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The map label for this gene is phoP [H]

Identifier: 239616845

GI number: 239616845

Start: 469863

End: 471008

Strand: Direct

Name: phoP [H]

Synonym: Kole_0440

Alternate gene names: 239616845

Gene position: 469863-471008 (Clockwise)

Preceding gene: 239616844

Following gene: 239616846

Centisome position: 20.41

GC content: 39.27

Gene sequence:

>1146_bases
ATGAAGAGGGTGCTCGTTATTGACGACGATCGAACAGTAAGAATGTTGCTCAAAGTGATTCTCAAAAAAGCAGGATATGA
TGTTGTTGAGTGTGCAAATGGAAAAACCTCTTTAAAAAAGGCTGAAAGTTTCAAACCCGATTTGATTCTTCTTGACCTGA
TGTTACCGGATATAAATGGACTTCAGCTCCTTGAAACCTTCACATCCAAAGAGAATCTAAAAGATGTTCCCATAATAGTA
CTAACGGGTTCAACAGATGAAGAGAACAAACTAACCGCATTGAGAAGCGGTGCGGTGGATTTTATTACCAAACCTTTTCT
TTCGGAAGAGGTTTTGCTACGTGTTCGTACACAACTTAGAATCCATAGCCTTATACACTCTTTACAGGAGGCGGTTGAAA
AACTACAGGACGACGTCGCTGCAGCTGCGAAGATTCAGAAAGCATTGGTCCCGGTTTCCACTCCACAGGGGTTTAGAGAC
AGGGTTAATTGGATATACGAACCTTCGTACAATGTGGGAGGAGACATCTTTGATTTCATCAAACTTAATGACGAAAAAGA
ACTTATATATCTTGCAGATGTTGCTGGACATGGGGTCAAAGCGGCAATGCTCTCGGTAATCTTTCACAGATTTGTTGAGG
ATTATGTAGAAAACATAAAAAATCAGGGTGAAAAACTGGAACTTTCTAAGCTCATAAGAGCTCTGGAAGATAATTTCAAA
TTTGACAAGTTCGATCTGTTTATCACAACCGTAGCCGTGGTTATTGATAGGAAAAACATGAGGATCGAAATCGGAAATGC
TGGTCATCCATCTCCATTCTTTATGAAAAAAAAGGACAGGAAGACTTTTTTTGTAAACGATCCGGTTGAAAGCATGCTGG
GCCTGGGACTCGTCGAAGGTAAAACGAAGGTTTTAGAAATAAACAGAGGCGACAGAATATACCTCTTTACCGATGGTGTC
ATAGAAGTTGTAAATTCCTCAGGAACACAATTCGGCTTAGAAAATCTTAAAAAAAACCTGGAAAAAAACATTTGGTCCAA
ACTTGAAGAAAGCGTTAAAGATCTCTTTAATGAAGTTAAAACCTATAAAAATGGCGAGCATTTCGAGGACGATGTTACTA
TAATAGGTATAGAATTCACCGGCTGA

Upstream 100 bases:

>100_bases
CATTATTCCTAGCTATCTTGCTTCTAAACTCACTCCAGCAGAAGCGTTACGCTATTTTGAATGAACTCACAACTGTTTCG
ACGCATTTAGGAGGGGGAAA

Downstream 100 bases:

>100_bases
ATGTTTTCATTAAAAAAAAACAGGGGGGATATCGTGTTTTCTTTTAAGGTTGTAGATGAGAAATTCGCCATCATAAGCGT
TGAAGAAAGGTCACGTATCA

Product: response regulator receiver modulated serine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKRVLVIDDDRTVRMLLKVILKKAGYDVVECANGKTSLKKAESFKPDLILLDLMLPDINGLQLLETFTSKENLKDVPIIV
LTGSTDEENKLTALRSGAVDFITKPFLSEEVLLRVRTQLRIHSLIHSLQEAVEKLQDDVAAAAKIQKALVPVSTPQGFRD
RVNWIYEPSYNVGGDIFDFIKLNDEKELIYLADVAGHGVKAAMLSVIFHRFVEDYVENIKNQGEKLELSKLIRALEDNFK
FDKFDLFITTVAVVIDRKNMRIEIGNAGHPSPFFMKKKDRKTFFVNDPVESMLGLGLVEGKTKVLEINRGDRIYLFTDGV
IEVVNSSGTQFGLENLKKNLEKNIWSKLEESVKDLFNEVKTYKNGEHFEDDVTIIGIEFTG

Sequences:

>Translated_381_residues
MKRVLVIDDDRTVRMLLKVILKKAGYDVVECANGKTSLKKAESFKPDLILLDLMLPDINGLQLLETFTSKENLKDVPIIV
LTGSTDEENKLTALRSGAVDFITKPFLSEEVLLRVRTQLRIHSLIHSLQEAVEKLQDDVAAAAKIQKALVPVSTPQGFRD
RVNWIYEPSYNVGGDIFDFIKLNDEKELIYLADVAGHGVKAAMLSVIFHRFVEDYVENIKNQGEKLELSKLIRALEDNFK
FDKFDLFITTVAVVIDRKNMRIEIGNAGHPSPFFMKKKDRKTFFVNDPVESMLGLGLVEGKTKVLEINRGDRIYLFTDGV
IEVVNSSGTQFGLENLKKNLEKNIWSKLEESVKDLFNEVKTYKNGEHFEDDVTIIGIEFTG
>Mature_381_residues
MKRVLVIDDDRTVRMLLKVILKKAGYDVVECANGKTSLKKAESFKPDLILLDLMLPDINGLQLLETFTSKENLKDVPIIV
LTGSTDEENKLTALRSGAVDFITKPFLSEEVLLRVRTQLRIHSLIHSLQEAVEKLQDDVAAAAKIQKALVPVSTPQGFRD
RVNWIYEPSYNVGGDIFDFIKLNDEKELIYLADVAGHGVKAAMLSVIFHRFVEDYVENIKNQGEKLELSKLIRALEDNFK
FDKFDLFITTVAVVIDRKNMRIEIGNAGHPSPFFMKKKDRKTFFVNDPVESMLGLGLVEGKTKVLEINRGDRIYLFTDGV
IEVVNSSGTQFGLENLKKNLEKNIWSKLEESVKDLFNEVKTYKNGEHFEDDVTIIGIEFTG

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=132, Percent_Identity=31.8181818181818, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786911, Length=123, Percent_Identity=37.3983739837398, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788550, Length=135, Percent_Identity=31.1111111111111, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082012, Length=131, Percent_Identity=35.1145038167939, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787375, Length=121, Percent_Identity=37.1900826446281, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788394, Length=128, Percent_Identity=35.9375, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789809, Length=120, Percent_Identity=39.1666666666667, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787487, Length=205, Percent_Identity=28.2926829268293, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=36.4406779661017, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790863, Length=116, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790860, Length=122, Percent_Identity=34.4262295081967, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788191, Length=107, Percent_Identity=29.9065420560748, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790552, Length=190, Percent_Identity=26.3157894736842, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787229, Length=116, Percent_Identity=31.8965517241379, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 43172; Mature: 43172

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLVIDDDRTVRMLLKVILKKAGYDVVECANGKTSLKKAESFKPDLILLDLMLPDING
CCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCEEEEEECCCCCCC
LQLLETFTSKENLKDVPIIVLTGSTDEENKLTALRSGAVDFITKPFLSEEVLLRVRTQLR
HHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHH
IHSLIHSLQEAVEKLQDDVAAAAKIQKALVPVSTPQGFRDRVNWIYEPSYNVGGDIFDFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCEEECCCCCCCCCCEEHE
KLNDEKELIYLADVAGHGVKAAMLSVIFHRFVEDYVENIKNQGEKLELSKLIRALEDNFK
EECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCC
FDKFDLFITTVAVVIDRKNMRIEIGNAGHPSPFFMKKKDRKTFFVNDPVESMLGLGLVEG
CCHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCEECCCCCEEEECCCHHHHHCCCEECC
KTKVLEINRGDRIYLFTDGVIEVVNSSGTQFGLENLKKNLEKNIWSKLEESVKDLFNEVK
CEEEEEECCCCEEEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYKNGEHFEDDVTIIGIEFTG
HCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MKRVLVIDDDRTVRMLLKVILKKAGYDVVECANGKTSLKKAESFKPDLILLDLMLPDING
CCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCEEEEEECCCCCCC
LQLLETFTSKENLKDVPIIVLTGSTDEENKLTALRSGAVDFITKPFLSEEVLLRVRTQLR
HHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHH
IHSLIHSLQEAVEKLQDDVAAAAKIQKALVPVSTPQGFRDRVNWIYEPSYNVGGDIFDFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCEEECCCCCCCCCCEEHE
KLNDEKELIYLADVAGHGVKAAMLSVIFHRFVEDYVENIKNQGEKLELSKLIRALEDNFK
EECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCC
FDKFDLFITTVAVVIDRKNMRIEIGNAGHPSPFFMKKKDRKTFFVNDPVESMLGLGLVEG
CCHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCEECCCCCEEEECCCHHHHHCCCEECC
KTKVLEINRGDRIYLFTDGVIEVVNSSGTQFGLENLKKNLEKNIWSKLEESVKDLFNEVK
CEEEEEECCCCEEEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYKNGEHFEDDVTIIGIEFTG
HCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]