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The map label for this gene is walR [H]

Identifier: 239617943

GI number: 239617943

Start: 1683977

End: 1684696

Strand: Direct

Name: walR [H]

Synonym: Kole_1571

Alternate gene names: 239617943

Gene position: 1683977-1684696 (Clockwise)

Preceding gene: 239617942

Following gene: 239617944

Centisome position: 73.15

GC content: 43.19

Gene sequence:

>720_bases
GTGGCCAAAAAGAACATATTGGTAATTGATGATGAGCCATCGATCGTCGAGCTTCTTAGTTTCAACCTCAAGAAAGAGGG
ATATGATGTCTTAAAGGCTTATGATGCCGAGGAAGCTCTCAAAATTGTAGAGGACAACGATGTTGACATGTTCATAGTAG
ACATCATGCTTCCTGGAATGGACGGTTTTGAATTGGTAAGAAACCTGAGGAGTACGGAAAAACACAGACATACTCCTGTG
ATATTCCTCAGTGCTAAAAGCGAAGAGTTTGACAAGGTTCTTGGGTTGGAACTTGGTGCTGACGATTATATTACGAAGCC
ATTCAGTGTCAGGGAGGCTCTAGCGAGGATAAGGGCTATATTCAGAAGGATCCAGCAGAGCGTTCAGGCAAAGGAAGAGA
GACCTAAGAAGATAACGGCAAGAGACCTTGAAATAGACACTGAGAAGTATGAAGTGAGAGTCAGAGGGAAACTGGTCAAT
TTAACACCTCTTGAGTTTGAGCTCCTTAGATTCCTCGCTGAGAATGAAGGTAAGGTTTTCAGCAGGGATGTCCTTCTCGA
CAAACTCTGGGGTTACGATTACTATGGTGACACCAGAACTGTTGATGTTCATATAAGACGCCTGAGAACGAAGATCGAAG
AGGATCCTTCCAATCCTAAATATATCATAACAGTGAGGGGTAAAGGATACAAATTCAGAGACCCTGGAAAGGAAGACTGA

Upstream 100 bases:

>100_bases
AAGAGAATTTTTGTTGTGGATAAATAACAATAAAAAAGGCAGAGAATTTCTCTATAAGTATGCAGAAAGGATAAACCTTC
AAAGAAAGGAGTGAGAAAGA

Downstream 100 bases:

>100_bases
TTTTTGTTGACGGTATTTGTTATAATTCTGGCAGCGCTTTCCGCGCTGCTAGTTTATCTTCTGTACCGGACTAAAGTGGT
GTATGTCAGGTATGAAAAAA

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MAKKNILVIDDEPSIVELLSFNLKKEGYDVLKAYDAEEALKIVEDNDVDMFIVDIMLPGMDGFELVRNLRSTEKHRHTPV
IFLSAKSEEFDKVLGLELGADDYITKPFSVREALARIRAIFRRIQQSVQAKEERPKKITARDLEIDTEKYEVRVRGKLVN
LTPLEFELLRFLAENEGKVFSRDVLLDKLWGYDYYGDTRTVDVHIRRLRTKIEEDPSNPKYIITVRGKGYKFRDPGKED

Sequences:

>Translated_239_residues
MAKKNILVIDDEPSIVELLSFNLKKEGYDVLKAYDAEEALKIVEDNDVDMFIVDIMLPGMDGFELVRNLRSTEKHRHTPV
IFLSAKSEEFDKVLGLELGADDYITKPFSVREALARIRAIFRRIQQSVQAKEERPKKITARDLEIDTEKYEVRVRGKLVN
LTPLEFELLRFLAENEGKVFSRDVLLDKLWGYDYYGDTRTVDVHIRRLRTKIEEDPSNPKYIITVRGKGYKFRDPGKED
>Mature_238_residues
AKKNILVIDDEPSIVELLSFNLKKEGYDVLKAYDAEEALKIVEDNDVDMFIVDIMLPGMDGFELVRNLRSTEKHRHTPVI
FLSAKSEEFDKVLGLELGADDYITKPFSVREALARIRAIFRRIQQSVQAKEERPKKITARDLEIDTEKYEVRVRGKLVNL
TPLEFELLRFLAENEGKVFSRDVLLDKLWGYDYYGDTRTVDVHIRRLRTKIEEDPSNPKYIITVRGKGYKFRDPGKED

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=40.948275862069, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=39.0350877192982, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=37.719298245614, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=38.3259911894273, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=37.7118644067797, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=35.9649122807018, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=36.5217391304348, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1790860, Length=236, Percent_Identity=36.864406779661, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=38.695652173913, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=34.6491228070175, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=34.3612334801762, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=31.6017316017316, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=31.7180616740088, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=32.3404255319149, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=35.1351351351351, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=29.7709923664122, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788713, Length=149, Percent_Identity=32.8859060402685, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27828; Mature: 27697

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKNILVIDDEPSIVELLSFNLKKEGYDVLKAYDAEEALKIVEDNDVDMFIVDIMLPGM
CCCCCEEEECCCCCHHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCCEEEEEEECCCC
DGFELVRNLRSTEKHRHTPVIFLSAKSEEFDKVLGLELGADDYITKPFSVREALARIRAI
CHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHH
FRRIQQSVQAKEERPKKITARDLEIDTEKYEVRVRGKLVNLTPLEFELLRFLAENEGKVF
HHHHHHHHHHHHCCCCCCEECCEEECCCEEEEEEEEEEEECCCHHHHHHHHHHCCCCCEE
SRDVLLDKLWGYDYYGDTRTVDVHIRRLRTKIEEDPSNPKYIITVRGKGYKFRDPGKED
HHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCEECCCCCCCC
>Mature Secondary Structure 
AKKNILVIDDEPSIVELLSFNLKKEGYDVLKAYDAEEALKIVEDNDVDMFIVDIMLPGM
CCCCEEEECCCCCHHHHHHHCCCCCCHHHHHHCCHHHHHHHHCCCCCCEEEEEEECCCC
DGFELVRNLRSTEKHRHTPVIFLSAKSEEFDKVLGLELGADDYITKPFSVREALARIRAI
CHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHH
FRRIQQSVQAKEERPKKITARDLEIDTEKYEVRVRGKLVNLTPLEFELLRFLAENEGKVF
HHHHHHHHHHHHCCCCCCEECCEEECCCEEEEEEEEEEEECCCHHHHHHHHHHCCCCCEE
SRDVLLDKLWGYDYYGDTRTVDVHIRRLRTKIEEDPSNPKYIITVRGKGYKFRDPGKED
HHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA