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The map label for this gene is arsB [C]

Identifier: 239617635

GI number: 239617635

Start: 1332918

End: 1334198

Strand: Direct

Name: arsB [C]

Synonym: Kole_1256

Alternate gene names: 239617635

Gene position: 1332918-1334198 (Clockwise)

Preceding gene: 239617634

Following gene: 239617638

Centisome position: 57.9

GC content: 37.39

Gene sequence:

>1281_bases
ATGGATATAAATGTGTTGATAACTTTAGTGATTGTGGTTATTGTGTATGGATTCATCATTTTTGGTAAAAAGAACAAAGC
TGTTGTCGTCTTTGGGCTATCACTGGTTATTGCGGCATTAAAACTAGTAGAAGGGCTTGATCCTGAAAACATCAGCAAGG
TGGTTGATCTAGACACCCTGGGCCTTTTGCTAGGTATGATGATAATTGTTGCCTTTTTAAATACTTCAGGTTTTTTCGAA
TATTTCTCGATAAAGGTGATAAAGTTTGGCGGAGAGCGTTTTTATTTCACATTGACCCTTTTGATGATCGTTGTGGCATT
AACTTCGGCCTTTCTTGATAACGTGGTTACTATAATCGTCATGGCTCCAATGATGTTTTTGATAGCGGATATGCTTGGGA
TGGATCCAGTACCTTTAATAGTGTTGACATTGGTGATCGATAATATTGGGGGTGGGGCCACCTTGATAGGTAGTCCATTT
AATTTAGTCCTTGGCTCAATAAGCGGTTTTTCCTTCAACGATTTCATCATAAAACTTGGTCCAGCTTCTATATTTGCTTT
TATAGCAGTGATGCTTTATTTCAAAAGATTCATTAAAGTGGACGAGTCTGTTGTGAGTAAAATTAGAAGGCTTAGTGAAA
TGGATGAAGGAAGAGCAATAAATGACAAAAAAATGATGAAAATGTCTCTTGCGGTATTTCTTACGGTAATTGTTCTTTTT
GTTATTCATAATCTGATTGATGTTGACCTTTCCTATATCGCGCTTTTGGGTGGTGTTTTCCTTCTTGTGGTAAACAAAAA
AGATTTTGAATATGTCGCTGCCAAGATAGACTGGGATATGCTATTTTTCTTTGCGGGCTTGTATATCACCTCTTATGCTC
TTGAGTCAGTAGGAATTACGAGTCTGATTGCTGAAGGATTGAAATCAGTGATGAATAACCAGCTAATGATATTGCTAACG
CCCTTCATACTAGCCGCGATTAGTGTTCCAATATTAAACAACGTTCCAGCTGCGCTCATATTTGGTCCCGTTCTCAAAAT
ATTGGTAGGAGCTGGTTTCCCAACAATAATTTGGTGGTCTTTTGCATTAAGTGGAAACTTAGCTACAAGCTTAACACCAT
TGGGAGCAGTACAAAATATAGTAGCTGTAACCTATTTAGAAAAAGAGATTGGACGTTCTTTCGGTTTTAGAGAATATTTA
CGTTGGATGATAGCCCCTGTGGCTATAAGTCTTGTAATTGGGTTGATATACATATTTGGGCTCTTCATAGTATCTAAGTA
A

Upstream 100 bases:

>100_bases
CTTTCAAATTTCATATTCTTCAGTTCTATTTGATAGAATGGATAATTGTTAGAAGTTATCTGATTTTGATATATTACCAA
GATAAGGAGATAGAAGCGAC

Downstream 100 bases:

>100_bases
AAAATCTTGTAGAATCTCATCTTTTAAGCTTGACTATCATCCTGAACTTGATTCAGGATCTATCATTCTTGATCTCTCGG
ATCTCGCCTTCTCGGTTCTC

Product: Citrate transporter

Products: ADP; phosphate; arsenite [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MDINVLITLVIVVIVYGFIIFGKKNKAVVVFGLSLVIAALKLVEGLDPENISKVVDLDTLGLLLGMMIIVAFLNTSGFFE
YFSIKVIKFGGERFYFTLTLLMIVVALTSAFLDNVVTIIVMAPMMFLIADMLGMDPVPLIVLTLVIDNIGGGATLIGSPF
NLVLGSISGFSFNDFIIKLGPASIFAFIAVMLYFKRFIKVDESVVSKIRRLSEMDEGRAINDKKMMKMSLAVFLTVIVLF
VIHNLIDVDLSYIALLGGVFLLVVNKKDFEYVAAKIDWDMLFFFAGLYITSYALESVGITSLIAEGLKSVMNNQLMILLT
PFILAAISVPILNNVPAALIFGPVLKILVGAGFPTIIWWSFALSGNLATSLTPLGAVQNIVAVTYLEKEIGRSFGFREYL
RWMIAPVAISLVIGLIYIFGLFIVSK

Sequences:

