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The map label for this gene is aroE [H]

Identifier: 238925196

GI number: 238925196

Start: 2732557

End: 2733426

Strand: Reverse

Name: aroE [H]

Synonym: EUBREC_2850

Alternate gene names: 238925196

Gene position: 2733426-2732557 (Counterclockwise)

Preceding gene: 238925199

Following gene: 238925194

Centisome position: 79.24

GC content: 45.4

Gene sequence:

>870_bases
ATGGAAAAGCGTATTTCAGGTCACACAGGCTTATTAGCACTCATAGGATCACCTGTCGGTCATTCGGGTTCACCGGCTAT
GTACAATTACAGTTTTGAAAAACTCGGTCTGGACTATGCATACGTTGCATTTGATATAAAAGAAGACAAGGTTAAGGATG
CTATTGCAGCAATGAAGACCTTCAACATGCGTGGATGTAATGTGACCATGCCTGATAAGGTAGAGGCTGCAAAGTACATG
GACGAGCTTTCACCGGCAGCCCAGATTATCGGAGCCATAAACACTATAGTAAATGACAACGGCAAGCTTACAGGACACAT
CACAGATGGTGAGGGATTCGTACACAACTTAAAGGATCACGGAATTGACATCAAAGGAAAGAAAATCACAGTTGCCGGAG
GCGGCGGAGCCGCTACAGCTATCCAGGTGCAGTGCGCATTGGACGGAGCTCGTGAGATTACTATTTTCAACAAAAATGAT
GCTTTCTTTGAGCGTACACTACAGACTGCAGAGAAGATCAAAAAAGCAGTTCCTGAATGTGTTGTAAATGTATACGATAT
TGATGATACAGCCAAGATGACAGAGGAAATCCAGTCAAGCGATATCTTTGCAAATGCAACAATCGTTGGCATGAAGCCTC
TGGATGATCAGAGCGTGGTAAAAGATCTTTCAGCTTTCAGACCGGGGCTTGTAGTTGCAGATGCAGTTTACAATCCGGAG
GAGACAAAGCTTCTTCGCGAAGCAAAAGAGGCAGGCTGCACATGCGTAGGCGGAAAGGGAATGCTCTTATGGCAGGGCGT
CGCCGCATTCAAGCTTTACACAGGACAGGATATGCCGGTTGATGATGTGAAGAAACTGTTCTTCAGTTAG

Upstream 100 bases:

>100_bases
TAAACTTTAACACTTTAAACCTTTAAATGAAAAAAGTGCTTGCGCATGTCTTATAAAAGAGTTATCATAATACAAAACGA
AACACTTAGGAGGATTTACA

Downstream 100 bases:

>100_bases
ATTTAAGTTCTTATTACAATATCATTAGATAGCTTCCTGTTATACAGGAATATGATAAAACAACAGCTCGCGGTTTCCCG
CGAGCTGTTGTTTTTTAGGA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MEKRISGHTGLLALIGSPVGHSGSPAMYNYSFEKLGLDYAYVAFDIKEDKVKDAIAAMKTFNMRGCNVTMPDKVEAAKYM
DELSPAAQIIGAINTIVNDNGKLTGHITDGEGFVHNLKDHGIDIKGKKITVAGGGGAATAIQVQCALDGAREITIFNKND
AFFERTLQTAEKIKKAVPECVVNVYDIDDTAKMTEEIQSSDIFANATIVGMKPLDDQSVVKDLSAFRPGLVVADAVYNPE
ETKLLREAKEAGCTCVGGKGMLLWQGVAAFKLYTGQDMPVDDVKKLFFS

Sequences:

>Translated_289_residues
MEKRISGHTGLLALIGSPVGHSGSPAMYNYSFEKLGLDYAYVAFDIKEDKVKDAIAAMKTFNMRGCNVTMPDKVEAAKYM
DELSPAAQIIGAINTIVNDNGKLTGHITDGEGFVHNLKDHGIDIKGKKITVAGGGGAATAIQVQCALDGAREITIFNKND
AFFERTLQTAEKIKKAVPECVVNVYDIDDTAKMTEEIQSSDIFANATIVGMKPLDDQSVVKDLSAFRPGLVVADAVYNPE
ETKLLREAKEAGCTCVGGKGMLLWQGVAAFKLYTGQDMPVDDVKKLFFS
>Mature_289_residues
MEKRISGHTGLLALIGSPVGHSGSPAMYNYSFEKLGLDYAYVAFDIKEDKVKDAIAAMKTFNMRGCNVTMPDKVEAAKYM
DELSPAAQIIGAINTIVNDNGKLTGHITDGEGFVHNLKDHGIDIKGKKITVAGGGGAATAIQVQCALDGAREITIFNKND
AFFERTLQTAEKIKKAVPECVVNVYDIDDTAKMTEEIQSSDIFANATIVGMKPLDDQSVVKDLSAFRPGLVVADAVYNPE
ETKLLREAKEAGCTCVGGKGMLLWQGVAAFKLYTGQDMPVDDVKKLFFS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=277, Percent_Identity=47.2924187725632, Blast_Score=280, Evalue=7e-77,
Organism=Escherichia coli, GI1789675, Length=277, Percent_Identity=28.158844765343, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320332, Length=280, Percent_Identity=30.7142857142857, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 31154; Mature: 31154

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRISGHTGLLALIGSPVGHSGSPAMYNYSFEKLGLDYAYVAFDIKEDKVKDAIAAMKT
CCCCCCCCCCEEEEECCCCCCCCCCCEEECCHHHHCCCEEEEEEECCHHHHHHHHHHHHH
FNMRGCNVTMPDKVEAAKYMDELSPAAQIIGAINTIVNDNGKLTGHITDGEGFVHNLKDH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEHHHHC
GIDIKGKKITVAGGGGAATAIQVQCALDGAREITIFNKNDAFFERTLQTAEKIKKAVPEC
CCCCCCCEEEEECCCCCEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
VVNVYDIDDTAKMTEEIQSSDIFANATIVGMKPLDDQSVVKDLSAFRPGLVVADAVYNPE
EEEEECCCCHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCH
ETKLLREAKEAGCTCVGGKGMLLWQGVAAFKLYTGQDMPVDDVKKLFFS
HHHHHHHHHHCCCEEECCCCEEEECCCEEEEEECCCCCCHHHHHHHHCC
>Mature Secondary Structure
MEKRISGHTGLLALIGSPVGHSGSPAMYNYSFEKLGLDYAYVAFDIKEDKVKDAIAAMKT
CCCCCCCCCCEEEEECCCCCCCCCCCEEECCHHHHCCCEEEEEEECCHHHHHHHHHHHHH
FNMRGCNVTMPDKVEAAKYMDELSPAAQIIGAINTIVNDNGKLTGHITDGEGFVHNLKDH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEHHHHC
GIDIKGKKITVAGGGGAATAIQVQCALDGAREITIFNKNDAFFERTLQTAEKIKKAVPEC
CCCCCCCEEEEECCCCCEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
VVNVYDIDDTAKMTEEIQSSDIFANATIVGMKPLDDQSVVKDLSAFRPGLVVADAVYNPE
EEEEECCCCHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCH
ETKLLREAKEAGCTCVGGKGMLLWQGVAAFKLYTGQDMPVDDVKKLFFS
HHHHHHHHHHCCCEEECCCCEEEECCCEEEEEECCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]