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The map label for this gene is speA [H]

Identifier: 238925688

GI number: 238925688

Start: 3167133

End: 3168584

Strand: Reverse

Name: speA [H]

Synonym: EUBREC_3345

Alternate gene names: 238925688

Gene position: 3168584-3167133 (Counterclockwise)

Preceding gene: 238925689

Following gene: 238925687

Centisome position: 91.85

GC content: 48.0

Gene sequence:

>1452_bases
ATGGATATCAAAAGACAGGAAAGAGCGCCGATTTATGAGGCTCTTGAGGAGTTTAAGAAGAAGAGAGTGGTGCCGTTTGA
TGTGCCGGGACACAAGAGAGGCAGGGGAAATCCTGAGCTGGTGCATCTGCTCGGAGAAAAGTGTGTAGGGCTTGATGTCA
ATTCAATGAAGCCGCTTGACAATTTGTGCCATCCGGTTTCGGTAATCAGAGAGGCGGAGGAGCTTGCGGCGGATGCATTT
GGAGCGGCAAATGCTTTTCTTATGGTAGGAGGCACCACCTCTGCGGTGCAGGCCATGATTTTGTCCACCTGCAAGGCAGG
AGACAAGATTATACTTCCGAGAAATGTTCATAAAAGTGCTCTTAATGCACTCGTGCTCTGCGGAGCGATACCTGTTTATG
TCAATCCGCAGACGAATGCGAAGCTTGGTATTTCGCTTGGAATGGAGATTGACCAGGTGGCGAGGGCTATCGAGGAGAAT
CCGGATGCAAAGGCTGTGCTTGTAAACAATCCGACATATTATGGAATCTGTTCTGACCTTAAGTCGATAGTTGCGCTGGC
TCATTCGAAGGGAATCAAGGTGCTCACGGATGAGGCACATGGTACACATCTTTATTTTGGAAAGGGGCTTCCGATATCAG
GAATGGCAGCCGGGGCAGACATGTCTGCGGTATCGATGCACAAATCGGGAGGAAGCCTGACACAGAGCTCGATTCTGCTC
ACCGGAAGGGATGTGAATGCTGATTATGTGAGGCAGATTATCAACCTCACACAGACCACGAGCGCATCGTATCTGCTATT
GTCAAGCCTTGATATATCAAGAAGAAATCTGGCACTCAGAGGCGAGGAATCCTTTGCCAAGGTGGCACAGATGTCGGAGT
ATGCAAGGCAGGAGATTAATTCCATAGGCGGCTATTATGCGTATGGGCGTGACCTTGTAAATGGCACGAGCATATATGAT
TATGATGTGACAAAGCTGTCCATCTATACGCTCGATATAGGGCTTGCCGGAATAGAGGTATATGATCTGCTGCGTGATGA
GTATGATATCCAGATAGAGTTTGGAGATATCTGTAATATACTTGCGTATATATCAATTGGCGACAGAATACAGGATATAG
AGAGGCTTGTAGGTGCGCTGGAGGATATCAAGCGCCTTTACAGCAAGGACAAGACCGGACTTTTGTCGGGAGAGTACATA
AATCCAAAGGTGGCGGTATCGCCGCAGGAGGCGTTTTATTCGCAGAAGAAATCAGTGCGCATTATGGACGCGGTAGGTGC
TGTAAGTGGTGAGTTTGTCATGTGTTATCCACCGGGAATCCCGATTCTTGCACCGGGAGAGCTTATCACAAAAGAGATTG
CGCAATACATTGTCTACGCAAAGGAAAAGGGCTGTTCAATGCAGGGAACAGAGGATCCTGCGGTAGAATATCTTAAGGTA
TTGGAGCAGTAA

Upstream 100 bases:

>100_bases
TGCATAACTCCATAGTATATGTTACGATTTTACTGTTGTTAAGACGAATCTAAAGGATGATGCTTGCACGCATCATCCTT
TTTAAATACAGGAGAAGTAA

Downstream 100 bases:

>100_bases
ACAGGAGGAAAAGCTATGCAAATGTGGTTTTCACAATATCATACTGTCAATGTCAAGCTGGATGTAAGGATACAGGAGCA
GCTTTTTTCAGGGCAGAGTG

Product: lysine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MDIKRQERAPIYEALEEFKKKRVVPFDVPGHKRGRGNPELVHLLGEKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAF
GAANAFLMVGGTTSAVQAMILSTCKAGDKIILPRNVHKSALNALVLCGAIPVYVNPQTNAKLGISLGMEIDQVARAIEEN
PDAKAVLVNNPTYYGICSDLKSIVALAHSKGIKVLTDEAHGTHLYFGKGLPISGMAAGADMSAVSMHKSGGSLTQSSILL
TGRDVNADYVRQIINLTQTTSASYLLLSSLDISRRNLALRGEESFAKVAQMSEYARQEINSIGGYYAYGRDLVNGTSIYD
YDVTKLSIYTLDIGLAGIEVYDLLRDEYDIQIEFGDICNILAYISIGDRIQDIERLVGALEDIKRLYSKDKTGLLSGEYI
NPKVAVSPQEAFYSQKKSVRIMDAVGAVSGEFVMCYPPGIPILAPGELITKEIAQYIVYAKEKGCSMQGTEDPAVEYLKV
LEQ

Sequences:

>Translated_483_residues
MDIKRQERAPIYEALEEFKKKRVVPFDVPGHKRGRGNPELVHLLGEKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAF
GAANAFLMVGGTTSAVQAMILSTCKAGDKIILPRNVHKSALNALVLCGAIPVYVNPQTNAKLGISLGMEIDQVARAIEEN
PDAKAVLVNNPTYYGICSDLKSIVALAHSKGIKVLTDEAHGTHLYFGKGLPISGMAAGADMSAVSMHKSGGSLTQSSILL
TGRDVNADYVRQIINLTQTTSASYLLLSSLDISRRNLALRGEESFAKVAQMSEYARQEINSIGGYYAYGRDLVNGTSIYD
YDVTKLSIYTLDIGLAGIEVYDLLRDEYDIQIEFGDICNILAYISIGDRIQDIERLVGALEDIKRLYSKDKTGLLSGEYI
NPKVAVSPQEAFYSQKKSVRIMDAVGAVSGEFVMCYPPGIPILAPGELITKEIAQYIVYAKEKGCSMQGTEDPAVEYLKV
LEQ
>Mature_483_residues
MDIKRQERAPIYEALEEFKKKRVVPFDVPGHKRGRGNPELVHLLGEKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAF
GAANAFLMVGGTTSAVQAMILSTCKAGDKIILPRNVHKSALNALVLCGAIPVYVNPQTNAKLGISLGMEIDQVARAIEEN
PDAKAVLVNNPTYYGICSDLKSIVALAHSKGIKVLTDEAHGTHLYFGKGLPISGMAAGADMSAVSMHKSGGSLTQSSILL
TGRDVNADYVRQIINLTQTTSASYLLLSSLDISRRNLALRGEESFAKVAQMSEYARQEINSIGGYYAYGRDLVNGTSIYD
YDVTKLSIYTLDIGLAGIEVYDLLRDEYDIQIEFGDICNILAYISIGDRIQDIERLVGALEDIKRLYSKDKTGLLSGEYI
NPKVAVSPQEAFYSQKKSVRIMDAVGAVSGEFVMCYPPGIPILAPGELITKEIAQYIVYAKEKGCSMQGTEDPAVEYLKV
LEQ

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=542, Percent_Identity=24.169741697417, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790573, Length=569, Percent_Identity=22.4956063268893, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI221142684, Length=303, Percent_Identity=26.7326732673267, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 52559; Mature: 52559

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKRQERAPIYEALEEFKKKRVVPFDVPGHKRGRGNPELVHLLGEKCVGLDVNSMKPLD
CCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHH
NLCHPVSVIREAEELAADAFGAANAFLMVGGTTSAVQAMILSTCKAGDKIILPRNVHKSA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCHHHHH
LNALVLCGAIPVYVNPQTNAKLGISLGMEIDQVARAIEENPDAKAVLVNNPTYYGICSDL
HHHHHHHCCCEEEECCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCEEHHHHHH
KSIVALAHSKGIKVLTDEAHGTHLYFGKGLPISGMAAGADMSAVSMHKSGGSLTQSSILL
HHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHEEECCCCCCEECEEEE
TGRDVNADYVRQIINLTQTTSASYLLLSSLDISRRNLALRGEESFAKVAQMSEYARQEIN
ECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
SIGGYYAYGRDLVNGTSIYDYDVTKLSIYTLDIGLAGIEVYDLLRDEYDIQIEFGDICNI
HCCCEEHHCHHHCCCCEEEEECCEEEEEEEEEECCCHHHHHHHHCCCEEEEEEHHHHHHH
LAYISIGDRIQDIERLVGALEDIKRLYSKDKTGLLSGEYINPKVAVSPQEAFYSQKKSVR
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHCCCEE
IMDAVGAVSGEFVMCYPPGIPILAPGELITKEIAQYIVYAKEKGCSMQGTEDPAVEYLKV
EEHHHCCCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LEQ
HCC
>Mature Secondary Structure
MDIKRQERAPIYEALEEFKKKRVVPFDVPGHKRGRGNPELVHLLGEKCVGLDVNSMKPLD
CCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHH
NLCHPVSVIREAEELAADAFGAANAFLMVGGTTSAVQAMILSTCKAGDKIILPRNVHKSA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCHHHHH
LNALVLCGAIPVYVNPQTNAKLGISLGMEIDQVARAIEENPDAKAVLVNNPTYYGICSDL
HHHHHHHCCCEEEECCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEECCCCEEHHHHHH
KSIVALAHSKGIKVLTDEAHGTHLYFGKGLPISGMAAGADMSAVSMHKSGGSLTQSSILL
HHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHEEECCCCCCEECEEEE
TGRDVNADYVRQIINLTQTTSASYLLLSSLDISRRNLALRGEESFAKVAQMSEYARQEIN
ECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
SIGGYYAYGRDLVNGTSIYDYDVTKLSIYTLDIGLAGIEVYDLLRDEYDIQIEFGDICNI
HCCCEEHHCHHHCCCCEEEEECCEEEEEEEEEECCCHHHHHHHHCCCEEEEEEHHHHHHH
LAYISIGDRIQDIERLVGALEDIKRLYSKDKTGLLSGEYINPKVAVSPQEAFYSQKKSVR
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHCCCEE
IMDAVGAVSGEFVMCYPPGIPILAPGELITKEIAQYIVYAKEKGCSMQGTEDPAVEYLKV
EEHHHCCCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LEQ
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]