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The map label for this gene is rpfG [H]

Identifier: 239617237

GI number: 239617237

Start: 892466

End: 893953

Strand: Direct

Name: rpfG [H]

Synonym: Kole_0845

Alternate gene names: 239617237

Gene position: 892466-893953 (Clockwise)

Preceding gene: 239617236

Following gene: 239617238

Centisome position: 38.77

GC content: 38.58

Gene sequence:

>1488_bases
ATGCCGGATACAATAGGTAAAAATACCCGTGATTTCATTCAGCAATTTCATCAACTATTTATTGAACTTTGCGAAGTTAT
GCCAAACAGTTTCAACGATCTTATAACCGAAGCACTTAAGAGAACAACTGATTTTCTTGAAGTTATAGAGGTTTCAATTG
CTTTTGAAGAAGAAAACGGGTTAAAGATTTTAACCTCCAATAATACGAAAGAACTCTTACAAACTTACCAGAACGAGGCA
CTCCAGAAACTTGTTTTTACCGATAACGGAATGAAGAAGTTGGCCATAGAAAAAGCGAAAAAACTCATGCCATGGCTCAC
ACATTCCGGGGGCACACTTTGCATTGTGCCGCTAAACACCGTAAAAAATAAACTTGCCTTCATATACATTTTGATGGATA
ATTTTTCAGAAAGTGTGGAGTTTAATCCGCAGTTCGTTGAATATATAAGCCTGTTTTTTTCCACTCTGCTGCTCTTCTCA
AGAATCGGGGGTATAAAAGATTTGATTGAAACCATATTTACTCAGAGTCCTCACCCAATGTGGTTACAGAATAAATCAGG
AGAGTTTCTACTTTTCAACAACAGGTTCCTGAAACTCTTAAAAAAATCCAGAAACGAGTTGAAGGGAAAGAAACCCGCTG
AAATACTTTCCGGCAAGGACATAAACATATTTTATGAAATATTTGAGCAAGCACTCAGGGAGAAAAAAACTATCACAAAA
GAATGGATAACAGAGACTTCTGGAATTCCTAAAGCTTACCAACTGATAGAAGTCCCTTTTAAACTGGGTAACGATTATTT
CGTCACCGGTATTTGTGTAAATAAAGAACAACAGGAAAAACTCAAGCGCGAAAATGCTCAGCTTAAGAATGCTCTTGTTA
ATAGCCTCGCAATTCAAGCTGAAAATGTTCTGGAACAGGCAGATTTACATCTCGAACTGATATCCGAATGCTCGGCGATT
ATAGCTTTCCAACTTAAAGAGACGGGATATAATATAGACTCAGCCTTTCTTGCCAACATCCGGCTTGCTTCAAAGCTTCA
CGATATTGGGTTCCAGAAAATCCCGGAGAATATACTGAGAAAACCAGTCAAACTAAACCCAAACGAATGGCAGCTGCTGA
AAAAACATACTATTGCCGGTGCTGAATTCTTGCGCAAGCTCCGCGAAGAAAACTGCCCTCAAAACCTTCTCTTAAAGATG
GCCGAAAGCATCGCCCTAAACCACCACGAGTGGTATGATGGAAGTGGTTATCCATGTTCTTTAATTAGAGAAGAAATCCC
TTTAGAAGCAAGAATCATTGCCATTGCAGATACTTACAGCGCTTTAAGGGTTGATAGACCTTACCGAAAAGCGAAAACAC
ATCCTGAAACCCTTGAGATAATAAAAAATGAGGAAGGAACGCATTTTGATCCAGAAATCGTTGAAGCGTTTATGAAGGTA
GAAAGCGAAATAGAAGCATTGTTTGAAAGAATGCTTGAACAGTATTGA

Upstream 100 bases:

>100_bases
CTTGGGAACATCGAATCTGAAAATTTCGGTATATCCGTTGAAACAACCAGAAAAGACCGACATACTAAAGGATAAAGCCT
TTTTATGGAGGGTGTTGCAA

Downstream 100 bases:

>100_bases
CAACGTTATTACATATTTAGTAAAGGGGGAATTTTTGTGGGAAAACTTGACGGTACCAGAACACTTGAAAACCTTATGAA
AGCTTTTGCTGGAGAATCTC

Product: PAS/PAC sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MPDTIGKNTRDFIQQFHQLFIELCEVMPNSFNDLITEALKRTTDFLEVIEVSIAFEEENGLKILTSNNTKELLQTYQNEA
LQKLVFTDNGMKKLAIEKAKKLMPWLTHSGGTLCIVPLNTVKNKLAFIYILMDNFSESVEFNPQFVEYISLFFSTLLLFS
RIGGIKDLIETIFTQSPHPMWLQNKSGEFLLFNNRFLKLLKKSRNELKGKKPAEILSGKDINIFYEIFEQALREKKTITK
EWITETSGIPKAYQLIEVPFKLGNDYFVTGICVNKEQQEKLKRENAQLKNALVNSLAIQAENVLEQADLHLELISECSAI
IAFQLKETGYNIDSAFLANIRLASKLHDIGFQKIPENILRKPVKLNPNEWQLLKKHTIAGAEFLRKLREENCPQNLLLKM
AESIALNHHEWYDGSGYPCSLIREEIPLEARIIAIADTYSALRVDRPYRKAKTHPETLEIIKNEEGTHFDPEIVEAFMKV
ESEIEALFERMLEQY

Sequences:

>Translated_495_residues
MPDTIGKNTRDFIQQFHQLFIELCEVMPNSFNDLITEALKRTTDFLEVIEVSIAFEEENGLKILTSNNTKELLQTYQNEA
LQKLVFTDNGMKKLAIEKAKKLMPWLTHSGGTLCIVPLNTVKNKLAFIYILMDNFSESVEFNPQFVEYISLFFSTLLLFS
RIGGIKDLIETIFTQSPHPMWLQNKSGEFLLFNNRFLKLLKKSRNELKGKKPAEILSGKDINIFYEIFEQALREKKTITK
EWITETSGIPKAYQLIEVPFKLGNDYFVTGICVNKEQQEKLKRENAQLKNALVNSLAIQAENVLEQADLHLELISECSAI
IAFQLKETGYNIDSAFLANIRLASKLHDIGFQKIPENILRKPVKLNPNEWQLLKKHTIAGAEFLRKLREENCPQNLLLKM
AESIALNHHEWYDGSGYPCSLIREEIPLEARIIAIADTYSALRVDRPYRKAKTHPETLEIIKNEEGTHFDPEIVEAFMKV
ESEIEALFERMLEQY
>Mature_494_residues
PDTIGKNTRDFIQQFHQLFIELCEVMPNSFNDLITEALKRTTDFLEVIEVSIAFEEENGLKILTSNNTKELLQTYQNEAL
QKLVFTDNGMKKLAIEKAKKLMPWLTHSGGTLCIVPLNTVKNKLAFIYILMDNFSESVEFNPQFVEYISLFFSTLLLFSR
IGGIKDLIETIFTQSPHPMWLQNKSGEFLLFNNRFLKLLKKSRNELKGKKPAEILSGKDINIFYEIFEQALREKKTITKE
WITETSGIPKAYQLIEVPFKLGNDYFVTGICVNKEQQEKLKRENAQLKNALVNSLAIQAENVLEQADLHLELISECSAII
AFQLKETGYNIDSAFLANIRLASKLHDIGFQKIPENILRKPVKLNPNEWQLLKKHTIAGAEFLRKLREENCPQNLLLKMA
ESIALNHHEWYDGSGYPCSLIREEIPLEARIIAIADTYSALRVDRPYRKAKTHPETLEIIKNEEGTHFDPEIVEAFMKVE
SEIEALFERMLEQY

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: COG2206

COG function: function code T; HD-GYP domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 57114; Mature: 56983

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTIGKNTRDFIQQFHQLFIELCEVMPNSFNDLITEALKRTTDFLEVIEVSIAFEEENG
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
LKILTSNNTKELLQTYQNEALQKLVFTDNGMKKLAIEKAKKLMPWLTHSGGTLCIVPLNT
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHH
VKNKLAFIYILMDNFSESVEFNPQFVEYISLFFSTLLLFSRIGGIKDLIETIFTQSPHPM
HHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
WLQNKSGEFLLFNNRFLKLLKKSRNELKGKKPAEILSGKDINIFYEIFEQALREKKTITK
EEECCCCCEEEECHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EWITETSGIPKAYQLIEVPFKLGNDYFVTGICVNKEQQEKLKRENAQLKNALVNSLAIQA
HHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
ENVLEQADLHLELISECSAIIAFQLKETGYNIDSAFLANIRLASKLHDIGFQKIPENILR
HHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHC
KPVKLNPNEWQLLKKHTIAGAEFLRKLREENCPQNLLLKMAESIALNHHEWYDGSGYPCS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHH
LIREEIPLEARIIAIADTYSALRVDRPYRKAKTHPETLEIIKNEEGTHFDPEIVEAFMKV
HHHHHCCCCEEEEEEECCHHHHHCCCCHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHH
ESEIEALFERMLEQY
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDTIGKNTRDFIQQFHQLFIELCEVMPNSFNDLITEALKRTTDFLEVIEVSIAFEEENG
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
LKILTSNNTKELLQTYQNEALQKLVFTDNGMKKLAIEKAKKLMPWLTHSGGTLCIVPLNT
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHH
VKNKLAFIYILMDNFSESVEFNPQFVEYISLFFSTLLLFSRIGGIKDLIETIFTQSPHPM
HHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
WLQNKSGEFLLFNNRFLKLLKKSRNELKGKKPAEILSGKDINIFYEIFEQALREKKTITK
EEECCCCCEEEECHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EWITETSGIPKAYQLIEVPFKLGNDYFVTGICVNKEQQEKLKRENAQLKNALVNSLAIQA
HHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
ENVLEQADLHLELISECSAIIAFQLKETGYNIDSAFLANIRLASKLHDIGFQKIPENILR
HHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHC
KPVKLNPNEWQLLKKHTIAGAEFLRKLREENCPQNLLLKMAESIALNHHEWYDGSGYPCS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHH
LIREEIPLEARIIAIADTYSALRVDRPYRKAKTHPETLEIIKNEEGTHFDPEIVEAFMKV
HHHHHCCCCEEEEEEECCHHHHHCCCCHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHH
ESEIEALFERMLEQY
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]