Click here to switch to the map view.

The map label for this gene is yfbK [C]

Identifier: 239616825

GI number: 239616825

Start: 445302

End: 447494

Strand: Reverse

Name: yfbK [C]

Synonym: Kole_0418

Alternate gene names: 239616825

Gene position: 447494-445302 (Counterclockwise)

Preceding gene: 239616826

Following gene: 239616824

Centisome position: 19.44

GC content: 41.45

Gene sequence:

>2193_bases
ATGAAAAAAATGGTTGGTGCGTTGCTTGTTTTATTTCTGGTGATTTCTTCTATCGCCATTGCGGATGGGATAGTTATCCC
GAATTGGGAATCGCATGTTATGCCACCACTCCCTGATGTACAAATGTTTTACATGACTTATCACTATGTGACTATAACTG
TAGAGAATGGTATCGCAAAGGTAAGAATCGAAGAGGAGTTTGTGAATCCGAATTCTATGCCTATCGAAGCTGAGTACATC
TTCCCTGTTCCATTAGGTGCCGTTATAGACAGGTTTTCCATGATCGTGGGCGATCAGGTTTATGAAGGAAAGGTTTTGCC
AGCTGAAGAGGCACGGAAAATCTACCAGGATATCGTTAGAAGAATGAAAGATCCTGCGCTTTTAGAATATGCCAACAGCA
GAATGGTGAGGATGAAGGTTTACCCATTTGAACCGGGAGAGCACAGGCGATTTGTTATTGAGTATGTTCAACCTTTGGAG
CTGTGGGGATCATCGTATACGATGACGTATCCGTTGAAAATCGAAAGTATGCTTTCCAGATCCATAGAAAACGTTCGGAT
TGAAGTGGTCGCTGATCCGAACGAAATCTCTGACGTCTTTTCCCCGATACATTCTTTTAATTACATAAAAAAAGGCGACG
AGAGTTCCTGGGTATTCTCAGCATCCGATTATGTTCCACGTTCTGATGTATCTTTAGCTTTGACAGTAACAGGGGGGACG
CTTTCTTCCTCGATCATGAATTATTGGGATGAAGCAGACAGGCGCGGGTACTTTCTTCTCACCCTTGTGCCACCAAGAGA
GCCTGAAAGAATCATTCCGAAAGATATAGTTTTTATTCTGGACATTTCCGGGTCTATGAGCGGTCAAAAGATTGAAAAAG
CGAAACTCGCGTTGCTGCAGGTTCTGCAAATGCTCCATGAAGGTGATAGGTTTTCAATCATAACTTTCAACAATGAAGTA
AACAATCTTACAGAGCGTCTGCTGCCTTTTTCGGATAGAACAGAATGGTATCCGGCAGTAAAGCAAATAATGGCTGGTGG
CATGACAAATATTCATGATGCATTGCTTGAAGGTATTGAAGTTCTTGGTACGCAGAGTACGGATGACAGGTATAAAGTTG
TGCTGTTTCTCACCGATGGTGCACCAACAGAAGGTATTACTGATATTGGAACAATTATCAGGGATTCCACAAAACTTGCT
AAGGTAAGAGATGTACATCTTTTTGTTTTTGGTGTAGGATACGATGTAAATGCCGAATTACTTGATGAACTAGCAGAAAA
AGGAGGGGGAAAGGTTAAATACATCGTTGAGAACGAAGAAATTGATGAAAAGGTTCTGGAGCTTTATAGAATGATAGAGA
CTCCGGTCATGTCGAATGTTCATCTTGAAATAAACGGTACAGATATTTCTTATGTTCTTCCCAAGGGACCTTACACCCTG
TTCTCTGGAACGGCATTGAGGATATCAGGCGTGTATTACCATGAAGGTGTGGTAAACGTAACCCTTTCATGGGAGGAGAA
ACTCAATGGCGTCATTGTCCAGAATAAGATCAAATACAAATTTGATTTAACAAGGAACTCCAGTTTCCCGTTCATTGCTA
CTTTATGGGCACAAAAGCGCATTAGTGAACTGGCGAATATCTACAGGTATGATGAAACCCTGACCCCAGCACAGCGCGAA
GAGATAAGGCAAGAAATAATCAATTTATCAAAGAAATACAACATAATCAATGAATTCACTTCTTATCTCATAGATCCCGA
GAGCGAAATGGCTGCTGATTACAATGTCCCGATTCGTACCGGAAATAAATCGGTTATGCCAACACTGGTAGCACCATTGG
GTGGAGTCATTAATTATGTTGAAGTTGGCGATATTCTCGCTTCGAAAGCTGTATCTGAAATGAAAGAGGATATCATTATT
GCAGGGGAAGAAAATCGTCAGTATGTCGGTGATAAACTATTTGCAAAGTACGATGGCATTTGGACTCAGGAAGGGTTTGA
AGAGTACAAAGGGCTGGAAGTTCACATCAAATCCTTCAGCGATGCGTATTTCCATCTGTTTTCCAGGGATTTTTGGATTG
CTGATGTACTAAAGCTTGGAGATAAAGTTCGGTTCATCTATGAGGGATACAAAATCATTACTGGAAATGATGGAATGGAG
ACCGTTGATGAGCTTCCTGAGGTTCTGAGATGA

Upstream 100 bases:

>100_bases
CTTTTTTAGTTTTGAACGAACATTCTTTTTAGGTGGTCAAAGAATTGTTAGCATAAGTCTTTGCCGGCGGGGGAAACTAA
CGAGCGAAGGGGTGTCGTGT

Downstream 100 bases:

>100_bases
ACAGTAATTTTAATGAAAAACTTAATACAAGCCAAATTAACTGAAAAGCCCGACAGATGTCGGGCTTTTTTATAATATAA
TCAAGAAAAGTTACAAAATA

Product: von Willebrand factor type A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MKKMVGALLVLFLVISSIAIADGIVIPNWESHVMPPLPDVQMFYMTYHYVTITVENGIAKVRIEEEFVNPNSMPIEAEYI
FPVPLGAVIDRFSMIVGDQVYEGKVLPAEEARKIYQDIVRRMKDPALLEYANSRMVRMKVYPFEPGEHRRFVIEYVQPLE
LWGSSYTMTYPLKIESMLSRSIENVRIEVVADPNEISDVFSPIHSFNYIKKGDESSWVFSASDYVPRSDVSLALTVTGGT
LSSSIMNYWDEADRRGYFLLTLVPPREPERIIPKDIVFILDISGSMSGQKIEKAKLALLQVLQMLHEGDRFSIITFNNEV
NNLTERLLPFSDRTEWYPAVKQIMAGGMTNIHDALLEGIEVLGTQSTDDRYKVVLFLTDGAPTEGITDIGTIIRDSTKLA
KVRDVHLFVFGVGYDVNAELLDELAEKGGGKVKYIVENEEIDEKVLELYRMIETPVMSNVHLEINGTDISYVLPKGPYTL
FSGTALRISGVYYHEGVVNVTLSWEEKLNGVIVQNKIKYKFDLTRNSSFPFIATLWAQKRISELANIYRYDETLTPAQRE
EIRQEIINLSKKYNIINEFTSYLIDPESEMAADYNVPIRTGNKSVMPTLVAPLGGVINYVEVGDILASKAVSEMKEDIII
AGEENRQYVGDKLFAKYDGIWTQEGFEEYKGLEVHIKSFSDAYFHLFSRDFWIADVLKLGDKVRFIYEGYKIITGNDGME
TVDELPEVLR

Sequences:

>Translated_730_residues
MKKMVGALLVLFLVISSIAIADGIVIPNWESHVMPPLPDVQMFYMTYHYVTITVENGIAKVRIEEEFVNPNSMPIEAEYI
FPVPLGAVIDRFSMIVGDQVYEGKVLPAEEARKIYQDIVRRMKDPALLEYANSRMVRMKVYPFEPGEHRRFVIEYVQPLE
LWGSSYTMTYPLKIESMLSRSIENVRIEVVADPNEISDVFSPIHSFNYIKKGDESSWVFSASDYVPRSDVSLALTVTGGT
LSSSIMNYWDEADRRGYFLLTLVPPREPERIIPKDIVFILDISGSMSGQKIEKAKLALLQVLQMLHEGDRFSIITFNNEV
NNLTERLLPFSDRTEWYPAVKQIMAGGMTNIHDALLEGIEVLGTQSTDDRYKVVLFLTDGAPTEGITDIGTIIRDSTKLA
KVRDVHLFVFGVGYDVNAELLDELAEKGGGKVKYIVENEEIDEKVLELYRMIETPVMSNVHLEINGTDISYVLPKGPYTL
FSGTALRISGVYYHEGVVNVTLSWEEKLNGVIVQNKIKYKFDLTRNSSFPFIATLWAQKRISELANIYRYDETLTPAQRE
EIRQEIINLSKKYNIINEFTSYLIDPESEMAADYNVPIRTGNKSVMPTLVAPLGGVINYVEVGDILASKAVSEMKEDIII
AGEENRQYVGDKLFAKYDGIWTQEGFEEYKGLEVHIKSFSDAYFHLFSRDFWIADVLKLGDKVRFIYEGYKIITGNDGME
TVDELPEVLR
>Mature_730_residues
MKKMVGALLVLFLVISSIAIADGIVIPNWESHVMPPLPDVQMFYMTYHYVTITVENGIAKVRIEEEFVNPNSMPIEAEYI
FPVPLGAVIDRFSMIVGDQVYEGKVLPAEEARKIYQDIVRRMKDPALLEYANSRMVRMKVYPFEPGEHRRFVIEYVQPLE
LWGSSYTMTYPLKIESMLSRSIENVRIEVVADPNEISDVFSPIHSFNYIKKGDESSWVFSASDYVPRSDVSLALTVTGGT
LSSSIMNYWDEADRRGYFLLTLVPPREPERIIPKDIVFILDISGSMSGQKIEKAKLALLQVLQMLHEGDRFSIITFNNEV
NNLTERLLPFSDRTEWYPAVKQIMAGGMTNIHDALLEGIEVLGTQSTDDRYKVVLFLTDGAPTEGITDIGTIIRDSTKLA
KVRDVHLFVFGVGYDVNAELLDELAEKGGGKVKYIVENEEIDEKVLELYRMIETPVMSNVHLEINGTDISYVLPKGPYTL
FSGTALRISGVYYHEGVVNVTLSWEEKLNGVIVQNKIKYKFDLTRNSSFPFIATLWAQKRISELANIYRYDETLTPAQRE
EIRQEIINLSKKYNIINEFTSYLIDPESEMAADYNVPIRTGNKSVMPTLVAPLGGVINYVEVGDILASKAVSEMKEDIII
AGEENRQYVGDKLFAKYDGIWTQEGFEEYKGLEVHIKSFSDAYFHLFSRDFWIADVLKLGDKVRFIYEGYKIITGNDGME
TVDELPEVLR

Specific function: Unknown

COG id: COG2304

COG function: function code R; Uncharacterized protein containing a von Willebrand factor type A (vWA) domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

Organism=Homo sapiens, GI262050538, Length=613, Percent_Identity=23.8172920065253, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI31542984, Length=599, Percent_Identity=23.873121869783, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI70778918, Length=590, Percent_Identity=23.5593220338983, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI153945780, Length=585, Percent_Identity=24.2735042735043, Blast_Score=117, Evalue=5e-26,
Organism=Homo sapiens, GI49355778, Length=585, Percent_Identity=24.2735042735043, Blast_Score=117, Evalue=5e-26,
Organism=Homo sapiens, GI133925809, Length=562, Percent_Identity=22.9537366548043, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI38348336, Length=633, Percent_Identity=23.3807266982622, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI153945711, Length=352, Percent_Identity=27.5568181818182, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI156119625, Length=450, Percent_Identity=23.1111111111111, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI261878614, Length=199, Percent_Identity=29.1457286432161, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI261878618, Length=199, Percent_Identity=29.1457286432161, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI261878616, Length=199, Percent_Identity=29.1457286432161, Blast_Score=97, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002035 [H]

Pfam domain/function: PF00092 VWA [H]

EC number: NA

Molecular weight: Translated: 83011; Mature: 83011

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMVGALLVLFLVISSIAIADGIVIPNWESHVMPPLPDVQMFYMTYHYVTITVENGIAK
CHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEEEEEEEEEEEEECCEEE
VRIEEEFVNPNSMPIEAEYIFPVPLGAVIDRFSMIVGDQVYEGKVLPAEEARKIYQDIVR
EEEEHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHH
RMKDPALLEYANSRMVRMKVYPFEPGEHRRFVIEYVQPLELWGSSYTMTYPLKIESMLSR
HCCCCHHHHHCCCCEEEEEEECCCCCCCCEEHHHHHHHHHHCCCCEEEEEEEEHHHHHHC
SIENVRIEVVADPNEISDVFSPIHSFNYIKKGDESSWVFSASDYVPRSDVSLALTVTGGT
CCCCEEEEEEECCHHHHHHHHHHHHCCHHCCCCCCCEEEECCCCCCCCCCEEEEEEECCH
LSSSIMNYWDEADRRGYFLLTLVPPREPERIIPKDIVFILDISGSMSGQKIEKAKLALLQ
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
VLQMLHEGDRFSIITFNNEVNNLTERLLPFSDRTEWYPAVKQIMAGGMTNIHDALLEGIE
HHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
VLGTQSTDDRYKVVLFLTDGAPTEGITDIGTIIRDSTKLAKVRDVHLFVFGVGYDVNAEL
HHCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHCCCHHHEEEEEEEEEEEECCCCCHHH
LDELAEKGGGKVKYIVENEEIDEKVLELYRMIETPVMSNVHLEINGTDISYVLPKGPYTL
HHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEECCCCEEE
FSGTALRISGVYYHEGVVNVTLSWEEKLNGVIVQNKIKYKFDLTRNSSFPFIATLWAQKR
ECCCEEEEEEEEEECCEEEEEEEHHHHCCCEEEEEEEEEEEEECCCCCCCCHHHHHHHHH
ISELANIYRYDETLTPAQREEIRQEIINLSKKYNIINEFTSYLIDPESEMAADYNVPIRT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEC
GNKSVMPTLVAPLGGVINYVEVGDILASKAVSEMKEDIIIAGEENRQYVGDKLFAKYDGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHCCC
WTQEGFEEYKGLEVHIKSFSDAYFHLFSRDFWIADVLKLGDKVRFIYEGYKIITGNDGME
CCCCCHHHHCCEEEEEECCCHHHHHHHCCCHHHHHHHHCCCCEEEEEECEEEEECCCCHH
TVDELPEVLR
HHHHHHHHHC
>Mature Secondary Structure
MKKMVGALLVLFLVISSIAIADGIVIPNWESHVMPPLPDVQMFYMTYHYVTITVENGIAK
CHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEEEEEEEEEEEEECCEEE
VRIEEEFVNPNSMPIEAEYIFPVPLGAVIDRFSMIVGDQVYEGKVLPAEEARKIYQDIVR
EEEEHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHH
RMKDPALLEYANSRMVRMKVYPFEPGEHRRFVIEYVQPLELWGSSYTMTYPLKIESMLSR
HCCCCHHHHHCCCCEEEEEEECCCCCCCCEEHHHHHHHHHHCCCCEEEEEEEEHHHHHHC
SIENVRIEVVADPNEISDVFSPIHSFNYIKKGDESSWVFSASDYVPRSDVSLALTVTGGT
CCCCEEEEEEECCHHHHHHHHHHHHCCHHCCCCCCCEEEECCCCCCCCCCEEEEEEECCH
LSSSIMNYWDEADRRGYFLLTLVPPREPERIIPKDIVFILDISGSMSGQKIEKAKLALLQ
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
VLQMLHEGDRFSIITFNNEVNNLTERLLPFSDRTEWYPAVKQIMAGGMTNIHDALLEGIE
HHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
VLGTQSTDDRYKVVLFLTDGAPTEGITDIGTIIRDSTKLAKVRDVHLFVFGVGYDVNAEL
HHCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHCCCHHHEEEEEEEEEEEECCCCCHHH
LDELAEKGGGKVKYIVENEEIDEKVLELYRMIETPVMSNVHLEINGTDISYVLPKGPYTL
HHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEECCCCEEE
FSGTALRISGVYYHEGVVNVTLSWEEKLNGVIVQNKIKYKFDLTRNSSFPFIATLWAQKR
ECCCEEEEEEEEEECCEEEEEEEHHHHCCCEEEEEEEEEEEEECCCCCCCCHHHHHHHHH
ISELANIYRYDETLTPAQREEIRQEIINLSKKYNIINEFTSYLIDPESEMAADYNVPIRT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEC
GNKSVMPTLVAPLGGVINYVEVGDILASKAVSEMKEDIIIAGEENRQYVGDKLFAKYDGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHCCC
WTQEGFEEYKGLEVHIKSFSDAYFHLFSRDFWIADVLKLGDKVRFIYEGYKIITGNDGME
CCCCCHHHHCCEEEEEECCCHHHHHHHCCCHHHHHHHHCCCCEEEEEECEEEEECCCCHH
TVDELPEVLR
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]