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The map label for this gene is yedV [H]

Identifier: 239617802

GI number: 239617802

Start: 1522599

End: 1523909

Strand: Reverse

Name: yedV [H]

Synonym: Kole_1428

Alternate gene names: 239617802

Gene position: 1523909-1522599 (Counterclockwise)

Preceding gene: 239617803

Following gene: 239617801

Centisome position: 66.2

GC content: 41.19

Gene sequence:

>1311_bases
GTGACTTTAAAAGCAAAGATCTCTCTGCTGTACCTTATTGCGTACGGTTCATCTTTGCTTTTTTTAGCCGCCTTTCTCTA
CGCTATCGTATACGATCTGAAATATCGAGAAGTCGACAATAGATTGCTGGCTTTTTATGGAAATATCGTTAGAGCATATA
CAATAGGAAATGCACCCCGTACAGGGCTGTTAAATCTACCGGGTAGTGAAGACCTGGGATTTGAAATCTACAAGAACGAT
AGGCTAATTGCTTCTTTTCGCATTAAAGGTGGTTTATTCAAAAACGTGGAAGCCCCAGGTACTGGATTCGGTAATTACGG
AAATTATCGCTACTATATCTCAGAAGAATCGGTCAACGGTGCTCAATACAAGTTCGTGGTTGCTCACAACCTGGCACCCA
TTAGGAATTTCCTCAAGAATCTCCTGATTGCGTTGATTGCAGGTTCCCTTTTTGTCGTGATATTGATAACACTTATAGGA
ATATTCATAACCAGAAAGCTACTCAATCCGATTGGAGAAATCGGAAAACAGCTTGAAGAGATCAGCCACACAGAAATAGA
CGGGAGAAGGGTGAATGTAAAAATCACCGGTTCAGAAATTGCGAGGCTTCAAAGCGAGGTTAACAAATCACTTAAAAGGC
TTGAACTACTCATCAAAGACGCCAAAGCTTTGTCCGCTAAAATCGCACACGAATTGAGAACCCCTCTTTCAGTTCTAAAA
TCAACTCTCCAATTAGCCTTAGCCCGCAATGATTCAGTTGACTCCATGAAACGCTCACTCAAAGAAAGCCTCCGCGAATT
AGATAACCTTATTCAAACCTCAAACGATCTATTACTAATCTCCAACATCGAAAAAGGGATCGTAAATAGGTTTAAACCTT
TCGACCTTTCGCAGACAGTTCTGGATGTGATAGAAAATCAAATGGTCCTTAATCCCGATAAACAATTCCACATAAACGTT
CCACCAGCTGTAACGTTCAACGGGGTAGAAACTCTGCTCGCACGTGCCGTTGCCAATCTCATAGAAAATGCCGTCAAATA
CTCCAGGGAAGGCACAATTGAAATAAAACTCAAATGCGATGACAAATCTATCATTATTGAAATTATTAATCCCGGTGAAG
AGATTCCTCCTCAAGAGCTTGAAAGAATCTTCGAGAACTTCTACAGGAGAAAGAACGTGGATAAAATAGAAGGTTACGGG
CTTGGCCTGTCGGTTGCCCGGGCTGTTGCAAAATTACACGGTGGCGATGTAATTTACAACTACAAAAATGGTCTAAACTG
TTTTGCGATCTACCTTCCGAGAATCAGTTAA

Upstream 100 bases:

>100_bases
TGCTCTACCTGAGAAAAAAGCTCAAACCTTTTGGTTACGACGAAAAAATAGAGACAGTTCATAACATCGGGTATAGACTC
AAGAAAGAAGATGATAAAAC

Downstream 100 bases:

>100_bases
AAGCCGGTAAGCCCGGCTTCGCCGGGGGTGAACCTCGAAAAACAGCAGGGTCAAGAGATGGCGCCTTAGGTTTAGGCAAC
ACCTATCCGGTTTCTCCCCG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTLKAKISLLYLIAYGSSLLFLAAFLYAIVYDLKYREVDNRLLAFYGNIVRAYTIGNAPRTGLLNLPGSEDLGFEIYKND
RLIASFRIKGGLFKNVEAPGTGFGNYGNYRYYISEESVNGAQYKFVVAHNLAPIRNFLKNLLIALIAGSLFVVILITLIG
IFITRKLLNPIGEIGKQLEEISHTEIDGRRVNVKITGSEIARLQSEVNKSLKRLELLIKDAKALSAKIAHELRTPLSVLK
STLQLALARNDSVDSMKRSLKESLRELDNLIQTSNDLLLISNIEKGIVNRFKPFDLSQTVLDVIENQMVLNPDKQFHINV
PPAVTFNGVETLLARAVANLIENAVKYSREGTIEIKLKCDDKSIIIEIINPGEEIPPQELERIFENFYRRKNVDKIEGYG
LGLSVARAVAKLHGGDVIYNYKNGLNCFAIYLPRIS

Sequences:

>Translated_436_residues
MTLKAKISLLYLIAYGSSLLFLAAFLYAIVYDLKYREVDNRLLAFYGNIVRAYTIGNAPRTGLLNLPGSEDLGFEIYKND
RLIASFRIKGGLFKNVEAPGTGFGNYGNYRYYISEESVNGAQYKFVVAHNLAPIRNFLKNLLIALIAGSLFVVILITLIG
IFITRKLLNPIGEIGKQLEEISHTEIDGRRVNVKITGSEIARLQSEVNKSLKRLELLIKDAKALSAKIAHELRTPLSVLK
STLQLALARNDSVDSMKRSLKESLRELDNLIQTSNDLLLISNIEKGIVNRFKPFDLSQTVLDVIENQMVLNPDKQFHINV
PPAVTFNGVETLLARAVANLIENAVKYSREGTIEIKLKCDDKSIIIEIINPGEEIPPQELERIFENFYRRKNVDKIEGYG
LGLSVARAVAKLHGGDVIYNYKNGLNCFAIYLPRIS
>Mature_435_residues
TLKAKISLLYLIAYGSSLLFLAAFLYAIVYDLKYREVDNRLLAFYGNIVRAYTIGNAPRTGLLNLPGSEDLGFEIYKNDR
LIASFRIKGGLFKNVEAPGTGFGNYGNYRYYISEESVNGAQYKFVVAHNLAPIRNFLKNLLIALIAGSLFVVILITLIGI
FITRKLLNPIGEIGKQLEEISHTEIDGRRVNVKITGSEIARLQSEVNKSLKRLELLIKDAKALSAKIAHELRTPLSVLKS
TLQLALARNDSVDSMKRSLKESLRELDNLIQTSNDLLLISNIEKGIVNRFKPFDLSQTVLDVIENQMVLNPDKQFHINVP
PAVTFNGVETLLARAVANLIENAVKYSREGTIEIKLKCDDKSIIIEIINPGEEIPPQELERIFENFYRRKNVDKIEGYGL
GLSVARAVAKLHGGDVIYNYKNGLNCFAIYLPRIS

Specific function: Probable member of a two-component regulatory system yedW/yedV. May activate yedW by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788279, Length=371, Percent_Identity=27.2237196765499, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786783, Length=348, Percent_Identity=27.0114942528736, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=31.6742081447964, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790551, Length=293, Percent_Identity=27.9863481228669, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789403, Length=336, Percent_Identity=26.4880952380952, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790346, Length=218, Percent_Identity=31.1926605504587, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87081816, Length=253, Percent_Identity=26.4822134387352, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=296, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=27.0833333333333, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788393, Length=268, Percent_Identity=26.1194029850746, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787894, Length=308, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=224, Percent_Identity=26.3392857142857, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786600, Length=203, Percent_Identity=28.0788177339901, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790861, Length=200, Percent_Identity=25.5, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787374, Length=286, Percent_Identity=23.7762237762238, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=257, Percent_Identity=26.0700389105058, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR006290
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48866; Mature: 48734

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKAKISLLYLIAYGSSLLFLAAFLYAIVYDLKYREVDNRLLAFYGNIVRAYTIGNAPR
CCEEHHHHHEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
TGLLNLPGSEDLGFEIYKNDRLIASFRIKGGLFKNVEAPGTGFGNYGNYRYYISEESVNG
CCEEECCCCCCCCEEEEECCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
AQYKFVVAHNLAPIRNFLKNLLIALIAGSLFVVILITLIGIFITRKLLNPIGEIGKQLEE
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISHTEIDGRRVNVKITGSEIARLQSEVNKSLKRLELLIKDAKALSAKIAHELRTPLSVLK
HHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STLQLALARNDSVDSMKRSLKESLRELDNLIQTSNDLLLISNIEKGIVNRFKPFDLSQTV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCHHHHH
LDVIENQMVLNPDKQFHINVPPAVTFNGVETLLARAVANLIENAVKYSREGTIEIKLKCD
HHHHHCCEEECCCCEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
DKSIIIEIINPGEEIPPQELERIFENFYRRKNVDKIEGYGLGLSVARAVAKLHGGDVIYN
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEE
YKNGLNCFAIYLPRIS
CCCCCEEEEEEECCCC
>Mature Secondary Structure 
TLKAKISLLYLIAYGSSLLFLAAFLYAIVYDLKYREVDNRLLAFYGNIVRAYTIGNAPR
CEEHHHHHEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
TGLLNLPGSEDLGFEIYKNDRLIASFRIKGGLFKNVEAPGTGFGNYGNYRYYISEESVNG
CCEEECCCCCCCCEEEEECCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
AQYKFVVAHNLAPIRNFLKNLLIALIAGSLFVVILITLIGIFITRKLLNPIGEIGKQLEE
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISHTEIDGRRVNVKITGSEIARLQSEVNKSLKRLELLIKDAKALSAKIAHELRTPLSVLK
HHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STLQLALARNDSVDSMKRSLKESLRELDNLIQTSNDLLLISNIEKGIVNRFKPFDLSQTV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCHHHHH
LDVIENQMVLNPDKQFHINVPPAVTFNGVETLLARAVANLIENAVKYSREGTIEIKLKCD
HHHHHCCEEECCCCEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
DKSIIIEIINPGEEIPPQELERIFENFYRRKNVDKIEGYGLGLSVARAVAKLHGGDVIYN
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEE
YKNGLNCFAIYLPRIS
CCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]