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The map label for this gene is licC [H]

Identifier: 238926031

GI number: 238926031

Start: 3429991

End: 3431304

Strand: Reverse

Name: licC [H]

Synonym: EUBREC_3689

Alternate gene names: 238926031

Gene position: 3431304-3429991 (Counterclockwise)

Preceding gene: 238926032

Following gene: 238926030

Centisome position: 99.47

GC content: 40.03

Gene sequence:

>1314_bases
ATGAAAGAGAAATTTAACGAAAAAGTAATCCCTGTAATCCTTAAGTTTATTAATACAAAGGCAATACAGTCAATAAAAAA
TGGTATGGTGACTTCCATGTCTCCTCTGATCATCGGATCAATCTTCCTGATCCTGTCAAACTTTCCGGTAAAGGCAGTTG
TCGATGTATTAGAGTCTACAGGAATCAAACCAGTATTAGATCAGGTATGTGGCGCAACATTCTCCATCAGTGCGTTGATT
GCAGTTATCGGTATCAGCTATAGCTATGCGAAACTGGAAAATCAGGAACCACTCAACTGTGGAATTATTTCACTGGCAAC
ATTCTTGATTCTGATGCCTTCGTCCATAACAACAGAAGGTGGAGAAGTTGTTAGTGGAATTATTAATAAGACATGGACAG
CAGGACAGGGAATGATTGGAGCAATCATTGTCGGATTGATTGTACCGCCTATTTACTGTTGGTTCTTGAAGAAAAATATA
CGTATTAAAATGCCGGCCGGAGTTCCGGAAGGTGTAACAAATGCATTCTCAGCATTAATCCCGGCATTCGTAATCCTGAC
AGGGGCTGCAGTAATTCACGGTATCTGTTCTATTGGATTCGACACAACAGGTATTGAAATTATTTACAAAGTTGTTCAGA
CACCACTTCAGAAAATGACAGACTCCCTTGGTGGAGCAGTTCTGATGTGCTTTACAGGACCATTCCTGTGGTTCTTCGGA
GTTCATGGTTCAACAGTAGTTGGTGGAATCATGACAGGACTATTACAGGCAAACAGCCTTGCAAATCAGGCTATTATTGA
CAGTGGTGTAGAACTTACAATAGCAAACGGAGGCCATATTGTAACACAGCAGTTTTATGATCAGTTTATCAATATAACAG
GTGCAGGTATCACAATCGGACTTGTAATGTATATGTTCTTCTTTGCAAAATCAAAACAGTTGAAAGCACTTGGTAAATTG
GGAATTATTCCGGCATTATTTGGAATCAATGAGCCAATTCTGTTTGGTGCTCCAGTCGTTATGAATCCAATGCTTGCAAT
TCCGTTTATTGGAATGCCTGTGATCGCATGTTTAATCCAGTATTTTGCACTGTATACAGGAATCTGCCCATTATATGGAG
CAACACAGATCCCATGGACTTGTCCACCGATTATCTCAGGATTCCTTTTAGCAGGATGGAAAAGTGCTTTACTTCAGTTA
GTGATCCTTTGTGTTTCATTCTTCGTTTATCTGCCATTCATTAAGAAGGTTGACAAGATGAATCTGGTTCAGGAGAAGAA
TCAGCCGGTAGAAGATGAGGATGAAGACTGGTAA

Upstream 100 bases:

>100_bases
ATGAATGTTTTGAAATTTGCATATAAGCTTGCGAAAAATAAATAAGAGAAAACAAAGATACACAATTTAAAGCAAAAAAC
AGAGCAAAGGGTAGTAGCAA

Downstream 100 bases:

>100_bases
AATCAGAATAAAAATAATAGCAGGATAGGAGAAAAAAATGAACGAAAAATTTGAATTGTCATGTTTTCAGATCATCACAT
ATGTAGGTACAGCAAGAACA

Product: PTS system, IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKEKFNEKVIPVILKFINTKAIQSIKNGMVTSMSPLIIGSIFLILSNFPVKAVVDVLESTGIKPVLDQVCGATFSISALI
AVIGISYSYAKLENQEPLNCGIISLATFLILMPSSITTEGGEVVSGIINKTWTAGQGMIGAIIVGLIVPPIYCWFLKKNI
RIKMPAGVPEGVTNAFSALIPAFVILTGAAVIHGICSIGFDTTGIEIIYKVVQTPLQKMTDSLGGAVLMCFTGPFLWFFG
VHGSTVVGGIMTGLLQANSLANQAIIDSGVELTIANGGHIVTQQFYDQFINITGAGITIGLVMYMFFFAKSKQLKALGKL
GIIPALFGINEPILFGAPVVMNPMLAIPFIGMPVIACLIQYFALYTGICPLYGATQIPWTCPPIISGFLLAGWKSALLQL
VILCVSFFVYLPFIKKVDKMNLVQEKNQPVEDEDEDW

Sequences:

>Translated_437_residues
MKEKFNEKVIPVILKFINTKAIQSIKNGMVTSMSPLIIGSIFLILSNFPVKAVVDVLESTGIKPVLDQVCGATFSISALI
AVIGISYSYAKLENQEPLNCGIISLATFLILMPSSITTEGGEVVSGIINKTWTAGQGMIGAIIVGLIVPPIYCWFLKKNI
RIKMPAGVPEGVTNAFSALIPAFVILTGAAVIHGICSIGFDTTGIEIIYKVVQTPLQKMTDSLGGAVLMCFTGPFLWFFG
VHGSTVVGGIMTGLLQANSLANQAIIDSGVELTIANGGHIVTQQFYDQFINITGAGITIGLVMYMFFFAKSKQLKALGKL
GIIPALFGINEPILFGAPVVMNPMLAIPFIGMPVIACLIQYFALYTGICPLYGATQIPWTCPPIISGFLLAGWKSALLQL
VILCVSFFVYLPFIKKVDKMNLVQEKNQPVEDEDEDW
>Mature_437_residues
MKEKFNEKVIPVILKFINTKAIQSIKNGMVTSMSPLIIGSIFLILSNFPVKAVVDVLESTGIKPVLDQVCGATFSISALI
AVIGISYSYAKLENQEPLNCGIISLATFLILMPSSITTEGGEVVSGIINKTWTAGQGMIGAIIVGLIVPPIYCWFLKKNI
RIKMPAGVPEGVTNAFSALIPAFVILTGAAVIHGICSIGFDTTGIEIIYKVVQTPLQKMTDSLGGAVLMCFTGPFLWFFG
VHGSTVVGGIMTGLLQANSLANQAIIDSGVELTIANGGHIVTQQFYDQFINITGAGITIGLVMYMFFFAKSKQLKALGKL
GIIPALFGINEPILFGAPVVMNPMLAIPFIGMPVIACLIQYFALYTGICPLYGATQIPWTCPPIISGFLLAGWKSALLQL
VILCVSFFVYLPFIKKVDKMNLVQEKNQPVEDEDEDW

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=451, Percent_Identity=30.5986696230599, Blast_Score=190, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 47017; Mature: 47017

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS51105 PTS_EIIC_TYPE_3 ; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKFNEKVIPVILKFINTKAIQSIKNGMVTSMSPLIIGSIFLILSNFPVKAVVDVLEST
CCCCHHCHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHC
GIKPVLDQVCGATFSISALIAVIGISYSYAKLENQEPLNCGIISLATFLILMPSSITTEG
CCCHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
GEVVSGIINKTWTAGQGMIGAIIVGLIVPPIYCWFLKKNIRIKMPAGVPEGVTNAFSALI
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHH
PAFVILTGAAVIHGICSIGFDTTGIEIIYKVVQTPLQKMTDSLGGAVLMCFTGPFLWFFG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHC
VHGSTVVGGIMTGLLQANSLANQAIIDSGVELTIANGGHIVTQQFYDQFINITGAGITIG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHH
LVMYMFFFAKSKQLKALGKLGIIPALFGINEPILFGAPVVMNPMLAIPFIGMPVIACLIQ
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHH
YFALYTGICPLYGATQIPWTCPPIISGFLLAGWKSALLQLVILCVSFFVYLPFIKKVDKM
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLVQEKNQPVEDEDEDW
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKEKFNEKVIPVILKFINTKAIQSIKNGMVTSMSPLIIGSIFLILSNFPVKAVVDVLEST
CCCCHHCHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHC
GIKPVLDQVCGATFSISALIAVIGISYSYAKLENQEPLNCGIISLATFLILMPSSITTEG
CCCHHHHHHCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
GEVVSGIINKTWTAGQGMIGAIIVGLIVPPIYCWFLKKNIRIKMPAGVPEGVTNAFSALI
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHH
PAFVILTGAAVIHGICSIGFDTTGIEIIYKVVQTPLQKMTDSLGGAVLMCFTGPFLWFFG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHC
VHGSTVVGGIMTGLLQANSLANQAIIDSGVELTIANGGHIVTQQFYDQFINITGAGITIG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHH
LVMYMFFFAKSKQLKALGKLGIIPALFGINEPILFGAPVVMNPMLAIPFIGMPVIACLIQ
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHH
YFALYTGICPLYGATQIPWTCPPIISGFLLAGWKSALLQLVILCVSFFVYLPFIKKVDKM
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLVQEKNQPVEDEDEDW
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]