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The map label for this gene is purC [H]

Identifier: 238923898

GI number: 238923898

Start: 1411037

End: 1411912

Strand: Direct

Name: purC [H]

Synonym: EUBREC_1526

Alternate gene names: 238923898

Gene position: 1411037-1411912 (Clockwise)

Preceding gene: 238923897

Following gene: 238923899

Centisome position: 40.9

GC content: 42.92

Gene sequence:

>876_bases
ATGCAGGAATTTAAACCATTCAAAGAAGGAAAAGTAAGAGAAGTATATGATAACGGGGACAGCCTTATTATGGTCGCAAC
AGATCGTATTTCCGCTTTTGACCATATTTTAAAGAATAAGATTACAGACAAGGGAGCCATCCTCACACAGATGTCTAAGT
TCTGGTTTGAATTCACAAAGGATGTTGTTCCTAACCATATGATTTCAGTAGACGCAAAGGATATGCCGGAGTTCTTCGGT
CAGGACAGGTTCAACGGAAACAGTATGCTCTGTAAGAAGCTTGAGATGCTTCCAATCGAGTGTATAGTTCGTGGATATAT
CACAGGAAGCGGCTGGGCAAGCTACCAGGAGAACGGTACAGTCTGCGGAATCAGACTTCCGGAGGGACTTGTTGAGTCTG
ATAAGCTCCCTGAACCTATTTATACACCATCTACCAAGGCTGATCTTGGAGATCATGATGAGAATATCTCATTCGAAAAA
TCAGTAGAAGTATTAGAGAAGATTTATCCTGAGAAGGGCAGAGAGTACGCAGAGAAGATTCGCGATTATACAATTGCTCT
CTACAAGAAATGTGCAGAGTATGCTCTTACAAAGGGTATCATCATCGCAGATACCAAGTTTGAGTTTGGCTTAAATGAGC
AGGGTGAGGTAGTGCTTGCCGATGAGATGCTCACACCTGACAGCTCACGCTTCTGGCCACTTGATGGATATAAGCCTGGA
CAGGGACAGCCTTCATTTGACAAGCAGTATGTAAGAGACTGGCTCAAGGCAAATCCTGACAATGACCTTCTTTTACCTGA
TGAGGTTGTTGTGAAGACTGTAGAGAAATATAAAGAGGCATTTGAGCTTCTTACAGGAAGCAAATTCAGCCGCTAA

Upstream 100 bases:

>100_bases
AAACTTATAATATACGTTGACTTTACAAATTGAGCTGGTATATAATTTAAAAGTAGCATTTGATTTGTAAAATAAATTAC
ACATAAGATGGAGGACAATC

Downstream 100 bases:

>100_bases
TATATTATTTATTCCGCGTTACTATTTCGCAATTATAAACGGAGATATTATGAACCAGGACAATAACATAAATCAGTATA
TAAATACTAGTATAGATACA

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MQEFKPFKEGKVREVYDNGDSLIMVATDRISAFDHILKNKITDKGAILTQMSKFWFEFTKDVVPNHMISVDAKDMPEFFG
QDRFNGNSMLCKKLEMLPIECIVRGYITGSGWASYQENGTVCGIRLPEGLVESDKLPEPIYTPSTKADLGDHDENISFEK
SVEVLEKIYPEKGREYAEKIRDYTIALYKKCAEYALTKGIIIADTKFEFGLNEQGEVVLADEMLTPDSSRFWPLDGYKPG
QGQPSFDKQYVRDWLKANPDNDLLLPDEVVVKTVEKYKEAFELLTGSKFSR

Sequences:

>Translated_291_residues
MQEFKPFKEGKVREVYDNGDSLIMVATDRISAFDHILKNKITDKGAILTQMSKFWFEFTKDVVPNHMISVDAKDMPEFFG
QDRFNGNSMLCKKLEMLPIECIVRGYITGSGWASYQENGTVCGIRLPEGLVESDKLPEPIYTPSTKADLGDHDENISFEK
SVEVLEKIYPEKGREYAEKIRDYTIALYKKCAEYALTKGIIIADTKFEFGLNEQGEVVLADEMLTPDSSRFWPLDGYKPG
QGQPSFDKQYVRDWLKANPDNDLLLPDEVVVKTVEKYKEAFELLTGSKFSR
>Mature_291_residues
MQEFKPFKEGKVREVYDNGDSLIMVATDRISAFDHILKNKITDKGAILTQMSKFWFEFTKDVVPNHMISVDAKDMPEFFG
QDRFNGNSMLCKKLEMLPIECIVRGYITGSGWASYQENGTVCGIRLPEGLVESDKLPEPIYTPSTKADLGDHDENISFEK
SVEVLEKIYPEKGREYAEKIRDYTIALYKKCAEYALTKGIIIADTKFEFGLNEQGEVVLADEMLTPDSSRFWPLDGYKPG
QGQPSFDKQYVRDWLKANPDNDLLLPDEVVVKTVEKYKEAFELLTGSKFSR

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=296, Percent_Identity=46.2837837837838, Blast_Score=269, Evalue=3e-73,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 33225; Mature: 33225

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS01057 SAICAR_SYNTHETASE_1 ; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEFKPFKEGKVREVYDNGDSLIMVATDRISAFDHILKNKITDKGAILTQMSKFWFEFTK
CCCCCCCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
DVVPNHMISVDAKDMPEFFGQDRFNGNSMLCKKLEMLPIECIVRGYITGSGWASYQENGT
HHCCCCEEECCCHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCC
VCGIRLPEGLVESDKLPEPIYTPSTKADLGDHDENISFEKSVEVLEKIYPEKGREYAEKI
EEEEECCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
RDYTIALYKKCAEYALTKGIIIADTKFEFGLNEQGEVVLADEMLTPDSSRFWPLDGYKPG
HHHHHHHHHHHHHHHHHCCEEEEECCEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
QGQPSFDKQYVRDWLKANPDNDLLLPDEVVVKTVEKYKEAFELLTGSKFSR
CCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQEFKPFKEGKVREVYDNGDSLIMVATDRISAFDHILKNKITDKGAILTQMSKFWFEFTK
CCCCCCCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
DVVPNHMISVDAKDMPEFFGQDRFNGNSMLCKKLEMLPIECIVRGYITGSGWASYQENGT
HHCCCCEEECCCHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCC
VCGIRLPEGLVESDKLPEPIYTPSTKADLGDHDENISFEKSVEVLEKIYPEKGREYAEKI
EEEEECCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
RDYTIALYKKCAEYALTKGIIIADTKFEFGLNEQGEVVLADEMLTPDSSRFWPLDGYKPG
HHHHHHHHHHHHHHHHHCCEEEEECCEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
QGQPSFDKQYVRDWLKANPDNDLLLPDEVVVKTVEKYKEAFELLTGSKFSR
CCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA