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The map label for this gene is udp [H]

Identifier: 239617634

GI number: 239617634

Start: 1331617

End: 1332378

Strand: Direct

Name: udp [H]

Synonym: Kole_1255

Alternate gene names: 239617634

Gene position: 1331617-1332378 (Clockwise)

Preceding gene: 239617633

Following gene: 239617635

Centisome position: 57.84

GC content: 38.19

Gene sequence:

>762_bases
ATGGAAGATCCAAGATACCACATAAGAATAGACGATCCAGAAAAAGTAGGAAAATACGTTTTATTACCAGGGGATAGGGG
AAGAGTAAAAAGAATTGCAAAGTATTTGGAAAATGCAGAGGTCGTTGGAGACAACAGAGAATATTTTACAATGACAGGCT
ATTTGAACGGAGAAAAGGTATCTGTAATGTCCACGGGAATGGGAGCACCGTGTATGTCAATAGGTGTAGAAGAGCTAAAA
ACTTTGGGTGTTCATACATACATCCGGATAGGGACAACAGGAGCTATGCAACCAAATCTGAAACTCGGTGATTCAATAGT
TCCAACAGCCGCAATTAGAGGCGACGGAACTATGGATTATTATTTACCAAAATCATTCCCTGCGGTTGGACATTTTGATG
TAATTTCAGCTCTGAAAGAGGCTGCTGGAATAATCGGCAATCCGCATCATTTAGGCGTTGTACTTTCCACCGATTCATAC
TATGGAAGATTCTTCAATTCCAAAAAAGCTGCTGAAGAAGTGGATTTATTCGTAAGAGCACATACATTAGCGGTTGAAAT
GGAAGTGTCTGCTTTATATATTTTAGGAAATGTACATAACTTAAGAACCGGTGCAATCTTAACCGTAAGAGAAGAATTGG
GTGAAGATGGGGCTTATGTAAAGCAAGCAGGAGAAGAATATGAAAAAGGATTGGAAAAATCCATACAAATAGCAATAAAA
GCAATTGAATTGTTGATAGAAAAAGATAAAGGTAATGCGTAA

Upstream 100 bases:

>100_bases
TGATAGAGAGAAGTTCATTGAAATACTTTTTGATAATTTAAAGAAATACAATTAATTTAATTCTAAATTCTATTCTAAAA
GAAAGGAGAGAGGTGAAACC

Downstream 100 bases:

>100_bases
TGTGATGTGCGTATAAGGTCGATAGATTTTTCCCCTGAAAGGCCGTAGAAAAAGGGGACAGTCCCATTGTGGACTGTCCC
CTTTTTTCACTTGTGAACTT

Product: purine or other phosphorylase family 1

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MEDPRYHIRIDDPEKVGKYVLLPGDRGRVKRIAKYLENAEVVGDNREYFTMTGYLNGEKVSVMSTGMGAPCMSIGVEELK
TLGVHTYIRIGTTGAMQPNLKLGDSIVPTAAIRGDGTMDYYLPKSFPAVGHFDVISALKEAAGIIGNPHHLGVVLSTDSY
YGRFFNSKKAAEEVDLFVRAHTLAVEMEVSALYILGNVHNLRTGAILTVREELGEDGAYVKQAGEEYEKGLEKSIQIAIK
AIELLIEKDKGNA

Sequences:

>Translated_253_residues
MEDPRYHIRIDDPEKVGKYVLLPGDRGRVKRIAKYLENAEVVGDNREYFTMTGYLNGEKVSVMSTGMGAPCMSIGVEELK
TLGVHTYIRIGTTGAMQPNLKLGDSIVPTAAIRGDGTMDYYLPKSFPAVGHFDVISALKEAAGIIGNPHHLGVVLSTDSY
YGRFFNSKKAAEEVDLFVRAHTLAVEMEVSALYILGNVHNLRTGAILTVREELGEDGAYVKQAGEEYEKGLEKSIQIAIK
AIELLIEKDKGNA
>Mature_253_residues
MEDPRYHIRIDDPEKVGKYVLLPGDRGRVKRIAKYLENAEVVGDNREYFTMTGYLNGEKVSVMSTGMGAPCMSIGVEELK
TLGVHTYIRIGTTGAMQPNLKLGDSIVPTAAIRGDGTMDYYLPKSFPAVGHFDVISALKEAAGIIGNPHHLGVVLSTDSY
YGRFFNSKKAAEEVDLFVRAHTLAVEMEVSALYILGNVHNLRTGAILTVREELGEDGAYVKQAGEEYEKGLEKSIQIAIK
AIELLIEKDKGNA

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=196, Percent_Identity=38.265306122449, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790844, Length=229, Percent_Identity=30.5676855895196, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 27724; Mature: 27724

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDPRYHIRIDDPEKVGKYVLLPGDRGRVKRIAKYLENAEVVGDNREYFTMTGYLNGEKV
CCCCEEEEEECCHHHHCCEEEECCCCHHHHHHHHHHCCCEEECCCCEEEEEEEEECCCEE
SVMSTGMGAPCMSIGVEELKTLGVHTYIRIGTTGAMQPNLKLGDSIVPTAAIRGDGTMDY
EEEECCCCCCHHHHCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCEEE
YLPKSFPAVGHFDVISALKEAAGIIGNPHHLGVVLSTDSYYGRFFNSKKAAEEVDLFVRA
ECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHCCHHHHHHHHHHEEE
HTLAVEMEVSALYILGNVHNLRTGAILTVREELGEDGAYVKQAGEEYEKGLEKSIQIAIK
EEEEEEEEEEEEEEEECCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AIELLIEKDKGNA
HHHHHHCCCCCCC
>Mature Secondary Structure
MEDPRYHIRIDDPEKVGKYVLLPGDRGRVKRIAKYLENAEVVGDNREYFTMTGYLNGEKV
CCCCEEEEEECCHHHHCCEEEECCCCHHHHHHHHHHCCCEEECCCCEEEEEEEEECCCEE
SVMSTGMGAPCMSIGVEELKTLGVHTYIRIGTTGAMQPNLKLGDSIVPTAAIRGDGTMDY
EEEECCCCCCHHHHCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCEEE
YLPKSFPAVGHFDVISALKEAAGIIGNPHHLGVVLSTDSYYGRFFNSKKAAEEVDLFVRA
ECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHCCHHHHHHHHHHEEE
HTLAVEMEVSALYILGNVHNLRTGAILTVREELGEDGAYVKQAGEEYEKGLEKSIQIAIK
EEEEEEEEEEEEEEEECCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AIELLIEKDKGNA
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]