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The map label for this gene is toxA [H]

Identifier: 238924984

GI number: 238924984

Start: 2515022

End: 2516344

Strand: Reverse

Name: toxA [H]

Synonym: EUBREC_2635

Alternate gene names: 238924984

Gene position: 2516344-2515022 (Counterclockwise)

Preceding gene: 238924985

Following gene: 238924982

Centisome position: 72.94

GC content: 33.86

Gene sequence:

>1323_bases
ATGGAAAATATGAGAAAAATAATCAAATGGGCATTATGTATATGCTTGTGTATATGTTTTGTATGCATAGGGCATAATTG
TGTATATGCTGAAAATGAGGTTGAAGCAGGGGAAAAGCAAATTGTATATAAATGGCTTCGCTGGGAGGATAACTATTATT
ATTATTATGTAGATGAGAATAATAATAATAATTATATTGTAGGATGGAAGTGTATCGATGGGCATTGGTATTATTTTGAT
ACTGATGGTAAGATGATATCTGGTTGGCGGCTAATTAATGGAAAAACATATTATTTTGGAACTGCTTCTGATGGAAAAAT
GAGACATGGCTGGCAAAAAATAAATGATACATGGTATTTTTTTGGTGGAACAGAAGATGGCAAAATGGCTACAGGATGGA
ATAATGTAGGAGGAAGCTGGTATTATTTTTCAAAAGACGGATCAATGAAATATGGTTGGCAGAAGATAAATGGGCGATGG
TACTTCTTGGGGGATAAAAATGATGGCGTTATGAAAAGTGGTTGGTTAAAGAATAATACTAAATGGTACTATTTGTCATC
GTGGAATGATGGTGCTATGAAATGTGGCTGGCAAAGAATCGGGGCGACATGGTATTTGTTTGCAACAGATGGACATATGC
TATCTGGCTGGCAGAAAATAAATAATTCTTGGTACTATTTAGGCGGTAATAATGATGGTGCTATGAAATATGGTTGGAAA
TATATAAATTCAAACTGGTATTATTTCGGTGGTGTCAATGATGGAATTATGAAGTCAGGATGGCAATATATAGGCAATAA
GTGGTATTATTTTTATAGGGAGAATGATTCCAAAGGTGGTACACATGGTGCTATGGCATCTAATAGAAATATAGATGGAT
ATTATGTATCAAAAAATGGTGATTGGATTGATCCAAGTTGGCTTAATAGTTGCGCGCAAGGGTATTCAAGTTCCACAAAA
TACTTGATTTTAGTGGATCGATCTTCTTGTATGGTGGGAATATATCAAGGAAGTAAAAATAATTGGAAATTAAAATATTT
CTGGCCTTGTGCTCCTGGAAAGGCATCTACACCTACTATATCAGGAGAGTATAATGTAGCTGGTAAAGGATACTATTTTG
ATTCAGGAAATTCTAGATGTTTTTATTATACGCAGTTTAAAGGCAACTATTTATTCCATAGCGTTTTATATAATAAAAAT
GGCACGCTTCAAGATGGACGTGTAGGTATACAATTATCTCATGGATGTGTAAGATTAGAGATTAATAATGCGAAGTGGAT
ATATGATAATATTCCTAGGGGAACACATGTAGTTATTTATTAA

Upstream 100 bases:

>100_bases
ACAGGTTGGCAAAAAATTGGAAATAAAATGTATTATATGAATTCTAGCGGAGTTTGGCTATATTAGCGGATTTGAAATGT
AATATTAAAACGAATAGGAG

Downstream 100 bases:

>100_bases
TTTATAAAGTTATAGTAAAAACAGACAGGTTATGGCTACCTGTCTGTTTGAGTATTGTGCGCCTAGCGGCGCACGTTTCT
AACGGGTTAAAGTCCCGAAT

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MENMRKIIKWALCICLCICFVCIGHNCVYAENEVEAGEKQIVYKWLRWEDNYYYYYVDENNNNNYIVGWKCIDGHWYYFD
TDGKMISGWRLINGKTYYFGTASDGKMRHGWQKINDTWYFFGGTEDGKMATGWNNVGGSWYYFSKDGSMKYGWQKINGRW
YFLGDKNDGVMKSGWLKNNTKWYYLSSWNDGAMKCGWQRIGATWYLFATDGHMLSGWQKINNSWYYLGGNNDGAMKYGWK
YINSNWYYFGGVNDGIMKSGWQYIGNKWYYFYRENDSKGGTHGAMASNRNIDGYYVSKNGDWIDPSWLNSCAQGYSSSTK
YLILVDRSSCMVGIYQGSKNNWKLKYFWPCAPGKASTPTISGEYNVAGKGYYFDSGNSRCFYYTQFKGNYLFHSVLYNKN
GTLQDGRVGIQLSHGCVRLEINNAKWIYDNIPRGTHVVIY

Sequences:

>Translated_440_residues
MENMRKIIKWALCICLCICFVCIGHNCVYAENEVEAGEKQIVYKWLRWEDNYYYYYVDENNNNNYIVGWKCIDGHWYYFD
TDGKMISGWRLINGKTYYFGTASDGKMRHGWQKINDTWYFFGGTEDGKMATGWNNVGGSWYYFSKDGSMKYGWQKINGRW
YFLGDKNDGVMKSGWLKNNTKWYYLSSWNDGAMKCGWQRIGATWYLFATDGHMLSGWQKINNSWYYLGGNNDGAMKYGWK
YINSNWYYFGGVNDGIMKSGWQYIGNKWYYFYRENDSKGGTHGAMASNRNIDGYYVSKNGDWIDPSWLNSCAQGYSSSTK
YLILVDRSSCMVGIYQGSKNNWKLKYFWPCAPGKASTPTISGEYNVAGKGYYFDSGNSRCFYYTQFKGNYLFHSVLYNKN
GTLQDGRVGIQLSHGCVRLEINNAKWIYDNIPRGTHVVIY
>Mature_440_residues
MENMRKIIKWALCICLCICFVCIGHNCVYAENEVEAGEKQIVYKWLRWEDNYYYYYVDENNNNNYIVGWKCIDGHWYYFD
TDGKMISGWRLINGKTYYFGTASDGKMRHGWQKINDTWYFFGGTEDGKMATGWNNVGGSWYYFSKDGSMKYGWQKINGRW
YFLGDKNDGVMKSGWLKNNTKWYYLSSWNDGAMKCGWQRIGATWYLFATDGHMLSGWQKINNSWYYLGGNNDGAMKYGWK
YINSNWYYFGGVNDGIMKSGWQYIGNKWYYFYRENDSKGGTHGAMASNRNIDGYYVSKNGDWIDPSWLNSCAQGYSSSTK
YLILVDRSSCMVGIYQGSKNNWKLKYFWPCAPGKASTPTISGEYNVAGKGYYFDSGNSRCFYYTQFKGNYLFHSVLYNKN
GTLQDGRVGIQLSHGCVRLEINNAKWIYDNIPRGTHVVIY

Specific function: Only after the enteral delivery of the enterotoxin A may the characteristic disease called pseudomembranous colitis be induced [H]

COG id: COG5263

COG function: function code R; FOG: Glucan-binding domain (YG repeat)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 32 cell wall-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018337
- InterPro:   IPR007577
- InterPro:   IPR020974 [H]

Pfam domain/function: PF01473 CW_binding_1; PF04488 Gly_transf_sug; PF11713 Peptidase_C80 [H]

EC number: NA

Molecular weight: Translated: 51363; Mature: 51363

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENMRKIIKWALCICLCICFVCIGHNCVYAENEVEAGEKQIVYKWLRWEDNYYYYYVDEN
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEEEEECCEEEEEEECC
NNNNYIVGWKCIDGHWYYFDTDGKMISGWRLINGKTYYFGTASDGKMRHGWQKINDTWYF
CCCCEEEEEEEECCEEEEEECCCCEEEEEEEECCEEEEEEECCCCCHHCCCEECCCEEEE
FGGTEDGKMATGWNNVGGSWYYFSKDGSMKYGWQKINGRWYFLGDKNDGVMKSGWLKNNT
EECCCCCCEECCCCCCCCEEEEECCCCCEEECEEEECCEEEEEECCCCCCEECCEEECCC
KWYYLSSWNDGAMKCGWQRIGATWYLFATDGHMLSGWQKINNSWYYLGGNNDGAMKYGWK
EEEEEEECCCCCCCCCCEECCEEEEEEEECCCEECCHHHHCCCEEEEECCCCCCEEEEEE
YINSNWYYFGGVNDGIMKSGWQYIGNKWYYFYRENDSKGGTHGAMASNRNIDGYYVSKNG
EECCCEEEECCCCCCHHHCCHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCC
DWIDPSWLNSCAQGYSSSTKYLILVDRSSCMVGIYQGSKNNWKLKYFWPCAPGKASTPTI
CCCCHHHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCCCEEEEEEEECCCCCCCCCEE
SGEYNVAGKGYYFDSGNSRCFYYTQFKGNYLFHSVLYNKNGTLQDGRVGIQLSHGCVRLE
CCEEEECCCEEEEECCCCEEEEEEEECCCEEEEEEEECCCCCEECCEEEEEEECCEEEEE
INNAKWIYDNIPRGTHVVIY
ECCCEEEEECCCCCCEEEEC
>Mature Secondary Structure
MENMRKIIKWALCICLCICFVCIGHNCVYAENEVEAGEKQIVYKWLRWEDNYYYYYVDEN
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEEEEECCEEEEEEECC
NNNNYIVGWKCIDGHWYYFDTDGKMISGWRLINGKTYYFGTASDGKMRHGWQKINDTWYF
CCCCEEEEEEEECCEEEEEECCCCEEEEEEEECCEEEEEEECCCCCHHCCCEECCCEEEE
FGGTEDGKMATGWNNVGGSWYYFSKDGSMKYGWQKINGRWYFLGDKNDGVMKSGWLKNNT
EECCCCCCEECCCCCCCCEEEEECCCCCEEECEEEECCEEEEEECCCCCCEECCEEECCC
KWYYLSSWNDGAMKCGWQRIGATWYLFATDGHMLSGWQKINNSWYYLGGNNDGAMKYGWK
EEEEEEECCCCCCCCCCEECCEEEEEEEECCCEECCHHHHCCCEEEEECCCCCCEEEEEE
YINSNWYYFGGVNDGIMKSGWQYIGNKWYYFYRENDSKGGTHGAMASNRNIDGYYVSKNG
EECCCEEEECCCCCCHHHCCHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCC
DWIDPSWLNSCAQGYSSSTKYLILVDRSSCMVGIYQGSKNNWKLKYFWPCAPGKASTPTI
CCCCHHHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCCCEEEEEEEECCCCCCCCCEE
SGEYNVAGKGYYFDSGNSRCFYYTQFKGNYLFHSVLYNKNGTLQDGRVGIQLSHGCVRLE
CCEEEECCCEEEEECCCCEEEEEEEECCCEEEEEEEECCCCCEECCEEEEEEECCEEEEE
INNAKWIYDNIPRGTHVVIY
ECCCEEEEECCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2109310; 2105276 [H]