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The map label for this gene is coaX

Identifier: 239618116

GI number: 239618116

Start: 1879940

End: 1880725

Strand: Direct

Name: coaX

Synonym: Kole_1748

Alternate gene names: 239618116

Gene position: 1879940-1880725 (Clockwise)

Preceding gene: 239618112

Following gene: 239618117

Centisome position: 81.66

GC content: 42.24

Gene sequence:

>786_bases
ATGAAGCTAGTTGCTGATGTTGGAAACACGAATACGGTGTTTGGCATATGGAACAGAGGAAAAATACTGAAAAATTGGAG
AATATCTACCGGCAGGCTGGAAACGGAAGATGAGATGTACGTTGTTTTGAAACAGCTTCTTGAAGCCGGGAATGTTGATT
TGAAGAGCATCGAAGATATATGCGTTGCGTCTGTTGTTCCAAGACTCAACAGTATTTTTCACTACTTTGGCAGAAAATAC
CTGGAACTTGATCCGGTGCTCGTTACCGCGATAGATGGAATCGGTGTGAAATGGGATGTCGATTTCCCATCCGAAATAGG
CGCGGATAGGGTGGCAAACGTTATAGGGGCCCACGAGTTTTATGGTAAGGACGCCATAGTAATCGATACCGGAACAGCTA
TAACCGTAGATGTCCTGAAAGATGGCGCCTTCATAGGAGGAGCTATTTTACCCGGCCCTATGATGGCCATGAGAGCTTTG
TTTTCAAAGACAGCTAAATTACCTGAGGTTGATTTGTTTTATGTAGAAAACCATATAGGGAAAAATACAGAAGACAATAT
AAGAATCGGTGTGGTAAACGGCACGTATTACGCTTTGAAGGCTATAATCTCCAAAGTAAAGGAAGAACTTGGCGATAAAA
TTCCCGTGATCGCAACCGGAGGTAATTCGCCAATGTTCAATATCGGAAATGGTTTTTTTGACATACTTGATTCCGATCTA
ACGCTAAAGGGAATCGCAGTTTTTTGCGAACGGGTGAGAAAACTTGAAAAAAATTCTGCTGGTTAA

Upstream 100 bases:

>100_bases
TAGCGAGTATCATTTTCTGCAGGTGCTCAAAAATGGATTTTCCTGGAGGTGCGGTGGTAGTAAGGGCGCCGACGTGATAA
CATTGAACTGGAGGGATTTT

Downstream 100 bases:

>100_bases
CCCGTGGATAGAAGATGTTTCAGCTTATGATTACTGGCTAAAACCTGTGGGTTTACTTTATATCTCTTCTATGCTTAGAT
CTGCGGGGATAGAGCCTGTA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKLVADVGNTNTVFGIWNRGKILKNWRISTGRLETEDEMYVVLKQLLEAGNVDLKSIEDICVASVVPRLNSIFHYFGRKY
LELDPVLVTAIDGIGVKWDVDFPSEIGADRVANVIGAHEFYGKDAIVIDTGTAITVDVLKDGAFIGGAILPGPMMAMRAL
FSKTAKLPEVDLFYVENHIGKNTEDNIRIGVVNGTYYALKAIISKVKEELGDKIPVIATGGNSPMFNIGNGFFDILDSDL
TLKGIAVFCERVRKLEKNSAG

Sequences:

>Translated_261_residues
MKLVADVGNTNTVFGIWNRGKILKNWRISTGRLETEDEMYVVLKQLLEAGNVDLKSIEDICVASVVPRLNSIFHYFGRKY
LELDPVLVTAIDGIGVKWDVDFPSEIGADRVANVIGAHEFYGKDAIVIDTGTAITVDVLKDGAFIGGAILPGPMMAMRAL
FSKTAKLPEVDLFYVENHIGKNTEDNIRIGVVNGTYYALKAIISKVKEELGDKIPVIATGGNSPMFNIGNGFFDILDSDL
TLKGIAVFCERVRKLEKNSAG
>Mature_261_residues
MKLVADVGNTNTVFGIWNRGKILKNWRISTGRLETEDEMYVVLKQLLEAGNVDLKSIEDICVASVVPRLNSIFHYFGRKY
LELDPVLVTAIDGIGVKWDVDFPSEIGADRVANVIGAHEFYGKDAIVIDTGTAITVDVLKDGAFIGGAILPGPMMAMRAL
FSKTAKLPEVDLFYVENHIGKNTEDNIRIGVVNGTYYALKAIISKVKEELGDKIPVIATGGNSPMFNIGNGFFDILDSDL
TLKGIAVFCERVRKLEKNSAG

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_KOSOT (C5CFU0)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941438.1
- GeneID:   7968235
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_1748
- ProtClustDB:   PRK13318
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28542; Mature: 28542

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 132-132 BINDING 183-183

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVADVGNTNTVFGIWNRGKILKNWRISTGRLETEDEMYVVLKQLLEAGNVDLKSIEDI
CEEEEECCCCCEEEEEECCCEEEECEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
CVASVVPRLNSIFHYFGRKYLELDPVLVTAIDGIGVKWDVDFPSEIGADRVANVIGAHEF
HHHHHHHHHHHHHHHHCCHHEEECCEEEEEECCCCEEEECCCCHHHCHHHHHHHHHHHHH
YGKDAIVIDTGTAITVDVLKDGAFIGGAILPGPMMAMRALFSKTAKLPEVDLFYVENHIG
HCCCEEEEECCCEEEEEEECCCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHCC
KNTEDNIRIGVVNGTYYALKAIISKVKEELGDKIPVIATGGNSPMFNIGNGFFDILDSDL
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCHHHHHCCCC
TLKGIAVFCERVRKLEKNSAG
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLVADVGNTNTVFGIWNRGKILKNWRISTGRLETEDEMYVVLKQLLEAGNVDLKSIEDI
CEEEEECCCCCEEEEEECCCEEEECEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
CVASVVPRLNSIFHYFGRKYLELDPVLVTAIDGIGVKWDVDFPSEIGADRVANVIGAHEF
HHHHHHHHHHHHHHHHCCHHEEECCEEEEEECCCCEEEECCCCHHHCHHHHHHHHHHHHH
YGKDAIVIDTGTAITVDVLKDGAFIGGAILPGPMMAMRALFSKTAKLPEVDLFYVENHIG
HCCCEEEEECCCEEEEEEECCCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHCC
KNTEDNIRIGVVNGTYYALKAIISKVKEELGDKIPVIATGGNSPMFNIGNGFFDILDSDL
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCHHHHHCCCC
TLKGIAVFCERVRKLEKNSAG
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA