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The map label for this gene is tldD [C]

Identifier: 239617394

GI number: 239617394

Start: 1062838

End: 1064229

Strand: Reverse

Name: tldD [C]

Synonym: Kole_1004

Alternate gene names: 239617394

Gene position: 1064229-1062838 (Counterclockwise)

Preceding gene: 239617396

Following gene: 239617393

Centisome position: 46.23

GC content: 44.47

Gene sequence:

>1392_bases
ATGTTAGAACTATTGAAATCCGTGGTACCGGCGGTTTCTTATCCGGTTCTTCTCAGATACCACGCCAGAACCTCTCGCGT
TTTTAGTTTCTCTAACGGGAAACTAAAAGAAGCATCCACGAAAAAACTAACAGGTGTCAGCGTCAGAGTTTGGTACGAAG
GAGTCTGGGGATTCGCCAGTACCAGCATCATGACAAAAGCCGGAATCTCAAAAGCCATTGAAAGTGCTATCGACGCTGCG
CGTAAAGGGAAAGGAGTTAAATCAGGAGAGATTTACAAACCTATCTTCAAACCTGCCAGAGGAGAGTTTAAGATCATTGA
AACTGACCCGGTTGAAAACCACACGGTTGATGAAAAGATAGACCTCGTCAGGAAAACGGTTGAAAGAATCAAGAACGTGA
GCGAAAAGATTGTTTCTTCCAGTTCAACCTATATGGAGCTTATCGACAATAAAACCATGGTTTCAAACTATGGCGTGGAA
GCAACCTATTATGATGTAAAAGCTGATTTCCGGGCTATTGCTTTTGCAAGTGACGGAAGTGAAATGGAGTTAGGTTATGC
AAGTTCCGGAGCCACTGGTGGTTGGGGAGAACTCTTCGGCGATAAATCATGGGAAGAAATGGCCGAAGAAGCTGCGAGAA
TTGCTCTGGATAAGCTCGGTAGAAAAACTCCAGAAGGTGGCATCTATACTGTTGTTTTACATCCATCTTTGGTGGGTGTG
CTTGCTCATGAGGCTATAGGGCATACGGTTGAAGCCGATTTTGTTCTTGCCGGATCCGCAGCTAAAGGGATGATAGGAAA
GAAAGTTGCAAGCGATCTCGTCACTTTGATAGATGACCCCAATCCAGAACTAAGAACCGGTGCCTCTGGAATAGTCTTGA
TAGATGATGAAGGAAACCTCACAAAAAAGATTTACGTAATAAGGAATGGAATTATGGAATCGTATCTCCACGATGCTGAA
ACAGCCGCTGTTTTTGGTGTCGAACCGACGGGAAATGCAAGAGCCTTCACTTATTCAGATGAACCTATAATCAGGATGAG
AAACACATACATAGCACCTGGTGAAACCCCTGTTGAAGAGATAATCGCGACCACAAAAGAAGGTTTATACCTCAAAGGAC
TCGGTGGCGGCGGCCAGGCAGATGCCAACGCAGAATTCATGTTTGGTGTTCTTGAAGCCTACGAAATAAAAAACGGAAAA
ATCGGGGAACCAGTGAAGGGAATAACCATCTCCGGGCAGGCTTTTGAAGTTCTTAAATCAGTAGATGCGGTTGGAAATGA
TTTTGAATTTACACTGGGAGCCGGATATTGTGGAAAATTCCAGCCTGCCAAGGTAGATGCTGGTGGCCCTCATATAAGGT
GTAAAGTCAAGATAGGAGGGGAACAAAAATGA

Upstream 100 bases:

>100_bases
AATCCTTTTAAGATATTTTAGTGGGTTACCAGTGTATTTAGTTCATACTGCGTATTATTATATAATGGATTTGTGTTAAT
GAATAAATGGAGGTGTAGAA

Downstream 100 bases:

>100_bases
GAGAAATAGTCAAAAAAGCTCTTGAACTGGCTAAAAATAAAAGCAAAGGAGATGCCGAGGTATGTTTTCAGCATACAAAA
AGAGCGAGAGTTTTCTTCGA

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MLELLKSVVPAVSYPVLLRYHARTSRVFSFSNGKLKEASTKKLTGVSVRVWYEGVWGFASTSIMTKAGISKAIESAIDAA
RKGKGVKSGEIYKPIFKPARGEFKIIETDPVENHTVDEKIDLVRKTVERIKNVSEKIVSSSSTYMELIDNKTMVSNYGVE
ATYYDVKADFRAIAFASDGSEMELGYASSGATGGWGELFGDKSWEEMAEEAARIALDKLGRKTPEGGIYTVVLHPSLVGV
LAHEAIGHTVEADFVLAGSAAKGMIGKKVASDLVTLIDDPNPELRTGASGIVLIDDEGNLTKKIYVIRNGIMESYLHDAE
TAAVFGVEPTGNARAFTYSDEPIIRMRNTYIAPGETPVEEIIATTKEGLYLKGLGGGGQADANAEFMFGVLEAYEIKNGK
IGEPVKGITISGQAFEVLKSVDAVGNDFEFTLGAGYCGKFQPAKVDAGGPHIRCKVKIGGEQK

Sequences:

>Translated_463_residues
MLELLKSVVPAVSYPVLLRYHARTSRVFSFSNGKLKEASTKKLTGVSVRVWYEGVWGFASTSIMTKAGISKAIESAIDAA
RKGKGVKSGEIYKPIFKPARGEFKIIETDPVENHTVDEKIDLVRKTVERIKNVSEKIVSSSSTYMELIDNKTMVSNYGVE
ATYYDVKADFRAIAFASDGSEMELGYASSGATGGWGELFGDKSWEEMAEEAARIALDKLGRKTPEGGIYTVVLHPSLVGV
LAHEAIGHTVEADFVLAGSAAKGMIGKKVASDLVTLIDDPNPELRTGASGIVLIDDEGNLTKKIYVIRNGIMESYLHDAE
TAAVFGVEPTGNARAFTYSDEPIIRMRNTYIAPGETPVEEIIATTKEGLYLKGLGGGGQADANAEFMFGVLEAYEIKNGK
IGEPVKGITISGQAFEVLKSVDAVGNDFEFTLGAGYCGKFQPAKVDAGGPHIRCKVKIGGEQK
>Mature_463_residues
MLELLKSVVPAVSYPVLLRYHARTSRVFSFSNGKLKEASTKKLTGVSVRVWYEGVWGFASTSIMTKAGISKAIESAIDAA
RKGKGVKSGEIYKPIFKPARGEFKIIETDPVENHTVDEKIDLVRKTVERIKNVSEKIVSSSSTYMELIDNKTMVSNYGVE
ATYYDVKADFRAIAFASDGSEMELGYASSGATGGWGELFGDKSWEEMAEEAARIALDKLGRKTPEGGIYTVVLHPSLVGV
LAHEAIGHTVEADFVLAGSAAKGMIGKKVASDLVTLIDDPNPELRTGASGIVLIDDEGNLTKKIYVIRNGIMESYLHDAE
TAAVFGVEPTGNARAFTYSDEPIIRMRNTYIAPGETPVEEIIATTKEGLYLKGLGGGGQADANAEFMFGVLEAYEIKNGK
IGEPVKGITISGQAFEVLKSVDAVGNDFEFTLGAGYCGKFQPAKVDAGGPHIRCKVKIGGEQK

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=448, Percent_Identity=32.3660714285714, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1790682, Length=392, Percent_Identity=21.6836734693878, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49822; Mature: 49822

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELLKSVVPAVSYPVLLRYHARTSRVFSFSNGKLKEASTKKLTGVSVRVWYEGVWGFAS
CHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCCCCCEECCEEEEEEEECCCCHHH
TSIMTKAGISKAIESAIDAARKGKGVKSGEIYKPIFKPARGEFKIIETDPVENHTVDEKI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCHHHHH
DLVRKTVERIKNVSEKIVSSSSTYMELIDNKTMVSNYGVEATYYDVKADFRAIAFASDGS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCCEEEEEEECCCEEEEEEECCCC
EMELGYASSGATGGWGELFGDKSWEEMAEEAARIALDKLGRKTPEGGIYTVVLHPSLVGV
CEEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHH
LAHEAIGHTVEADFVLAGSAAKGMIGKKVASDLVTLIDDPNPELRTGASGIVLIDDEGNL
HHHHHHCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEECCCCC
TKKIYVIRNGIMESYLHDAETAAVFGVEPTGNARAFTYSDEPIIRMRNTYIAPGETPVEE
EEEEEEEHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCEEEEECCEECCCCCCHHH
IIATTKEGLYLKGLGGGGQADANAEFMFGVLEAYEIKNGKIGEPVKGITISGQAFEVLKS
HHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCEEECCHHHHHHHH
VDAVGNDFEFTLGAGYCGKFQPAKVDAGGPHIRCKVKIGGEQK
HHHCCCCEEEEECCCCCCCCCCCEECCCCCEEEEEEEECCCCC
>Mature Secondary Structure
MLELLKSVVPAVSYPVLLRYHARTSRVFSFSNGKLKEASTKKLTGVSVRVWYEGVWGFAS
CHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCCCCCEECCEEEEEEEECCCCHHH
TSIMTKAGISKAIESAIDAARKGKGVKSGEIYKPIFKPARGEFKIIETDPVENHTVDEKI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCHHHHH
DLVRKTVERIKNVSEKIVSSSSTYMELIDNKTMVSNYGVEATYYDVKADFRAIAFASDGS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCCEEEEEEECCCEEEEEEECCCC
EMELGYASSGATGGWGELFGDKSWEEMAEEAARIALDKLGRKTPEGGIYTVVLHPSLVGV
CEEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHH
LAHEAIGHTVEADFVLAGSAAKGMIGKKVASDLVTLIDDPNPELRTGASGIVLIDDEGNL
HHHHHHCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEECCCCC
TKKIYVIRNGIMESYLHDAETAAVFGVEPTGNARAFTYSDEPIIRMRNTYIAPGETPVEE
EEEEEEEHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCEEEEECCEECCCCCCHHH
IIATTKEGLYLKGLGGGGQADANAEFMFGVLEAYEIKNGKIGEPVKGITISGQAFEVLKS
HHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCEEECCHHHHHHHH
VDAVGNDFEFTLGAGYCGKFQPAKVDAGGPHIRCKVKIGGEQK
HHHCCCCEEEEECCCCCCCCCCCEECCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]