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The map label for this gene is ribD [H]

Identifier: 239617610

GI number: 239617610

Start: 1308739

End: 1309776

Strand: Direct

Name: ribD [H]

Synonym: Kole_1231

Alternate gene names: 239617610

Gene position: 1308739-1309776 (Clockwise)

Preceding gene: 239617603

Following gene: 239617611

Centisome position: 56.85

GC content: 42.1

Gene sequence:

>1038_bases
ATGGATGAAAAATTTATGGAGCTTGCTATCGAGGAGGCAAGAAAAGGGGAAGGGCTGGTAAATCCCAACCCGCTTGTAGG
GGCTGTAATCGTCAAAAATGGAAAAATTTTGTCCACTGGTTACCATGAATACTTTGGTGGAAGGCACGCGGAAATTGTAG
CCATTGAGAACGCGAAAAAAATGGGGTATGACATCAAGGGAGCTGAGATATATGTAACGCTCGAACCCTGTGTCCATTAT
GGAAAAACGCCGCCTTGTACTGACAGGATTATAAGAGAAGGGTTCTCAGCTGTGTACATTGGAACCCTGGACCCAAATCC
CATGGTCCACGGAAAAGGCGAGGAAAAACTAAAAAACGCCGGAATATGCGTAAAGCACGGAATTTTAGAGGTCAAGGCAA
AGGAATTGATCGAGGTTTTCGCAAAGTATATGAAAACAAAAATGCCTTTCGTTGCGTTGAAACTCGCTATGAGCTTAGAT
GGGTTCATTACAAGCATGCGTGGAAAACGCGAAAGGATTACATCAGATCGGGCAAGAGAAAAGGTTCATAGATTAAGAAA
CTACTACTCAGCAATAATGATTGGTTCAAAAACCGCCATTTCTGACGACCCTCTTTTGACCTGCCGATATTCATTTTGCA
AAAGAAATCCAATTCGTATCATCCTGGATAGATCCGGGAAAACTGCGAAAGTGAATCTAAAACTCTTTGCCCAAGAAGGA
AGGACGATAATCTTCACATCTTCGAATGAGCGTTGGCCTGAAAATGTTGAAGTTATCCGAAAAGATGATTTATCTCCAGA
ACCAATATTAAAAGCACTTGGAAAAATGGGGATAGATTCCGTTCTCGTTGAAGGAGGCGCAAATGTTGCATCCCAGTTTA
TCAACTATGCCGATAAAATTCACCTCTTCTATGCTCCAATAGCCTTTGGAAATGGGCTTTCCCCATTTGATCGTAAATTT
AAAGGATTCACGACGAAAAGAGTAGAGGTGTACCATCCAGACATTTACTGGGAGTTGATACCATGTTCACAGGTATAG

Upstream 100 bases:

>100_bases
AGGAGAATTGATAGTAGATAAAAAGCAATGTATATGTTGCGATATTGAATCTTAAAAGTCCCCGGAGTTTTCCGGGGACT
TTTTTCTTGGAGGAATGGAT

Downstream 100 bases:

>100_bases
TGGAATATGTTTCAAAAATGGAAATACGTGGAAACACGCTGGTTATCGAGAATCCGTTTGATGACGTGAAGATAGGGGAC
AGCATTTCGGTAAACGGTGT

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MDEKFMELAIEEARKGEGLVNPNPLVGAVIVKNGKILSTGYHEYFGGRHAEIVAIENAKKMGYDIKGAEIYVTLEPCVHY
GKTPPCTDRIIREGFSAVYIGTLDPNPMVHGKGEEKLKNAGICVKHGILEVKAKELIEVFAKYMKTKMPFVALKLAMSLD
GFITSMRGKRERITSDRAREKVHRLRNYYSAIMIGSKTAISDDPLLTCRYSFCKRNPIRIILDRSGKTAKVNLKLFAQEG
RTIIFTSSNERWPENVEVIRKDDLSPEPILKALGKMGIDSVLVEGGANVASQFINYADKIHLFYAPIAFGNGLSPFDRKF
KGFTTKRVEVYHPDIYWELIPCSQV

Sequences:

