BacMap

Definition	Kosmotoga olearia TBF 19.5.1, complete genome.
Accession	NC_012785
Length	2,302,126

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The map label for this gene is ftsH

Identifier: 239617940

GI number: 239617940

Start: 1680219

End: 1682156

Strand: Direct

Name: ftsH

Synonym: Kole_1568

Alternate gene names: 239617940

Gene position: 1680219-1682156 (Clockwise)

Preceding gene: 239617939

Following gene: 239617941

Centisome position: 72.99

GC content: 44.99

Gene sequence:

>1938_bases
GTGGATCAAAGGCCTAAGTTTGGCATGATTCTATTCTATATCGTGTTGGGAGTCTTCTTAATGGTTGCTCTTAGAGGGCT
ATATACTACTGACACAAATTTGTCAGTACCTTACAATCGTTTCCTTGAAGATGTGAATGATAAGAAAATTATTAAGATAG
TTATTTATGATGATGGGAGAATCGTTTATACAACCAGTGAAAGTTCGAAACGTTCTTTAGAAACCAAGGTTTCTCCCCAA
ACGCTTTCGACAGACAGGTTTCAGAACTATATAGACCAGCTGGTTACCGATGGTGTCAATGTTGTTTACGAGAAAGGGAA
TGATTCTCTTTTCTGGGTTAATCTGCTTGGCACCATTATCCCGTTGGCGATCATAGTGTTTATATGGTTTTTCGCGATGC
GATCATTATCTGGAAGGAATTCTCAGGCTTTTACTTTCACAAAGAGTCCCGCGAAAAAATATCTTTCAAATGATAAGAAC
GTTACCTTCAAAGATGTAGCTGGAGTGGATGAGGCTATAGAGGAACTTCAGGACGCCGTTAATTACCTTAAAAATCCGAA
CGCTTTTTCACAAACCGGTGCACGTATGCCCAAAGGTATACTTTTGGTTGGGCCTCCTGGAACCGGTAAAACACTTTTGG
CAAGGGCGGTTGCAGGAGAAGCTAATGTCCCATTCTTCTACATAAGTGGTTCCGATTTCGTTGAGCTTTTCGTCGGTGTT
GGTGCAGCCAGGGTCCGTGACCTTTTTTCACAGGCAAAAGCAAGTGCACCCTCAATCATATTCATAGACGAAATAGATGC
TGTTGGAAGGCACAGAGGAGCGGGTCTCGGTGGTGGACACGACGAAAGAGAACAAACCTTGAACCAGATACTGGTTGAGA
TGGACGGATTTGACGCGAAAACAGGTGTTATCGTGATGGCAGCCACCAACAGGCCTGATATCCTTGACCATGCTCTGCTC
AGACCGGGACGTTTCGATAAGAAAATAACCGTTGATCCACCAGATGTGAAAGGCAGAGCAGAGATTCTAAAGATACACAT
GAGAGGAAAACCTGTTGATCCCGACGTTGATGTCTGGTTGCTTGCAAGGAGGACTCCAGGGTTTGTTGGTGCGGATCTGG
AAAACCTAGTCAATGAAGCTGCCATACTTGCAGCCAGGAGAAAGAAAAAGATTATTGGGATGAAAGAACTCGAAGAAGCC
ATAGATCGGGTTATAGCTGGCCCGGCAAGGAAGTCCAGAATAATGAACCCAAAGGAGAAAAAGATTGTGGCTTATCACGA
GCTCGGACACGCGATCGTGGGGCTCGCGCTTCCCAACGCTTATCCAGTTCATAAAGTTACGGTAATTCCGAGAGGAAGTG
CTTCCCTTGGGTTCACCGAGAGTTTGCCTTCGGAAGATAGATACCTTGTCTCCCGTTCCGAGATGCTTGACAATCTGGCG
CAGATTCTTGGTGGCAGAGCAGCTGAAGAGATTGTATTCGGTGAGATCACCACCGGGGCAGCCAACGATCTTGAACGGGC
TACCCAGATGGCGCGAACGATGGTCTGTCAGTTAGGGATGAGCGATAGGCTCGGTCCAATAGCCTGGGGGAAGGAAGAAG
GAGAGGTATTCCTCGGGCGCGAGTTAACACGAATGCGAAATTACAGTGAAGAGATAGCCAGTGAAATAGACAACGAGGTA
AAAAAGATAGTTATAGAGGCACATGAAAGAGCCAGAAAATTGGTTGAAAAGTTCAGAGATAAACTTGATAAAGCGGCAGA
ATATCTCATAGAAAAAGAAACGATAACGGGCAAAGAACTTGCAGAAATAGTTGGATTAGCAGAGAGCGGGAATTATTACC
GTGATCCTCTTGCTGAAACGAAGGGATCGAAGAGAAAAGTAAGTGCTGTAAGCACCAATGAAGAAGCAAAGGAAGGCAAT
GAAGATGAAAAGAATTGA

