Click here to switch to the map view.

The map label for this gene is malL [H]

Identifier: 238926020

GI number: 238926020

Start: 3419975

End: 3421600

Strand: Reverse

Name: malL [H]

Synonym: EUBREC_3678

Alternate gene names: 238926020

Gene position: 3421600-3419975 (Counterclockwise)

Preceding gene: 238926021

Following gene: 238926017

Centisome position: 99.19

GC content: 38.93

Gene sequence:

>1626_bases
ATGAAAAACAATTGGTGGAAAGAGTCCGTAGTGTATCAGATTTATCCGCAAAGTTTTATGGATAGCAACGGAGATGGAAT
CGGAGATTTTAACGGAATTATCCAGAAGCTTGATTATCTCCAAAATCTAGGCGTAGATGTATTATGGATATGCCCGATGT
ACGCTTCTCCACTTGTGGATAATGGATATGATATATCGGATTATTACAAGGTAAATCCAATCTTTGGAACAAACGAGGAT
ATGGAGCATTTAATAGAGGAGGCTCAAAAAAGAAAGATTAAAATCATATTGGATCTGGTGGTCAATCATTGCTCGGATCA
GCATGAATGGTTCCAGAAGGCAATGAAGGATCCTAATTGTGAGGAAGCGTCTTATTTTTACTTCCGAACAACGGAGAATG
ATAAAGAACCGAATAACTGGCGATCCAATTTTGGCGGATCCGTATGGTCGAGATTACCAGATGGCAGATGGTATTATCAT
ACGTTTGCGAAGGAACAGCCGGATCTGAACTGGGAATGCAAAGAGCTGCGTCAAAAAATTTATGAGATGATAAACTGGTG
GTTGGAAAAAGGAATCGCCGGTTTTCGTATCGATGCAATTACCTTTATCAAAAAAGACTTAAGTTTTGCCAGTCGTCCTA
CGAATGATGGGGAACGATATCCGGTTGAAAATCTTACGGATTATAAGGGAATCGGAACATTCCTTGATGAGATGAAAGAA
CAGTGCTTTGATAAATATAACTGTATGACAGTTGCCGAAGCACCGGGGGTTGACGATGCTGCTTTTGAACGGTATGCCGG
AAAGAATGGTTACTTTTCCATGATTTTCGATTTTGGATGGGAAAATATGGAAGGGGAAAATGATAAATCAAGCATTCATG
CGGTAGAACGGTGGAAGAAAAAAATGTTTACACATGTAGCGCATAATAGCGGAATCGGTTGGAGTGCTATCTTTTTAGAA
AATCATGATCAGTCCAGATGCCTGAACAAATTTCTGGAAAGAGAAAATATTAGTTTCTATAGTGCATCGGCACTGGCGAG
TATCTATTTCTTTTTATATGGAACGCCTTTTATATATCAGGGACAGGAAATTGGTATGACCAATGTTAAGTGGAAGAATA
TTAATGATATGGATGATATAAGGGCGAAAAGAACATATGAGGAAGCGGTCGGACAGGGCAAGGATCCGGATGAAGTACTT
GCATACTTTTCAGAGTTAGGAAGAGATAATGCAAGAACGCCGATGCAGTGGGATGACTCGGAAAATGGAGGATTTACGTG
TGGAAAGCCATGGATTAAATGCAATGATAATTATAGAACAATCAATGCACAGAGTCAGGTGAATGATCCGGATTCATTAT
ACAATTATTATAAGCGTTTGATTCAGTGTTACCATGACCATGCAGATATTGTGAGACAGGCGGAGTTTCGCCCGATGTAC
GAAGAATATCCGGGATTATTTGCATATGAAAGAGAAGTAAACGGCAAAGGTTTATTGGTAATCGTGAATTTTACAAATGA
AAAGCTGATGTTTCAAAAAATTGATCAAAAATGTGAATTATGCAATTATCATGAAACGGAGTCCGAATGGTTGCAACCAT
ATGAGGCGAGAATATACAGCAAATAA

Upstream 100 bases:

>100_bases
ATGTGCATGGCTCCTATTATTATCTTTTATTTGTTTAGTCAAAAATACATTGTAAAAGGTATTACAGAAGGGGCAATAAA
GTAAGGTGAGGAATTTGTGA

Downstream 100 bases:

>100_bases
AAAATTCTATGTGTAAAAGAAAACATTTTGGCGTTAAATGAAATTGGACTGTCAGTCGATTAAACTTTTTATAAATACAG
ACCTCTCAGATACTGAAAAG

Product: oligo-1,6-glucosidase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MKNNWWKESVVYQIYPQSFMDSNGDGIGDFNGIIQKLDYLQNLGVDVLWICPMYASPLVDNGYDISDYYKVNPIFGTNED
MEHLIEEAQKRKIKIILDLVVNHCSDQHEWFQKAMKDPNCEEASYFYFRTTENDKEPNNWRSNFGGSVWSRLPDGRWYYH
TFAKEQPDLNWECKELRQKIYEMINWWLEKGIAGFRIDAITFIKKDLSFASRPTNDGERYPVENLTDYKGIGTFLDEMKE
QCFDKYNCMTVAEAPGVDDAAFERYAGKNGYFSMIFDFGWENMEGENDKSSIHAVERWKKKMFTHVAHNSGIGWSAIFLE
NHDQSRCLNKFLERENISFYSASALASIYFFLYGTPFIYQGQEIGMTNVKWKNINDMDDIRAKRTYEEAVGQGKDPDEVL
AYFSELGRDNARTPMQWDDSENGGFTCGKPWIKCNDNYRTINAQSQVNDPDSLYNYYKRLIQCYHDHADIVRQAEFRPMY
EEYPGLFAYEREVNGKGLLVIVNFTNEKLMFQKIDQKCELCNYHETESEWLQPYEARIYSK

Sequences:

>Translated_541_residues
MKNNWWKESVVYQIYPQSFMDSNGDGIGDFNGIIQKLDYLQNLGVDVLWICPMYASPLVDNGYDISDYYKVNPIFGTNED
MEHLIEEAQKRKIKIILDLVVNHCSDQHEWFQKAMKDPNCEEASYFYFRTTENDKEPNNWRSNFGGSVWSRLPDGRWYYH
TFAKEQPDLNWECKELRQKIYEMINWWLEKGIAGFRIDAITFIKKDLSFASRPTNDGERYPVENLTDYKGIGTFLDEMKE
QCFDKYNCMTVAEAPGVDDAAFERYAGKNGYFSMIFDFGWENMEGENDKSSIHAVERWKKKMFTHVAHNSGIGWSAIFLE
NHDQSRCLNKFLERENISFYSASALASIYFFLYGTPFIYQGQEIGMTNVKWKNINDMDDIRAKRTYEEAVGQGKDPDEVL
AYFSELGRDNARTPMQWDDSENGGFTCGKPWIKCNDNYRTINAQSQVNDPDSLYNYYKRLIQCYHDHADIVRQAEFRPMY
EEYPGLFAYEREVNGKGLLVIVNFTNEKLMFQKIDQKCELCNYHETESEWLQPYEARIYSK
>Mature_541_residues
MKNNWWKESVVYQIYPQSFMDSNGDGIGDFNGIIQKLDYLQNLGVDVLWICPMYASPLVDNGYDISDYYKVNPIFGTNED
MEHLIEEAQKRKIKIILDLVVNHCSDQHEWFQKAMKDPNCEEASYFYFRTTENDKEPNNWRSNFGGSVWSRLPDGRWYYH
TFAKEQPDLNWECKELRQKIYEMINWWLEKGIAGFRIDAITFIKKDLSFASRPTNDGERYPVENLTDYKGIGTFLDEMKE
QCFDKYNCMTVAEAPGVDDAAFERYAGKNGYFSMIFDFGWENMEGENDKSSIHAVERWKKKMFTHVAHNSGIGWSAIFLE
NHDQSRCLNKFLERENISFYSASALASIYFFLYGTPFIYQGQEIGMTNVKWKNINDMDDIRAKRTYEEAVGQGKDPDEVL
AYFSELGRDNARTPMQWDDSENGGFTCGKPWIKCNDNYRTINAQSQVNDPDSLYNYYKRLIQCYHDHADIVRQAEFRPMY
EEYPGLFAYEREVNGKGLLVIVNFTNEKLMFQKIDQKCELCNYHETESEWLQPYEARIYSK

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=538, Percent_Identity=29.5539033457249, Blast_Score=214, Evalue=2e-55,
Organism=Escherichia coli, GI1790687, Length=555, Percent_Identity=37.4774774774775, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1786604, Length=375, Percent_Identity=24.2666666666667, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32565753, Length=553, Percent_Identity=24.4122965641953, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI25147709, Length=476, Percent_Identity=23.5294117647059, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322245, Length=573, Percent_Identity=36.4746945898778, Blast_Score=328, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6321726, Length=576, Percent_Identity=35.0694444444444, Blast_Score=301, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6324416, Length=576, Percent_Identity=35.7638888888889, Blast_Score=300, Evalue=4e-82,
Organism=Saccharomyces cerevisiae, GI6322241, Length=576, Percent_Identity=35.5902777777778, Blast_Score=300, Evalue=4e-82,
Organism=Saccharomyces cerevisiae, GI6322021, Length=576, Percent_Identity=35.5902777777778, Blast_Score=300, Evalue=4e-82,
Organism=Saccharomyces cerevisiae, GI6321731, Length=575, Percent_Identity=34.9565217391304, Blast_Score=297, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6319776, Length=572, Percent_Identity=35.1398601398601, Blast_Score=297, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24583749, Length=535, Percent_Identity=32.1495327102804, Blast_Score=251, Evalue=7e-67,
Organism=Drosophila melanogaster, GI24583747, Length=535, Percent_Identity=32.1495327102804, Blast_Score=251, Evalue=8e-67,
Organism=Drosophila melanogaster, GI24583745, Length=541, Percent_Identity=32.1626617375231, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586593, Length=486, Percent_Identity=33.7448559670782, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI221330053, Length=499, Percent_Identity=33.6673346693387, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586599, Length=569, Percent_Identity=29.8769771528998, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI45549022, Length=557, Percent_Identity=31.0592459605027, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24586597, Length=545, Percent_Identity=29.3577981651376, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24586589, Length=532, Percent_Identity=30.8270676691729, Blast_Score=218, Evalue=9e-57,
Organism=Drosophila melanogaster, GI24586591, Length=492, Percent_Identity=31.3008130081301, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24586587, Length=484, Percent_Identity=29.7520661157025, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI281360393, Length=433, Percent_Identity=31.1778290993072, Blast_Score=174, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 63694; Mature: 63694

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNWWKESVVYQIYPQSFMDSNGDGIGDFNGIIQKLDYLQNLGVDVLWICPMYASPLVD
CCCCCCCCCCEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHCCCCCC
NGYDISDYYKVNPIFGTNEDMEHLIEEAQKRKIKIILDLVVNHCSDQHEWFQKAMKDPNC
CCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
EEASYFYFRTTENDKEPNNWRSNFGGSVWSRLPDGRWYYHTFAKEQPDLNWECKELRQKI
CCCCEEEEEECCCCCCCCHHHHHCCCHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHH
YEMINWWLEKGIAGFRIDAITFIKKDLSFASRPTNDGERYPVENLTDYKGIGTFLDEMKE
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
QCFDKYNCMTVAEAPGVDDAAFERYAGKNGYFSMIFDFGWENMEGENDKSSIHAVERWKK
HHHHHCCCEEEECCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
KMFTHVAHNSGIGWSAIFLENHDQSRCLNKFLERENISFYSASALASIYFFLYGTPFIYQ
HHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEC
GQEIGMTNVKWKNINDMDDIRAKRTYEEAVGQGKDPDEVLAYFSELGRDNARTPMQWDDS
CCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
ENGGFTCGKPWIKCNDNYRTINAQSQVNDPDSLYNYYKRLIQCYHDHADIVRQAEFRPMY
CCCCEECCCCCEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EEYPGLFAYEREVNGKGLLVIVNFTNEKLMFQKIDQKCELCNYHETESEWLQPYEARIYS
HHCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHCC
K
C
>Mature Secondary Structure
MKNNWWKESVVYQIYPQSFMDSNGDGIGDFNGIIQKLDYLQNLGVDVLWICPMYASPLVD
CCCCCCCCCCEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHCCCCCC
NGYDISDYYKVNPIFGTNEDMEHLIEEAQKRKIKIILDLVVNHCSDQHEWFQKAMKDPNC
CCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
EEASYFYFRTTENDKEPNNWRSNFGGSVWSRLPDGRWYYHTFAKEQPDLNWECKELRQKI
CCCCEEEEEECCCCCCCCHHHHHCCCHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHH
YEMINWWLEKGIAGFRIDAITFIKKDLSFASRPTNDGERYPVENLTDYKGIGTFLDEMKE
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
QCFDKYNCMTVAEAPGVDDAAFERYAGKNGYFSMIFDFGWENMEGENDKSSIHAVERWKK
HHHHHCCCEEEECCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
KMFTHVAHNSGIGWSAIFLENHDQSRCLNKFLERENISFYSASALASIYFFLYGTPFIYQ
HHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEC
GQEIGMTNVKWKNINDMDDIRAKRTYEEAVGQGKDPDEVLAYFSELGRDNARTPMQWDDS
CCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
ENGGFTCGKPWIKCNDNYRTINAQSQVNDPDSLYNYYKRLIQCYHDHADIVRQAEFRPMY
CCCCEECCCCCEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EEYPGLFAYEREVNGKGLLVIVNFTNEKLMFQKIDQKCELCNYHETESEWLQPYEARIYS
HHCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]