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The map label for this gene is lytT [H]

Identifier: 239617502

GI number: 239617502

Start: 1187538

End: 1188245

Strand: Reverse

Name: lytT [H]

Synonym: Kole_1118

Alternate gene names: 239617502

Gene position: 1188245-1187538 (Counterclockwise)

Preceding gene: 239617503

Following gene: 239617501

Centisome position: 51.62

GC content: 38.56

Gene sequence:

>708_bases
ATGAATATAAAAGCTATCGTTGTCGACGATGAAATAATCGCCAGGAAAGCAATTATCGAGCTTATCGAAGATTATCAAAA
TATTGAAGTGATGGGCGAAGCTTCTTCGGCGGAAGAGGCCCTGGACATAATTAAAACAAAAAAACCGAATGTTGTTTTTC
TCGATATCCAGCTTCCTGGATTCAATGGAGTTGAATTTGTTGAACTGTTGAATCGACTTGAAGAAAAGGTCCTTGTCGTT
TTCATATCTGCCTATGATGAATATGCTCTCGATGCTTTTGAAGTTGATGCAGTGGATTACCTGATGAAACCGGTAAGTCC
GGAAAGGTTCGCGGTAACAGTTGAACGCATCGAAAAGGTTCTGGCTAAAGAGGGAGTGCTGGAAAAAGTTCCGGTGAAAG
AAGATAATCTTCTTGAGATGGTTGATCTTGAAGAGATTTTCTATTTCGAGTCTATGGATAAAAAAGTTTATCTCCACACG
AAAGAAGATGAGCTTGAAGTTTATCGTTACAATCTCTCAGAATTAGAATCAAGTCTTCCATCTTTTTTTGCAAGAGTACA
TAAGTCATTTATTGTAAACCTAAAAAAAGTTAGACGTTTCTCCTCATGGCCAGGAAGCCGTTCATACTTTCTCACTCTTT
CCAATGGAAAGGAAATCCCGATAGGAAAGAACTACAAAAGTAAGATTAAGAAGCTCCTCCACCTCTAG

Upstream 100 bases:

>100_bases
GAAAAAGGTTAGTGAAATAAGCTAAGTATGCTTGAAGAAGGGAGGCATAGGCGTTTATTTCTCCGAGTTTTGAAATTGAA
AATCTAAACGCCAAAAGCTT

Downstream 100 bases:

>100_bases
CCCGCCTTTCACTCCAAAATCTGCGCCTTTTGCTCCAAAAGAATTGATCGTTCACAAATTCAATTAATAAAATTAAGATT
GCGGGTTTACTAATCTCAAT

Product: two component transcriptional regulator, LytTR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MNIKAIVVDDEIIARKAIIELIEDYQNIEVMGEASSAEEALDIIKTKKPNVVFLDIQLPGFNGVEFVELLNRLEEKVLVV
FISAYDEYALDAFEVDAVDYLMKPVSPERFAVTVERIEKVLAKEGVLEKVPVKEDNLLEMVDLEEIFYFESMDKKVYLHT
KEDELEVYRYNLSELESSLPSFFARVHKSFIVNLKKVRRFSSWPGSRSYFLTLSNGKEIPIGKNYKSKIKKLLHL

Sequences:

>Translated_235_residues
MNIKAIVVDDEIIARKAIIELIEDYQNIEVMGEASSAEEALDIIKTKKPNVVFLDIQLPGFNGVEFVELLNRLEEKVLVV
FISAYDEYALDAFEVDAVDYLMKPVSPERFAVTVERIEKVLAKEGVLEKVPVKEDNLLEMVDLEEIFYFESMDKKVYLHT
KEDELEVYRYNLSELESSLPSFFARVHKSFIVNLKKVRRFSSWPGSRSYFLTLSNGKEIPIGKNYKSKIKKLLHL
>Mature_235_residues
MNIKAIVVDDEIIARKAIIELIEDYQNIEVMGEASSAEEALDIIKTKKPNVVFLDIQLPGFNGVEFVELLNRLEEKVLVV
FISAYDEYALDAFEVDAVDYLMKPVSPERFAVTVERIEKVLAKEGVLEKVPVKEDNLLEMVDLEEIFYFESMDKKVYLHT
KEDELEVYRYNLSELESSLPSFFARVHKSFIVNLKKVRRFSSWPGSRSYFLTLSNGKEIPIGKNYKSKIKKLLHL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=242, Percent_Identity=30.1652892561983, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788724, Length=247, Percent_Identity=27.9352226720648, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1788222, Length=108, Percent_Identity=31.4814814814815, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788192, Length=106, Percent_Identity=33.0188679245283, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27164; Mature: 27164

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKAIVVDDEIIARKAIIELIEDYQNIEVMGEASSAEEALDIIKTKKPNVVFLDIQLPG
CCEEEEEECHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCCEEEEEEECCC
FNGVEFVELLNRLEEKVLVVFISAYDEYALDAFEVDAVDYLMKPVSPERFAVTVERIEKV
CCCHHHHHHHHHHHHHHEEEEEEHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LAKEGVLEKVPVKEDNLLEMVDLEEIFYFESMDKKVYLHTKEDELEVYRYNLSELESSLP
HHHCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHEEECHHHHHHHHH
SFFARVHKSFIVNLKKVRRFSSWPGSRSYFLTLSNGKEIPIGKNYKSKIKKLLHL
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MNIKAIVVDDEIIARKAIIELIEDYQNIEVMGEASSAEEALDIIKTKKPNVVFLDIQLPG
CCEEEEEECHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCCEEEEEEECCC
FNGVEFVELLNRLEEKVLVVFISAYDEYALDAFEVDAVDYLMKPVSPERFAVTVERIEKV
CCCHHHHHHHHHHHHHHEEEEEEHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LAKEGVLEKVPVKEDNLLEMVDLEEIFYFESMDKKVYLHTKEDELEVYRYNLSELESSLP
HHHCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHEEECHHHHHHHHH
SFFARVHKSFIVNLKKVRRFSSWPGSRSYFLTLSNGKEIPIGKNYKSKIKKLLHL
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]