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The map label for this gene is yoeA [H]

Identifier: 239618039

GI number: 239618039

Start: 1801371

End: 1802708

Strand: Direct

Name: yoeA [H]

Synonym: Kole_1668

Alternate gene names: 239618039

Gene position: 1801371-1802708 (Clockwise)

Preceding gene: 239618038

Following gene: 239618042

Centisome position: 78.25

GC content: 42.9

Gene sequence:

>1338_bases
GTGCAGAGAGTTTATATATTGAATGAGCAGATGACACCGGCATTGTTTAAACTTGCGTGGCCTACCATCCTTTCTATGCT
GTTCCAGACGCTGTACAACGTCATAGATGCTTTCTGGCTGGGAAAGTTGGGAAAGATAGCCATTTCAGCTCCAACGATAG
CGTGGCCTGCCATATTTCTTTTGATTTCTCTTGGGAGTGGTCTCGGGGTTGCCGGACTTGCGATGGTATCCCAGTATGTT
GGGGCGGGGGATTTCAAGAAAGCGTCAAAAGCTGCAGGACAGATCATATTGATAAGTACAATATTTGCGACAGTTATTGG
GATTATTGGTGGAATATTCAGTGGTGGTATTTTGAAGCTCATGAGGATTCCACCGGAGATGTTTGACAGCACCAGGATCT
ATATGCAAACCATATTCTTTGGTGCCCCATTAACCTTTGGAACTTTTGCTATTGCGTCCCTGTTTTCCGGTTGGGGTGAT
ACAGTTACCCCAATGATATTAACGGGTCTGTCGGTTCTTTTCAACGCCGTGCTAGACCCTCTGATGATTTTCGGTATCGG
TTTTCCTCGGTTTGAAGTATTTGGAGCTGCACTGGCAACAGTTATATCCCGTGGAGTGGTTGTCATTTTCGCGCTGTACA
TACTTTTTAGTGGTAGACGGGGAATAAAACTGACGTTTCACGATATGGTGCCAGATGTTTATATGATCAAGAAAATATTT
TCAATTGGGTTTCCATCATCGTTGGGGCAATCAGTTACCGCTTTTGCCTTTTTAATAATAATGGCAATAATATCCAGATT
TGGGCCTGTTGCCACTGCTGCAGTGGGTGTTGGTAATAGGGTTACTTCTATTGCGACAATGTTTTCTTTCGGCCTTGCAC
AGGCAACATCAGCTATGGTTGGTCAGTACCTCGGGGCAGAAAGAAATGACGATGCTTACAGGGTTGTATGGAAATCTGCG
GGAATAAATATGGTTATTGTGGGTGCTATGTGTACTGGAACTTTTTTCTTTGGCAAAGAAGTAACCGCGTTCTTTATAAA
TGAACCGGATGTACTGGTTGAGGGATTCCGGTATTTTCGGATCGTGTCTCTTTCAATTCCATTTTATGCCACTTTCAATA
TATTCGATGCTGCTTTGAGGGGTTCCGGTTATACGGTCGCTTCTATGATTTTGAATATCGTCAGGCTTTGGGGTATACGC
CTACCTCTAATATACTTATTTGGGTTGTCAATGGGAACTCTTGGAATCTGGTATGCAATGCTGATCAGTAACATTTCTAT
CGCAATTGCAGCTGCTTTTGTTATAAGTTCTAAAAAATGGCTTAAAAAGGTGATATAG

Upstream 100 bases:

>100_bases
TTTCCCCGGGGCTATTTAAGCTCCGGGCTTTTTTTGAGTATGGTGCGGAAAAATCATGTATAATTGCTTCTGATTGCTAA
CTTTTTGGGGGTAAGTATCA

Downstream 100 bases:

>100_bases
AGAACAAAAGCCGTGGATACGCCACAGCTTTTGTTCTGTTTTTTTTGAGGGTGAATTAGACAGTGATCAGAGAAAGAGTC
TCTTCGTAATCATCAAGCCA

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MQRVYILNEQMTPALFKLAWPTILSMLFQTLYNVIDAFWLGKLGKIAISAPTIAWPAIFLLISLGSGLGVAGLAMVSQYV
GAGDFKKASKAAGQIILISTIFATVIGIIGGIFSGGILKLMRIPPEMFDSTRIYMQTIFFGAPLTFGTFAIASLFSGWGD
TVTPMILTGLSVLFNAVLDPLMIFGIGFPRFEVFGAALATVISRGVVVIFALYILFSGRRGIKLTFHDMVPDVYMIKKIF
SIGFPSSLGQSVTAFAFLIIMAIISRFGPVATAAVGVGNRVTSIATMFSFGLAQATSAMVGQYLGAERNDDAYRVVWKSA
GINMVIVGAMCTGTFFFGKEVTAFFINEPDVLVEGFRYFRIVSLSIPFYATFNIFDAALRGSGYTVASMILNIVRLWGIR
LPLIYLFGLSMGTLGIWYAMLISNISIAIAAAFVISSKKWLKKVI

Sequences:

>Translated_445_residues
MQRVYILNEQMTPALFKLAWPTILSMLFQTLYNVIDAFWLGKLGKIAISAPTIAWPAIFLLISLGSGLGVAGLAMVSQYV
GAGDFKKASKAAGQIILISTIFATVIGIIGGIFSGGILKLMRIPPEMFDSTRIYMQTIFFGAPLTFGTFAIASLFSGWGD
TVTPMILTGLSVLFNAVLDPLMIFGIGFPRFEVFGAALATVISRGVVVIFALYILFSGRRGIKLTFHDMVPDVYMIKKIF
SIGFPSSLGQSVTAFAFLIIMAIISRFGPVATAAVGVGNRVTSIATMFSFGLAQATSAMVGQYLGAERNDDAYRVVWKSA
GINMVIVGAMCTGTFFFGKEVTAFFINEPDVLVEGFRYFRIVSLSIPFYATFNIFDAALRGSGYTVASMILNIVRLWGIR
LPLIYLFGLSMGTLGIWYAMLISNISIAIAAAFVISSKKWLKKVI
>Mature_445_residues
MQRVYILNEQMTPALFKLAWPTILSMLFQTLYNVIDAFWLGKLGKIAISAPTIAWPAIFLLISLGSGLGVAGLAMVSQYV
GAGDFKKASKAAGQIILISTIFATVIGIIGGIFSGGILKLMRIPPEMFDSTRIYMQTIFFGAPLTFGTFAIASLFSGWGD
TVTPMILTGLSVLFNAVLDPLMIFGIGFPRFEVFGAALATVISRGVVVIFALYILFSGRRGIKLTFHDMVPDVYMIKKIF
SIGFPSSLGQSVTAFAFLIIMAIISRFGPVATAAVGVGNRVTSIATMFSFGLAQATSAMVGQYLGAERNDDAYRVVWKSA
GINMVIVGAMCTGTFFFGKEVTAFFINEPDVLVEGFRYFRIVSLSIPFYATFNIFDAALRGSGYTVASMILNIVRLWGIR
LPLIYLFGLSMGTLGIWYAMLISNISIAIAAAFVISSKKWLKKVI

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=447, Percent_Identity=20.5816554809843, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48246; Mature: 48246

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRVYILNEQMTPALFKLAWPTILSMLFQTLYNVIDAFWLGKLGKIAISAPTIAWPAIFL
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHH
LISLGSGLGVAGLAMVSQYVGAGDFKKASKAAGQIILISTIFATVIGIIGGIFSGGILKL
HHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
MRIPPEMFDSTRIYMQTIFFGAPLTFGTFAIASLFSGWGDTVTPMILTGLSVLFNAVLDP
HHCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LMIFGIGFPRFEVFGAALATVISRGVVVIFALYILFSGRRGIKLTFHDMVPDVYMIKKIF
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCHHHHHHHHH
SIGFPSSLGQSVTAFAFLIIMAIISRFGPVATAAVGVGNRVTSIATMFSFGLAQATSAMV
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GQYLGAERNDDAYRVVWKSAGINMVIVGAMCTGTFFFGKEVTAFFINEPDVLVEGFRYFR
HHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHEECCCEEEEEECCCHHHHHHHHHHE
IVSLSIPFYATFNIFDAALRGSGYTVASMILNIVRLWGIRLPLIYLFGLSMGTLGIWYAM
EEEEECCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISNISIAIAAAFVISSKKWLKKVI
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQRVYILNEQMTPALFKLAWPTILSMLFQTLYNVIDAFWLGKLGKIAISAPTIAWPAIFL
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHH
LISLGSGLGVAGLAMVSQYVGAGDFKKASKAAGQIILISTIFATVIGIIGGIFSGGILKL
HHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
MRIPPEMFDSTRIYMQTIFFGAPLTFGTFAIASLFSGWGDTVTPMILTGLSVLFNAVLDP
HHCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LMIFGIGFPRFEVFGAALATVISRGVVVIFALYILFSGRRGIKLTFHDMVPDVYMIKKIF
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCHHHHHHHHH
SIGFPSSLGQSVTAFAFLIIMAIISRFGPVATAAVGVGNRVTSIATMFSFGLAQATSAMV
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GQYLGAERNDDAYRVVWKSAGINMVIVGAMCTGTFFFGKEVTAFFINEPDVLVEGFRYFR
HHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHEECCCEEEEEECCCHHHHHHHHHHE
IVSLSIPFYATFNIFDAALRGSGYTVASMILNIVRLWGIRLPLIYLFGLSMGTLGIWYAM
EEEEECCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISNISIAIAAAFVISSKKWLKKVI
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]