>Translated_345_residues
MDEKFMELAIEEARKGEGLVNPNPLVGAVIVKNGKILSTGYHEYFGGRHAEIVAIENAKKMGYDIKGAEIYVTLEPCVHY
GKTPPCTDRIIREGFSAVYIGTLDPNPMVHGKGEEKLKNAGICVKHGILEVKAKELIEVFAKYMKTKMPFVALKLAMSLD
GFITSMRGKRERITSDRAREKVHRLRNYYSAIMIGSKTAISDDPLLTCRYSFCKRNPIRIILDRSGKTAKVNLKLFAQEG
RTIIFTSSNERWPENVEVIRKDDLSPEPILKALGKMGIDSVLVEGGANVASQFINYADKIHLFYAPIAFGNGLSPFDRKF
KGFTTKRVEVYHPDIYWELIPCSQV
>Mature_345_residues
MDEKFMELAIEEARKGEGLVNPNPLVGAVIVKNGKILSTGYHEYFGGRHAEIVAIENAKKMGYDIKGAEIYVTLEPCVHY
GKTPPCTDRIIREGFSAVYIGTLDPNPMVHGKGEEKLKNAGICVKHGILEVKAKELIEVFAKYMKTKMPFVALKLAMSLD
GFITSMRGKRERITSDRAREKVHRLRNYYSAIMIGSKTAISDDPLLTCRYSFCKRNPIRIILDRSGKTAKVNLKLFAQEG
RTIIFTSSNERWPENVEVIRKDDLSPEPILKALGKMGIDSVLVEGGANVASQFINYADKIHLFYAPIAFGNGLSPFDRKF
KGFTTKRVEVYHPDIYWELIPCSQV

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=331, Percent_Identity=38.0664652567976, Blast_Score=215, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 38770; Mature: 38770

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEKFMELAIEEARKGEGLVNPNPLVGAVIVKNGKILSTGYHEYFGGRHAEIVAIENAKK
CCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEECCCHHHHCCCCEEEEEEECHHH
MGYDIKGAEIYVTLEPCVHYGKTPPCTDRIIREGFSAVYIGTLDPNPMVHGKGEEKLKNA
CCCEECCCEEEEEEEHHHCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHC
GICVKHGILEVKAKELIEVFAKYMKTKMPFVALKLAMSLDGFITSMRGKRERITSDRARE
CEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KVHRLRNYYSAIMIGSKTAISDDPLLTCRYSFCKRNPIRIILDRSGKTAKVNLKLFAQEG
HHHHHHHHHHHEEECCCCCCCCCCEEEEEHHHHCCCCEEEEEECCCCEEEEEEEEEECCC
RTIIFTSSNERWPENVEVIRKDDLSPEPILKALGKMGIDSVLVEGGANVASQFINYADKI
CEEEEECCCCCCCCCHHHEECCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHEE
HLFYAPIAFGNGLSPFDRKFKGFTTKRVEVYHPDIYWELIPCSQV
EEEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCEEEEEECCCCC
>Mature Secondary Structure
MDEKFMELAIEEARKGEGLVNPNPLVGAVIVKNGKILSTGYHEYFGGRHAEIVAIENAKK
CCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEEECCCHHHHCCCCEEEEEEECHHH
MGYDIKGAEIYVTLEPCVHYGKTPPCTDRIIREGFSAVYIGTLDPNPMVHGKGEEKLKNA
CCCEECCCEEEEEEEHHHCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHC
GICVKHGILEVKAKELIEVFAKYMKTKMPFVALKLAMSLDGFITSMRGKRERITSDRARE
CEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KVHRLRNYYSAIMIGSKTAISDDPLLTCRYSFCKRNPIRIILDRSGKTAKVNLKLFAQEG
HHHHHHHHHHHEEECCCCCCCCCCEEEEEHHHHCCCCEEEEEECCCCEEEEEEEEEECCC
RTIIFTSSNERWPENVEVIRKDDLSPEPILKALGKMGIDSVLVEGGANVASQFINYADKI
CEEEEECCCCCCCCCHHHEECCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHEE
HLFYAPIAFGNGLSPFDRKFKGFTTKRVEVYHPDIYWELIPCSQV
EEEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]