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The map label for this gene is resE [H]

Identifier: 238923835

GI number: 238923835

Start: 1341016

End: 1342491

Strand: Direct

Name: resE [H]

Synonym: EUBREC_1463

Alternate gene names: 238923835

Gene position: 1341016-1342491 (Clockwise)

Preceding gene: 238923834

Following gene: 238923836

Centisome position: 38.87

GC content: 41.73

Gene sequence:

>1476_bases
ATGAAAAAGAAAAAAACGCTATCCACGCAGCTTACGTTTGTGATTTCATTCATTGTACTTCTGATAGTAGGCGTGTTCTG
GATGGCTAATAACACACTGCTGGAAAAGTATTATGTATATAACAAGGAAAAAGAGATGCTTGCGGTATACAAAATGGTGG
ACCTGGCTGCAAAAAATGATAAACTTTCAGATGATACGTTTGCTGTAGCATTTGAAAAGAAATGCGTTGGCGCCAATATA
GATGCGGTTGTGTTCAACAAATACGGTAAGGTCATCATTGAGGGAACCACTGACAATCAGGAAATATTCCAGCTGCTTTT
GGAGGCAAGCATGTCGTCGTATTCGGCAGACTACAACAACCTGAATATGACAAGGCAGAAGGATAAAAGGCTGGGGACAG
AGTATATCATCATAAATAACAGACTGATTGACGGTAACTTTGTATACATGAAGACACCGCTTGAGAGCATTAAGGAGAGC
GTGTCTATATCGAACCGCTTTTTTGCAATAGGCACAGTGGCTGCTATTGTTGTGGGAGTGTTTATGGCATATATTGTTGC
TCGCAACATGACCAGGCCGATAAGAAATATGACTGAGCTGTCGACAAGGATGGCGAAGCTTGATTTTGATGCGAAGTACA
TTGATACGGAAAACAGTGCAAAGGAGCTTTATGTGCTTGGTGAGCATATGAATGAGCTGTCGCAGACACTTGAGCAGACC
ATCACAAGACTAAAGGTGGCAAACAATGAATTACAGCGTGATATAAAGAAAAAAGAAGAGATTGATGAGATGAGAAAGGA
GTTTTTGTCAAATGTGTCACATGAGTTAAAAACTCCGCTTGCTCTGATCTCAGGCTATGCTGAGGGGCTCAAAGAGGTCG
TAAATGACGATGAGGAGAGCCGTAACTTCTACTGTGATGTCATCATGGACGAGACTGACAAGATGAACCGCATGGTTATG
AAGCTTTTATCTCTCAATCATCTGGAGGATGGCAGTGATGTGCTTGAGATGACGAGGTTTGATCTGACACCGCTTGTCAG
AGGGGTTATAGACTCATCTAAGCTTCTGGCACAGAAAAATGAGGCTGCAATTGAGTTTGACCGCACCGATTCCGTATATG
TGAGCGGTGATATATACAAGATTGAAGAGGTTGTGACAAACTATATCAGCAATGCGATAAATCACTGCACAAGAGGTGGT
ACTATCACTGTATCATACAGCATGTACAGCGACCGTGTGAGGGTCAGTGTGTTTAACACGGGAGAGCCGATACCTGATAA
GGATATAGAAAATATATGGAATAAGTTCTATAAGGTGGATAAGGCTAGAACAAGGGAATATGGCGGAAGCGGCATAGGAC
TGTCTATAGTAAAGGCAATTATGGAACTGCATCACAGAGGGTATGGTGTCATAAATCACAAGGATGGTGTAGAATTCTGG
TTTGAACTTGAGTTATTTATTGCAAACAATCAATAA

Upstream 100 bases:

>100_bases
AAGGCGACTATATAAAGACTGTCTGGGGTGTGGGATATAAGTTCGAGATACAGTAAGTGTTAAGCTTAGGACTAATGGAT
TCGGGATAAGAGGTGTCACC

Downstream 100 bases:

>100_bases
ATGTGTTACTATATGTATTATTAGGATAAAAGTCATAGAATAAGAATGGGTTTATTGCAATGATGGGAAGAAATATAAAA
ATGGCAGCTGTGGCATTTAC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MKKKKTLSTQLTFVISFIVLLIVGVFWMANNTLLEKYYVYNKEKEMLAVYKMVDLAAKNDKLSDDTFAVAFEKKCVGANI
DAVVFNKYGKVIIEGTTDNQEIFQLLLEASMSSYSADYNNLNMTRQKDKRLGTEYIIINNRLIDGNFVYMKTPLESIKES
VSISNRFFAIGTVAAIVVGVFMAYIVARNMTRPIRNMTELSTRMAKLDFDAKYIDTENSAKELYVLGEHMNELSQTLEQT
ITRLKVANNELQRDIKKKEEIDEMRKEFLSNVSHELKTPLALISGYAEGLKEVVNDDEESRNFYCDVIMDETDKMNRMVM
KLLSLNHLEDGSDVLEMTRFDLTPLVRGVIDSSKLLAQKNEAAIEFDRTDSVYVSGDIYKIEEVVTNYISNAINHCTRGG
TITVSYSMYSDRVRVSVFNTGEPIPDKDIENIWNKFYKVDKARTREYGGSGIGLSIVKAIMELHHRGYGVINHKDGVEFW
FELELFIANNQ

Sequences:

>Translated_491_residues
MKKKKTLSTQLTFVISFIVLLIVGVFWMANNTLLEKYYVYNKEKEMLAVYKMVDLAAKNDKLSDDTFAVAFEKKCVGANI
DAVVFNKYGKVIIEGTTDNQEIFQLLLEASMSSYSADYNNLNMTRQKDKRLGTEYIIINNRLIDGNFVYMKTPLESIKES
VSISNRFFAIGTVAAIVVGVFMAYIVARNMTRPIRNMTELSTRMAKLDFDAKYIDTENSAKELYVLGEHMNELSQTLEQT
ITRLKVANNELQRDIKKKEEIDEMRKEFLSNVSHELKTPLALISGYAEGLKEVVNDDEESRNFYCDVIMDETDKMNRMVM
KLLSLNHLEDGSDVLEMTRFDLTPLVRGVIDSSKLLAQKNEAAIEFDRTDSVYVSGDIYKIEEVVTNYISNAINHCTRGG
TITVSYSMYSDRVRVSVFNTGEPIPDKDIENIWNKFYKVDKARTREYGGSGIGLSIVKAIMELHHRGYGVINHKDGVEFW
FELELFIANNQ
>Mature_491_residues
MKKKKTLSTQLTFVISFIVLLIVGVFWMANNTLLEKYYVYNKEKEMLAVYKMVDLAAKNDKLSDDTFAVAFEKKCVGANI
DAVVFNKYGKVIIEGTTDNQEIFQLLLEASMSSYSADYNNLNMTRQKDKRLGTEYIIINNRLIDGNFVYMKTPLESIKES
VSISNRFFAIGTVAAIVVGVFMAYIVARNMTRPIRNMTELSTRMAKLDFDAKYIDTENSAKELYVLGEHMNELSQTLEQT
ITRLKVANNELQRDIKKKEEIDEMRKEFLSNVSHELKTPLALISGYAEGLKEVVNDDEESRNFYCDVIMDETDKMNRMVM
KLLSLNHLEDGSDVLEMTRFDLTPLVRGVIDSSKLLAQKNEAAIEFDRTDSVYVSGDIYKIEEVVTNYISNAINHCTRGG
TITVSYSMYSDRVRVSVFNTGEPIPDKDIENIWNKFYKVDKARTREYGGSGIGLSIVKAIMELHHRGYGVINHKDGVEFW
FELELFIANNQ

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=212, Percent_Identity=32.0754716981132, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788393, Length=303, Percent_Identity=24.7524752475248, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786783, Length=321, Percent_Identity=25.5451713395639, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1789149, Length=365, Percent_Identity=24.3835616438356, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI87082128, Length=337, Percent_Identity=22.5519287833828, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790861, Length=292, Percent_Identity=26.3698630136986, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790346, Length=278, Percent_Identity=21.9424460431655, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=26.605504587156, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=311, Percent_Identity=24.1157556270096, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790551, Length=334, Percent_Identity=24.251497005988, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI145693157, Length=228, Percent_Identity=25.4385964912281, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787894, Length=240, Percent_Identity=25, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=22.0833333333333, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=302, Percent_Identity=20.5298013245033, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56156; Mature: 56156

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKKTLSTQLTFVISFIVLLIVGVFWMANNTLLEKYYVYNKEKEMLAVYKMVDLAAKND
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
KLSDDTFAVAFEKKCVGANIDAVVFNKYGKVIIEGTTDNQEIFQLLLEASMSSYSADYNN
CCCCCCEEEEEECHHCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
LNMTRQKDKRLGTEYIIINNRLIDGNFVYMKTPLESIKESVSISNRFFAIGTVAAIVVGV
CCCCHHHHHCCCCEEEEEECEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHH
FMAYIVARNMTRPIRNMTELSTRMAKLDFDAKYIDTENSAKELYVLGEHMNELSQTLEQT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHEEHHHHHHHHHHHHHHH
ITRLKVANNELQRDIKKKEEIDEMRKEFLSNVSHELKTPLALISGYAEGLKEVVNDDEES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RNFYCDVIMDETDKMNRMVMKLLSLNHLEDGSDVLEMTRFDLTPLVRGVIDSSKLLAQKN
CCEEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
EAAIEFDRTDSVYVSGDIYKIEEVVTNYISNAINHCTRGGTITVSYSMYSDRVRVSVFNT
CCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCEEEEEEEEC
GEPIPDKDIENIWNKFYKVDKARTREYGGSGIGLSIVKAIMELHHRGYGVINHKDGVEFW
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCEEE
FELELFIANNQ
EEEEEEEECCC
>Mature Secondary Structure
MKKKKTLSTQLTFVISFIVLLIVGVFWMANNTLLEKYYVYNKEKEMLAVYKMVDLAAKND
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
KLSDDTFAVAFEKKCVGANIDAVVFNKYGKVIIEGTTDNQEIFQLLLEASMSSYSADYNN
CCCCCCEEEEEECHHCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
LNMTRQKDKRLGTEYIIINNRLIDGNFVYMKTPLESIKESVSISNRFFAIGTVAAIVVGV
CCCCHHHHHCCCCEEEEEECEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHH
FMAYIVARNMTRPIRNMTELSTRMAKLDFDAKYIDTENSAKELYVLGEHMNELSQTLEQT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHEEHHHHHHHHHHHHHHH
ITRLKVANNELQRDIKKKEEIDEMRKEFLSNVSHELKTPLALISGYAEGLKEVVNDDEES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RNFYCDVIMDETDKMNRMVMKLLSLNHLEDGSDVLEMTRFDLTPLVRGVIDSSKLLAQKN
CCEEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
EAAIEFDRTDSVYVSGDIYKIEEVVTNYISNAINHCTRGGTITVSYSMYSDRVRVSVFNT
CCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCEEEEEEEEC
GEPIPDKDIENIWNKFYKVDKARTREYGGSGIGLSIVKAIMELHHRGYGVINHKDGVEFW
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCEEE
FELELFIANNQ
EEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]