>Translated_426_residues
MDINVLITLVIVVIVYGFIIFGKKNKAVVVFGLSLVIAALKLVEGLDPENISKVVDLDTLGLLLGMMIIVAFLNTSGFFE
YFSIKVIKFGGERFYFTLTLLMIVVALTSAFLDNVVTIIVMAPMMFLIADMLGMDPVPLIVLTLVIDNIGGGATLIGSPF
NLVLGSISGFSFNDFIIKLGPASIFAFIAVMLYFKRFIKVDESVVSKIRRLSEMDEGRAINDKKMMKMSLAVFLTVIVLF
VIHNLIDVDLSYIALLGGVFLLVVNKKDFEYVAAKIDWDMLFFFAGLYITSYALESVGITSLIAEGLKSVMNNQLMILLT
PFILAAISVPILNNVPAALIFGPVLKILVGAGFPTIIWWSFALSGNLATSLTPLGAVQNIVAVTYLEKEIGRSFGFREYL
RWMIAPVAISLVIGLIYIFGLFIVSK
>Mature_426_residues
MDINVLITLVIVVIVYGFIIFGKKNKAVVVFGLSLVIAALKLVEGLDPENISKVVDLDTLGLLLGMMIIVAFLNTSGFFE
YFSIKVIKFGGERFYFTLTLLMIVVALTSAFLDNVVTIIVMAPMMFLIADMLGMDPVPLIVLTLVIDNIGGGATLIGSPF
NLVLGSISGFSFNDFIIKLGPASIFAFIAVMLYFKRFIKVDESVVSKIRRLSEMDEGRAINDKKMMKMSLAVFLTVIVLF
VIHNLIDVDLSYIALLGGVFLLVVNKKDFEYVAAKIDWDMLFFFAGLYITSYALESVGITSLIAEGLKSVMNNQLMILLT
PFILAAISVPILNNVPAALIFGPVLKILVGAGFPTIIWWSFALSGNLATSLTPLGAVQNIVAVTYLEKEIGRSFGFREYL
RWMIAPVAISLVIGLIYIFGLFIVSK

Specific function: Involved In Arsenical Resistance. Thought To Form The Channel Of An Arsenite Pump (By Similarity). [C]

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=509, Percent_Identity=25.147347740668, Blast_Score=135, Evalue=5e-32,
Organism=Escherichia coli, GI87082277, Length=378, Percent_Identity=23.5449735449735, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28574683, Length=430, Percent_Identity=24.4186046511628, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28574681, Length=430, Percent_Identity=24.4186046511628, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28574685, Length=430, Percent_Identity=24.4186046511628, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28574678, Length=430, Percent_Identity=24.4186046511628, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI19920704, Length=430, Percent_Identity=24.4186046511628, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24581759, Length=430, Percent_Identity=24.4186046511628, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI221472711, Length=437, Percent_Identity=23.1121281464531, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24581764, Length=437, Percent_Identity=23.1121281464531, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24656008, Length=362, Percent_Identity=20.9944751381215, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550608, Length=227, Percent_Identity=28.1938325991189, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 46687; Mature: 46687

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINVLITLVIVVIVYGFIIFGKKNKAVVVFGLSLVIAALKLVEGLDPENISKVVDLDTL
CCHHHHHHHHHHHHHHHHHEECCCCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GLLLGMMIIVAFLNTSGFFEYFSIKVIKFGGERFYFTLTLLMIVVALTSAFLDNVVTIIV
HHHHHHHHHHHHHCCCCCHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAPMMFLIADMLGMDPVPLIVLTLVIDNIGGGATLIGSPFNLVLGSISGFSFNDFIIKLG
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCCCCCCCCCEEEEC
PASIFAFIAVMLYFKRFIKVDESVVSKIRRLSEMDEGRAINDKKMMKMSLAVFLTVIVLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VIHNLIDVDLSYIALLGGVFLLVVNKKDFEYVAAKIDWDMLFFFAGLYITSYALESVGIT
HHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHH
SLIAEGLKSVMNNQLMILLTPFILAAISVPILNNVPAALIFGPVLKILVGAGFPTIIWWS
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHH
FALSGNLATSLTPLGAVQNIVAVTYLEKEIGRSFGFREYLRWMIAPVAISLVIGLIYIFG
HHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LFIVSK
HHHHCC
>Mature Secondary Structure
MDINVLITLVIVVIVYGFIIFGKKNKAVVVFGLSLVIAALKLVEGLDPENISKVVDLDTL
CCHHHHHHHHHHHHHHHHHEECCCCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GLLLGMMIIVAFLNTSGFFEYFSIKVIKFGGERFYFTLTLLMIVVALTSAFLDNVVTIIV
HHHHHHHHHHHHHCCCCCHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAPMMFLIADMLGMDPVPLIVLTLVIDNIGGGATLIGSPFNLVLGSISGFSFNDFIIKLG
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCCCCCCCCCEEEEC
PASIFAFIAVMLYFKRFIKVDESVVSKIRRLSEMDEGRAINDKKMMKMSLAVFLTVIVLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VIHNLIDVDLSYIALLGGVFLLVVNKKDFEYVAAKIDWDMLFFFAGLYITSYALESVGIT
HHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHH
SLIAEGLKSVMNNQLMILLTPFILAAISVPILNNVPAALIFGPVLKILVGAGFPTIIWWS
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHH
FALSGNLATSLTPLGAVQNIVAVTYLEKEIGRSFGFREYLRWMIAPVAISLVIGLIYIFG
HHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LFIVSK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arsenite [Cytoplasm]; H2O [C]

Specific reaction: ATP + arsenite [Cytoplasm] + H2O = ADP + phosphate + arsenite [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]