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The map label for this gene is glmS [H]

Identifier: 239617567

GI number: 239617567

Start: 1257797

End: 1258717

Strand: Direct

Name: glmS [H]

Synonym: Kole_1185

Alternate gene names: 239617567

Gene position: 1257797-1258717 (Clockwise)

Preceding gene: 239617566

Following gene: 239617568

Centisome position: 54.64

GC content: 42.56

Gene sequence:

>921_bases
ATGGAAAACGTTACTTTGAGCGAAATAAAGAGAACTCCGGAGCTCTTGAAGCAGGTTGAATCTGTTCCTTTCAAACTTGA
AAAAGGAAAGCGTTATCTTTTTGTTGGTTGCGGCTCTTCATATAATCTCGGATACATAGCGGCGGAAATGCTTAACAAAA
ACGGTTATGAGGCAGATGTTGTGACCGGGGGAAAGATAGTTGCTTTAGGAGATTTTCCAGAAGCGGATGTTGCGTTTTTT
ATATCTCGTACAGGGGAGTCTACCGAGACAGTGCTTGCTGCAAAAGCGTTAAAAAAGAGGGGAATATACACGATCAGCAT
TGTTTGTGCGAAGGATGCGGAGCTTTCAAAGACCTGTGAGGAAAACATAGAGCTGCCCTTCGCAGACGAAGAAAGTGTCG
TCATGACAGGGTCATTTTCAACGATTCTTTACATGATTTTGCGCGGAATTAAGAGATACTCCATTGATGGGATAGAAGGG
TTCCTGGGAAAGTCCTTTGAATATGTTGATAGGTTGGAGCTGAAAAAATTCAGTCATTTTGTATTTTTGGGATTTGACGA
ACTTTATGGGCTCGCTAAAGAAAGCGCCCTTAAGGTTCAAGAGATGGCCCTTCAATGGGTGGAGTTCCACGAACCTTTGG
ATTACAGACACGGTCCAAAGGCCACGCTTACTGAAAAGACACTTGTTGTTATGTATTCTAAAGACACCGCGTACGAGGTC
GAACTTGCTAAAGAACTCAAGCAGATGGGAGCAGGCGTGGTTTATATTGGTAAAGAAGGTGATATAGAGATTCCATATCA
AGACGGGTTTGAAACGCCGGTAAGGATATTGCCAGTACAATATCTTGCGTATAAGAAAGCAGTTTCTCTTGGCTTGAATC
CGGACAAGCCAAAAAATCTTACAAAATCGGTGAAGTTGTAA

Upstream 100 bases:

>100_bases
CGGTTTTCCATAGAATGGAAGAAAAAGGTAGAAAATTTATAGAAAGAACAGCTGATTCGGTGGCAAAGTGGATATATTAA
AAAGATGGTTGGAGGTGCTT

Downstream 100 bases:

>100_bases
CAATAGTGCTTGGTTGTTAGTTGGCGGTTTATAGTTGACAGTAGTTAGTTGATAGTTGGTATTGAGACAAACGAGCTCCC
GGAATTAAGAACGGGAGCTT

Product: sugar isomerase (SIS)

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MENVTLSEIKRTPELLKQVESVPFKLEKGKRYLFVGCGSSYNLGYIAAEMLNKNGYEADVVTGGKIVALGDFPEADVAFF
ISRTGESTETVLAAKALKKRGIYTISIVCAKDAELSKTCEENIELPFADEESVVMTGSFSTILYMILRGIKRYSIDGIEG
FLGKSFEYVDRLELKKFSHFVFLGFDELYGLAKESALKVQEMALQWVEFHEPLDYRHGPKATLTEKTLVVMYSKDTAYEV
ELAKELKQMGAGVVYIGKEGDIEIPYQDGFETPVRILPVQYLAYKKAVSLGLNPDKPKNLTKSVKL

Sequences:

>Translated_306_residues
MENVTLSEIKRTPELLKQVESVPFKLEKGKRYLFVGCGSSYNLGYIAAEMLNKNGYEADVVTGGKIVALGDFPEADVAFF
ISRTGESTETVLAAKALKKRGIYTISIVCAKDAELSKTCEENIELPFADEESVVMTGSFSTILYMILRGIKRYSIDGIEG
FLGKSFEYVDRLELKKFSHFVFLGFDELYGLAKESALKVQEMALQWVEFHEPLDYRHGPKATLTEKTLVVMYSKDTAYEV
ELAKELKQMGAGVVYIGKEGDIEIPYQDGFETPVRILPVQYLAYKKAVSLGLNPDKPKNLTKSVKL
>Mature_306_residues
MENVTLSEIKRTPELLKQVESVPFKLEKGKRYLFVGCGSSYNLGYIAAEMLNKNGYEADVVTGGKIVALGDFPEADVAFF
ISRTGESTETVLAAKALKKRGIYTISIVCAKDAELSKTCEENIELPFADEESVVMTGSFSTILYMILRGIKRYSIDGIEG
FLGKSFEYVDRLELKKFSHFVFLGFDELYGLAKESALKVQEMALQWVEFHEPLDYRHGPKATLTEKTLVVMYSKDTAYEV
ELAKELKQMGAGVVYIGKEGDIEIPYQDGFETPVRILPVQYLAYKKAVSLGLNPDKPKNLTKSVKL

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Escherichia coli, GI1790167, Length=343, Percent_Identity=23.0320699708455, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357745, Length=331, Percent_Identity=23.5649546827795, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 34231; Mature: 34231

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENVTLSEIKRTPELLKQVESVPFKLEKGKRYLFVGCGSSYNLGYIAAEMLNKNGYEADV
CCCCCHHHHHCCHHHHHHHHHCCEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEE
VTGGKIVALGDFPEADVAFFISRTGESTETVLAAKALKKRGIYTISIVCAKDAELSKTCE
EECCEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHH
ENIELPFADEESVVMTGSFSTILYMILRGIKRYSIDGIEGFLGKSFEYVDRLELKKFSHF
HCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHCEE
VFLGFDELYGLAKESALKVQEMALQWVEFHEPLDYRHGPKATLTEKTLVVMYSKDTAYEV
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCEEEEEEECCCCCHH
ELAKELKQMGAGVVYIGKEGDIEIPYQDGFETPVRILPVQYLAYKKAVSLGLNPDKPKNL
HHHHHHHHHCCCEEEECCCCCEECCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCC
TKSVKL
HHCCCC
>Mature Secondary Structure
MENVTLSEIKRTPELLKQVESVPFKLEKGKRYLFVGCGSSYNLGYIAAEMLNKNGYEADV
CCCCCHHHHHCCHHHHHHHHHCCEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEE
VTGGKIVALGDFPEADVAFFISRTGESTETVLAAKALKKRGIYTISIVCAKDAELSKTCE
EECCEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHH
ENIELPFADEESVVMTGSFSTILYMILRGIKRYSIDGIEGFLGKSFEYVDRLELKKFSHF
HCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHCEE
VFLGFDELYGLAKESALKVQEMALQWVEFHEPLDYRHGPKATLTEKTLVVMYSKDTAYEV
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCEEEEEEECCCCCHH
ELAKELKQMGAGVVYIGKEGDIEIPYQDGFETPVRILPVQYLAYKKAVSLGLNPDKPKNL
HHHHHHHHHCCCEEEECCCCCEECCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCC
TKSVKL
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]