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The map label for this gene is hbpA [H]

Identifier: 239618406

GI number: 239618406

Start: 2175114

End: 2176619

Strand: Direct

Name: hbpA [H]

Synonym: Kole_2046

Alternate gene names: 239618406

Gene position: 2175114-2176619 (Clockwise)

Preceding gene: 239618403

Following gene: 239618407

Centisome position: 94.48

GC content: 45.09

Gene sequence:

>1506_bases
GTGAGAAAGTTTTTTGTTCTTCTTCTTGTACTCATACTTACCGTGTTCGTATTTGGACGAGACTACGTTACCGTGGGGAC
CACAGACAAGATAAGGATTCTTGACCCGGCAGATTGTTATGACTACTTCTCCAGCAATATACTGCAGAACACTATGGTAG
GCCTTGTTGACTACAAGGTGGGTACCTCTGAGCTTGTACCTTGGCTTGCAGAAAGTTGGGAGATTTCTGAGGACGGATTG
GTATACACATTCCATCTGAGAAAAGACGCGTACTTCATGAATGGGAATCCAATTGACGCAAACGCTCTCAAATTCTCAAT
CGACAGAGTTATAAGGCTCAACGGAGATCCGGCTTTCTTGCTTGCCGATGTTGTTGAAGAGACAAAGGTTGTAGATAAGT
ACACATTCCAGATAAAGCTTCAATACCCATTCTCAGCTTTCATCGCTGTTTTGGGGTACACAGTAGCCTATCCTGTTGAT
CCCGCAACGACACCGGCTGACGATTTCTTCTTCAACGCACCGGTAGCATCAGGTCCTTACTACATAGCTGATTGGGAACC
AGATGTACAGATTATACTGAAACGCAATCCGAAGTACTTTGGCCCTCCTCCCAAAACAGAGACGATCGTTATAAGGTTCT
ATCAGAACGCAAGCACTTTAAGGCTCGCGCTTGAAAGCGGAGAAATTGATGTGGCTTACAGAACTCTTGACCCCAGAGAT
CTCCTTATCCTGAAAATGGATCCGAGATACGTGGTTTACGAAGGTCAGAGTCCTGCAATTCGTGAGCTGGTGCTCAATGT
AAAGATGCCCCCATTCGACAACGTAAAAGTCAGAAAAGCTCTCGCTTACGCTGTGGATAGGGATGCTATCGTGAGTGATG
TGTTTGCGAATACTGTTGAACCTCTTTACACCCTTGTACCAATTGGAATGTGGTCTCATCTTGATGTGATGCCAAAACGC
GATCTTGCAAAGGCAAGAGAGCTTTTGAGAGAACTTGGCTACTCTGAATCCAACCCGCTCGAGATAACCCTTTGGTACAC
ACCCAGCCATTATGGTTCAACCGAAGCGGATGTTGCCCAGGTTCTAAAGGCTTCCATAGAGGAAACGGGTCTTGTCAAGG
TCGATATCAAATACGCCGAATGGGCAACCTATATCGACTACTTTGTCAGCGGTTCAATTGGAGCATTCTTGCTTGGCTGG
TATCCTGACTACCTTGATCCTGACGATTATCTGTGGCCGTTCCTTTCAAAATCAGGAGCCGCATCCATGGGATCTTTCTA
TGAGAGTCCCTTTGTAGAAAATCTCATGCTTCAGGCGAGAAAATACTCTGATATTGAGACAAGAACCAGCATAAACAAAG
ACGTGCAAAAAATCCTCGCCATAGACGTTCCTTACATTCCTCTGTGGCAGGGTAAGCAGTACTGTGTCTCTTATCCTTAC
GTCAAAGGTGTTGTACTGGAACCTTCTCAGATCTTCAGATACTATTTGCTTTATGTAGAAGAATAA

Upstream 100 bases:

>100_bases
TAGAATAATCTTTTAATTTGTCACTGTATGGTAAAATAAAAAATGTTAGACTCGTTATTAAAATCATGGGGAGTTGCACT
TTAAAAATGGGGGTGATTTT

Downstream 100 bases:

>100_bases
GTTGATTTTTAACCCGGGCCTTTCCCGGCCCGGGTTTTTTGTATTGTGCAGGAGGGGTTGCCGTGTCGTTGAAATGGTAC
GTGATTACCAGAATACTTTT

Product: extracellular solute-binding protein family 5

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MRKFFVLLLVLILTVFVFGRDYVTVGTTDKIRILDPADCYDYFSSNILQNTMVGLVDYKVGTSELVPWLAESWEISEDGL
VYTFHLRKDAYFMNGNPIDANALKFSIDRVIRLNGDPAFLLADVVEETKVVDKYTFQIKLQYPFSAFIAVLGYTVAYPVD
PATTPADDFFFNAPVASGPYYIADWEPDVQIILKRNPKYFGPPPKTETIVIRFYQNASTLRLALESGEIDVAYRTLDPRD
LLILKMDPRYVVYEGQSPAIRELVLNVKMPPFDNVKVRKALAYAVDRDAIVSDVFANTVEPLYTLVPIGMWSHLDVMPKR
DLAKARELLRELGYSESNPLEITLWYTPSHYGSTEADVAQVLKASIEETGLVKVDIKYAEWATYIDYFVSGSIGAFLLGW
YPDYLDPDDYLWPFLSKSGAASMGSFYESPFVENLMLQARKYSDIETRTSINKDVQKILAIDVPYIPLWQGKQYCVSYPY
VKGVVLEPSQIFRYYLLYVEE

Sequences:

>Translated_501_residues
MRKFFVLLLVLILTVFVFGRDYVTVGTTDKIRILDPADCYDYFSSNILQNTMVGLVDYKVGTSELVPWLAESWEISEDGL
VYTFHLRKDAYFMNGNPIDANALKFSIDRVIRLNGDPAFLLADVVEETKVVDKYTFQIKLQYPFSAFIAVLGYTVAYPVD
PATTPADDFFFNAPVASGPYYIADWEPDVQIILKRNPKYFGPPPKTETIVIRFYQNASTLRLALESGEIDVAYRTLDPRD
LLILKMDPRYVVYEGQSPAIRELVLNVKMPPFDNVKVRKALAYAVDRDAIVSDVFANTVEPLYTLVPIGMWSHLDVMPKR
DLAKARELLRELGYSESNPLEITLWYTPSHYGSTEADVAQVLKASIEETGLVKVDIKYAEWATYIDYFVSGSIGAFLLGW
YPDYLDPDDYLWPFLSKSGAASMGSFYESPFVENLMLQARKYSDIETRTSINKDVQKILAIDVPYIPLWQGKQYCVSYPY
VKGVVLEPSQIFRYYLLYVEE
>Mature_501_residues
MRKFFVLLLVLILTVFVFGRDYVTVGTTDKIRILDPADCYDYFSSNILQNTMVGLVDYKVGTSELVPWLAESWEISEDGL
VYTFHLRKDAYFMNGNPIDANALKFSIDRVIRLNGDPAFLLADVVEETKVVDKYTFQIKLQYPFSAFIAVLGYTVAYPVD
PATTPADDFFFNAPVASGPYYIADWEPDVQIILKRNPKYFGPPPKTETIVIRFYQNASTLRLALESGEIDVAYRTLDPRD
LLILKMDPRYVVYEGQSPAIRELVLNVKMPPFDNVKVRKALAYAVDRDAIVSDVFANTVEPLYTLVPIGMWSHLDVMPKR
DLAKARELLRELGYSESNPLEITLWYTPSHYGSTEADVAQVLKASIEETGLVKVDIKYAEWATYIDYFVSGSIGAFLLGW
YPDYLDPDDYLWPFLSKSGAASMGSFYESPFVENLMLQARKYSDIETRTSINKDVQKILAIDVPYIPLWQGKQYCVSYPY
VKGVVLEPSQIFRYYLLYVEE

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=468, Percent_Identity=29.7008547008547, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1787762, Length=509, Percent_Identity=26.7190569744597, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787052, Length=505, Percent_Identity=28.3168316831683, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI1787495, Length=505, Percent_Identity=26.9306930693069, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1787551, Length=489, Percent_Identity=25.3578732106339, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789887, Length=511, Percent_Identity=25.2446183953033, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1789397, Length=500, Percent_Identity=23.8, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87081878, Length=493, Percent_Identity=23.9350912778905, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57210; Mature: 57210

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFFVLLLVLILTVFVFGRDYVTVGTTDKIRILDPADCYDYFSSNILQNTMVGLVDYKV
CHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEECC
GTSELVPWLAESWEISEDGLVYTFHLRKDAYFMNGNPIDANALKFSIDRVIRLNGDPAFL
CHHHHHHHHHCCCCCCCCCEEEEEEEECCEEEECCCCCCCCCEEEEEEEEEEECCCCHHH
LADVVEETKVVDKYTFQIKLQYPFSAFIAVLGYTVAYPVDPATTPADDFFFNAPVASGPY
HHHHHHHHHHEEEEEEEEEEECCHHHHHHHHHHHEEECCCCCCCCCCCCEEECCCCCCCE
YIADWEPDVQIILKRNPKYFGPPPKTETIVIRFYQNASTLRLALESGEIDVAYRTLDPRD
EEECCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCEEEEEEECCCCE
LLILKMDPRYVVYEGQSPAIRELVLNVKMPPFDNVKVRKALAYAVDRDAIVSDVFANTVE
EEEEEECCCEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
PLYTLVPIGMWSHLDVMPKRDLAKARELLRELGYSESNPLEITLWYTPSHYGSTEADVAQ
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHH
VLKASIEETGLVKVDIKYAEWATYIDYFVSGSIGAFLLGWYPDYLDPDDYLWPFLSKSGA
HHHHHHHHCCEEEEEEEHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCHHHHHCCCCC
ASMGSFYESPFVENLMLQARKYSDIETRTSINKDVQKILAIDVPYIPLWQGKQYCVSYPY
CHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEECCC
VKGVVLEPSQIFRYYLLYVEE
EEEEEECHHHHEEEEEEEEEC
>Mature Secondary Structure
MRKFFVLLLVLILTVFVFGRDYVTVGTTDKIRILDPADCYDYFSSNILQNTMVGLVDYKV
CHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEECC
GTSELVPWLAESWEISEDGLVYTFHLRKDAYFMNGNPIDANALKFSIDRVIRLNGDPAFL
CHHHHHHHHHCCCCCCCCCEEEEEEEECCEEEECCCCCCCCCEEEEEEEEEEECCCCHHH
LADVVEETKVVDKYTFQIKLQYPFSAFIAVLGYTVAYPVDPATTPADDFFFNAPVASGPY
HHHHHHHHHHEEEEEEEEEEECCHHHHHHHHHHHEEECCCCCCCCCCCCEEECCCCCCCE
YIADWEPDVQIILKRNPKYFGPPPKTETIVIRFYQNASTLRLALESGEIDVAYRTLDPRD
EEECCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCEEEEEEECCCCE
LLILKMDPRYVVYEGQSPAIRELVLNVKMPPFDNVKVRKALAYAVDRDAIVSDVFANTVE
EEEEEECCCEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
PLYTLVPIGMWSHLDVMPKRDLAKARELLRELGYSESNPLEITLWYTPSHYGSTEADVAQ
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHH
VLKASIEETGLVKVDIKYAEWATYIDYFVSGSIGAFLLGWYPDYLDPDDYLWPFLSKSGA
HHHHHHHHCCEEEEEEEHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCHHHHHCCCCC
ASMGSFYESPFVENLMLQARKYSDIETRTSINKDVQKILAIDVPYIPLWQGKQYCVSYPY
CHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEECCC
VKGVVLEPSQIFRYYLLYVEE
EEEEEECHHHHEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]