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The map label for this gene is abcA [H]

Identifier: 238925114

GI number: 238925114

Start: 2642497

End: 2644410

Strand: Reverse

Name: abcA [H]

Synonym: EUBREC_2767

Alternate gene names: 238925114

Gene position: 2644410-2642497 (Counterclockwise)

Preceding gene: 238925115

Following gene: 238925113

Centisome position: 76.66

GC content: 37.62

Gene sequence:

>1914_bases
ATGAGAAAGATAGTATTAAACAAGATAGTATACGCAGTTGCAGTTATGTGCATGGTAATCACAATATTATATTGTCCTAC
AGATGTTTATGCTGCAACGGGGAGTGTTACATTTGGTTCAGAGAGTTACGAGGCACGGGATAATTCACAATTTCAGGTAG
GTGTATATCTGAAAACAAAATCAAAAATGGGATCTTATCATGTTGAAGTGGAATATGATAAATCACGGATGGAGTATACC
GGAGGTGCTGAATCGGAATCAAACGGTGTGATAACTCTCGAGGGAATTGGAGTGTCAGATCAGATAAAATATATGCTTTC
ATTCAAAACGATAAGTGGTGGTGATGCCTACATAAAGGTAAAGAACGCATATATATATACCTCCGATGCCAATAGTACAG
AACAGTTTGACATGACTGAACTGGATGAGGCAGGAATCACAATAGAAGGAGAGGATACAGGCACACCACGAACAGAAGAA
CCGACGGAATATGTTGGACCATTCGAGACCGATATTCCACATCTTGAACCTTCAATTAAACTTAATGATACAGATTATTA
TGTTGTTGACTCGAATCAGTATGTTCCTGAGAGTGTTAGCTGGAAATATGTGCTTGTTCCTGGAAAGCTTGGGAATATGG
ATGTGACGTTTTATTCAAATGAAGCACAAGATATATTTTTCCTTTCGTTAGTGGATTCTAACGGTGAGACACATTTATAT
AGTTACAGTAACTCGCAGAAACAGTTGTATGAGTGCAATTTCTATAATACAGGTAATACTATTTATTATTATACATCTCC
ATATGCCAGCGATAGCTGGCCGGAAGGCTTGACAGAAGATGTTATCAAAAAGCAGAATATATGCTATGCCCTTAGAAGTG
ATGGAGAGAGTGGCTTTTATAAGGTTGAAGCAGACAAGCTTACACTGTGGAATGTAGATGAAAATATTGCAGACGCAAAG
CCGATGACCGGAAAATTGATATTCATAATGATAATTGCAATTATTACGGGATTGGCACTCATTGTGTTAGTTTATTTTTG
GGGGCGTGAAGTTGGCAGAGCAAGACGCAAAAAGAAAAATTCTAAGAAGAAAAGGGTCATTGTAAGTAATGATATAAAGC
AGATCAAGAATGATGATGTAGAGAAGACAGAGAATCACTTGAATGAAAAAGGCGAGGAACCTATAATATCAGTTCAGGAT
GTAACTATGAAGTTTAAAATTTCTAACAGTAGTGCTTCAGGAATGAAGGATTTCCTTATTCAGAAATTAAAGCATCAGAT
AAATTATCGTGAGCTGTATGCTTTGGATCATGTTAGTTTTGATGTATATAAGGGCGAGGTTGTTGGTATAATCGGAACAA
ATGGTTCGGGAAAGAGTACGATGCTCAGGATAGTATCAGGTGCTCTTAATCCATCAGGTGGTAAAGTAGTGGTTGATAGA
AGAAAAGTTCAGCTTCTTACACTTGGAACCGGATTTGATATGGAGCTTACTGCTAGAGAAAATATATATCTCAATGGTGC
AATCATTGGATACAGTAAAAAATTTATAGATGAGCATTTTGATGAAATTATAGATTTTGCAGAATTGCAGGATTTCGTAG
ATGAGAAAGTGAAGAATTTCTCAAGTGGTATGGTCAGCAGACTTGGATTTGCAATAGCAACAGCAGGAGATGCGGCTGAA
ATCCTTATACTGGATGAGGTGCTTTCTGTAGGAGATGAATTTTTCAGAAAGAAGAGTCTTGCACGAGTTAAGGAAATGAT
ACATGGAGGCTCAACTGTACTGATGGTAAGTCATGGCATGGGAACAATTCTTGATAACTGTTCAAAGGTTGTATGGATAG
AGAAAGGAAAGCTTCAGATGGTAGGAGATCCGAAGACCGTTTGTGCAGCATATAGGAAACAGCAAAATGTATAG

Upstream 100 bases:

>100_bases
GTATTGTGCGCTTGGGGGAAAGTGTGGATAGAAGCCTGCGTTCAGCAGAGCAATATAAGAAATTTGTATATATAAGAAAA
AGAATTCAAATGAGGATGAG

Downstream 100 bases:

>100_bases
AAGATCATTAAAAGAATATATAAGTGAATATAAGTTTGCATTATGGGAGCTTACAAAACGTGAGCTTAAACGTAAATACG
CCAGAAGCTATATGGGAATA

Product: putative ABC-type polysaccharide/polyol phosphate export system, ATP-binding protein

Products: ADP; phosphate; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MRKIVLNKIVYAVAVMCMVITILYCPTDVYAATGSVTFGSESYEARDNSQFQVGVYLKTKSKMGSYHVEVEYDKSRMEYT
GGAESESNGVITLEGIGVSDQIKYMLSFKTISGGDAYIKVKNAYIYTSDANSTEQFDMTELDEAGITIEGEDTGTPRTEE
PTEYVGPFETDIPHLEPSIKLNDTDYYVVDSNQYVPESVSWKYVLVPGKLGNMDVTFYSNEAQDIFFLSLVDSNGETHLY
SYSNSQKQLYECNFYNTGNTIYYYTSPYASDSWPEGLTEDVIKKQNICYALRSDGESGFYKVEADKLTLWNVDENIADAK
PMTGKLIFIMIIAIITGLALIVLVYFWGREVGRARRKKKNSKKKRVIVSNDIKQIKNDDVEKTENHLNEKGEEPIISVQD
VTMKFKISNSSASGMKDFLIQKLKHQINYRELYALDHVSFDVYKGEVVGIIGTNGSGKSTMLRIVSGALNPSGGKVVVDR
RKVQLLTLGTGFDMELTARENIYLNGAIIGYSKKFIDEHFDEIIDFAELQDFVDEKVKNFSSGMVSRLGFAIATAGDAAE
ILILDEVLSVGDEFFRKKSLARVKEMIHGGSTVLMVSHGMGTILDNCSKVVWIEKGKLQMVGDPKTVCAAYRKQQNV

Sequences:

>Translated_637_residues
MRKIVLNKIVYAVAVMCMVITILYCPTDVYAATGSVTFGSESYEARDNSQFQVGVYLKTKSKMGSYHVEVEYDKSRMEYT
GGAESESNGVITLEGIGVSDQIKYMLSFKTISGGDAYIKVKNAYIYTSDANSTEQFDMTELDEAGITIEGEDTGTPRTEE
PTEYVGPFETDIPHLEPSIKLNDTDYYVVDSNQYVPESVSWKYVLVPGKLGNMDVTFYSNEAQDIFFLSLVDSNGETHLY
SYSNSQKQLYECNFYNTGNTIYYYTSPYASDSWPEGLTEDVIKKQNICYALRSDGESGFYKVEADKLTLWNVDENIADAK
PMTGKLIFIMIIAIITGLALIVLVYFWGREVGRARRKKKNSKKKRVIVSNDIKQIKNDDVEKTENHLNEKGEEPIISVQD
VTMKFKISNSSASGMKDFLIQKLKHQINYRELYALDHVSFDVYKGEVVGIIGTNGSGKSTMLRIVSGALNPSGGKVVVDR
RKVQLLTLGTGFDMELTARENIYLNGAIIGYSKKFIDEHFDEIIDFAELQDFVDEKVKNFSSGMVSRLGFAIATAGDAAE
ILILDEVLSVGDEFFRKKSLARVKEMIHGGSTVLMVSHGMGTILDNCSKVVWIEKGKLQMVGDPKTVCAAYRKQQNV
>Mature_637_residues
MRKIVLNKIVYAVAVMCMVITILYCPTDVYAATGSVTFGSESYEARDNSQFQVGVYLKTKSKMGSYHVEVEYDKSRMEYT
GGAESESNGVITLEGIGVSDQIKYMLSFKTISGGDAYIKVKNAYIYTSDANSTEQFDMTELDEAGITIEGEDTGTPRTEE
PTEYVGPFETDIPHLEPSIKLNDTDYYVVDSNQYVPESVSWKYVLVPGKLGNMDVTFYSNEAQDIFFLSLVDSNGETHLY
SYSNSQKQLYECNFYNTGNTIYYYTSPYASDSWPEGLTEDVIKKQNICYALRSDGESGFYKVEADKLTLWNVDENIADAK
PMTGKLIFIMIIAIITGLALIVLVYFWGREVGRARRKKKNSKKKRVIVSNDIKQIKNDDVEKTENHLNEKGEEPIISVQD
VTMKFKISNSSASGMKDFLIQKLKHQINYRELYALDHVSFDVYKGEVVGIIGTNGSGKSTMLRIVSGALNPSGGKVVVDR
RKVQLLTLGTGFDMELTARENIYLNGAIIGYSKKFIDEHFDEIIDFAELQDFVDEKVKNFSSGMVSRLGFAIATAGDAAE
ILILDEVLSVGDEFFRKKSLARVKEMIHGGSTVLMVSHGMGTILDNCSKVVWIEKGKLQMVGDPKTVCAAYRKQQNV

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI30795238, Length=210, Percent_Identity=24.2857142857143, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI27881501, Length=227, Percent_Identity=24.2290748898678, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI31657092, Length=214, Percent_Identity=24.2990654205607, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI6005701, Length=258, Percent_Identity=24.8062015503876, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI27436953, Length=203, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI105990541, Length=202, Percent_Identity=26.7326732673267, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI153792144, Length=204, Percent_Identity=28.921568627451, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI47078218, Length=204, Percent_Identity=28.4313725490196, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI45446740, Length=204, Percent_Identity=28.4313725490196, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI27477115, Length=165, Percent_Identity=29.6969696969697, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI116734710, Length=208, Percent_Identity=24.5192307692308, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI27262624, Length=221, Percent_Identity=25.7918552036199, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI27262626, Length=221, Percent_Identity=25.7918552036199, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI150417984, Length=206, Percent_Identity=27.6699029126214, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI21536376, Length=202, Percent_Identity=24.7524752475248, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87081791, Length=206, Percent_Identity=25.2427184466019, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI87081782, Length=212, Percent_Identity=25.4716981132075, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI48994943, Length=210, Percent_Identity=25.7142857142857, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1786398, Length=233, Percent_Identity=27.4678111587983, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790467, Length=200, Percent_Identity=23.5, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1787029, Length=208, Percent_Identity=26.4423076923077, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081709, Length=210, Percent_Identity=23.3333333333333, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788450, Length=210, Percent_Identity=24.7619047619048, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1788210, Length=212, Percent_Identity=28.7735849056604, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1789032, Length=207, Percent_Identity=23.1884057971014, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI115533608, Length=322, Percent_Identity=23.6024844720497, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17510237, Length=211, Percent_Identity=24.6445497630332, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI116007184, Length=198, Percent_Identity=27.7777777777778, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221500365, Length=198, Percent_Identity=27.7777777777778, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221512771, Length=215, Percent_Identity=24.6511627906977, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666092, Length=205, Percent_Identity=24.390243902439, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71261; Mature: 71261

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIVLNKIVYAVAVMCMVITILYCPTDVYAATGSVTFGSESYEARDNSQFQVGVYLKTK
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCEEECCCCCCCCCCCEEEEEEEEEEC
SKMGSYHVEVEYDKSRMEYTGGAESESNGVITLEGIGVSDQIKYMLSFKTISGGDAYIKV
CCCCCEEEEEEECCCCEEECCCCCCCCCCEEEEEECCCCHHEEEEEEEEEECCCCEEEEE
KNAYIYTSDANSTEQFDMTELDEAGITIEGEDTGTPRTEEPTEYVGPFETDIPHLEPSIK
EEEEEEECCCCCCCCCCCHHHCCCCCEEECCCCCCCCCCCCHHHCCCCCCCCCCCCCCEE
LNDTDYYVVDSNQYVPESVSWKYVLVPGKLGNMDVTFYSNEAQDIFFLSLVDSNGETHLY
ECCCEEEEECCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEE
SYSNSQKQLYECNFYNTGNTIYYYTSPYASDSWPEGLTEDVIKKQNICYALRSDGESGFY
EECCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHCCEEEEEECCCCCCEE
KVEADKLTLWNVDENIADAKPMTGKLIFIMIIAIITGLALIVLVYFWGREVGRARRKKKN
EEEECEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKKKRVIVSNDIKQIKNDDVEKTENHLNEKGEEPIISVQDVTMKFKISNSSASGMKDFLI
CCCCEEEEECCHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCCCHHHHHH
QKLKHQINYRELYALDHVSFDVYKGEVVGIIGTNGSGKSTMLRIVSGALNPSGGKVVVDR
HHHHHHCCHHHEEEEECCEEEEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEC
RKVQLLTLGTGFDMELTARENIYLNGAIIGYSKKFIDEHFDEIIDFAELQDFVDEKVKNF
CEEEEEEECCCCCEEEEECCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSGMVSRLGFAIATAGDAAEILILDEVLSVGDEFFRKKSLARVKEMIHGGSTVLMVSHGM
HHHHHHHHCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GTILDNCSKVVWIEKGKLQMVGDPKTVCAAYRKQQNV
HHHHHCCCEEEEEECCCEEEECCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRKIVLNKIVYAVAVMCMVITILYCPTDVYAATGSVTFGSESYEARDNSQFQVGVYLKTK
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCEEECCCCCCCCCCCEEEEEEEEEEC
SKMGSYHVEVEYDKSRMEYTGGAESESNGVITLEGIGVSDQIKYMLSFKTISGGDAYIKV
CCCCCEEEEEEECCCCEEECCCCCCCCCCEEEEEECCCCHHEEEEEEEEEECCCCEEEEE
KNAYIYTSDANSTEQFDMTELDEAGITIEGEDTGTPRTEEPTEYVGPFETDIPHLEPSIK
EEEEEEECCCCCCCCCCCHHHCCCCCEEECCCCCCCCCCCCHHHCCCCCCCCCCCCCCEE
LNDTDYYVVDSNQYVPESVSWKYVLVPGKLGNMDVTFYSNEAQDIFFLSLVDSNGETHLY
ECCCEEEEECCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEE
SYSNSQKQLYECNFYNTGNTIYYYTSPYASDSWPEGLTEDVIKKQNICYALRSDGESGFY
EECCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHCCEEEEEECCCCCCEE
KVEADKLTLWNVDENIADAKPMTGKLIFIMIIAIITGLALIVLVYFWGREVGRARRKKKN
EEEECEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKKKRVIVSNDIKQIKNDDVEKTENHLNEKGEEPIISVQDVTMKFKISNSSASGMKDFLI
CCCCEEEEECCHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCCCHHHHHH
QKLKHQINYRELYALDHVSFDVYKGEVVGIIGTNGSGKSTMLRIVSGALNPSGGKVVVDR
HHHHHHCCHHHEEEEECCEEEEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEC
RKVQLLTLGTGFDMELTARENIYLNGAIIGYSKKFIDEHFDEIIDFAELQDFVDEKVKNF
CEEEEEEECCCCCEEEEECCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSGMVSRLGFAIATAGDAAEILILDEVLSVGDEFFRKKSLARVKEMIHGGSTVLMVSHGM
HHHHHHHHCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GTILDNCSKVVWIEKGKLQMVGDPKTVCAAYRKQQNV
HHHHHCCCEEEEEECCCEEEECCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; putrescine [Periplasm]; H2O [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]