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The map label for this gene is argF [H]

Identifier: 239617807

GI number: 239617807

Start: 1528188

End: 1529129

Strand: Reverse

Name: argF [H]

Synonym: Kole_1433

Alternate gene names: 239617807

Gene position: 1529129-1528188 (Counterclockwise)

Preceding gene: 239617810

Following gene: 239617806

Centisome position: 66.42

GC content: 42.36

Gene sequence:

>942_bases
GTGGGAGTAAATCTTAAAGGAAAAAGCTTTCTCACTCTCTTGGATTTTAAACCGGATGAAATACGCTATCTCCTCGATAT
AGCCAGAGAAGTAAAAGCAGAAAAAAGAGCAGGTTTAACAACACAAAGATTTCTCGGGAAAACACTTGCCATAATCTTCG
AGAAAAGATCAACAAGAACGCGAACTGCTTTCGAAACGGCTTTCGGTGAAGAAGGCGGGCACCCGGTGTTTCTATCAAAA
GACGATATCCACCTCGGTGTCAAGGAAGATCTCGAAGACACCGCAAGGGTTCTCGGAAGAATGTTCGATGCAATAGCATT
CAGAGGATTTAAACAGAAAACTGTTGAAGGCCTTGCAAAATGGTCTGGAATACCTGTTTACAACGGTCTCACAGATCTCT
ACCACCCCACCCAGATACTCGCCGACTTCATGACAATAGAGGAATATTTCGGAAGCCTCAGAGGAAGAAAACTTGTCTTT
ATGGGAGATGCCAGAAACAATGTGGCAAATTCCCTTATGATTGGTTCTGCTAAAATGGGACTGCATTTTGTTGCTTGTGG
TCCAAAGGATCTCTGGCCTTCTGAGGAATTGGTAAAAAAATGCAGGGAGATTTCCGAAAGTACCAACGCTGTTATCGAAA
TAACCGACGATCCAGCTGAAGCGGTAAAGAACGCTGACGCTATCTATACAGATGTCTGGGCCTCAATGGGTGAAGAAGAC
AAACTTAAAGAAAGAATTGCTTTACTCAGACCTTATCAGGTAAACCAGGAATTGATGGAACTAACAGACAGAAAAGATAC
CATATTCCTCCATTGTTTGCCTGCTGTTAAAGGCAACGAGGTAACGAGAGATGTTATAGAAGGACCACAGTCAAGGGTAT
TCGAAGAAGCCGAAAACAGAAAGCATACTATTAAAGCTGTTATGATAGCAACTTTGTTGTAA

Upstream 100 bases:

>100_bases
TTAATCTAAGTTTACAGAAAGAGGTTAACATGATTGAAAGCATTTTTTTTAATGGGTATCATATAAGAAGAATACCACTT
TACTAAAGGAGGGAGTTTGT

Downstream 100 bases:

>100_bases
TGGGAGGTTTGGAGCATGAAAAAAGCAGTCGTAGCTATCGGCGGCAACGCACTGAACAAGCCCGGCGAAAAGCCAAGCGC
AGAGGCAATGAAGAAAAATC

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MGVNLKGKSFLTLLDFKPDEIRYLLDIAREVKAEKRAGLTTQRFLGKTLAIIFEKRSTRTRTAFETAFGEEGGHPVFLSK
DDIHLGVKEDLEDTARVLGRMFDAIAFRGFKQKTVEGLAKWSGIPVYNGLTDLYHPTQILADFMTIEEYFGSLRGRKLVF
MGDARNNVANSLMIGSAKMGLHFVACGPKDLWPSEELVKKCREISESTNAVIEITDDPAEAVKNADAIYTDVWASMGEED
KLKERIALLRPYQVNQELMELTDRKDTIFLHCLPAVKGNEVTRDVIEGPQSRVFEEAENRKHTIKAVMIATLL

Sequences:

>Translated_313_residues
MGVNLKGKSFLTLLDFKPDEIRYLLDIAREVKAEKRAGLTTQRFLGKTLAIIFEKRSTRTRTAFETAFGEEGGHPVFLSK
DDIHLGVKEDLEDTARVLGRMFDAIAFRGFKQKTVEGLAKWSGIPVYNGLTDLYHPTQILADFMTIEEYFGSLRGRKLVF
MGDARNNVANSLMIGSAKMGLHFVACGPKDLWPSEELVKKCREISESTNAVIEITDDPAEAVKNADAIYTDVWASMGEED
KLKERIALLRPYQVNQELMELTDRKDTIFLHCLPAVKGNEVTRDVIEGPQSRVFEEAENRKHTIKAVMIATLL
>Mature_312_residues
GVNLKGKSFLTLLDFKPDEIRYLLDIAREVKAEKRAGLTTQRFLGKTLAIIFEKRSTRTRTAFETAFGEEGGHPVFLSKD
DIHLGVKEDLEDTARVLGRMFDAIAFRGFKQKTVEGLAKWSGIPVYNGLTDLYHPTQILADFMTIEEYFGSLRGRKLVFM
GDARNNVANSLMIGSAKMGLHFVACGPKDLWPSEELVKKCREISESTNAVIEITDDPAEAVKNADAIYTDVWASMGEEDK
LKERIALLRPYQVNQELMELTDRKDTIFLHCLPAVKGNEVTRDVIEGPQSRVFEEAENRKHTIKAVMIATLL

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=311, Percent_Identity=45.016077170418, Blast_Score=268, Evalue=5e-72,
Organism=Homo sapiens, GI18105007, Length=320, Percent_Identity=25.3125, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786469, Length=330, Percent_Identity=47.8787878787879, Blast_Score=304, Evalue=4e-84,
Organism=Escherichia coli, GI1790703, Length=326, Percent_Identity=46.319018404908, Blast_Score=297, Evalue=7e-82,
Organism=Escherichia coli, GI48994908, Length=367, Percent_Identity=23.9782016348774, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI2367364, Length=313, Percent_Identity=29.073482428115, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193204318, Length=319, Percent_Identity=24.7648902821317, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322373, Length=308, Percent_Identity=35.3896103896104, Blast_Score=183, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6322331, Length=163, Percent_Identity=31.2883435582822, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642586, Length=309, Percent_Identity=27.1844660194175, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35247; Mature: 35116

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVNLKGKSFLTLLDFKPDEIRYLLDIAREVKAEKRAGLTTQRFLGKTLAIIFEKRSTRT
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCH
RTAFETAFGEEGGHPVFLSKDDIHLGVKEDLEDTARVLGRMFDAIAFRGFKQKTVEGLAK
HHHHHHHHCCCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
WSGIPVYNGLTDLYHPTQILADFMTIEEYFGSLRGRKLVFMGDARNNVANSLMIGSAKMG
HCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHEECCCCCC
LHFVACGPKDLWPSEELVKKCREISESTNAVIEITDDPAEAVKNADAIYTDVWASMGEED
EEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCHHHHHHHHHHCCCHH
KLKERIALLRPYQVNQELMELTDRKDTIFLHCLPAVKGNEVTRDVIEGPQSRVFEEAENR
HHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHH
KHTIKAVMIATLL
HHHHHHHHHHHCC
>Mature Secondary Structure 
GVNLKGKSFLTLLDFKPDEIRYLLDIAREVKAEKRAGLTTQRFLGKTLAIIFEKRSTRT
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCH
RTAFETAFGEEGGHPVFLSKDDIHLGVKEDLEDTARVLGRMFDAIAFRGFKQKTVEGLAK
HHHHHHHHCCCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
WSGIPVYNGLTDLYHPTQILADFMTIEEYFGSLRGRKLVFMGDARNNVANSLMIGSAKMG
HCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHEECCCCCC
LHFVACGPKDLWPSEELVKKCREISESTNAVIEITDDPAEAVKNADAIYTDVWASMGEED
EEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCHHHHHHHHHHCCCHH
KLKERIALLRPYQVNQELMELTDRKDTIFLHCLPAVKGNEVTRDVIEGPQSRVFEEAENR
HHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHH
KHTIKAVMIATLL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]