Click here to switch to the map view.

The map label for this gene is wecA [H]

Identifier: 239618128

GI number: 239618128

Start: 1892789

End: 1893688

Strand: Direct

Name: wecA [H]

Synonym: Kole_1761

Alternate gene names: 239618128

Gene position: 1892789-1893688 (Clockwise)

Preceding gene: 239618127

Following gene: 239618131

Centisome position: 82.22

GC content: 39.78

Gene sequence:

>900_bases
ATGGAATTTTTATTAGCTTGTTCACTGTCCATCTTCATGACTTTTGTCTTCAGGCATATTGGAATAAAATTTGGATTTTT
AGATAAACCTGCCGGGAAACTCAAACCTCATGAAACAGCTATTCCCTATACCGGGGGTACAGCCATACTTTTGAGCCTTA
TCCCTTGGCTGATCCATGAACCGGGTTATATGGTTGTTGTTGTTTCACTCTGGGCGATAGGGTTTATAGATGATGTTAAA
GGATTGAATCCGTCTTTAAGGTTAATGATTGAACTTTTAGCAGGTTTTTTATTTTCTCTCTATTATCTAAACAACTCTTT
TTTTGAATCTCTGTTTCTTGCTTTCCTGTTTGCGGCTGTGGTAAATGCCTTCAACATGATAGATGGGATGGATGGTGTTT
GCAGCGGAGTGGTTGTTGTATCTGCGCTGGTTCTTGTTATAGTGTTTCAGTTACATCCACTTTTGCTTGCTTTTGCCGGG
ACTTTTTTTGGTTTTTTCGTCTGGAACTTTCCTCCAGCGAAGATATTCCTTGGTGATCAGGGTTCTTATATAGCCGGTGC
GTTTATGGGAATGATGCTTTTAAACAGTTACGGTACTGAATCATTTATACCGGTTTTAGCGGTGGTATGGTTGCCGTTAC
TTGATCTATCAGCTGGTTTCTTACGGAGGATTATTGCCGGAAAGTCTCCCTTTGAAGGGGATAGGGATCATTTTTACGAT
AAGCTCTTCTCACTCACAAAAGAAAACAAAAAAGCCACCACAATACTTTCTATTATGATGGCTTTTTTGTGGTCGGTTTT
GGGGCTTCTTCCCAACGCTATCATGAGTGTATCGCTTTTATGCTTGCTTTCAGTGGTTCTAGTGTTCAAGCTTAAACTCT
TAAAACAGCAGTCTATTTGA

Upstream 100 bases:

>100_bases
GAACTCTTGCGATTCCTTTTTTCAACGCTTTAACCCTTGAAGAACAAGAATACGTTGTCGAAACGCTAAAAAAAGCAATA
GAATTTGCAGGGTGAAGGCC

Downstream 100 bases:

>100_bases
ACCACTTTATTTTAAAGAGCGTAAAGCCAAATATCACCGCGGCAACCGCGGAAATTCCCATTGTTATGGCGAAAGCATAA
TCGTTACCACTGAGCGGTAG

Product: glycosyl transferase family 4

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MEFLLACSLSIFMTFVFRHIGIKFGFLDKPAGKLKPHETAIPYTGGTAILLSLIPWLIHEPGYMVVVVSLWAIGFIDDVK
GLNPSLRLMIELLAGFLFSLYYLNNSFFESLFLAFLFAAVVNAFNMIDGMDGVCSGVVVVSALVLVIVFQLHPLLLAFAG
TFFGFFVWNFPPAKIFLGDQGSYIAGAFMGMMLLNSYGTESFIPVLAVVWLPLLDLSAGFLRRIIAGKSPFEGDRDHFYD
KLFSLTKENKKATTILSIMMAFLWSVLGLLPNAIMSVSLLCLLSVVLVFKLKLLKQQSI

Sequences:

>Translated_299_residues
MEFLLACSLSIFMTFVFRHIGIKFGFLDKPAGKLKPHETAIPYTGGTAILLSLIPWLIHEPGYMVVVVSLWAIGFIDDVK
GLNPSLRLMIELLAGFLFSLYYLNNSFFESLFLAFLFAAVVNAFNMIDGMDGVCSGVVVVSALVLVIVFQLHPLLLAFAG
TFFGFFVWNFPPAKIFLGDQGSYIAGAFMGMMLLNSYGTESFIPVLAVVWLPLLDLSAGFLRRIIAGKSPFEGDRDHFYD
KLFSLTKENKKATTILSIMMAFLWSVLGLLPNAIMSVSLLCLLSVVLVFKLKLLKQQSI
>Mature_299_residues
MEFLLACSLSIFMTFVFRHIGIKFGFLDKPAGKLKPHETAIPYTGGTAILLSLIPWLIHEPGYMVVVVSLWAIGFIDDVK
GLNPSLRLMIELLAGFLFSLYYLNNSFFESLFLAFLFAAVVNAFNMIDGMDGVCSGVVVVSALVLVIVFQLHPLLLAFAG
TFFGFFVWNFPPAKIFLGDQGSYIAGAFMGMMLLNSYGTESFIPVLAVVWLPLLDLSAGFLRRIIAGKSPFEGDRDHFYD
KLFSLTKENKKATTILSIMMAFLWSVLGLLPNAIMSVSLLCLLSVVLVFKLKLLKQQSI

Specific function: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55), the lipid intermediate involved in the synthesis of various bacter

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. WecA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=276, Percent_Identity=26.8115942028986, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 33112; Mature: 33112

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLLACSLSIFMTFVFRHIGIKFGFLDKPAGKLKPHETAIPYTGGTAILLSLIPWLIHE
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
PGYMVVVVSLWAIGFIDDVKGLNPSLRLMIELLAGFLFSLYYLNNSFFESLFLAFLFAAV
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNAFNMIDGMDGVCSGVVVVSALVLVIVFQLHPLLLAFAGTFFGFFVWNFPPAKIFLGDQ
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
GSYIAGAFMGMMLLNSYGTESFIPVLAVVWLPLLDLSAGFLRRIIAGKSPFEGDRDHFYD
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
KLFSLTKENKKATTILSIMMAFLWSVLGLLPNAIMSVSLLCLLSVVLVFKLKLLKQQSI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEFLLACSLSIFMTFVFRHIGIKFGFLDKPAGKLKPHETAIPYTGGTAILLSLIPWLIHE
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
PGYMVVVVSLWAIGFIDDVKGLNPSLRLMIELLAGFLFSLYYLNNSFFESLFLAFLFAAV
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNAFNMIDGMDGVCSGVVVVSALVLVIVFQLHPLLLAFAGTFFGFFVWNFPPAKIFLGDQ
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
GSYIAGAFMGMMLLNSYGTESFIPVLAVVWLPLLDLSAGFLRRIIAGKSPFEGDRDHFYD
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
KLFSLTKENKKATTILSIMMAFLWSVLGLLPNAIMSVSLLCLLSVVLVFKLKLLKQQSI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]