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The map label for this gene is dnaC [H]

Identifier: 239617887

GI number: 239617887

Start: 1625387

End: 1626742

Strand: Direct

Name: dnaC [H]

Synonym: Kole_1515

Alternate gene names: 239617887

Gene position: 1625387-1626742 (Clockwise)

Preceding gene: 239617886

Following gene: 239617888

Centisome position: 70.6

GC content: 44.91

Gene sequence:

>1356_bases
ATGAATCCGAAGATACCACCACATAGCAACGAAGCAGAGGAGGCAGTTATAGGTAGCATACTCATAGACCCTGATGTCAT
TCCAGATGTTATGGAGATCCTCAGGAGCAATGATTTTTATTCCATCAAACATCGCACCGTGTTTGCCGCAATAGAGGATC
TCTTTGATCATGGAAATCCTGTGGATGTCGTCTCTATCATTGAAAAATTAAGGAGTCAGGGTTCTCTAGAAGATATTGGT
GGAGAGGTTGAAATTATGAAGCTTGCCGATATCGTACCCACCGCAGCGAACGTTGTATATTATGCAAAGATAGTGAAGGA
AAAGGCGTTGATGCGCGCCTTGATAAATGCTGGAAGTAAGATTGTAGAGGAAGCGTATCAAGCGGAGGATGTGGATCAGC
TACTTGATGATGCTGAAAAGCGAATATTCAGGATAACGGAAAGTCATACATCCCGGACCTATGAAAACCTTGGAAAGGTT
ATGCATTCGGTTTTTGAGGATCTGGAAAAACTTAAAAATACAGCGGGAACGATAGAAGCTGGAGGCTTGATAACGGGGAT
TCCTACGGGATTCAGACAGCTTGACAAAATGACAACAGGTTTTCATCAATCTGATTTGATAATTATTGCGGCGAGGCCTT
CGATGGGAAAAACCGCTTTTGCGTTGAATATCACGAAAAATATGGCGTTGAAGCACGACATTCCCGTGGCTTTCTTCTGT
CTTGAAATGACAAAGGAGCAGCTCGCCCAGAGGCTCCTGTGTTCGGAAGCCAGCGTCGATCTTCACAAGGTGAGGACGGG
TTTTCTCAGCAAGCAGGAGTGGGAGCTCCTTACGAATGCTGCGTCGCGTTTGTATAAATCAAAGATAGTGGTAGATGATG
AACCATCCCTCGATCCCAGAACTCTAAGGGCCAAGGCAAGGAGAATTAAATCGGAATACGGCGTACAGGTTATCTTTATA
GATTATCTTCAGCTTATGCACCTGAAGGGCCGTTCTGAAAACAGGCAACAGGAAATTTCAGAAATCTCCCGTTCTTTAAA
GCTTCTGGCAAGAGAGCTCAATGTGGCGGTTGTTGCATTGTCGCAGCTTTCCCGTGCTGTCGAGCAGCGTGAAAATAAGA
GACCGCGATTGAGCGATCTTCGAGAATCGGGGGCCATCGAGCAGGATGCAGATATGGTTATGTTTCTCTATCGTGATGAC
TATTACAAGAGCAAATCTGAGGTTCAGGATCAACCGCATGAGTCGGAGGTTATAATAGGAAAACAGAGAAATGGTCCTAT
AGGTACGGTGAAGCTGATATTCAATCCGAAAGTCGCGACATTTTTCGATGAAGTACCGAGTGAGTTTGTTGAGTGA

Upstream 100 bases:

>100_bases
TAAAAGGCGGAGCTGGTAAAACCAGAGGGCAGTTTGTCTATTCGAAAGAGCTTGATGAGCTTATTGAATTTACCCTTCAC
TGGATGAAAGGAGAGAAATC

Downstream 100 bases:

>100_bases
GACGAGAGTCGCTACGCGGCTGAAGTGCTGGGCTACGCCCAGGAGGCTCACGACGTTGACGCTTGCGAGGCTGAGGCTTG
CGGACGCTGATAAAAAAACG

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MNPKIPPHSNEAEEAVIGSILIDPDVIPDVMEILRSNDFYSIKHRTVFAAIEDLFDHGNPVDVVSIIEKLRSQGSLEDIG
GEVEIMKLADIVPTAANVVYYAKIVKEKALMRALINAGSKIVEEAYQAEDVDQLLDDAEKRIFRITESHTSRTYENLGKV
MHSVFEDLEKLKNTAGTIEAGGLITGIPTGFRQLDKMTTGFHQSDLIIIAARPSMGKTAFALNITKNMALKHDIPVAFFC
LEMTKEQLAQRLLCSEASVDLHKVRTGFLSKQEWELLTNAASRLYKSKIVVDDEPSLDPRTLRAKARRIKSEYGVQVIFI
DYLQLMHLKGRSENRQQEISEISRSLKLLARELNVAVVALSQLSRAVEQRENKRPRLSDLRESGAIEQDADMVMFLYRDD
YYKSKSEVQDQPHESEVIIGKQRNGPIGTVKLIFNPKVATFFDEVPSEFVE

Sequences:

>Translated_451_residues
MNPKIPPHSNEAEEAVIGSILIDPDVIPDVMEILRSNDFYSIKHRTVFAAIEDLFDHGNPVDVVSIIEKLRSQGSLEDIG
GEVEIMKLADIVPTAANVVYYAKIVKEKALMRALINAGSKIVEEAYQAEDVDQLLDDAEKRIFRITESHTSRTYENLGKV
MHSVFEDLEKLKNTAGTIEAGGLITGIPTGFRQLDKMTTGFHQSDLIIIAARPSMGKTAFALNITKNMALKHDIPVAFFC
LEMTKEQLAQRLLCSEASVDLHKVRTGFLSKQEWELLTNAASRLYKSKIVVDDEPSLDPRTLRAKARRIKSEYGVQVIFI
DYLQLMHLKGRSENRQQEISEISRSLKLLARELNVAVVALSQLSRAVEQRENKRPRLSDLRESGAIEQDADMVMFLYRDD
YYKSKSEVQDQPHESEVIIGKQRNGPIGTVKLIFNPKVATFFDEVPSEFVE
>Mature_451_residues
MNPKIPPHSNEAEEAVIGSILIDPDVIPDVMEILRSNDFYSIKHRTVFAAIEDLFDHGNPVDVVSIIEKLRSQGSLEDIG
GEVEIMKLADIVPTAANVVYYAKIVKEKALMRALINAGSKIVEEAYQAEDVDQLLDDAEKRIFRITESHTSRTYENLGKV
MHSVFEDLEKLKNTAGTIEAGGLITGIPTGFRQLDKMTTGFHQSDLIIIAARPSMGKTAFALNITKNMALKHDIPVAFFC
LEMTKEQLAQRLLCSEASVDLHKVRTGFLSKQEWELLTNAASRLYKSKIVVDDEPSLDPRTLRAKARRIKSEYGVQVIFI
DYLQLMHLKGRSENRQQEISEISRSLKLLARELNVAVVALSQLSRAVEQRENKRPRLSDLRESGAIEQDADMVMFLYRDD
YYKSKSEVQDQPHESEVIIGKQRNGPIGTVKLIFNPKVATFFDEVPSEFVE

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=444, Percent_Identity=45.045045045045, Blast_Score=379, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 50833; Mature: 50833

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPKIPPHSNEAEEAVIGSILIDPDVIPDVMEILRSNDFYSIKHRTVFAAIEDLFDHGNP
CCCCCCCCCCCHHHHHHHHHEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCC
VDVVSIIEKLRSQGSLEDIGGEVEIMKLADIVPTAANVVYYAKIVKEKALMRALINAGSK
HHHHHHHHHHHCCCCHHHCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
IVEEAYQAEDVDQLLDDAEKRIFRITESHTSRTYENLGKVMHSVFEDLEKLKNTAGTIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
GGLITGIPTGFRQLDKMTTGFHQSDLIIIAARPSMGKTAFALNITKNMALKHDIPVAFFC
CCEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEEHHCCCHHCCCCHHHHH
LEMTKEQLAQRLLCSEASVDLHKVRTGFLSKQEWELLTNAASRLYKSKIVVDDEPSLDPR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEECCCCCCCHH
TLRAKARRIKSEYGVQVIFIDYLQLMHLKGRSENRQQEISEISRSLKLLARELNVAVVAL
HHHHHHHHHHHHHCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLSRAVEQRENKRPRLSDLRESGAIEQDADMVMFLYRDDYYKSKSEVQDQPHESEVIIG
HHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEEEECCHHCCHHHHCCCCCCCCEEEE
KQRNGPIGTVKLIFNPKVATFFDEVPSEFVE
ECCCCCCEEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPKIPPHSNEAEEAVIGSILIDPDVIPDVMEILRSNDFYSIKHRTVFAAIEDLFDHGNP
CCCCCCCCCCCHHHHHHHHHEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCC
VDVVSIIEKLRSQGSLEDIGGEVEIMKLADIVPTAANVVYYAKIVKEKALMRALINAGSK
HHHHHHHHHHHCCCCHHHCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
IVEEAYQAEDVDQLLDDAEKRIFRITESHTSRTYENLGKVMHSVFEDLEKLKNTAGTIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
GGLITGIPTGFRQLDKMTTGFHQSDLIIIAARPSMGKTAFALNITKNMALKHDIPVAFFC
CCEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEEHHCCCHHCCCCHHHHH
LEMTKEQLAQRLLCSEASVDLHKVRTGFLSKQEWELLTNAASRLYKSKIVVDDEPSLDPR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEECCCCCCCHH
TLRAKARRIKSEYGVQVIFIDYLQLMHLKGRSENRQQEISEISRSLKLLARELNVAVVAL
HHHHHHHHHHHHHCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLSRAVEQRENKRPRLSDLRESGAIEQDADMVMFLYRDDYYKSKSEVQDQPHESEVIIG
HHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEEEECCHHCCHHHHCCCCCCCCEEEE
KQRNGPIGTVKLIFNPKVATFFDEVPSEFVE
ECCCCCCEEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]