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The map label for this gene is licC [H]

Identifier: 238924957

GI number: 238924957

Start: 2484434

End: 2485168

Strand: Reverse

Name: licC [H]

Synonym: EUBREC_2608

Alternate gene names: 238924957

Gene position: 2485168-2484434 (Counterclockwise)

Preceding gene: 238924958

Following gene: 238924955

Centisome position: 72.04

GC content: 38.37

Gene sequence:

>735_bases
ATGCATGAAGTAAAACGCGCGATTATCATGGCAGCAGGACTTGGTAATCGTATGAGACCGGTAACGCTTACTACTCCGAA
GCCATTGGTAAGGGTGAATGGAAAGCGTATGATAGATACAGTTATTGAAGGCTTACACGGTAATGGAATCACGGAGATTT
ATATTGTTGCCGGATATTTAAAGGAACAGTTTTATGAATTAGAGAATGAATATCCGGGAGTTACTATAATTGAAAATCCT
TATTATGAAAGCTGTAATAATATTTCATCACTATATGTTGCAAGAGATCATATTGAGGATGCAATTATTCTTGATGGCGA
CCAGATTATATATAATCCTGAAATTCTATCAAAAGAATTCGAACGCTCGGGTTATAACAGTGTATGGACTGATGATGAAA
CAGATGAGTGGCTTCAGACAGTAGAAGATGGAATTGTAACATCCTGCAGCAGGAGTGGCGGAAGTCATGGATGGCAGCTT
TATAGCATCTCCAGATGGACTGCGGCAGATGGGCGCAAACTGAAAAAACATCTTGAAATGGAATTTGAGAACAAAAAAAA
TACTCAGATATACTGGGATGACGTTGCAATGTTCTGCTATCCGGATGAATATCAGCTTGGCATATATGAGATGCAAAAAG
GCGATATTATTGAGATTGATAATTTGCAGGAGCTTGCTGAGATAGATAGCAGCTATAAGAAATATATGGAGCAATCTGGT
GATATGTCAAGATGA

Upstream 100 bases:

>100_bases
GTGTTGATTTTGGTGAATATTCACTCAGACAGTACAGATATGCAAAGGATTATTACAAAGTAGTACAGGATGAAATGCAG
AAATTGGAGGATAATTAAAA

Downstream 100 bases:

>100_bases
TTTTTGAAAAGATTTCGATATGTTTTTCAGAAAAAGGGTAACTTTAATAGACCTATGCAAAAACACAGGCTAAAACCAGT
TATTCATTTGATGTATCCAG

Product: choline kinase

Products: ADP; O-phosphocholine

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MHEVKRAIIMAAGLGNRMRPVTLTTPKPLVRVNGKRMIDTVIEGLHGNGITEIYIVAGYLKEQFYELENEYPGVTIIENP
YYESCNNISSLYVARDHIEDAIILDGDQIIYNPEILSKEFERSGYNSVWTDDETDEWLQTVEDGIVTSCSRSGGSHGWQL
YSISRWTAADGRKLKKHLEMEFENKKNTQIYWDDVAMFCYPDEYQLGIYEMQKGDIIEIDNLQELAEIDSSYKKYMEQSG
DMSR

Sequences:

>Translated_244_residues
MHEVKRAIIMAAGLGNRMRPVTLTTPKPLVRVNGKRMIDTVIEGLHGNGITEIYIVAGYLKEQFYELENEYPGVTIIENP
YYESCNNISSLYVARDHIEDAIILDGDQIIYNPEILSKEFERSGYNSVWTDDETDEWLQTVEDGIVTSCSRSGGSHGWQL
YSISRWTAADGRKLKKHLEMEFENKKNTQIYWDDVAMFCYPDEYQLGIYEMQKGDIIEIDNLQELAEIDSSYKKYMEQSG
DMSR
>Mature_244_residues
MHEVKRAIIMAAGLGNRMRPVTLTTPKPLVRVNGKRMIDTVIEGLHGNGITEIYIVAGYLKEQFYELENEYPGVTIIENP
YYESCNNISSLYVARDHIEDAIILDGDQIIYNPEILSKEFERSGYNSVWTDDETDEWLQTVEDGIVTSCSRSGGSHGWQL
YSISRWTAADGRKLKKHLEMEFENKKNTQIYWDDVAMFCYPDEYQLGIYEMQKGDIIEIDNLQELAEIDSSYKKYMEQSG
DMSR

Specific function: May Play A Role In Stationary Phase Survival. [C]

COG id: COG4750

COG function: function code M; CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017189
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: 2.7.1.32; 2.7.7.15

Molecular weight: Translated: 28156; Mature: 28156

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEVKRAIIMAAGLGNRMRPVTLTTPKPLVRVNGKRMIDTVIEGLHGNGITEIYIVAGYL
CCHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCHHHHHHHHHCCCCCCCEEEEEEHHHH
KEQFYELENEYPGVTIIENPYYESCNNISSLYVARDHIEDAIILDGDQIIYNPEILSKEF
HHHHHHHHCCCCCEEEEECCCHHHHCCHHHHEEEHHCCCCEEEECCCEEEECHHHHHHHH
ERSGYNSVWTDDETDEWLQTVEDGIVTSCSRSGGSHGWQLYSISRWTAADGRKLKKHLEM
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
EFENKKNTQIYWDDVAMFCYPDEYQLGIYEMQKGDIIEIDNLQELAEIDSSYKKYMEQSG
HCCCCCCCEEEEECEEEEEECCCCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHCC
DMSR
CCCC
>Mature Secondary Structure
MHEVKRAIIMAAGLGNRMRPVTLTTPKPLVRVNGKRMIDTVIEGLHGNGITEIYIVAGYL
CCHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCHHHHHHHHHCCCCCCCEEEEEEHHHH
KEQFYELENEYPGVTIIENPYYESCNNISSLYVARDHIEDAIILDGDQIIYNPEILSKEF
HHHHHHHHCCCCCEEEEECCCHHHHCCHHHHEEEHHCCCCEEEECCCEEEECHHHHHHHH
ERSGYNSVWTDDETDEWLQTVEDGIVTSCSRSGGSHGWQLYSISRWTAADGRKLKKHLEM
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
EFENKKNTQIYWDDVAMFCYPDEYQLGIYEMQKGDIIEIDNLQELAEIDSSYKKYMEQSG
HCCCCCCCEEEEECEEEEEECCCCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHCC
DMSR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; choline

Specific reaction: ATP + choline = ADP + O-phosphocholine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2479481; 7542800 [H]