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The map label for this gene is pmbA [C]

Identifier: 239617393

GI number: 239617393

Start: 1061507

End: 1062841

Strand: Reverse

Name: pmbA [C]

Synonym: Kole_1003

Alternate gene names: 239617393

Gene position: 1062841-1061507 (Counterclockwise)

Preceding gene: 239617394

Following gene: 239617392

Centisome position: 46.17

GC content: 44.19

Gene sequence:

>1335_bases
ATGAGAGAAATAGTCAAAAAAGCTCTTGAACTGGCTAAAAATAAAAGCAAAGGAGATGCCGAGGTATGTTTTCAGCATAC
AAAAAGAGCGAGAGTTTTCTTCGAGAAAAATGAACTCAAAACACTGCACGAAGACGAATCAAGCGGAATCGGCGTAAGGG
TTGTAAAAGATGGAAAACTCGGCTTTGGGGCCTCCAATACCATCGAGGAAGACGACCTGGCGGTTCTTATCGATGATGCT
GTTAGCGCTATGGAAAAATCTAAAGCGGATCCCGGAAACGTATTACCAGATCCTGCCGAAATAAAAGAAATCCCAGGTTT
ATATTCTAAAGAACTTAGCGAATATAACCTTCCAAAGGTTCTGGAATTCGGTAAAATGCTGTTTGAAACTGTAAAGAAGA
TCGATTCCAGGATTACGATAGATTCCGCTCAGGTCCAGCTAACAGTGACCGATTCCCACCTTGTAAACTCCAGAGGTATC
AGCGCCACCAAAAGCAAATCCTCCCTGTCATACGTAATAATGGGAATGGCAATCGACGGGAACGATATTTCCTCTTTTGA
CTACCGTTATGGAATGATTCTGAATCCTGAAGAAATAGAATCAAAACTTCAAGAAGCCGCTCAGAGCTTTGCAAACAGTG
TTCTTGGCTCACTGGGTGCCAAACCGTGTAACTCCTTCAAAGGGCTTGCACTCTTGAGTCCCTCCACCGTCGAAAGGCTT
ATAATTATGCCCCTCAGTTTCTTACTTAGCGGTGAAAACATCCTGGAAAACCGCAGTCCTTTCAAAGAAAAAATCGGGGA
GAAAATTGCGGGGGAAAATCTGACCATATACGACGATCCCACCATTCCATATAATCCCTATTCCACACCTTTTGACAGAG
AAGGCGTCCCGACAAAACGCTTGACCCTCATCAAAAATGGTGTTCTGAAAACATTCATCCACAATGCGTATTCCGCAACG
CTTCTTAAGGCACCGATGACAGGACATGCCACAGGGGATTACTCCAGCCTCCCGGAAATAAGCATCTACAACGCTGTCGT
TGAAGGTGAAATACCCCTCGATGATATCTACAAAATGATCGATAAGGGTGTATATGTGAATAGATTCAGCGGAAATATAA
ATCCCGTGAACGGGTTGTTCTCCGGCGCTGTTAAAGGAGGCTGGTATCTGGAAAACGGTAACAGAATTCACCCGGTAACG
GGAACACTCGTATCTGGAAACGCACTGGAGCTGCTGAACCATATCGTGGCTGTTTCAAGAGAAAGAGAACAAACAACAAT
GGGAGAACTTCCTTATATTCTGGTTGACACCGTCTCTTTCACCGGGAAACAATAA

Upstream 100 bases:

>100_bases
TTACACTGGGAGCCGGATATTGTGGAAAATTCCAGCCTGCCAAGGTAGATGCTGGTGGCCCTCATATAAGGTGTAAAGTC
AAGATAGGAGGGGAACAAAA

Downstream 100 bases:

>100_bases
CAACAAAAGAAAATAATATAGGAAACCGGAGAACCAGGGAACCAGAGAAGGTTCTCTGGTTTTTACTTTTCTGAACAATA
ACCAATAGCGAAAATGACTA

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MREIVKKALELAKNKSKGDAEVCFQHTKRARVFFEKNELKTLHEDESSGIGVRVVKDGKLGFGASNTIEEDDLAVLIDDA
VSAMEKSKADPGNVLPDPAEIKEIPGLYSKELSEYNLPKVLEFGKMLFETVKKIDSRITIDSAQVQLTVTDSHLVNSRGI
SATKSKSSLSYVIMGMAIDGNDISSFDYRYGMILNPEEIESKLQEAAQSFANSVLGSLGAKPCNSFKGLALLSPSTVERL
IIMPLSFLLSGENILENRSPFKEKIGEKIAGENLTIYDDPTIPYNPYSTPFDREGVPTKRLTLIKNGVLKTFIHNAYSAT
LLKAPMTGHATGDYSSLPEISIYNAVVEGEIPLDDIYKMIDKGVYVNRFSGNINPVNGLFSGAVKGGWYLENGNRIHPVT
GTLVSGNALELLNHIVAVSREREQTTMGELPYILVDTVSFTGKQ

Sequences:

>Translated_444_residues
MREIVKKALELAKNKSKGDAEVCFQHTKRARVFFEKNELKTLHEDESSGIGVRVVKDGKLGFGASNTIEEDDLAVLIDDA
VSAMEKSKADPGNVLPDPAEIKEIPGLYSKELSEYNLPKVLEFGKMLFETVKKIDSRITIDSAQVQLTVTDSHLVNSRGI
SATKSKSSLSYVIMGMAIDGNDISSFDYRYGMILNPEEIESKLQEAAQSFANSVLGSLGAKPCNSFKGLALLSPSTVERL
IIMPLSFLLSGENILENRSPFKEKIGEKIAGENLTIYDDPTIPYNPYSTPFDREGVPTKRLTLIKNGVLKTFIHNAYSAT
LLKAPMTGHATGDYSSLPEISIYNAVVEGEIPLDDIYKMIDKGVYVNRFSGNINPVNGLFSGAVKGGWYLENGNRIHPVT
GTLVSGNALELLNHIVAVSREREQTTMGELPYILVDTVSFTGKQ
>Mature_444_residues
MREIVKKALELAKNKSKGDAEVCFQHTKRARVFFEKNELKTLHEDESSGIGVRVVKDGKLGFGASNTIEEDDLAVLIDDA
VSAMEKSKADPGNVLPDPAEIKEIPGLYSKELSEYNLPKVLEFGKMLFETVKKIDSRITIDSAQVQLTVTDSHLVNSRGI
SATKSKSSLSYVIMGMAIDGNDISSFDYRYGMILNPEEIESKLQEAAQSFANSVLGSLGAKPCNSFKGLALLSPSTVERL
IIMPLSFLLSGENILENRSPFKEKIGEKIAGENLTIYDDPTIPYNPYSTPFDREGVPTKRLTLIKNGVLKTFIHNAYSAT
LLKAPMTGHATGDYSSLPEISIYNAVVEGEIPLDDIYKMIDKGVYVNRFSGNINPVNGLFSGAVKGGWYLENGNRIHPVT
GTLVSGNALELLNHIVAVSREREQTTMGELPYILVDTVSFTGKQ

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790682, Length=453, Percent_Identity=23.3995584988962, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789640, Length=176, Percent_Identity=27.8409090909091, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 48666; Mature: 48666

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIVKKALELAKNKSKGDAEVCFQHTKRARVFFEKNELKTLHEDESSGIGVRVVKDGKL
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEECCHHHHHHCCCCCCCEEEEEECCCC
GFGASNTIEEDDLAVLIDDAVSAMEKSKADPGNVLPDPAEIKEIPGLYSKELSEYNLPKV
CCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCHHH
LEFGKMLFETVKKIDSRITIDSAQVQLTVTDSHLVNSRGISATKSKSSLSYVIMGMAIDG
HHHHHHHHHHHHHHHCEEEEECCEEEEEEECCHHHCCCCCCCCCCCCCCEEEEEEEEECC
NDISSFDYRYGMILNPEEIESKLQEAAQSFANSVLGSLGAKPCNSFKGLALLSPSTVERL
CCCCCCCEEECEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHH
IIMPLSFLLSGENILENRSPFKEKIGEKIAGENLTIYDDPTIPYNPYSTPFDREGVPTKR
HHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHH
LTLIKNGVLKTFIHNAYSATLLKAPMTGHATGDYSSLPEISIYNAVVEGEIPLDDIYKMI
HHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEHEEEECCCCHHHHHHHH
DKGVYVNRFSGNINPVNGLFSGAVKGGWYLENGNRIHPVTGTLVSGNALELLNHIVAVSR
HCCEEEEECCCCCCCHHHHHHHCCCCCEEECCCCEECCCCCEEECCCHHHHHHHHHHHHC
EREQTTMGELPYILVDTVSFTGKQ
HHHHHHHCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MREIVKKALELAKNKSKGDAEVCFQHTKRARVFFEKNELKTLHEDESSGIGVRVVKDGKL
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEECCHHHHHHCCCCCCCEEEEEECCCC
GFGASNTIEEDDLAVLIDDAVSAMEKSKADPGNVLPDPAEIKEIPGLYSKELSEYNLPKV
CCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCHHH
LEFGKMLFETVKKIDSRITIDSAQVQLTVTDSHLVNSRGISATKSKSSLSYVIMGMAIDG
HHHHHHHHHHHHHHHCEEEEECCEEEEEEECCHHHCCCCCCCCCCCCCCEEEEEEEEECC
NDISSFDYRYGMILNPEEIESKLQEAAQSFANSVLGSLGAKPCNSFKGLALLSPSTVERL
CCCCCCCEEECEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHH
IIMPLSFLLSGENILENRSPFKEKIGEKIAGENLTIYDDPTIPYNPYSTPFDREGVPTKR
HHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHH
LTLIKNGVLKTFIHNAYSATLLKAPMTGHATGDYSSLPEISIYNAVVEGEIPLDDIYKMI
HHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEHEEEECCCCHHHHHHHH
DKGVYVNRFSGNINPVNGLFSGAVKGGWYLENGNRIHPVTGTLVSGNALELLNHIVAVSR
HCCEEEEECCCCCCCHHHHHHHCCCCCEEECCCCEECCCCCEEECCCHHHHHHHHHHHHC
EREQTTMGELPYILVDTVSFTGKQ
HHHHHHHCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]