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The map label for this gene is yokL [H]

Identifier: 239617210

GI number: 239617210

Start: 868240

End: 868779

Strand: Direct

Name: yokL [H]

Synonym: Kole_0817

Alternate gene names: 239617210

Gene position: 868240-868779 (Clockwise)

Preceding gene: 239617208

Following gene: 239617211

Centisome position: 37.71

GC content: 40.0

Gene sequence:

>540_bases
ATGCTTGAGGGAAAATCTGTCAGGCTAAGGGCTTACAGAAAAGAAGATGTTGAATTAGCATGGAAGTACATCAACGATCC
TGAAGTGAAAAGTTATTTGGTTCCAGGAATACCCTTTCCCATGACTCTGGAAGAAGAGTACAAATGGTATGAAAACTTGA
GTTCTTCGAAGGATACCTATAACTTCGCCATAGAAAGGATAGAGGATGGTCAGTATATAGGTGGCTGCGGAATCAACGAA
GTCAACTGGAAGAACAGCTACGCTTACGTCGGGATCTTTCTGGGTAAACCTTACTGGTCTAAGGGTTACGGTACAGAAGC
CATGAAATTGCTGCTCAGATTCATTTTTGAAGAGATGAACCTTAATAAAGTGCTCTTAAATGTCTATTCCTTCAACGAGC
GCGCTATAAGAAGCTATGAAAAATGCGGGTTCGTAGTAGAAGGCCGTTTGAGAGAGCAGATTTTTAGAAAAGGAAAATAC
TACGACGAAATAATTATGGGGATTTTAAGGCGAGAATTTCTAAGAACTATCTCTGATTAA

Upstream 100 bases:

>100_bases
GATATAATTTTGAAAACCCAATTCAGATAATAGACCTTTCCATTCCAAAACCATTCAACAGAAGTGAAATACTGTCTATA
GCTGGTAGAGGGGGGAGAGA

Downstream 100 bases:

>100_bases
CAAATAGGAGGTGTCGCCCAATTGAAAGTATTTCTGGTAGTTTCCCTTCTATTACTTTCAATAAGCATATTTGCTTTGAA
CAAACCTATAGCTCTACTTT

Product: GCN5-related N-acetyltransferase

Products: Coenzyme A; H+; N8-Acetylspermidine [C]

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MLEGKSVRLRAYRKEDVELAWKYINDPEVKSYLVPGIPFPMTLEEEYKWYENLSSSKDTYNFAIERIEDGQYIGGCGINE
VNWKNSYAYVGIFLGKPYWSKGYGTEAMKLLLRFIFEEMNLNKVLLNVYSFNERAIRSYEKCGFVVEGRLREQIFRKGKY
YDEIIMGILRREFLRTISD

Sequences:

>Translated_179_residues
MLEGKSVRLRAYRKEDVELAWKYINDPEVKSYLVPGIPFPMTLEEEYKWYENLSSSKDTYNFAIERIEDGQYIGGCGINE
VNWKNSYAYVGIFLGKPYWSKGYGTEAMKLLLRFIFEEMNLNKVLLNVYSFNERAIRSYEKCGFVVEGRLREQIFRKGKY
YDEIIMGILRREFLRTISD
>Mature_179_residues
MLEGKSVRLRAYRKEDVELAWKYINDPEVKSYLVPGIPFPMTLEEEYKWYENLSSSKDTYNFAIERIEDGQYIGGCGINE
VNWKNSYAYVGIFLGKPYWSKGYGTEAMKLLLRFIFEEMNLNKVLLNVYSFNERAIRSYEKCGFVVEGRLREQIFRKGKY
YDEIIMGILRREFLRTISD

Specific function: Regulates Polyamine Concentration By Their Degradation. Acts On Spermidine, Forming N(1)- And N(8)-Acetylspermidine. [C]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1787867, Length=181, Percent_Identity=31.4917127071823, Blast_Score=74, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: 2.3.1.57 [C]

Molecular weight: Translated: 21265; Mature: 21265

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEGKSVRLRAYRKEDVELAWKYINDPEVKSYLVPGIPFPMTLEEEYKWYENLSSSKDTY
CCCCCCEEEEEHHHHCHHHHHHHCCCCCHHHEECCCCCCCCCHHHHHHHHHHCCCCCCHH
NFAIERIEDGQYIGGCGINEVNWKNSYAYVGIFLGKPYWSKGYGTEAMKLLLRFIFEEMN
HHHHEEECCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
LNKVLLNVYSFNERAIRSYEKCGFVVEGRLREQIFRKGKYYDEIIMGILRREFLRTISD
HHHHHHHHHHCCHHHHHHHHHCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEGKSVRLRAYRKEDVELAWKYINDPEVKSYLVPGIPFPMTLEEEYKWYENLSSSKDTY
CCCCCCEEEEEHHHHCHHHHHHHCCCCCHHHEECCCCCCCCCHHHHHHHHHHCCCCCCHH
NFAIERIEDGQYIGGCGINEVNWKNSYAYVGIFLGKPYWSKGYGTEAMKLLLRFIFEEMN
HHHHEEECCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
LNKVLLNVYSFNERAIRSYEKCGFVVEGRLREQIFRKGKYYDEIIMGILRREFLRTISD
HHHHHHHHHHCCHHHHHHHHHCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Spermidine [C]

Specific reaction: Acetyl-CoA + Spermidine --> Coenzyme A + H+ + N8-Acetylspermidine [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]