Upstream 100 bases:

>100_bases
ACAATTTTATGGGTACCGGGAATTAGAGCCGCTGAGCAGTGCAGGGTGTCCGATTCCGAAGACGGATACGCCCTTTTTAG
ATTTGAAAGGAGGTAATTTG

Downstream 100 bases:

>100_bases
AGAACACCAGGAAATTTTTGTTGTAGATACAAACAACCCTGAGTTGCGCTGGGAGGAGAATCCAGCCGGTGGGGCGTTGA
ATCTCATATCAAGCAGTGGG

Product: ATP-dependent metalloprotease FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MDQRPKFGMILFYIVLGVFLMVALRGLYTTDTNLSVPYNRFLEDVNDKKIIKIVIYDDGRIVYTTSESSKRSLETKVSPQ
TLSTDRFQNYIDQLVTDGVNVVYEKGNDSLFWVNLLGTIIPLAIIVFIWFFAMRSLSGRNSQAFTFTKSPAKKYLSNDKN
VTFKDVAGVDEAIEELQDAVNYLKNPNAFSQTGARMPKGILLVGPPGTGKTLLARAVAGEANVPFFYISGSDFVELFVGV
GAARVRDLFSQAKASAPSIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQILVEMDGFDAKTGVIVMAATNRPDILDHALL
RPGRFDKKITVDPPDVKGRAEILKIHMRGKPVDPDVDVWLLARRTPGFVGADLENLVNEAAILAARRKKKIIGMKELEEA
IDRVIAGPARKSRIMNPKEKKIVAYHELGHAIVGLALPNAYPVHKVTVIPRGSASLGFTESLPSEDRYLVSRSEMLDNLA
QILGGRAAEEIVFGEITTGAANDLERATQMARTMVCQLGMSDRLGPIAWGKEEGEVFLGRELTRMRNYSEEIASEIDNEV
KKIVIEAHERARKLVEKFRDKLDKAAEYLIEKETITGKELAEIVGLAESGNYYRDPLAETKGSKRKVSAVSTNEEAKEGN
EDEKN

Sequences:

>Translated_645_residues
MDQRPKFGMILFYIVLGVFLMVALRGLYTTDTNLSVPYNRFLEDVNDKKIIKIVIYDDGRIVYTTSESSKRSLETKVSPQ
TLSTDRFQNYIDQLVTDGVNVVYEKGNDSLFWVNLLGTIIPLAIIVFIWFFAMRSLSGRNSQAFTFTKSPAKKYLSNDKN
VTFKDVAGVDEAIEELQDAVNYLKNPNAFSQTGARMPKGILLVGPPGTGKTLLARAVAGEANVPFFYISGSDFVELFVGV
GAARVRDLFSQAKASAPSIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQILVEMDGFDAKTGVIVMAATNRPDILDHALL
RPGRFDKKITVDPPDVKGRAEILKIHMRGKPVDPDVDVWLLARRTPGFVGADLENLVNEAAILAARRKKKIIGMKELEEA
IDRVIAGPARKSRIMNPKEKKIVAYHELGHAIVGLALPNAYPVHKVTVIPRGSASLGFTESLPSEDRYLVSRSEMLDNLA
QILGGRAAEEIVFGEITTGAANDLERATQMARTMVCQLGMSDRLGPIAWGKEEGEVFLGRELTRMRNYSEEIASEIDNEV
KKIVIEAHERARKLVEKFRDKLDKAAEYLIEKETITGKELAEIVGLAESGNYYRDPLAETKGSKRKVSAVSTNEEAKEGN
EDEKN
>Mature_645_residues
MDQRPKFGMILFYIVLGVFLMVALRGLYTTDTNLSVPYNRFLEDVNDKKIIKIVIYDDGRIVYTTSESSKRSLETKVSPQ
TLSTDRFQNYIDQLVTDGVNVVYEKGNDSLFWVNLLGTIIPLAIIVFIWFFAMRSLSGRNSQAFTFTKSPAKKYLSNDKN
VTFKDVAGVDEAIEELQDAVNYLKNPNAFSQTGARMPKGILLVGPPGTGKTLLARAVAGEANVPFFYISGSDFVELFVGV
GAARVRDLFSQAKASAPSIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQILVEMDGFDAKTGVIVMAATNRPDILDHALL
RPGRFDKKITVDPPDVKGRAEILKIHMRGKPVDPDVDVWLLARRTPGFVGADLENLVNEAAILAARRKKKIIGMKELEEA
IDRVIAGPARKSRIMNPKEKKIVAYHELGHAIVGLALPNAYPVHKVTVIPRGSASLGFTESLPSEDRYLVSRSEMLDNLA
QILGGRAAEEIVFGEITTGAANDLERATQMARTMVCQLGMSDRLGPIAWGKEEGEVFLGRELTRMRNYSEEIASEIDNEV
KKIVIEAHERARKLVEKFRDKLDKAAEYLIEKETITGKELAEIVGLAESGNYYRDPLAETKGSKRKVSAVSTNEEAKEGN
EDEKN

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family

Homologues:

Organism=Homo sapiens, GI300192933, Length=623, Percent_Identity=41.8940609951846, Blast_Score=466, Evalue=1e-131,
Organism=Homo sapiens, GI7657689, Length=499, Percent_Identity=45.2905811623246, Blast_Score=414, Evalue=1e-115,
Organism=Homo sapiens, GI21327685, Length=499, Percent_Identity=45.2905811623246, Blast_Score=413, Evalue=1e-115,
Organism=Homo sapiens, GI4507173, Length=549, Percent_Identity=40.8014571948998, Blast_Score=401, Evalue=1e-112,
Organism=Homo sapiens, GI4506209, Length=254, Percent_Identity=44.0944881889764, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI24497435, Length=252, Percent_Identity=42.0634920634921, Blast_Score=209, Evalue=8e-54,
Organism=Homo sapiens, GI21361144, Length=226, Percent_Identity=46.0176991150442, Blast_Score=199, Evalue=8e-51,
Organism=Homo sapiens, GI195539395, Length=246, Percent_Identity=41.0569105691057, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI6005942, Length=226, Percent_Identity=43.3628318584071, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI45643123, Length=273, Percent_Identity=40.2930402930403, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI157671927, Length=245, Percent_Identity=40.8163265306122, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI45643125, Length=273, Percent_Identity=40.2930402930403, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI24430151, Length=245, Percent_Identity=38.3673469387755, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI229577436, Length=250, Percent_Identity=41.6, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI40806173, Length=232, Percent_Identity=44.3965517241379, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI5729991, Length=254, Percent_Identity=38.9763779527559, Blast_Score=176, Evalue=9e-44,
Organism=Homo sapiens, GI89064750, Length=254, Percent_Identity=38.9763779527559, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI24430155, Length=254, Percent_Identity=38.9763779527559, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI4505725, Length=231, Percent_Identity=38.5281385281385, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI153792536, Length=238, Percent_Identity=39.9159663865546, Blast_Score=163, Evalue=6e-40,
Organism=Homo sapiens, GI24497618, Length=239, Percent_Identity=40.1673640167364, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI14149767, Length=243, Percent_Identity=39.0946502057613, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI62177112, Length=243, Percent_Identity=39.0946502057613, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI5901990, Length=243, Percent_Identity=39.5061728395062, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI7019569, Length=266, Percent_Identity=36.8421052631579, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI156564401, Length=262, Percent_Identity=37.7862595419847, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI194018488, Length=275, Percent_Identity=37.4545454545455, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI31377644, Length=233, Percent_Identity=38.6266094420601, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI226371754, Length=243, Percent_Identity=38.2716049382716, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI17865802, Length=292, Percent_Identity=36.986301369863, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI310125280, Length=220, Percent_Identity=41.3636363636364, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI310125282, Length=262, Percent_Identity=37.4045801526718, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI40806170, Length=232, Percent_Identity=41.8103448275862, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI11875211, Length=232, Percent_Identity=41.8103448275862, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI31742536, Length=227, Percent_Identity=34.3612334801762, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI112789543, Length=227, Percent_Identity=34.3612334801762, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI64084766, Length=226, Percent_Identity=30.5309734513274, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI116292174, Length=260, Percent_Identity=29.2307692307692, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI1789568, Length=599, Percent_Identity=48.2470784641068, Blast_Score=565, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI71994521, Length=464, Percent_Identity=50.2155172413793, Blast_Score=433, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17554264, Length=478, Percent_Identity=45.397489539749, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI115534323, Length=461, Percent_Identity=45.119305856833, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17554786, Length=252, Percent_Identity=43.2539682539683, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17563248, Length=254, Percent_Identity=43.7007874015748, Blast_Score=211, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI25144281, Length=252, Percent_Identity=43.2539682539683, Blast_Score=210, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI25144278, Length=252, Percent_Identity=43.2539682539683, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17532375, Length=228, Percent_Identity=41.2280701754386, Blast_Score=198, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI71987364, Length=246, Percent_Identity=41.0569105691057, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI71987372, Length=246, Percent_Identity=41.0569105691057, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17505546, Length=245, Percent_Identity=41.2244897959184, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17508701, Length=245, Percent_Identity=42.4489795918367, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17563250, Length=245, Percent_Identity=40, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17531535, Length=229, Percent_Identity=42.3580786026201, Blast_Score=184, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI17508053, Length=259, Percent_Identity=40.1544401544402, Blast_Score=179, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17554784, Length=247, Percent_Identity=38.8663967611336, Blast_Score=168, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17537217, Length=259, Percent_Identity=37.8378378378378, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI193206116, Length=250, Percent_Identity=39.2, Blast_Score=162, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI133931034, Length=250, Percent_Identity=39.2, Blast_Score=161, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI193206114, Length=250, Percent_Identity=39.2, Blast_Score=161, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI25153574, Length=264, Percent_Identity=35.2272727272727, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=47.2727272727273, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=47.2727272727273, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI193209502, Length=263, Percent_Identity=34.9809885931559, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI133901662, Length=306, Percent_Identity=33.6601307189542, Blast_Score=142, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI133901658, Length=306, Percent_Identity=33.6601307189542, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI86561515, Length=272, Percent_Identity=36.7647058823529, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17562804, Length=232, Percent_Identity=37.0689655172414, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI32563584, Length=265, Percent_Identity=39.2452830188679, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17508421, Length=265, Percent_Identity=39.2452830188679, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI25146157, Length=237, Percent_Identity=40.5063291139241, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17541224, Length=241, Percent_Identity=34.8547717842324, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17541226, Length=241, Percent_Identity=34.8547717842324, Blast_Score=122, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17560432, Length=233, Percent_Identity=36.9098712446352, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17570511, Length=86, Percent_Identity=41.8604651162791, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323736, Length=577, Percent_Identity=42.9809358752166, Blast_Score=459, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6320854, Length=560, Percent_Identity=44.8214285714286, Blast_Score=458, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6325281, Length=447, Percent_Identity=45.1901565995526, Blast_Score=393, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6322704, Length=249, Percent_Identity=43.7751004016064, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6321390, Length=245, Percent_Identity=41.6326530612245, Blast_Score=206, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6324691, Length=253, Percent_Identity=43.8735177865613, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6320077, Length=228, Percent_Identity=42.9824561403509, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6324833, Length=245, Percent_Identity=40.8163265306122, Blast_Score=187, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6320197, Length=259, Percent_Identity=37.0656370656371, Blast_Score=184, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6320602, Length=245, Percent_Identity=40.4081632653061, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6322994, Length=234, Percent_Identity=38.4615384615385, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324000, Length=241, Percent_Identity=39.8340248962656, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6321709, Length=261, Percent_Identity=37.9310344827586, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6323429, Length=255, Percent_Identity=38.4313725490196, Blast_Score=163, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6322651, Length=264, Percent_Identity=34.469696969697, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6325431, Length=247, Percent_Identity=38.8663967611336, Blast_Score=144, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6321465, Length=240, Percent_Identity=35.8333333333333, Blast_Score=133, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6325183, Length=243, Percent_Identity=36.6255144032922, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319554, Length=220, Percent_Identity=36.3636363636364, Blast_Score=131, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6320887, Length=252, Percent_Identity=34.5238095238095, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6320583, Length=198, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28574878, Length=541, Percent_Identity=44.362292051756, Blast_Score=449, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24665814, Length=464, Percent_Identity=49.3534482758621, Blast_Score=449, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24639391, Length=522, Percent_Identity=43.4865900383142, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24658770, Length=496, Percent_Identity=45.7661290322581, Blast_Score=408, Evalue=1e-114,
Organism=Drosophila melanogaster, GI17137738, Length=254, Percent_Identity=43.3070866141732, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI19920408, Length=252, Percent_Identity=41.6666666666667, Blast_Score=206, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24651451, Length=252, Percent_Identity=41.2698412698413, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17137560, Length=229, Percent_Identity=41.4847161572052, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI161076488, Length=229, Percent_Identity=41.4847161572052, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI161076486, Length=229, Percent_Identity=41.4847161572052, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI45554047, Length=236, Percent_Identity=44.9152542372881, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI17738151, Length=245, Percent_Identity=42.8571428571429, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24640100, Length=246, Percent_Identity=40.2439024390244, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24649446, Length=245, Percent_Identity=38.7755102040816, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24663015, Length=256, Percent_Identity=38.28125, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI19921202, Length=239, Percent_Identity=39.7489539748954, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24652279, Length=190, Percent_Identity=43.6842105263158, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281365776, Length=232, Percent_Identity=41.3793103448276, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24660075, Length=232, Percent_Identity=41.3793103448276, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281361487, Length=241, Percent_Identity=39.0041493775934, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI45552965, Length=232, Percent_Identity=41.3793103448276, Blast_Score=176, Evalue=5e-44,
Organism=Drosophila melanogaster, GI18860063, Length=241, Percent_Identity=39.4190871369295, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24656825, Length=248, Percent_Identity=39.1129032258064, Blast_Score=162, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24656820, Length=248, Percent_Identity=39.1129032258064, Blast_Score=162, Evalue=8e-40,
Organism=Drosophila melanogaster, GI281363136, Length=234, Percent_Identity=38.8888888888889, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI78707192, Length=234, Percent_Identity=38.8888888888889, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24644145, Length=241, Percent_Identity=40.2489626556017, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281360146, Length=242, Percent_Identity=36.7768595041322, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI281360142, Length=242, Percent_Identity=36.7768595041322, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI281360138, Length=242, Percent_Identity=36.7768595041322, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI21357333, Length=242, Percent_Identity=36.7768595041322, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI281360144, Length=242, Percent_Identity=36.7768595041322, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI281360140, Length=242, Percent_Identity=36.7768595041322, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI281360136, Length=242, Percent_Identity=36.7768595041322, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24644411, Length=242, Percent_Identity=36.7768595041322, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI18859657, Length=232, Percent_Identity=41.3793103448276, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI21355121, Length=271, Percent_Identity=30.2583025830258, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17864540, Length=218, Percent_Identity=39.4495412844037, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571849, Length=229, Percent_Identity=40.6113537117904, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571847, Length=229, Percent_Identity=40.6113537117904, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI20129529, Length=236, Percent_Identity=35.5932203389831, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI20129423, Length=234, Percent_Identity=35.042735042735, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28573010, Length=218, Percent_Identity=39.4495412844037, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24581396, Length=236, Percent_Identity=37.2881355932203, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24639486, Length=289, Percent_Identity=31.1418685121107, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSH_KOSOT (C5CES8)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941262.1
- ProteinModelPortal:   C5CES8
- GeneID:   7968646
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_1568
- ProtClustDB:   CLSK875225
- GO:   GO:0006508
- HAMAP:   MF_01458
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642
- SMART:   SM00382
- TIGRFAMs:   TIGR01241

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41

EC number: 3.4.24.-

Molecular weight: Translated: 71386; Mature: 71386

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00674 AAA; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 427-427

Signals:

None

Transmembrane regions:

HASH(0x29d8ca8c)-; HASH(0x299f14d0)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQRPKFGMILFYIVLGVFLMVALRGLYTTDTNLSVPYNRFLEDVNDKKIIKIVIYDDGR
CCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHCCCCCEEEEEEEEECCE
IVYTTSESSKRSLETKVSPQTLSTDRFQNYIDQLVTDGVNVVYEKGNDSLFWVNLLGTII
EEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHHH
PLAIIVFIWFFAMRSLSGRNSQAFTFTKSPAKKYLSNDKNVTFKDVAGVDEAIEELQDAV
HHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHH
NYLKNPNAFSQTGARMPKGILLVGPPGTGKTLLARAVAGEANVPFFYISGSDFVELFVGV
HHHCCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHC
GAARVRDLFSQAKASAPSIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQILVEMDGFDAK
CHHHHHHHHHHHHCCCCCEEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
TGVIVMAATNRPDILDHALLRPGRFDKKITVDPPDVKGRAEILKIHMRGKPVDPDVDVWL
CCEEEEEECCCCCHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEE
LARRTPGFVGADLENLVNEAAILAARRKKKIIGMKELEEAIDRVIAGPARKSRIMNPKEK
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHCCCCCHH
KIVAYHELGHAIVGLALPNAYPVHKVTVIPRGSASLGFTESLPSEDRYLVSRSEMLDNLA
HEEHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QILGGRAAEEIVFGEITTGAANDLERATQMARTMVCQLGMSDRLGPIAWGKEEGEVFLGR
HHHCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHH
ELTRMRNYSEEIASEIDNEVKKIVIEAHERARKLVEKFRDKLDKAAEYLIEKETITGKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AEIVGLAESGNYYRDPLAETKGSKRKVSAVSTNEEAKEGNEDEKN
HHHHHHHCCCCCCCCCHHHCCCCCCEEEEECCCCHHHCCCCCCCH
>Mature Secondary Structure
MDQRPKFGMILFYIVLGVFLMVALRGLYTTDTNLSVPYNRFLEDVNDKKIIKIVIYDDGR
CCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHCCCCCEEEEEEEEECCE
IVYTTSESSKRSLETKVSPQTLSTDRFQNYIDQLVTDGVNVVYEKGNDSLFWVNLLGTII
EEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHHH
PLAIIVFIWFFAMRSLSGRNSQAFTFTKSPAKKYLSNDKNVTFKDVAGVDEAIEELQDAV
HHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHH
NYLKNPNAFSQTGARMPKGILLVGPPGTGKTLLARAVAGEANVPFFYISGSDFVELFVGV
HHHCCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHC
GAARVRDLFSQAKASAPSIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQILVEMDGFDAK
CHHHHHHHHHHHHCCCCCEEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
TGVIVMAATNRPDILDHALLRPGRFDKKITVDPPDVKGRAEILKIHMRGKPVDPDVDVWL
CCEEEEEECCCCCHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEE
LARRTPGFVGADLENLVNEAAILAARRKKKIIGMKELEEAIDRVIAGPARKSRIMNPKEK
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHCCCCCHH
KIVAYHELGHAIVGLALPNAYPVHKVTVIPRGSASLGFTESLPSEDRYLVSRSEMLDNLA
HEEHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QILGGRAAEEIVFGEITTGAANDLERATQMARTMVCQLGMSDRLGPIAWGKEEGEVFLGR
HHHCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHH
ELTRMRNYSEEIASEIDNEVKKIVIEAHERARKLVEKFRDKLDKAAEYLIEKETITGKEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AEIVGLAESGNYYRDPLAETKGSKRKVSAVSTNEEAKEGNEDEKN
HHHHHHHCCCCCCCCCHHHCCCCCCEEEEECCCCHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA