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The map label for this gene is nagC [H]

Identifier: 239616707

GI number: 239616707

Start: 326386

End: 327540

Strand: Reverse

Name: nagC [H]

Synonym: Kole_0300

Alternate gene names: 239616707

Gene position: 327540-326386 (Counterclockwise)

Preceding gene: 239616708

Following gene: 239616705

Centisome position: 14.23

GC content: 38.96

Gene sequence:

>1155_bases
GTGAAAATCGAAGAGATTCGTTGGGACAATCTTACAAAATTGCTGGACTTTCTTTACGCTGGCAAGCGTGTTTTAAGAAA
AGAATTAACAGAAAAAATGAAAATAAGAAATTCAACTCTGAGTTATCTGTTGAACGAACTAACGAAGTTAGAGATGATCA
GAATAGAAAAAATTGCCGGTGGCAGGGGAAGGCCGAATCATGTGGTTTCATTAAATCCTGAACACGGAACGGTTTTTGGT
GTTAAATTGGGGCGCGAATCTCTTCGGGCAATAGTTTTTGATTTCTCCTTGAAAAAAATTGACTCGATAGAATATCCGTT
ACATGAAATTGGCAAATCAATACCGGATGTAATAAGCGAACTAAAAAGATTTGTTGAGCATTATAAACCTGTCGGAGCCG
GGTTTGCGGTTTCGGGAACAGTTGATTTAAAAAGCAAAAGGATAATAAAATCGCCCATATTGAACCTTAGAAATTTTGAT
TTTGAACCCGTTATTTCTAAGTTGGCCCTTTCGGAATTCGTTATGTGCAACGATGTTGATGCTTTGCATATTGGTCAAAT
CGTGGAATCCGGAATAATAAACAAATCTTCGCTGACCGTGAGTTTTGGTGTGGGGATAGGCGCGTCTTATTATGATGGTC
AGGATATATTCGTTGGGAGTGATGGAAAAACGGCCTTTGAGTTTGGCCACCATGGAGTCGACCCTGATGGTGAGAAGTGT
TATTGTGGACGTATTGGATGTCTTGAAACTGTGGCCTCAGAGTATGTTCTTGTGAAAGAAAGAGCGGGTAGTATCGGCAA
TTTTGTTGCCAACTTTGACCTTTTTAGACCGATTATAAATCAATTTAGAGAGAAGGCAAAAAAAGAAGAAAGACTGCAGG
AATATGAACGCATAATAAAAAGTTTGTCTTATTATCTGTCGAATTTAGTTCTGTCGCTAAGGCCGGCAATCTTGTGGATC
GGCGGTGAAGGGATTGTTTCAGAATGGATCTTTAACGATATCGTCAAATCTATCCATCTCAATATAGAAGATGGTTGGGA
AATAAAGCCTGAAATCATGCGTATAACTGATCCAGAATCCTGGGAAAAGGGAGCTGCGTTTTTGCTGTTGAGAAAATATA
TAAGTTCCAGGATAAAAGTTGGGAATAAGGGATAA

Upstream 100 bases:

>100_bases
TTATTCCGATCTTGATTTATCTTCTTTTGCAGAGATATTATGTTAAAGGGATGGTCGGTTGGACCATAAAATGAGTAAGA
CTTGAACTGGGGGAATCAGT

Downstream 100 bases:

>100_bases
AAACTCGAGATCCGAGAAAACGAGAATCCGAGACCCGAGAACCGAGAGTCCGAGAATATAAAATCGTTGCGGGTTGTACG
TTGTAGGTTGTACGTAAAAA

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKIEEIRWDNLTKLLDFLYAGKRVLRKELTEKMKIRNSTLSYLLNELTKLEMIRIEKIAGGRGRPNHVVSLNPEHGTVFG
VKLGRESLRAIVFDFSLKKIDSIEYPLHEIGKSIPDVISELKRFVEHYKPVGAGFAVSGTVDLKSKRIIKSPILNLRNFD
FEPVISKLALSEFVMCNDVDALHIGQIVESGIINKSSLTVSFGVGIGASYYDGQDIFVGSDGKTAFEFGHHGVDPDGEKC
YCGRIGCLETVASEYVLVKERAGSIGNFVANFDLFRPIINQFREKAKKEERLQEYERIIKSLSYYLSNLVLSLRPAILWI
GGEGIVSEWIFNDIVKSIHLNIEDGWEIKPEIMRITDPESWEKGAAFLLLRKYISSRIKVGNKG

Sequences:

>Translated_384_residues
MKIEEIRWDNLTKLLDFLYAGKRVLRKELTEKMKIRNSTLSYLLNELTKLEMIRIEKIAGGRGRPNHVVSLNPEHGTVFG
VKLGRESLRAIVFDFSLKKIDSIEYPLHEIGKSIPDVISELKRFVEHYKPVGAGFAVSGTVDLKSKRIIKSPILNLRNFD
FEPVISKLALSEFVMCNDVDALHIGQIVESGIINKSSLTVSFGVGIGASYYDGQDIFVGSDGKTAFEFGHHGVDPDGEKC
YCGRIGCLETVASEYVLVKERAGSIGNFVANFDLFRPIINQFREKAKKEERLQEYERIIKSLSYYLSNLVLSLRPAILWI
GGEGIVSEWIFNDIVKSIHLNIEDGWEIKPEIMRITDPESWEKGAAFLLLRKYISSRIKVGNKG
>Mature_384_residues
MKIEEIRWDNLTKLLDFLYAGKRVLRKELTEKMKIRNSTLSYLLNELTKLEMIRIEKIAGGRGRPNHVVSLNPEHGTVFG
VKLGRESLRAIVFDFSLKKIDSIEYPLHEIGKSIPDVISELKRFVEHYKPVGAGFAVSGTVDLKSKRIIKSPILNLRNFD
FEPVISKLALSEFVMCNDVDALHIGQIVESGIINKSSLTVSFGVGIGASYYDGQDIFVGSDGKTAFEFGHHGVDPDGEKC
YCGRIGCLETVASEYVLVKERAGSIGNFVANFDLFRPIINQFREKAKKEERLQEYERIIKSLSYYLSNLVLSLRPAILWI
GGEGIVSEWIFNDIVKSIHLNIEDGWEIKPEIMRITDPESWEKGAAFLLLRKYISSRIKVGNKG

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1786891, Length=242, Percent_Identity=24.3801652892562, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082127, Length=273, Percent_Identity=25.2747252747253, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 43390; Mature: 43390

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEEIRWDNLTKLLDFLYAGKRVLRKELTEKMKIRNSTLSYLLNELTKLEMIRIEKIAG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRGRPNHVVSLNPEHGTVFGVKLGRESLRAIVFDFSLKKIDSIEYPLHEIGKSIPDVISE
CCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LKRFVEHYKPVGAGFAVSGTVDLKSKRIIKSPILNLRNFDFEPVISKLALSEFVMCNDVD
HHHHHHHCCCCCCCEEEECEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
ALHIGQIVESGIINKSSLTVSFGVGIGASYYDGQDIFVGSDGKTAFEFGHHGVDPDGEKC
HHHHHHHHHHCCCCCCCEEEEECCCCCCCEECCCEEEEECCCCCHHHCCCCCCCCCCCEE
YCGRIGCLETVASEYVLVKERAGSIGNFVANFDLFRPIINQFREKAKKEERLQEYERIIK
EECCCHHHHHHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSYYLSNLVLSLRPAILWIGGEGIVSEWIFNDIVKSIHLNIEDGWEIKPEIMRITDPES
HHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCC
WEKGAAFLLLRKYISSRIKVGNKG
HHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKIEEIRWDNLTKLLDFLYAGKRVLRKELTEKMKIRNSTLSYLLNELTKLEMIRIEKIAG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRGRPNHVVSLNPEHGTVFGVKLGRESLRAIVFDFSLKKIDSIEYPLHEIGKSIPDVISE
CCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LKRFVEHYKPVGAGFAVSGTVDLKSKRIIKSPILNLRNFDFEPVISKLALSEFVMCNDVD
HHHHHHHCCCCCCCEEEECEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
ALHIGQIVESGIINKSSLTVSFGVGIGASYYDGQDIFVGSDGKTAFEFGHHGVDPDGEKC
HHHHHHHHHHCCCCCCCEEEEECCCCCCCEECCCEEEEECCCCCHHHCCCCCCCCCCCEE
YCGRIGCLETVASEYVLVKERAGSIGNFVANFDLFRPIINQFREKAKKEERLQEYERIIK
EECCCHHHHHHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSYYLSNLVLSLRPAILWIGGEGIVSEWIFNDIVKSIHLNIEDGWEIKPEIMRITDPES
HHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCC
WEKGAAFLLLRKYISSRIKVGNKG
HHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]