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The map label for this gene is mraY

Identifier: 239617756

GI number: 239617756

Start: 1468076

End: 1469011

Strand: Reverse

Name: mraY

Synonym: Kole_1381

Alternate gene names: 239617756

Gene position: 1469011-1468076 (Counterclockwise)

Preceding gene: 239617757

Following gene: 239617755

Centisome position: 63.81

GC content: 42.2

Gene sequence:

>936_bases
GTGGAGAATAACGTAATTGTTTTTTTTCTTTCCTTTTTAAGTAGTGTCGTATTTATTGAGGGATTCAAACGTTTCCAGAA
AAAACTTCGAATCGGACAATACATTCGCGAAGAAGGCCCCGATCTTCATAACTACAAAACCGGAACCCCTACAGCAGCGG
GTCTCGTTTTCATCCCGATTTTCATTGCGGTACTTCTGAATTTCAACAGAGGCCCGGAAAGTTTTCTTATCGCATTCTCT
GCTCTTTCCTATGGGTTAATCGGAGCCATCGATGACTTCATGAAAATAAAGCGAAAAAACGCCTCGGGGATAACAGCCGT
TCAAAAATTGTTCATGCAATTTACGGCAGCTTTCATTATCGTTTATTTCATTCAGCAAATAAACCCCCATACGTATCTGA
TCGTTCCTTTCAGCGGTTATAAACTGGATTTGGGATGGTTCTATTATCTCCTTTCATCAGTGGTTATCGTTGGGGTCAGC
AACGCTGTGAATCTTACAGACGGTGTTGACGGCCTTGCGGGATTCGTTTTTATCGGTTCAATTGTACCTTTGCTCATTGT
AGGATACCAATCCGTTGTATATCTTTCCCTGATTGGCCTGCTGATGGGATTTTTATGGCATAACTGGCATCCAGCAAGTA
TCTTCATGGGGGATGCCGGTTCACTGGCACTCGGAGGGATTCTTGCAACCTCTTTCGCTCTGAACGGTCTGGAGCTTTTC
TTGATATTCTTTGGTTTTATCTTTCTACTGGAGACCCTGAGTGTTATTATACAGGTTACCTCATTCAAGTTCAGGGGAAA
ACGGGTTTTCAGGATGTCCCCTATTCATCATCATTTCGAACTTCTTGGCTGGAAAGAAGAAAAAATTGCGTTCCGTTTCT
CAACACTCGCTTTATTAGTTTCTTTACTCGGAATAATCGGCTGGAGGGAATTATAA

Upstream 100 bases:

>100_bases
CTGAAAAAAAACTGCCGCTATGGCGATCTGGTTTATTTCAAAGCATCAAGAGGTGTTGCACTCGAAGAAGCTATCCTGAG
TTTTCGTAGGAGGTTGCAGA

Downstream 100 bases:

>100_bases
TGTACTCCGGAAAAGCAGGGATAATCGGCCTTGGCGAGTCGAATTATCGACTTGTGGAGTATCTTCTACAAAATTCACAC
TCAGAAATCTTTGTTTCAGA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MENNVIVFFLSFLSSVVFIEGFKRFQKKLRIGQYIREEGPDLHNYKTGTPTAAGLVFIPIFIAVLLNFNRGPESFLIAFS
ALSYGLIGAIDDFMKIKRKNASGITAVQKLFMQFTAAFIIVYFIQQINPHTYLIVPFSGYKLDLGWFYYLLSSVVIVGVS
NAVNLTDGVDGLAGFVFIGSIVPLLIVGYQSVVYLSLIGLLMGFLWHNWHPASIFMGDAGSLALGGILATSFALNGLELF
LIFFGFIFLLETLSVIIQVTSFKFRGKRVFRMSPIHHHFELLGWKEEKIAFRFSTLALLVSLLGIIGWREL

Sequences:

>Translated_311_residues
MENNVIVFFLSFLSSVVFIEGFKRFQKKLRIGQYIREEGPDLHNYKTGTPTAAGLVFIPIFIAVLLNFNRGPESFLIAFS
ALSYGLIGAIDDFMKIKRKNASGITAVQKLFMQFTAAFIIVYFIQQINPHTYLIVPFSGYKLDLGWFYYLLSSVVIVGVS
NAVNLTDGVDGLAGFVFIGSIVPLLIVGYQSVVYLSLIGLLMGFLWHNWHPASIFMGDAGSLALGGILATSFALNGLELF
LIFFGFIFLLETLSVIIQVTSFKFRGKRVFRMSPIHHHFELLGWKEEKIAFRFSTLALLVSLLGIIGWREL
>Mature_311_residues
MENNVIVFFLSFLSSVVFIEGFKRFQKKLRIGQYIREEGPDLHNYKTGTPTAAGLVFIPIFIAVLLNFNRGPESFLIAFS
ALSYGLIGAIDDFMKIKRKNASGITAVQKLFMQFTAAFIIVYFIQQINPHTYLIVPFSGYKLDLGWFYYLLSSVVIVGVS
NAVNLTDGVDGLAGFVFIGSIVPLLIVGYQSVVYLSLIGLLMGFLWHNWHPASIFMGDAGSLALGGILATSFALNGLELF
LIFFGFIFLLETLSVIIQVTSFKFRGKRVFRMSPIHHHFELLGWKEEKIAFRFSTLALLVSLLGIIGWREL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=306, Percent_Identity=41.1764705882353, Blast_Score=201, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_KOSOT (C5CDR2)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941078.1
- GeneID:   7968693
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_1381
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 34840; Mature: 34840

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x282c3814)-; HASH(0x26f61b1c)-; HASH(0x26f1394c)-; HASH(0x26f61834)-; HASH(0x29d8cd20)-; HASH(0x2939eaf4)-; HASH(0x29d9704c)-; HASH(0x29d8cb1c)-; HASH(0x292ce11c)-; HASH(0x29d8cabc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNVIVFFLSFLSSVVFIEGFKRFQKKLRIGQYIREEGPDLHNYKTGTPTAAGLVFIPI
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
FIAVLLNFNRGPESFLIAFSALSYGLIGAIDDFMKIKRKNASGITAVQKLFMQFTAAFII
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VYFIQQINPHTYLIVPFSGYKLDLGWFYYLLSSVVIVGVSNAVNLTDGVDGLAGFVFIGS
HHHHHHCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
IVPLLIVGYQSVVYLSLIGLLMGFLWHNWHPASIFMGDAGSLALGGILATSFALNGLELF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
LIFFGFIFLLETLSVIIQVTSFKFRGKRVFRMSPIHHHFELLGWKEEKIAFRFSTLALLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHH
SLLGIIGWREL
HHHHHHCCCCH
>Mature Secondary Structure
MENNVIVFFLSFLSSVVFIEGFKRFQKKLRIGQYIREEGPDLHNYKTGTPTAAGLVFIPI
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
FIAVLLNFNRGPESFLIAFSALSYGLIGAIDDFMKIKRKNASGITAVQKLFMQFTAAFII
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VYFIQQINPHTYLIVPFSGYKLDLGWFYYLLSSVVIVGVSNAVNLTDGVDGLAGFVFIGS
HHHHHHCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
IVPLLIVGYQSVVYLSLIGLLMGFLWHNWHPASIFMGDAGSLALGGILATSFALNGLELF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
LIFFGFIFLLETLSVIIQVTSFKFRGKRVFRMSPIHHHFELLGWKEEKIAFRFSTLALLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHH
SLLGIIGWREL
HHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA