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The map label for this gene is recG [H]

Identifier: 238924032

GI number: 238924032

Start: 1553060

End: 1555126

Strand: Direct

Name: recG [H]

Synonym: EUBREC_1670

Alternate gene names: 238924032

Gene position: 1553060-1555126 (Clockwise)

Preceding gene: 238924031

Following gene: 238924034

Centisome position: 45.02

GC content: 45.09

Gene sequence:

>2067_bases
ATGGATATAGCTTCACCGATTACCGCGGTTAAGGGAATCGGGGAAAAAACACAAAAAGCATTTGCTAAAATGGGAGTATA
CACCGTTGGTGATATACTCCTTCATTTTCCCCGGGATTATGTAAAGTTTCCGGAAATAACGGATATTGATGAACTGAATA
ATGTAAACGTAAGCAGCACCTATGCCATCTATGCTGTGATTAAAAAGGCACCTGTAGTGAAAAATACAGCGAGAATGCAG
ATTACATTGCAGGATATCGGCTCGCCCGGGCATATGATACAGCTGGTATGGTACCGTATGCCATACCTTAAGGCACAGCT
TGTGCAGGGGAGACATCTTATATTTTACGGACATATTAAGCCAAAGGGAGGCCGATATGTCATGGAGCAGCCTGTGGTGT
ATGAGGTGCAAAAGTACGAGGCTATACGCGATACACTGCAGCCTGTGTACTCCGTGACAAGCGGTGTGACAAACAATCTG
ATAGTGAAGACGATAAAGGAGACTCTGTCACATGATACACTGCTGTCAGATTACCTGCCTAAGGATATAAGGCACAGATA
CGGCTTTTGCGAGTACAATTATGCCATGAAGCAGATACATTTCCCTGATGACTTTGACGCTCTTGTGGAGGCAAGAAGAC
GGCTTGTTTTTGATGAGTTTTTTCTCTTTATCATGGGCATGCGGTATCAGAATAAAAAGCAGCAGAAGGACAAAAATGAG
TTTGAGTTTACGGATGATGCTTTTATAGACGGACTGATTGATAAGCTTCCGTATGAGCTGACAGGCGCGCAGAAGAAGAC
AATAGATGAGATAAAGCAGGATATTAAAAGCCCTTATGTGATGCAGAGGCTTATTCAGGGTGACGTGGGCTCAGGAAAGA
CGATTGTTGCTTTTCTTCTTATGGCGTGGGCGTCAAAATGTGGCTATCAGTCTGCTATTATGGCTCCGACGGAGGTCCTT
GCAAACCAGCATTACGAGACGTTTTGCTCACTGGTCAGTCAGTTTGGACTTGACAGTCCTGTTGTGCTTCTTACCGGTTC
CATGACGGCAAAGCAGAAAAGAGAAGCCTATGCGAGCCTTGAAAACGAGAAAAATGCGCTTATTATAGGCACTCATGCGC
TCATACAGGAGAAAGCTGATTTTTCCAATCTGTCGCTTGTTATCACAGATGAGCAGCACAGATTTGGAGTGAAGCAGAGG
GAGAGCTTCTCGGATAAGGGAAGAAAGCCACATATACTTGTGATGAGTGCCACTCCGATACCGCGTACGTTAGCAATAAT
CATATACGGTGATATGGATATCTCTGTCATAAATGAGGTGCCGGCAAAGAGGCTTCCTATCAAGAACTGTGTGGTTGGCA
CAGCATTCAGGCCAAAGGCCTACAGCTTCATCGAGGAGCAGGTGAGAGCCGGCCATCAGGCGTATGTTATATGCCCTCTT
GTGGAGGAAACCGAAAACTCGGAAGGGGAAAATGTCACAGACTATGCAGATGTGCTTAAAGCGGCACTGCCAAAGGATAT
CACTGTAGATGTGCTTAACGGCAGGATGAAGAGCAAGGCAAAGGATGAGGTGATGCAGCGCTTTGCAAATAATGAGTCGC
AGGTGCTTGTGTCCACAACAGTCGTGGAGGTTGGGGTAAATGTGCCCAATGCAACCGTCATGATGATAGAAAATGCAGAC
AGGTTTGGACTTGCACAGCTTCATCAGCTAAGAGGCCGTGTAGGCAGGGGGGATGCACAGTCGTATTGCATTTTCATCAA
TTCGTCAAATTCAAAGAAATCAAAAAAACGTCTGGAGATATTAAATAAATCAAATGATGGCTTTTATATAGCAAGTGAGG
ATTTAAAGCTCAGAGGTCCCGGGGATTTCTTTGGAATCAGGCAGAGTGGAGACCTTGCGTTTGCACTTGCGGATGTGTAT
CAGGACAGCGATGTGCTAAAGGAAGCATCTGAGATGGTGGATGAGGTGCTTGAAGCAGACCCGGCGCTTTGTACACCGGA
AAACAGAATACTGAAAAAGAAAATGGATGAATTTGCAAAAGAACAATTAAAGAGGATGAATCTGTGA

Upstream 100 bases:

>100_bases
AGGTCAACGATGGCGGACAGCCAATCTACTATTATGTTATTTCTGTAGAGTAAAGCCTTTTAAAGAATATAAATGATATT
TATTATATTTAGGAGCAAAT

Downstream 100 bases:

>100_bases
TTAGCTTAAATGGCAAAAATAAAAGCTGATATAGCATGCAGGACTATGCATGTGTATATCAGCTTTTTACTTTAAGCGTT
TTGGAATGGTTATGAAATAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 688; Mature: 688

Protein sequence:

>688_residues
MDIASPITAVKGIGEKTQKAFAKMGVYTVGDILLHFPRDYVKFPEITDIDELNNVNVSSTYAIYAVIKKAPVVKNTARMQ
ITLQDIGSPGHMIQLVWYRMPYLKAQLVQGRHLIFYGHIKPKGGRYVMEQPVVYEVQKYEAIRDTLQPVYSVTSGVTNNL
IVKTIKETLSHDTLLSDYLPKDIRHRYGFCEYNYAMKQIHFPDDFDALVEARRRLVFDEFFLFIMGMRYQNKKQQKDKNE
FEFTDDAFIDGLIDKLPYELTGAQKKTIDEIKQDIKSPYVMQRLIQGDVGSGKTIVAFLLMAWASKCGYQSAIMAPTEVL
ANQHYETFCSLVSQFGLDSPVVLLTGSMTAKQKREAYASLENEKNALIIGTHALIQEKADFSNLSLVITDEQHRFGVKQR
ESFSDKGRKPHILVMSATPIPRTLAIIIYGDMDISVINEVPAKRLPIKNCVVGTAFRPKAYSFIEEQVRAGHQAYVICPL
VEETENSEGENVTDYADVLKAALPKDITVDVLNGRMKSKAKDEVMQRFANNESQVLVSTTVVEVGVNVPNATVMMIENAD
RFGLAQLHQLRGRVGRGDAQSYCIFINSSNSKKSKKRLEILNKSNDGFYIASEDLKLRGPGDFFGIRQSGDLAFALADVY
QDSDVLKEASEMVDEVLEADPALCTPENRILKKKMDEFAKEQLKRMNL

Sequences:

>Translated_688_residues
MDIASPITAVKGIGEKTQKAFAKMGVYTVGDILLHFPRDYVKFPEITDIDELNNVNVSSTYAIYAVIKKAPVVKNTARMQ
ITLQDIGSPGHMIQLVWYRMPYLKAQLVQGRHLIFYGHIKPKGGRYVMEQPVVYEVQKYEAIRDTLQPVYSVTSGVTNNL
IVKTIKETLSHDTLLSDYLPKDIRHRYGFCEYNYAMKQIHFPDDFDALVEARRRLVFDEFFLFIMGMRYQNKKQQKDKNE
FEFTDDAFIDGLIDKLPYELTGAQKKTIDEIKQDIKSPYVMQRLIQGDVGSGKTIVAFLLMAWASKCGYQSAIMAPTEVL
ANQHYETFCSLVSQFGLDSPVVLLTGSMTAKQKREAYASLENEKNALIIGTHALIQEKADFSNLSLVITDEQHRFGVKQR
ESFSDKGRKPHILVMSATPIPRTLAIIIYGDMDISVINEVPAKRLPIKNCVVGTAFRPKAYSFIEEQVRAGHQAYVICPL
VEETENSEGENVTDYADVLKAALPKDITVDVLNGRMKSKAKDEVMQRFANNESQVLVSTTVVEVGVNVPNATVMMIENAD
RFGLAQLHQLRGRVGRGDAQSYCIFINSSNSKKSKKRLEILNKSNDGFYIASEDLKLRGPGDFFGIRQSGDLAFALADVY
QDSDVLKEASEMVDEVLEADPALCTPENRILKKKMDEFAKEQLKRMNL
>Mature_688_residues
MDIASPITAVKGIGEKTQKAFAKMGVYTVGDILLHFPRDYVKFPEITDIDELNNVNVSSTYAIYAVIKKAPVVKNTARMQ
ITLQDIGSPGHMIQLVWYRMPYLKAQLVQGRHLIFYGHIKPKGGRYVMEQPVVYEVQKYEAIRDTLQPVYSVTSGVTNNL
IVKTIKETLSHDTLLSDYLPKDIRHRYGFCEYNYAMKQIHFPDDFDALVEARRRLVFDEFFLFIMGMRYQNKKQQKDKNE
FEFTDDAFIDGLIDKLPYELTGAQKKTIDEIKQDIKSPYVMQRLIQGDVGSGKTIVAFLLMAWASKCGYQSAIMAPTEVL
ANQHYETFCSLVSQFGLDSPVVLLTGSMTAKQKREAYASLENEKNALIIGTHALIQEKADFSNLSLVITDEQHRFGVKQR
ESFSDKGRKPHILVMSATPIPRTLAIIIYGDMDISVINEVPAKRLPIKNCVVGTAFRPKAYSFIEEQVRAGHQAYVICPL
VEETENSEGENVTDYADVLKAALPKDITVDVLNGRMKSKAKDEVMQRFANNESQVLVSTTVVEVGVNVPNATVMMIENAD
RFGLAQLHQLRGRVGRGDAQSYCIFINSSNSKKSKKRLEILNKSNDGFYIASEDLKLRGPGDFFGIRQSGDLAFALADVY
QDSDVLKEASEMVDEVLEADPALCTPENRILKKKMDEFAKEQLKRMNL

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=681, Percent_Identity=36.1233480176211, Blast_Score=396, Evalue=1e-111,
Organism=Escherichia coli, GI1787357, Length=406, Percent_Identity=34.4827586206897, Blast_Score=233, Evalue=4e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77633; Mature: 77633

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIASPITAVKGIGEKTQKAFAKMGVYTVGDILLHFPRDYVKFPEITDIDELNNVNVSST
CCCCHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHCCCCCCCCHHCCCCCCCHH
YAIYAVIKKAPVVKNTARMQITLQDIGSPGHMIQLVWYRMPYLKAQLVQGRHLIFYGHIK
HHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHCCCEEEEEEEEC
PKGGRYVMEQPVVYEVQKYEAIRDTLQPVYSVTSGVTNNLIVKTIKETLSHDTLLSDYLP
CCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
KDIRHRYGFCEYNYAMKQIHFPDDFDALVEARRRLVFDEFFLFIMGMRYQNKKQQKDKNE
HHHHHHCCCEEECHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCC
FEFTDDAFIDGLIDKLPYELTGAQKKTIDEIKQDIKSPYVMQRLIQGDVGSGKTIVAFLL
CCCCHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHH
MAWASKCGYQSAIMAPTEVLANQHYETFCSLVSQFGLDSPVVLLTGSMTAKQKREAYASL
HHHHHHCCCCCHHCCHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHH
ENEKNALIIGTHALIQEKADFSNLSLVITDEQHRFGVKQRESFSDKGRKPHILVMSATPI
CCCCCEEEEEHHHHHHHCCCCCCEEEEEECCHHHCCCHHHHHHHHCCCCCEEEEEECCCC
PRTLAIIIYGDMDISVINEVPAKRLPIKNCVVGTAFRPKAYSFIEEQVRAGHQAYVICPL
CCEEEEEEECCCCHHHHHHCCHHCCCHHHCEECCCCCCHHHHHHHHHHHCCCCEEEEEEE
VEETENSEGENVTDYADVLKAALPKDITVDVLNGRMKSKAKDEVMQRFANNESQVLVSTT
HHCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEE
VVEVGVNVPNATVMMIENADRFGLAQLHQLRGRVGRGDAQSYCIFINSSNSKKSKKRLEI
EEEECCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHH
LNKSNDGFYIASEDLKLRGPGDFFGIRQSGDLAFALADVYQDSDVLKEASEMVDEVLEAD
HCCCCCCEEEEECCEEEECCCCEECCCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHCC
PALCTPENRILKKKMDEFAKEQLKRMNL
CCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIASPITAVKGIGEKTQKAFAKMGVYTVGDILLHFPRDYVKFPEITDIDELNNVNVSST
CCCCHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHCCCCCCCCHHCCCCCCCHH
YAIYAVIKKAPVVKNTARMQITLQDIGSPGHMIQLVWYRMPYLKAQLVQGRHLIFYGHIK
HHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHCCCEEEEEEEEC
PKGGRYVMEQPVVYEVQKYEAIRDTLQPVYSVTSGVTNNLIVKTIKETLSHDTLLSDYLP
CCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
KDIRHRYGFCEYNYAMKQIHFPDDFDALVEARRRLVFDEFFLFIMGMRYQNKKQQKDKNE
HHHHHHCCCEEECHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCC
FEFTDDAFIDGLIDKLPYELTGAQKKTIDEIKQDIKSPYVMQRLIQGDVGSGKTIVAFLL
CCCCHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHH
MAWASKCGYQSAIMAPTEVLANQHYETFCSLVSQFGLDSPVVLLTGSMTAKQKREAYASL
HHHHHHCCCCCHHCCHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHH
ENEKNALIIGTHALIQEKADFSNLSLVITDEQHRFGVKQRESFSDKGRKPHILVMSATPI
CCCCCEEEEEHHHHHHHCCCCCCEEEEEECCHHHCCCHHHHHHHHCCCCCEEEEEECCCC
PRTLAIIIYGDMDISVINEVPAKRLPIKNCVVGTAFRPKAYSFIEEQVRAGHQAYVICPL
CCEEEEEEECCCCHHHHHHCCHHCCCHHHCEECCCCCCHHHHHHHHHHHCCCCEEEEEEE
VEETENSEGENVTDYADVLKAALPKDITVDVLNGRMKSKAKDEVMQRFANNESQVLVSTT
HHCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEE
VVEVGVNVPNATVMMIENADRFGLAQLHQLRGRVGRGDAQSYCIFINSSNSKKSKKRLEI
EEEECCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHH
LNKSNDGFYIASEDLKLRGPGDFFGIRQSGDLAFALADVYQDSDVLKEASEMVDEVLEAD
HCCCCCCEEEEECCEEEECCCCEECCCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHCC
PALCTPENRILKKKMDEFAKEQLKRMNL
CCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]