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The map label for this gene is pilC [H]

Identifier: 239618229

GI number: 239618229

Start: 2002284

End: 2003486

Strand: Reverse

Name: pilC [H]

Synonym: Kole_1866

Alternate gene names: 239618229

Gene position: 2003486-2002284 (Counterclockwise)

Preceding gene: 239618230

Following gene: 239618228

Centisome position: 87.03

GC content: 41.56

Gene sequence:

>1203_bases
ATGCCGGAATATAGGTACGAAATAATCACCAAAGATGGAAAAACAGAAAGAGGAAAAATTAGCGCAGCTTCCCAACTTGA
AGCGTTGCAACTATTGAATAGCCAGGGATTCGTGGTTACATCCATCAAGCCAATTTCAAAGACCCGGAAAAGAAAAAGGT
CATTGTTCCCTATACAACCTAAAGAACTTAGCCTCTTTTCAAGACAGCTGGCAACGATGGTATCGTCAGGAGTTAGGATT
AGAGACGCACTACAGGTACTTTCAAAACAAACTATGTTTTCTCGTAGATTCAGAAAAATTTTGGTTGAAGTCGTTCTTTT
AATTGAATCAGGTGAAGGATTCAGCGATGCCCTTGAAAAAACACGCGTCTTTGATGAACTCTTTGTGAATCTTGTCAGAG
CTGGCGAAACTGGCGGCGTACTCGATGAGGCCTTACAAAGGGTTGCCGAATTCTACGAAGGAATGGTTGACCTTCAAAAC
CAGGTAAAATCAGCAATGTCTTATCCATTGTTCATGATGGCTTTTGCCGTTGGTATCGTTGGAGTTATTTCCTTCTTCAT
ACTACCAAATCTAATGAGTGCCTTTGGTACTGGATTTGAACCTGGCGGAGTTATGGGATTCCTCCTGTGGATGAATTCGC
TGCTGACAAATCATGGAGTAGTGGTTGCCATTGCAGTGGTAATGTTCTTTATAGGAGCCAAAATCTTCATGATGACAAAA
TACGGTCTGATCGTAAAAAATTTTTTTGGATCTATCATTCCACCTGTAAGAAAGTTACGAGAAACAACAGCCCTTGAGCG
TTTCACACGTACTCTAGCGGTTCTGGTGGCAAGTGGTGTGGATCTTCCAACATCCCTTGAACTCGCCGCCGAGGTTTCGG
AAAGCACCAAAATAATGAACGGAATTTCATTAGCTGTAGATATGATCAGAGCCGGGGAACCTATACACGTTTCGCTAGAA
AAGCAGAAGATATTCCCTTCCATCGTTATAAGCATGGTTTCAACAGGTGAGGAAACAGGTAAATTAGATGAAGTTATGTT
CAAAGTAGCGGATTTTTACCATGCGCAGGTAACTACCTCTCTCAAGAAACTCGTTTCCTTGGTTGAACCAATTATGATCA
TGTTTATCGGTGGATTTATTGGCTTCCTTGCTTACACAATGTACAACACAATTTTCTCGATGGAACAAGCAATGGGAGGA
TAA

Upstream 100 bases:

>100_bases
AAAGGGAATATAAATGTGAAACCAAAATCTGGAAATACTTTGTATGGAAATTCAGTGTCTGTATATGCTGTGTGTATGTT
AAAAAAGGTGGGGACATAGT

Downstream 100 bases:

>100_bases
CTTATAGCCATGAATCTCACGGAAACAGTACTGTATATTCTTTTAATCTCATTGGGAATGTTCTTAATCTCTTTCCCGAT
TATAAATTTCTTTGGGAGTT

Product: type II secretion system protein

Products: NA

Alternate protein names: Type IV-A pilus assembly protein pilC [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MPEYRYEIITKDGKTERGKISAASQLEALQLLNSQGFVVTSIKPISKTRKRKRSLFPIQPKELSLFSRQLATMVSSGVRI
RDALQVLSKQTMFSRRFRKILVEVVLLIESGEGFSDALEKTRVFDELFVNLVRAGETGGVLDEALQRVAEFYEGMVDLQN
QVKSAMSYPLFMMAFAVGIVGVISFFILPNLMSAFGTGFEPGGVMGFLLWMNSLLTNHGVVVAIAVVMFFIGAKIFMMTK
YGLIVKNFFGSIIPPVRKLRETTALERFTRTLAVLVASGVDLPTSLELAAEVSESTKIMNGISLAVDMIRAGEPIHVSLE
KQKIFPSIVISMVSTGEETGKLDEVMFKVADFYHAQVTTSLKKLVSLVEPIMIMFIGGFIGFLAYTMYNTIFSMEQAMGG

Sequences:

>Translated_400_residues
MPEYRYEIITKDGKTERGKISAASQLEALQLLNSQGFVVTSIKPISKTRKRKRSLFPIQPKELSLFSRQLATMVSSGVRI
RDALQVLSKQTMFSRRFRKILVEVVLLIESGEGFSDALEKTRVFDELFVNLVRAGETGGVLDEALQRVAEFYEGMVDLQN
QVKSAMSYPLFMMAFAVGIVGVISFFILPNLMSAFGTGFEPGGVMGFLLWMNSLLTNHGVVVAIAVVMFFIGAKIFMMTK
YGLIVKNFFGSIIPPVRKLRETTALERFTRTLAVLVASGVDLPTSLELAAEVSESTKIMNGISLAVDMIRAGEPIHVSLE
KQKIFPSIVISMVSTGEETGKLDEVMFKVADFYHAQVTTSLKKLVSLVEPIMIMFIGGFIGFLAYTMYNTIFSMEQAMGG
>Mature_399_residues
PEYRYEIITKDGKTERGKISAASQLEALQLLNSQGFVVTSIKPISKTRKRKRSLFPIQPKELSLFSRQLATMVSSGVRIR
DALQVLSKQTMFSRRFRKILVEVVLLIESGEGFSDALEKTRVFDELFVNLVRAGETGGVLDEALQRVAEFYEGMVDLQNQ
VKSAMSYPLFMMAFAVGIVGVISFFILPNLMSAFGTGFEPGGVMGFLLWMNSLLTNHGVVVAIAVVMFFIGAKIFMMTKY
GLIVKNFFGSIIPPVRKLRETTALERFTRTLAVLVASGVDLPTSLELAAEVSESTKIMNGISLAVDMIRAGEPIHVSLEK
QKIFPSIVISMVSTGEETGKLDEVMFKVADFYHAQVTTSLKKLVSLVEPIMIMFIGGFIGFLAYTMYNTIFSMEQAMGG

Specific function: Involved in the translocation of the type IV pilin [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=406, Percent_Identity=26.6009852216749, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786295, Length=412, Percent_Identity=27.6699029126214, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44284; Mature: 44153

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PEYRYEIITKDGKTERGKISAASQLEALQLLNSQGFVVTSIKPISKTRKRKRSLFPIQP
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCC
KELSLFSRQLATMVSSGVRIRDALQVLSKQTMFSRRFRKILVEVVLLIESGEGFSDALEK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
TRVFDELFVNLVRAGETGGVLDEALQRVAEFYEGMVDLQNQVKSAMSYPLFMMAFAVGIV
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GVISFFILPNLMSAFGTGFEPGGVMGFLLWMNSLLTNHGVVVAIAVVMFFIGAKIFMMTK
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YGLIVKNFFGSIIPPVRKLRETTALERFTRTLAVLVASGVDLPTSLELAAEVSESTKIMN
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
GISLAVDMIRAGEPIHVSLEKQKIFPSIVISMVSTGEETGKLDEVMFKVADFYHAQVTTS
HHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LKKLVSLVEPIMIMFIGGFIGFLAYTMYNTIFSMEQAMGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10024587; 10952301 [H]