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The map label for this gene is ftsW [H]

Identifier: 238924022

GI number: 238924022

Start: 1545401

End: 1546858

Strand: Direct

Name: ftsW [H]

Synonym: EUBREC_1660

Alternate gene names: 238924022

Gene position: 1545401-1546858 (Clockwise)

Preceding gene: 238924021

Following gene: 238924023

Centisome position: 44.8

GC content: 41.22

Gene sequence:

>1458_bases
ATGGTACATCTGATAGTACAGCTTTCCAAGTATATTATGATAATACTTTTTCTCATATATACTTTTTTATGCTTTCATTT
ATTCAAGTATCCCGACAAGCCGAAAAAGCAGAAGCATATATATAATCTGCAGAGATTTTATATGTTTCTGATTCATTTAG
ATGGTTTTTTGGTGCTCTTTGTCACGACAATGGATACGAAGATAATAGGATTTTATATAGCACAGCTTGTGCTTTTTGAA
TCAATTTATTTGATTTATCATAAGTTTTATAAGAATGCCTCAGAGCTTGTGCTAAACAACATGGTGATGATGCTTTGTAT
AAGCATGATTATTCTAACGAGAATTTCGTTTGACAAGGCATTAAGGCAGTTTGTTTTTGTACTTGCCGGAACGATATTTG
CGTTTTTAATACCGCTTATCATGCAAAAAGGCACGATGTTTCGAAAACTGACATGGACATATGCCGGTGTGGGAATAGTT
GGACTTTTGTCGGTGCTTGTGGTAGGAGTGGCGAGCAGAGGAGCAAAGCTTTCTTTGACATTTGGTCCTGTTTCGATTCA
GCCGTCAGAGTTTGTAAAGATACTTTTTGTGTTTTTTATAGCATCCATGCTGTATAAATCAACTGATTTAAAGCAGCTTG
CCATAACAAGCGGCGTATCGGCAGTGTTTGTGCTGATACTTGTTGCATCAAACGACCTCGGTGGAGCGCTTTTGTATTTC
TTTACATATCTGGTCATGATTTATGTTGCGACAAAAAGGTTTTATATTTTTGCCGGAGGTCTTGCGTTTGTGGGGCTTGG
AATGTACGCTGGTTATCATCTGTTTTCACATGTGAAAAACAGAATTGTTGCATGGCTTGATCCTCTTTCTGTCATAGACA
AGGCCGGCTATCAGGTGTGTCAGTCGCTCTTTGCCATAGGTACAGGCGGACTGTTTGGCTTTGGACTGGGACAGGGACTG
CCGAATAAGATACCTATTGTGTCAAAAGACTTTATCATAGCGGCTATCTCAGAGGAGATGGGCGGTATATTTGCTGTCTG
CCTCATCATGGTTTGTGTAAGCTGCTTTCTTATGATATTTAATCTTTCCATGCAGATGAAGGATGCGTTTTACAAGTATG
TGGCGCTTGGACTTGGCAGTGTGTATGCGCTTCAGGTGCTTTTAACTGTCGGCGGCTCAACCAAGTTTATACCGATGACC
GGTGTGACGCTGCCGCTTGTGAGCTACGGTGGCAGCTCGCTTCTATCTACGATGATTATTTTTGGAATGATACAGGGCAT
GTATATTATGCAGGCAGCCCCTGAAAAAAGGAGAAATATAGATGACAAGAGACGAAAGGACCATGAGACAAAAAACAGAC
AAAAGCAGACAGCTAAAGAGCCGGGGGCGCAGGGAAGTCAACAGAGAAGGAGAAAACCGGCAGCAGGCAGCAAAAACAGC
ACGAAGACACAGAAATAG

Upstream 100 bases:

>100_bases
TACAGCTTTACAATCGAGACTCCAAAGCAGATTAAGGCGGTTATGGATGATAAGGTAGCTGAATATACAAACGGACATTA
CAAAAGAGGAGTAGAATAAC

Downstream 100 bases:

>100_bases
AGAGTATGCGGTTGTTACATATTTTTTCCTTATAGTTTTTGTTGGATTGATAGGTTATTTCTTATATTTCCAGTTTGTAA
AAAGCGACGAATTCATCAAC

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MVHLIVQLSKYIMIILFLIYTFLCFHLFKYPDKPKKQKHIYNLQRFYMFLIHLDGFLVLFVTTMDTKIIGFYIAQLVLFE
SIYLIYHKFYKNASELVLNNMVMMLCISMIILTRISFDKALRQFVFVLAGTIFAFLIPLIMQKGTMFRKLTWTYAGVGIV
GLLSVLVVGVASRGAKLSLTFGPVSIQPSEFVKILFVFFIASMLYKSTDLKQLAITSGVSAVFVLILVASNDLGGALLYF
FTYLVMIYVATKRFYIFAGGLAFVGLGMYAGYHLFSHVKNRIVAWLDPLSVIDKAGYQVCQSLFAIGTGGLFGFGLGQGL
PNKIPIVSKDFIIAAISEEMGGIFAVCLIMVCVSCFLMIFNLSMQMKDAFYKYVALGLGSVYALQVLLTVGGSTKFIPMT
GVTLPLVSYGGSSLLSTMIIFGMIQGMYIMQAAPEKRRNIDDKRRKDHETKNRQKQTAKEPGAQGSQQRRRKPAAGSKNS
TKTQK

Sequences:

>Translated_485_residues
MVHLIVQLSKYIMIILFLIYTFLCFHLFKYPDKPKKQKHIYNLQRFYMFLIHLDGFLVLFVTTMDTKIIGFYIAQLVLFE
SIYLIYHKFYKNASELVLNNMVMMLCISMIILTRISFDKALRQFVFVLAGTIFAFLIPLIMQKGTMFRKLTWTYAGVGIV
GLLSVLVVGVASRGAKLSLTFGPVSIQPSEFVKILFVFFIASMLYKSTDLKQLAITSGVSAVFVLILVASNDLGGALLYF
FTYLVMIYVATKRFYIFAGGLAFVGLGMYAGYHLFSHVKNRIVAWLDPLSVIDKAGYQVCQSLFAIGTGGLFGFGLGQGL
PNKIPIVSKDFIIAAISEEMGGIFAVCLIMVCVSCFLMIFNLSMQMKDAFYKYVALGLGSVYALQVLLTVGGSTKFIPMT
GVTLPLVSYGGSSLLSTMIIFGMIQGMYIMQAAPEKRRNIDDKRRKDHETKNRQKQTAKEPGAQGSQQRRRKPAAGSKNS
TKTQK
>Mature_485_residues
MVHLIVQLSKYIMIILFLIYTFLCFHLFKYPDKPKKQKHIYNLQRFYMFLIHLDGFLVLFVTTMDTKIIGFYIAQLVLFE
SIYLIYHKFYKNASELVLNNMVMMLCISMIILTRISFDKALRQFVFVLAGTIFAFLIPLIMQKGTMFRKLTWTYAGVGIV
GLLSVLVVGVASRGAKLSLTFGPVSIQPSEFVKILFVFFIASMLYKSTDLKQLAITSGVSAVFVLILVASNDLGGALLYF
FTYLVMIYVATKRFYIFAGGLAFVGLGMYAGYHLFSHVKNRIVAWLDPLSVIDKAGYQVCQSLFAIGTGGLFGFGLGQGL
PNKIPIVSKDFIIAAISEEMGGIFAVCLIMVCVSCFLMIFNLSMQMKDAFYKYVALGLGSVYALQVLLTVGGSTKFIPMT
GVTLPLVSYGGSSLLSTMIIFGMIQGMYIMQAAPEKRRNIDDKRRKDHETKNRQKQTAKEPGAQGSQQRRRKPAAGSKNS
TKTQK

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=332, Percent_Identity=32.2289156626506, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786853, Length=279, Percent_Identity=27.9569892473118, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 54260; Mature: 54260

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCC
>Mature Secondary Structure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CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]