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The map label for this gene is cobT [H]

Identifier: 239616858

GI number: 239616858

Start: 483133

End: 484155

Strand: Direct

Name: cobT [H]

Synonym: Kole_0453

Alternate gene names: 239616858

Gene position: 483133-484155 (Clockwise)

Preceding gene: 239616857

Following gene: 239616859

Centisome position: 20.99

GC content: 42.33

Gene sequence:

>1023_bases
ATGGCAAAAAAAGATCTTGAAAACAAAATAAAAGAAAGACTGAATAGCCTGACAAAACCGAAAGGAAGCCTTGGCTTCCT
CGAGGATATAGCATTAAAGATGGGAAAAATACAGGGAAAAGTCCTTCCAAACCTACCGGAGAAAAAAGCGGTTTTTGTCT
TCGCAGGAGACCACGGTGTTACTGAAGAAGGAGTATCCGCATATCCAAAAGAAGTAACGGCACAGATGGTGTTGAACTTC
CTGAATGGTGGAGCAGCGATAAATGTTTTTTCGCGGCATGTTGGAAGTGAAGTTTATGTTATTGACGCAGGGGTTGATTA
TGATTTTCCTGCACATGAAAGGCTTTTGAATAAGAAAGTTGGAAAAGGCACCAAAAATTTTTCTAAAGAACCTGCGATGA
CCAGGGAAGAAGCAGAAAAATCGATAGAATATGGAAAAGAAATAGCACGCTTCGCAAAAGAGAAAGGATTTGAACTCGTT
GCAGTGGGAGATATGGGAATAGGAAACACAACAACCGCAACCACTATTGCCATAGCATTGGGACATAACCTTTCAGAACT
GATAGACATTGGAACGGTTATAACCGGGCAACAATTGGAGAAGAAAGAGGCAGTGGTAAGACAAGCTATTTCAATTCACG
AACCATTTATGGATCCCATTGATGTCTTATCGAAAGTAGGCAGCTATTGTCTGGGAGAAATGGCGGGATTTATACTCGAG
TGCGCACAATTAAATATTCCTGTAGTTATAGATGGGTTCCCAACCACAGCGGCTGCCCTCATTGCAGCGCAATTGAATCC
TGAAGTCCTTGACTGTATGTTTGCCGGGCATTGTTCAAAGGTTAAGGGCCATAGAGTATTGCTCGATGCTCTCAATCTAC
GCCCTATCCTGGATCTTGATATGCGTCTCGGTGAAGGAACAGGGGCTGTGCTTTCTTTCTCGATCATAGAAGCAGCCATT
AAGATGATCAATGAAATGGCAACCTTTGATGATGCGAACGTTTCAAAGGGGAAAGAAAAATGA

Upstream 100 bases:

>100_bases
CAAGGTTATTCATGGAGTTCATGCAAAGTTTGGAAGACTCTGAAAAATCTGATAGAAATTCTGATAAAGATAAAAGTTAT
CATGAGTAAGGAGGTAAAAA

Downstream 100 bases:

>100_bases
TCTTAATTACAGGAGGAGAACGCTCAGGAAAAAGCCGCCTTGCACTGGAACTGGCGTTAAAAAAAGGAGAAAAAAGGGCA
TTTATCGCAACAGCTGAAGC

Product: nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MAKKDLENKIKERLNSLTKPKGSLGFLEDIALKMGKIQGKVLPNLPEKKAVFVFAGDHGVTEEGVSAYPKEVTAQMVLNF
LNGGAAINVFSRHVGSEVYVIDAGVDYDFPAHERLLNKKVGKGTKNFSKEPAMTREEAEKSIEYGKEIARFAKEKGFELV
AVGDMGIGNTTTATTIAIALGHNLSELIDIGTVITGQQLEKKEAVVRQAISIHEPFMDPIDVLSKVGSYCLGEMAGFILE
CAQLNIPVVIDGFPTTAAALIAAQLNPEVLDCMFAGHCSKVKGHRVLLDALNLRPILDLDMRLGEGTGAVLSFSIIEAAI
KMINEMATFDDANVSKGKEK

Sequences:

>Translated_340_residues
MAKKDLENKIKERLNSLTKPKGSLGFLEDIALKMGKIQGKVLPNLPEKKAVFVFAGDHGVTEEGVSAYPKEVTAQMVLNF
LNGGAAINVFSRHVGSEVYVIDAGVDYDFPAHERLLNKKVGKGTKNFSKEPAMTREEAEKSIEYGKEIARFAKEKGFELV
AVGDMGIGNTTTATTIAIALGHNLSELIDIGTVITGQQLEKKEAVVRQAISIHEPFMDPIDVLSKVGSYCLGEMAGFILE
CAQLNIPVVIDGFPTTAAALIAAQLNPEVLDCMFAGHCSKVKGHRVLLDALNLRPILDLDMRLGEGTGAVLSFSIIEAAI
KMINEMATFDDANVSKGKEK
>Mature_339_residues
AKKDLENKIKERLNSLTKPKGSLGFLEDIALKMGKIQGKVLPNLPEKKAVFVFAGDHGVTEEGVSAYPKEVTAQMVLNFL
NGGAAINVFSRHVGSEVYVIDAGVDYDFPAHERLLNKKVGKGTKNFSKEPAMTREEAEKSIEYGKEIARFAKEKGFELVA
VGDMGIGNTTTATTIAIALGHNLSELIDIGTVITGQQLEKKEAVVRQAISIHEPFMDPIDVLSKVGSYCLGEMAGFILEC
AQLNIPVVIDGFPTTAAALIAAQLNPEVLDCMFAGHCSKVKGHRVLLDALNLRPILDLDMRLGEGTGAVLSFSIIEAAIK
MINEMATFDDANVSKGKEK

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=335, Percent_Identity=39.4029850746269, Blast_Score=219, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36690; Mature: 36559

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKDLENKIKERLNSLTKPKGSLGFLEDIALKMGKIQGKVLPNLPEKKAVFVFAGDHGV
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC
TEEGVSAYPKEVTAQMVLNFLNGGAAINVFSRHVGSEVYVIDAGVDYDFPAHERLLNKKV
CHHHHHHCHHHHHHHHHHHHHCCCCEEHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH
GKGTKNFSKEPAMTREEAEKSIEYGKEIARFAKEKGFELVAVGDMGIGNTTTATTIAIAL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHH
GHNLSELIDIGTVITGQQLEKKEAVVRQAISIHEPFMDPIDVLSKVGSYCLGEMAGFILE
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
CAQLNIPVVIDGFPTTAAALIAAQLNPEVLDCMFAGHCSKVKGHRVLLDALNLRPILDLD
HHHCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEHHHCCCCEEEHH
MRLGEGTGAVLSFSIIEAAIKMINEMATFDDANVSKGKEK
HCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AKKDLENKIKERLNSLTKPKGSLGFLEDIALKMGKIQGKVLPNLPEKKAVFVFAGDHGV
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC
TEEGVSAYPKEVTAQMVLNFLNGGAAINVFSRHVGSEVYVIDAGVDYDFPAHERLLNKKV
CHHHHHHCHHHHHHHHHHHHHCCCCEEHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH
GKGTKNFSKEPAMTREEAEKSIEYGKEIARFAKEKGFELVAVGDMGIGNTTTATTIAIAL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHH
GHNLSELIDIGTVITGQQLEKKEAVVRQAISIHEPFMDPIDVLSKVGSYCLGEMAGFILE
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
CAQLNIPVVIDGFPTTAAALIAAQLNPEVLDCMFAGHCSKVKGHRVLLDALNLRPILDLD
HHHCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEHHHCCCCEEEHH
MRLGEGTGAVLSFSIIEAAIKMINEMATFDDANVSKGKEK
HCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA