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The map label for this gene is cobP [H]

Identifier: 239616859

GI number: 239616859

Start: 484152

End: 484640

Strand: Direct

Name: cobP [H]

Synonym: Kole_0454

Alternate gene names: 239616859

Gene position: 484152-484640 (Clockwise)

Preceding gene: 239616858

Following gene: 239616860

Centisome position: 21.03

GC content: 43.76

Gene sequence:

>489_bases
ATGATCTTAATTACAGGAGGAGAACGCTCAGGAAAAAGCCGCCTTGCACTGGAACTGGCGTTAAAAAAAGGAGAAAAAAG
GGCATTTATCGCAACAGCTGAAGCCATAGATGAGGAAATGAGTTCGCGTATAGCAAAACACAAAGAAGAGCGGGGGAACC
TGTTCGTTACATACGAAGAACCGCTGGATATACACGAGATCCTGAAAAAAACAGGGGATTACGACGTTGTTGTGGTGGAA
TGTATGACAACGTGGTTGGGGAATCTTTTTCACTACGGTCGAAATATCGATGAGATGGTTGAAAAGTTTATCGGCAGTAT
CAATGGAAATGAGATAATCGTAAGCAATGAAATAGGCATGGGGGTGATACCGGAAAACCCGATCACCCGGACTTTTGTGG
AAGCGCTCGGAAGGCTAAACGCAAGAATCGCGCAGATAGCAGATGAGGTTTACTTTGTAGTTACAGGGATAGGTGTAAAG
ATAAAATGA

Upstream 100 bases:

>100_bases
CAGGGGCTGTGCTTTCTTTCTCGATCATAGAAGCAGCCATTAAGATGATCAATGAAATGGCAACCTTTGATGATGCGAAC
GTTTCAAAGGGGAAAGAAAA

Downstream 100 bases:

>100_bases
TAGGTTCCACATCATGGGTAATTCCCGGAACTTATTACGAAAACGCTTTACTCCTCGAAGGGCTCGTAGACTTCGTGGAG
CTGTTGGTTTATACGTGGGA

Product: Adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MILITGGERSGKSRLALELALKKGEKRAFIATAEAIDEEMSSRIAKHKEERGNLFVTYEEPLDIHEILKKTGDYDVVVVE
CMTTWLGNLFHYGRNIDEMVEKFIGSINGNEIIVSNEIGMGVIPENPITRTFVEALGRLNARIAQIADEVYFVVTGIGVK
IK

Sequences:

>Translated_162_residues
MILITGGERSGKSRLALELALKKGEKRAFIATAEAIDEEMSSRIAKHKEERGNLFVTYEEPLDIHEILKKTGDYDVVVVE
CMTTWLGNLFHYGRNIDEMVEKFIGSINGNEIIVSNEIGMGVIPENPITRTFVEALGRLNARIAQIADEVYFVVTGIGVK
IK
>Mature_162_residues
MILITGGERSGKSRLALELALKKGEKRAFIATAEAIDEEMSSRIAKHKEERGNLFVTYEEPLDIHEILKKTGDYDVVVVE
CMTTWLGNLFHYGRNIDEMVEKFIGSINGNEIIVSNEIGMGVIPENPITRTFVEALGRLNARIAQIADEVYFVVTGIGVK
IK

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=37.0165745856354, Blast_Score=110, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18069; Mature: 18069

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILITGGERSGKSRLALELALKKGEKRAFIATAEAIDEEMSSRIAKHKEERGNLFVTYEE
CEEEECCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
PLDIHEILKKTGDYDVVVVECMTTWLGNLFHYGRNIDEMVEKFIGSINGNEIIVSNEIGM
CCCHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCC
GVIPENPITRTFVEALGRLNARIAQIADEVYFVVTGIGVKIK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEC
>Mature Secondary Structure
MILITGGERSGKSRLALELALKKGEKRAFIATAEAIDEEMSSRIAKHKEERGNLFVTYEE
CEEEECCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
PLDIHEILKKTGDYDVVVVECMTTWLGNLFHYGRNIDEMVEKFIGSINGNEIIVSNEIGM
CCCHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCC
GVIPENPITRTFVEALGRLNARIAQIADEVYFVVTGIGVKIK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]