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The map label for this gene is aroD [H]

Identifier: 238925187

GI number: 238925187

Start: 2722937

End: 2723698

Strand: Reverse

Name: aroD [H]

Synonym: EUBREC_2841

Alternate gene names: 238925187

Gene position: 2723698-2722937 (Counterclockwise)

Preceding gene: 238925188

Following gene: 238925186

Centisome position: 78.95

GC content: 44.49

Gene sequence:

>762_bases
ATGAACACCATTAAGGTTAGAGATATTGAAATCGGTGCAGGCGCACCTAAAATCATCGTTCCTATCGTAGGCGTTACAAA
AGACGACATCATCGCAGAGGCAAAGACATTTGACTCTATCCCTGTTGATATGGTTGAGTGGCGTGTTGACTGGTTCGAGA
ATGTATTCGAGTTTGACAAGGTTGAGGAGGTATTAAAGGAGCTTCGTGATGCTCTCGGAAATATTCCAATCCTTATGACA
TTCCGTACTTCAAAAGAGGGCGGAGAGAAAGCAATCGAGCCTGAGGCTTATGCCAGGCTTAATGTCAAGGCTGCACAGAC
AGGATACGTTGATTTTGTAGATGTAGAGATTTTTACAGGCGATGAGATTGTAAAGAAAATCATCGACGGCGTACATGCTG
CAGGTGCAAGAGTTATCGCTTCAAACCATGATTTCTTCAAGACTCCTGCACAGTCTGATATTGTTTACAGACTTCGCAAG
ATGCAGGATATGGGAGCTGATATCCCTAAGATTGCAGTTATGCCACAGAATAAGCGAGACGTACTCACACTTCTTTCAGC
TACAGAGGAAATGGTTACAGATTACGCTGACAGACCAATCATCACAATGTCAATGGCAGGCACAGGTGTTATAAGCCGTC
TCTGCGGTGAGGTATTCGGATCTTCAATGACATTCGGTGCCGCAAAGAAAGCATCTGCACCCGGACAGATGGGAGTAGAG
GATCTGTCTACGGTACTTGGATTACTTCATAAGAGCATGTAA

Upstream 100 bases:

>100_bases
CGCTATACTAAGATGGTAGAGCTGTCTAAAGAGGATTAATACGTTACATTATACTGGGGAGTATAATTATCATACAGTTA
AAGTAAGAAAGGAAAAAATC

Downstream 100 bases:

>100_bases
TTGATTGTGCATTAAGTAAAAGCCTGTTGCATGTAAAAAGTGCAATAGGCTTTTTATTAAAATATCTAAAATTTACATAT
TCTTGTAGGAAAATTAATTT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MNTIKVRDIEIGAGAPKIIVPIVGVTKDDIIAEAKTFDSIPVDMVEWRVDWFENVFEFDKVEEVLKELRDALGNIPILMT
FRTSKEGGEKAIEPEAYARLNVKAAQTGYVDFVDVEIFTGDEIVKKIIDGVHAAGARVIASNHDFFKTPAQSDIVYRLRK
MQDMGADIPKIAVMPQNKRDVLTLLSATEEMVTDYADRPIITMSMAGTGVISRLCGEVFGSSMTFGAAKKASAPGQMGVE
DLSTVLGLLHKSM

Sequences:

>Translated_253_residues
MNTIKVRDIEIGAGAPKIIVPIVGVTKDDIIAEAKTFDSIPVDMVEWRVDWFENVFEFDKVEEVLKELRDALGNIPILMT
FRTSKEGGEKAIEPEAYARLNVKAAQTGYVDFVDVEIFTGDEIVKKIIDGVHAAGARVIASNHDFFKTPAQSDIVYRLRK
MQDMGADIPKIAVMPQNKRDVLTLLSATEEMVTDYADRPIITMSMAGTGVISRLCGEVFGSSMTFGAAKKASAPGQMGVE
DLSTVLGLLHKSM
>Mature_253_residues
MNTIKVRDIEIGAGAPKIIVPIVGVTKDDIIAEAKTFDSIPVDMVEWRVDWFENVFEFDKVEEVLKELRDALGNIPILMT
FRTSKEGGEKAIEPEAYARLNVKAAQTGYVDFVDVEIFTGDEIVKKIIDGVHAAGARVIASNHDFFKTPAQSDIVYRLRK
MQDMGADIPKIAVMPQNKRDVLTLLSATEEMVTDYADRPIITMSMAGTGVISRLCGEVFGSSMTFGAAKKASAPGQMGVE
DLSTVLGLLHKSM

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family [H]

Homologues:

Organism=Escherichia coli, GI1787984, Length=252, Percent_Identity=54.3650793650794, Blast_Score=276, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6320332, Length=242, Percent_Identity=28.099173553719, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018508
- InterPro:   IPR013785
- InterPro:   IPR001381 [H]

Pfam domain/function: PF01487 DHquinase_I [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 27715; Mature: 27715

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIKVRDIEIGAGAPKIIVPIVGVTKDDIIAEAKTFDSIPVDMVEWRVDWFENVFEFDK
CCCEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VEEVLKELRDALGNIPILMTFRTSKEGGEKAIEPEAYARLNVKAAQTGYVDFVDVEIFTG
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHEEEEEECCCCCEEEEEEEEECC
DEIVKKIIDGVHAAGARVIASNHDFFKTPAQSDIVYRLRKMQDMGADIPKIAVMPQNKRD
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHH
VLTLLSATEEMVTDYADRPIITMSMAGTGVISRLCGEVFGSSMTFGAAKKASAPGQMGVE
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
DLSTVLGLLHKSM
HHHHHHHHHHHCC
>Mature Secondary Structure
MNTIKVRDIEIGAGAPKIIVPIVGVTKDDIIAEAKTFDSIPVDMVEWRVDWFENVFEFDK
CCCEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VEEVLKELRDALGNIPILMTFRTSKEGGEKAIEPEAYARLNVKAAQTGYVDFVDVEIFTG
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHEEEEEECCCCCEEEEEEEEECC
DEIVKKIIDGVHAAGARVIASNHDFFKTPAQSDIVYRLRKMQDMGADIPKIAVMPQNKRD
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHH
VLTLLSATEEMVTDYADRPIITMSMAGTGVISRLCGEVFGSSMTFGAAKKASAPGQMGVE
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
DLSTVLGLLHKSM
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA