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The map label for this gene is ribE [H]

Identifier: 239617611

GI number: 239617611

Start: 1309761

End: 1310318

Strand: Direct

Name: ribE [H]

Synonym: Kole_1232

Alternate gene names: 239617611

Gene position: 1309761-1310318 (Clockwise)

Preceding gene: 239617610

Following gene: 239617612

Centisome position: 56.89

GC content: 44.09

Gene sequence:

>558_bases
ATGTTCACAGGTATAGTGGAATATGTTTCAAAAATGGAAATACGTGGAAACACGCTGGTTATCGAGAATCCGTTTGATGA
CGTGAAGATAGGGGACAGCATTTCGGTAAACGGTGTGTGCCTTACAGCAACGGCAGTTGGAAGGTACATAACCTTTACCT
GTGGGCTGGAAACACTCAAACGCACCAACCTTGGCATATGGAACGGAAGGGAAGCAAACATAGAGCGCGCGCTACCTGTT
AATGGAAGATTTGATGGCCATATAGTTACAGGGCATATCGACGGCACAATCAAGTTCTTAAAAAGTTTAAAAGAAAGGGA
AACAACATGGATGACCTTCTCCATGCCGAGGGAACGTTGGGGAATTGCCGAAAAAGGGTCGATCGCGATTAACGGCATTA
GCCTAACAATCGCAAAGATAGATCTCGATACATTTACCGTGCAAGTCATACCGCATACATTTGAAAACACAAACCTTAGA
ACGCTTCATCCAGGTGACATAGTGAATTACGAGATAGACGTTATCGCGCGCTACTTGAAAGGAATTTATAAGGGGTGA

Upstream 100 bases:

>100_bases
CCTTTGGAAATGGGCTTTCCCCATTTGATCGTAAATTTAAAGGATTCACGACGAAAAGAGTAGAGGTGTACCATCCAGAC
ATTTACTGGGAGTTGATACC

Downstream 100 bases:

>100_bases
GTATATGGAGATATCGAAAATTAGAAAGGCATTTTTGGACAGAAAACCAATTGTGCTCATAGATGATAAACGCGAGATGG
AGGCAGATCTCATCTTTCCA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MFTGIVEYVSKMEIRGNTLVIENPFDDVKIGDSISVNGVCLTATAVGRYITFTCGLETLKRTNLGIWNGREANIERALPV
NGRFDGHIVTGHIDGTIKFLKSLKERETTWMTFSMPRERWGIAEKGSIAINGISLTIAKIDLDTFTVQVIPHTFENTNLR
TLHPGDIVNYEIDVIARYLKGIYKG

Sequences:

>Translated_185_residues
MFTGIVEYVSKMEIRGNTLVIENPFDDVKIGDSISVNGVCLTATAVGRYITFTCGLETLKRTNLGIWNGREANIERALPV
NGRFDGHIVTGHIDGTIKFLKSLKERETTWMTFSMPRERWGIAEKGSIAINGISLTIAKIDLDTFTVQVIPHTFENTNLR
TLHPGDIVNYEIDVIARYLKGIYKG
>Mature_185_residues
MFTGIVEYVSKMEIRGNTLVIENPFDDVKIGDSISVNGVCLTATAVGRYITFTCGLETLKRTNLGIWNGREANIERALPV
NGRFDGHIVTGHIDGTIKFLKSLKERETTWMTFSMPRERWGIAEKGSIAINGISLTIAKIDLDTFTVQVIPHTFENTNLR
TLHPGDIVNYEIDVIARYLKGIYKG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=185, Percent_Identity=36.7567567567568, Blast_Score=89, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319733, Length=210, Percent_Identity=33.8095238095238, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 20679; Mature: 20679

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVEYVSKMEIRGNTLVIENPFDDVKIGDSISVNGVCLTATAVGRYITFTCGLETLK
CCCHHHHHHHHEEECCCEEEEECCCCCCCCCCCEEECCEEEEEECCCCEEEEEECHHHHH
RTNLGIWNGREANIERALPVNGRFDGHIVTGHIDGTIKFLKSLKERETTWMTFSMPRERW
HCCCCEECCCCCCCEEECCCCCCCCCEEEEEEECHHHHHHHHHHHCCCEEEEEECCHHHC
GIAEKGSIAINGISLTIAKIDLDTFTVQVIPHTFENTNLRTLHPGDIVNYEIDVIARYLK
CCCCCCCEEEEEEEEEEEEEECCEEEEEEEEEECCCCCEEEECCCCEEEEEHHHHHHHHH
GIYKG
HHHCC
>Mature Secondary Structure
MFTGIVEYVSKMEIRGNTLVIENPFDDVKIGDSISVNGVCLTATAVGRYITFTCGLETLK
CCCHHHHHHHHEEECCCEEEEECCCCCCCCCCCEEECCEEEEEECCCCEEEEEECHHHHH
RTNLGIWNGREANIERALPVNGRFDGHIVTGHIDGTIKFLKSLKERETTWMTFSMPRERW
HCCCCEECCCCCCCEEECCCCCCCCCEEEEEEECHHHHHHHHHHHCCCEEEEEECCHHHC
GIAEKGSIAINGISLTIAKIDLDTFTVQVIPHTFENTNLRTLHPGDIVNYEIDVIARYLK
CCCCCCCEEEEEEEEEEEEEECCEEEEEEEEEECCCCCEEEECCCCEEEEEHHHHHHHHH
GIYKG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]