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The map label for this gene is uppP

Identifier: 239618287

GI number: 239618287

Start: 2045545

End: 2046333

Strand: Reverse

Name: uppP

Synonym: Kole_1924

Alternate gene names: 239618287

Gene position: 2046333-2045545 (Counterclockwise)

Preceding gene: 239618288

Following gene: 239618286

Centisome position: 88.89

GC content: 39.92

Gene sequence:

>789_bases
GTGCTTGAGTTATGGAAATATACATTCCTCGGTATCGTTCAAGGGCTCACCGAGTTTTTGCCCGTTTCTTCTTCTGGTCA
TCTTACAGTCATTTCAAAACTGATGAATCTTAATTTAGAAACGGAAACTCTCAAAGCTTTTTTTGCACTACTACATCTCG
CCACTTTTTTTGCTGTTTTGTTTTTCACATACAAAGATGTCTGGAAAATAATCAGTGGTGTATTCAAGAAAAATGAACAA
CGTACTGCCTGGAAAATGATCGCATTGCTGTTGTTTGCCACACTTCCGGCGGTTGTTGTGGGATTAGGTTTCGAAAGTCA
GATCGACAAAGCTTTTTCTGGTATCGTCTTTCCGGCATTGATGCTTCTGGTAACTGCCTTTTTCCTTATATTAGCTGACA
GATTCAACGGCAACAAAAAGATCCTCGATTTAACGATTTACACCGCATTGATGATAGGTCTTTTTCAAGCAGTTGCTATT
CTTCCCGGAATATCCAGAAGTGGTATGACCGTTTTCGCAGCCCTTCTTTTTGGACTTTCAAGAGAAGATTCTGTAAGGTT
TTCTTTTCTTATGAGCCTGCCTGTAACCTTTGGGGCAGGAATTATTGAACTTTCAAAGGTATCAACTGAAACTCCCTACG
CAATCTCTGGATTCATTGCCGCTTTCTTTGCGGGCATTGTAGGATTATGGCTTCTGAAAAAATTCGTTCTACACGGGAAA
CTGCGAGGTTTTGCCTTTTACTGTATAATTGTTTCGTTGATTGTTTTATCAATATCGGGAGGGATTTAG

Upstream 100 bases:

>100_bases
GTCATAATTCGAACCGATGAAACAAATTTGAAAGAGATAGTTGAAGTTCTTCAAAGCAACAATATAAGCTTCGAAACGGT
AACAGAAGAGGAGGGATTCT

Downstream 100 bases:

>100_bases
GTGCGCTTCGATTTACTGTTTGCTGGGAGTTCCGTCTATGTTCCCGGTAAGATCGATGCACCATCTAGTTCTGCCGCATT
GCTGCGCGATGATGAAAAAA

Product: Bacitracin resistance protein BacA

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MLELWKYTFLGIVQGLTEFLPVSSSGHLTVISKLMNLNLETETLKAFFALLHLATFFAVLFFTYKDVWKIISGVFKKNEQ
RTAWKMIALLLFATLPAVVVGLGFESQIDKAFSGIVFPALMLLVTAFFLILADRFNGNKKILDLTIYTALMIGLFQAVAI
LPGISRSGMTVFAALLFGLSREDSVRFSFLMSLPVTFGAGIIELSKVSTETPYAISGFIAAFFAGIVGLWLLKKFVLHGK
LRGFAFYCIIVSLIVLSISGGI

Sequences:

>Translated_262_residues
MLELWKYTFLGIVQGLTEFLPVSSSGHLTVISKLMNLNLETETLKAFFALLHLATFFAVLFFTYKDVWKIISGVFKKNEQ
RTAWKMIALLLFATLPAVVVGLGFESQIDKAFSGIVFPALMLLVTAFFLILADRFNGNKKILDLTIYTALMIGLFQAVAI
LPGISRSGMTVFAALLFGLSREDSVRFSFLMSLPVTFGAGIIELSKVSTETPYAISGFIAAFFAGIVGLWLLKKFVLHGK
LRGFAFYCIIVSLIVLSISGGI
>Mature_262_residues
MLELWKYTFLGIVQGLTEFLPVSSSGHLTVISKLMNLNLETETLKAFFALLHLATFFAVLFFTYKDVWKIISGVFKKNEQ
RTAWKMIALLLFATLPAVVVGLGFESQIDKAFSGIVFPALMLLVTAFFLILADRFNGNKKILDLTIYTALMIGLFQAVAI
LPGISRSGMTVFAALLFGLSREDSVRFSFLMSLPVTFGAGIIELSKVSTETPYAISGFIAAFFAGIVGLWLLKKFVLHGK
LRGFAFYCIIVSLIVLSISGGI

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=257, Percent_Identity=33.4630350194552, Blast_Score=116, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_KOSOT (C5CGT6)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941609.1
- GeneID:   7968415
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_1924
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28839; Mature: 28839

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x28584d74)-; HASH(0x2a7c8b94)-; HASH(0x2a97f2b4)-; HASH(0x29bd7e98)-; HASH(0x2ab72474)-; HASH(0x2a9d13b8)-; HASH(0x2ac010bc)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA