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The map label for this gene is cisA [H]

Identifier: 238925870

GI number: 238925870

Start: 3298911

End: 3300602

Strand: Reverse

Name: cisA [H]

Synonym: EUBREC_3528

Alternate gene names: 238925870

Gene position: 3300602-3298911 (Counterclockwise)

Preceding gene: 238925871

Following gene: 238925869

Centisome position: 95.68

GC content: 41.61

Gene sequence:

>1692_bases
ATGGCACGAAAGAGCAGGAAAAACATTCCGGAAGTAGTCAGCAGTGCAACCGTCCAGACAGAGGTGAGCAGACCGTTCCG
GGCAGGATTGTATGCCAGAATTTCAATGGAAACAGAAGAAACCTTAGAAAGAGGAACGATAGAAACCCAGGTGGAACTGA
TGAAAAACTTTGTGGCAGATACGGAAGACATCGCAGTTGCAGAAATATATAAGGATTCTGATTATTCTGGTACAAATTTC
GACCGTCCTGGTTTTACGCAGATGATGGAAGATATCAAGCATGGAAAAATTAACTGTGTGATTGTAAAGGATCTATCCAG
ACTTGGAAGGAATTATGTAGAGACAAGTAATTATATTGAGCGTGTATTTCCGTTTTTTCATGTGCGGTTTCTTGCTGTGA
CGGATGACTTTGATTCTTTCCGTGAGGGAGTGGATCTGACAGTTCCCTTAAAAAATATCATCAATGAGTTTTATTCCAAA
GACCTTGCAAAAAAGAGCAGCAGTGCCAAAAAAGCCCTGTGGAAAGAAGGAAAATTTACTGGTGCATGGGAACCTTATGG
ATACAGGAAATCAGAACAGGACAGACACCAGCTGGTAGTTGACGAGGAGGCTGCCGGACATTTACGAGAAATTTTTACTA
TGTATATGGATGGATGCAGCTACAGCGATATTGCAAAAAGACTGAATACAGATGGTATCCTTTCCCCGACTTTGCAGAGG
GAATATTATAAAACAGGCGAAAAGCCTTCACCGGAATCCAAACCTTGGAATAATTATGAAGTGAAACGTGTACTTCAGGA
TGTCCATTGTACCGGAGATTCTGTATATGGAAAATATCAGCAGAGTGTTTTTCAAGGAAACAAGCAGAGAAATCTACCGG
AGAGTGAGTGGCTCTATGCTGAGAATACCCACGAAGGAATTATTGATAAAGAACTGTTCCGGCAGGTACAGGAAAAAATC
CGGGAATTTACGGAAGCATACAAAAAGAAGCATCAGCTGAATAATGGAGCCATTCGGAATCATAATTTCTATACCGGCAA
GATCAGGTGTGGGGGTTGTGGGAACCGCATGGTGTTGTCCAGAGAAAAAACAGGGACATTTTATTATATCTGTGGTGCAG
ATGCGAACCATAAATCCGGAGGAAATCAGTGTAAGGGGCACAGAGTCAAAAAAGAATACGTGGATGAAGACGTCCTTCGC
CTGATCCAGTCACATATGAAAGCCGTATTGGATACAGAGAAACTGATCCGTGAAATGAATTCTGCTTCCAGAAACCAGAC
ACAGTATTTGCTTCTGGATAAGGAAGTGGGGAAACTTCGGCGGGAGTTGAGCAGGATCAGCAAGCGTAAATCTGATTTAT
ATGAGGATTATTCGGAACGTCTGATTACAGAAGAAGAATACATGCAGTTTTCCCGTATCTATTCCAATGAAATAGAAAAC
ATCAAGAACCGCCTGGATGTAGTATTGGCGGCACAGGTACGGTATTCCAAGGATTATCATATCGAGGAAGGATGGGGAAA
AGTGATACATACTTATATGTCAAAGCGTAAGCTGACAAAAGAAATGGCAGATGCCTTTGTGGATTCAATTATTATCCATG
GTAAGTATGATTATGAGATCAAGCTGGTATATGACGATCAGTTTGCAGATTTACAGAAATTAAAGAAAGAGAAGGAGGCG
CAGTCAAGATGA

Upstream 100 bases:

>100_bases
TGTTATCAGACATTGCTGAATCAATTACCTGCTATGGGAGTTGATATGGTAATAGATGATGATAACAATCTGCAGGTCAA
TGTAAAGGAGGTTGTATAAA

Downstream 100 bases:

>100_bases
CAGATCATAGAAAAACAGCTGTTTACATCCGTTTATCCGCAGAAGATGACAATGTAGATGGCAGAGCTAAAAAAGAGAGC
GACAGTGTAACTTCTCAGAG

Product: cassette chromosome recombinase B

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MARKSRKNIPEVVSSATVQTEVSRPFRAGLYARISMETEETLERGTIETQVELMKNFVADTEDIAVAEIYKDSDYSGTNF
DRPGFTQMMEDIKHGKINCVIVKDLSRLGRNYVETSNYIERVFPFFHVRFLAVTDDFDSFREGVDLTVPLKNIINEFYSK
DLAKKSSSAKKALWKEGKFTGAWEPYGYRKSEQDRHQLVVDEEAAGHLREIFTMYMDGCSYSDIAKRLNTDGILSPTLQR
EYYKTGEKPSPESKPWNNYEVKRVLQDVHCTGDSVYGKYQQSVFQGNKQRNLPESEWLYAENTHEGIIDKELFRQVQEKI
REFTEAYKKKHQLNNGAIRNHNFYTGKIRCGGCGNRMVLSREKTGTFYYICGADANHKSGGNQCKGHRVKKEYVDEDVLR
LIQSHMKAVLDTEKLIREMNSASRNQTQYLLLDKEVGKLRRELSRISKRKSDLYEDYSERLITEEEYMQFSRIYSNEIEN
IKNRLDVVLAAQVRYSKDYHIEEGWGKVIHTYMSKRKLTKEMADAFVDSIIIHGKYDYEIKLVYDDQFADLQKLKKEKEA
QSR

Sequences:

>Translated_563_residues
MARKSRKNIPEVVSSATVQTEVSRPFRAGLYARISMETEETLERGTIETQVELMKNFVADTEDIAVAEIYKDSDYSGTNF
DRPGFTQMMEDIKHGKINCVIVKDLSRLGRNYVETSNYIERVFPFFHVRFLAVTDDFDSFREGVDLTVPLKNIINEFYSK
DLAKKSSSAKKALWKEGKFTGAWEPYGYRKSEQDRHQLVVDEEAAGHLREIFTMYMDGCSYSDIAKRLNTDGILSPTLQR
EYYKTGEKPSPESKPWNNYEVKRVLQDVHCTGDSVYGKYQQSVFQGNKQRNLPESEWLYAENTHEGIIDKELFRQVQEKI
REFTEAYKKKHQLNNGAIRNHNFYTGKIRCGGCGNRMVLSREKTGTFYYICGADANHKSGGNQCKGHRVKKEYVDEDVLR
LIQSHMKAVLDTEKLIREMNSASRNQTQYLLLDKEVGKLRRELSRISKRKSDLYEDYSERLITEEEYMQFSRIYSNEIEN
IKNRLDVVLAAQVRYSKDYHIEEGWGKVIHTYMSKRKLTKEMADAFVDSIIIHGKYDYEIKLVYDDQFADLQKLKKEKEA
QSR
>Mature_562_residues
ARKSRKNIPEVVSSATVQTEVSRPFRAGLYARISMETEETLERGTIETQVELMKNFVADTEDIAVAEIYKDSDYSGTNFD
RPGFTQMMEDIKHGKINCVIVKDLSRLGRNYVETSNYIERVFPFFHVRFLAVTDDFDSFREGVDLTVPLKNIINEFYSKD
LAKKSSSAKKALWKEGKFTGAWEPYGYRKSEQDRHQLVVDEEAAGHLREIFTMYMDGCSYSDIAKRLNTDGILSPTLQRE
YYKTGEKPSPESKPWNNYEVKRVLQDVHCTGDSVYGKYQQSVFQGNKQRNLPESEWLYAENTHEGIIDKELFRQVQEKIR
EFTEAYKKKHQLNNGAIRNHNFYTGKIRCGGCGNRMVLSREKTGTFYYICGADANHKSGGNQCKGHRVKKEYVDEDVLRL
IQSHMKAVLDTEKLIREMNSASRNQTQYLLLDKEVGKLRRELSRISKRKSDLYEDYSERLITEEEYMQFSRIYSNEIENI
KNRLDVVLAAQVRYSKDYHIEEGWGKVIHTYMSKRKLTKEMADAFVDSIIIHGKYDYEIKLVYDDQFADLQKLKKEKEAQ
SR

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 65679; Mature: 65548

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKSRKNIPEVVSSATVQTEVSRPFRAGLYARISMETEETLERGTIETQVELMKNFVAD
CCCCCCCCCHHHHHHHHHHHHHCCCHHCCCEEEEECCHHHHHHHCCHHHHHHHHHHHHCC
TEDIAVAEIYKDSDYSGTNFDRPGFTQMMEDIKHGKINCVIVKDLSRLGRNYVETSNYIE
CCCHHHHHHEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEHHHHHHCHHHHHHHHHHH
RVFPFFHVRFLAVTDDFDSFREGVDLTVPLKNIINEFYSKDLAKKSSSAKKALWKEGKFT
HHHHHHHEEEEEEECCHHHHHCCCCEEECHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
GAWEPYGYRKSEQDRHQLVVDEEAAGHLREIFTMYMDGCSYSDIAKRLNTDGILSPTLQR
CCCCCCCCCCCCCCHHCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHH
EYYKTGEKPSPESKPWNNYEVKRVLQDVHCTGDSVYGKYQQSVFQGNKQRNLPESEWLYA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHCEEE
ENTHEGIIDKELFRQVQEKIREFTEAYKKKHQLNNGAIRNHNFYTGKIRCGGCGNRMVLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCEEEEEEEECCCCCCEEEE
REKTGTFYYICGADANHKSGGNQCKGHRVKKEYVDEDVLRLIQSHMKAVLDTEKLIREMN
ECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SASRNQTQYLLLDKEVGKLRRELSRISKRKSDLYEDYSERLITEEEYMQFSRIYSNEIEN
HCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IKNRLDVVLAAQVRYSKDYHIEEGWGKVIHTYMSKRKLTKEMADAFVDSIIIHGKYDYEI
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEE
KLVYDDQFADLQKLKKEKEAQSR
EEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARKSRKNIPEVVSSATVQTEVSRPFRAGLYARISMETEETLERGTIETQVELMKNFVAD
CCCCCCCCHHHHHHHHHHHHHCCCHHCCCEEEEECCHHHHHHHCCHHHHHHHHHHHHCC
TEDIAVAEIYKDSDYSGTNFDRPGFTQMMEDIKHGKINCVIVKDLSRLGRNYVETSNYIE
CCCHHHHHHEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEHHHHHHCHHHHHHHHHHH
RVFPFFHVRFLAVTDDFDSFREGVDLTVPLKNIINEFYSKDLAKKSSSAKKALWKEGKFT
HHHHHHHEEEEEEECCHHHHHCCCCEEECHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
GAWEPYGYRKSEQDRHQLVVDEEAAGHLREIFTMYMDGCSYSDIAKRLNTDGILSPTLQR
CCCCCCCCCCCCCCHHCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHH
EYYKTGEKPSPESKPWNNYEVKRVLQDVHCTGDSVYGKYQQSVFQGNKQRNLPESEWLYA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHCEEE
ENTHEGIIDKELFRQVQEKIREFTEAYKKKHQLNNGAIRNHNFYTGKIRCGGCGNRMVLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCEEEEEEEECCCCCCEEEE
REKTGTFYYICGADANHKSGGNQCKGHRVKKEYVDEDVLRLIQSHMKAVLDTEKLIREMN
ECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SASRNQTQYLLLDKEVGKLRRELSRISKRKSDLYEDYSERLITEEEYMQFSRIYSNEIEN
HCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IKNRLDVVLAAQVRYSKDYHIEEGWGKVIHTYMSKRKLTKEMADAFVDSIIIHGKYDYEI
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEE
KLVYDDQFADLQKLKKEKEAQSR
EEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]