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The map label for this gene is glnM [H]

Identifier: 239618043

GI number: 239618043

Start: 1806502

End: 1807236

Strand: Direct

Name: glnM [H]

Synonym: Kole_1672

Alternate gene names: 239618043

Gene position: 1806502-1807236 (Clockwise)

Preceding gene: 239618042

Following gene: 239618044

Centisome position: 78.47

GC content: 42.45

Gene sequence:

>735_bases
ATGCTGAAGTTCATGTCCAGAGTGCTTTTAGTGATCACGGTAACTTTGATATTCTTTTCTATTTACGCCTCCCTTTCGAA
GGTGTATCCCTTTAATTGGTCGGTGATACTGAAGTATCGCCGACTCTTTTTTGATGGATTGATGACAACACTCCGGTTGA
GTGTTACAGCGCTTGGGTTGTCACTCTTGGTGGGTTTTATAATAGCACTTTTTAGAACTTCCAGGATTTTAGTTCTGGAA
GAGCTCGGTATGATTTATGTTTGGTTTTTCCGAAATATGCCTCTTCTTGTAATCATTCTCCTGATCTACTACGGAATTGG
TTCTGTGGTAGCAATAAACCGTTTTTGGGCGGGAGTGATTTCCCTAGCACTTTTTGAAGGTGCTTATGTAGGTGAAATAT
TCCGTGCAGGAATAGAAGCCGTCCCTCGTGGCGAAATTGAAGCTGGTGAAGCATTGGGAATGTATAAATATCAGATCATG
GGATCGATTATTTTTCCAAGGGCTTTAAGGATTTCCATTCCACCTCTTGTCGGACAGATGGTGAGTCTTGTAAAGGATAG
TTCTCTCGTCTCAGTAATTGCACTTGGTGATTTGACTATGAGAGCAAGGCAGGTAGGTACTCAAACACTTGCAAGCCTTG
AAGCGTATCTAGTGCTGGCAGGATTTTACTTAGCCATAACCTCCCTTCTTTCCTTGGTCGGGAGGTATTTAGAAAGGAGG
TTGGCTATACCATGA

Upstream 100 bases:

>100_bases
CAATTTTATCGAAGGACTTAAATCATCAGGATTCATGGAACTCCTGGAAGAAAAGTGGTTTGTTGAATATGAACCAGAAT
TGTAAGTATGAGGTGAAAAG

Downstream 100 bases:

>100_bases
ATTCTCTTGTTTTAAGTGTCAAGAATATCTCACAGTTCTTTGGTTCTTTTCAGGTATTAAAAAATGTATCAATCGATATA
CATCAAGGTGATGTTGTAGC

Product: polar amino acid ABC transporter, inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MLKFMSRVLLVITVTLIFFSIYASLSKVYPFNWSVILKYRRLFFDGLMTTLRLSVTALGLSLLVGFIIALFRTSRILVLE
ELGMIYVWFFRNMPLLVIILLIYYGIGSVVAINRFWAGVISLALFEGAYVGEIFRAGIEAVPRGEIEAGEALGMYKYQIM
GSIIFPRALRISIPPLVGQMVSLVKDSSLVSVIALGDLTMRARQVGTQTLASLEAYLVLAGFYLAITSLLSLVGRYLERR
LAIP

Sequences:

>Translated_244_residues
MLKFMSRVLLVITVTLIFFSIYASLSKVYPFNWSVILKYRRLFFDGLMTTLRLSVTALGLSLLVGFIIALFRTSRILVLE
ELGMIYVWFFRNMPLLVIILLIYYGIGSVVAINRFWAGVISLALFEGAYVGEIFRAGIEAVPRGEIEAGEALGMYKYQIM
GSIIFPRALRISIPPLVGQMVSLVKDSSLVSVIALGDLTMRARQVGTQTLASLEAYLVLAGFYLAITSLLSLVGRYLERR
LAIP
>Mature_244_residues
MLKFMSRVLLVITVTLIFFSIYASLSKVYPFNWSVILKYRRLFFDGLMTTLRLSVTALGLSLLVGFIIALFRTSRILVLE
ELGMIYVWFFRNMPLLVIILLIYYGIGSVVAINRFWAGVISLALFEGAYVGEIFRAGIEAVPRGEIEAGEALGMYKYQIM
GSIIFPRALRISIPPLVGQMVSLVKDSSLVSVIALGDLTMRARQVGTQTLASLEAYLVLAGFYLAITSLLSLVGRYLERR
LAIP

Specific function: Part of the ABC transporter complex glnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=225, Percent_Identity=35.1111111111111, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1788226, Length=193, Percent_Identity=34.1968911917098, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787030, Length=216, Percent_Identity=32.4074074074074, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786874, Length=236, Percent_Identity=28.8135593220339, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI87082239, Length=206, Percent_Identity=30.5825242718447, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787087, Length=217, Percent_Identity=28.110599078341, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788646, Length=215, Percent_Identity=29.7674418604651, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI48994930, Length=138, Percent_Identity=36.9565217391304, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788645, Length=223, Percent_Identity=30.0448430493274, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787086, Length=221, Percent_Identity=30.316742081448, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27239; Mature: 27239

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFMSRVLLVITVTLIFFSIYASLSKVYPFNWSVILKYRRLFFDGLMTTLRLSVTALGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLVGFIIALFRTSRILVLEELGMIYVWFFRNMPLLVIILLIYYGIGSVVAINRFWAGVI
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLALFEGAYVGEIFRAGIEAVPRGEIEAGEALGMYKYQIMGSIIFPRALRISIPPLVGQM
HHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHEECCHHHHHH
VSLVKDSSLVSVIALGDLTMRARQVGTQTLASLEAYLVLAGFYLAITSLLSLVGRYLERR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIP
CCCC
>Mature Secondary Structure
MLKFMSRVLLVITVTLIFFSIYASLSKVYPFNWSVILKYRRLFFDGLMTTLRLSVTALGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLVGFIIALFRTSRILVLEELGMIYVWFFRNMPLLVIILLIYYGIGSVVAINRFWAGVI
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLALFEGAYVGEIFRAGIEAVPRGEIEAGEALGMYKYQIMGSIIFPRALRISIPPLVGQM
HHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHEECCHHHHHH
VSLVKDSSLVSVIALGDLTMRARQVGTQTLASLEAYLVLAGFYLAITSLLSLVGRYLERR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 9384377 [H]