC
SSFDIAIVNFALALKLNSGIVESSRVVIGSRPHFPKRFEKVEQALKGLKIEEVPEHVKPL
CCCCEEEEHEEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
VFEHFEGGSNFLATEEYRRHMASVLAERAAKEIREMIA
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLLNVKEFLKPTSVEQAFEMLNRDRKHSILLSGGTTVSLMKSTTVEVIIDLKNIKELAEI
CCCCHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCEEEEECCCCEEEEEEHHHHHHHHHH
KETEDGLSVGANITIEDFRKSDLISTFFGNFFSKSFATVGSWQIRNMATIGGSVAPRLGW
HHCCCCHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHCCCCCCCCCCH
SDVTTCLLAAGAKLKTFGEEGYRYMDIEDFNKLDRYSKPIITHVILPKDGYLYSFKKLSK
HHHHHHHHHCCCHHHHHHCCCCEEECHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHCC
SSFDIAIVNFALALKLNSGIVESSRVVIGSRPHFPKRFEKVEQALKGLKIEEVPEHVKPL
CCCCEEEEHEEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
VFEHFEGGSNFLATEEYRRHMASVLAERAAKEIREMIA
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA