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The map label for this gene is resD [H]

Identifier: 238923834

GI number: 238923834

Start: 1340291

End: 1340971

Strand: Direct

Name: resD [H]

Synonym: EUBREC_1462

Alternate gene names: 238923834

Gene position: 1340291-1340971 (Clockwise)

Preceding gene: 238923833

Following gene: 238923835

Centisome position: 38.85

GC content: 45.08

Gene sequence:

>681_bases
GTGGACAAAATAAAGATACTGGTGGTAGATGACGAGAGCAGGATGAGAAAGCTCGTGCATGATTTCCTTGCAAGGGAAGG
GTACGAGGTACTTGAGGCCGGAGACGGCGAGGAGGCACTTGATATATTTTATCAGCAGAAGGACATAGCACTGCTGGTGC
TCGATATAATGATGCCAAGGATAAATGGCTTTGAGGTATGCCGTGAAATCAGACAGACTTCAAAGGTGCCGATTATTATG
CTTACAGCTAAGGGCGATGAGCGTGATGAATTAAACGGCTTTGACATTGGTGCTGATGAGTACATTTCAAAGCCATTTTC
TCCAAAGATACTGGTGGCCAGGGTAAATGCTCTCCTTCGCAGGGCGAATAAACTGGGCAAGGAGGCAGTAATAAGCGAGG
CCGGTGGTATTGTTATGGACAAGACGGCGCACACTGTAGCTATTGATGGCAGGAATATTGAACTTTCGGTAAAGGAATTT
GAGCTTTTGGATTACTTTATGAGCAATCAGGGGATTGCTCTTACCAGGGAGCGCATACTTGATAGTGTGTGGAGCTATGA
TTATTTTGGCGATGCGAGGACTATTGATACACATGTGAAGAAATTAAGAAGCAAGATGGGCGCTAAAGGCGACTATATAA
AGACTGTCTGGGGTGTGGGATATAAGTTCGAGATACAGTAA

Upstream 100 bases:

>100_bases
TGATAGACAAATATGAAAACTGGCAGAAGGAGCTTGAAAAAAGGGAAAAAGCAGTAGAAGAGAGGGAAAAAGCACTGGAT
GAAAGGCAGGATGCAACAGA

Downstream 100 bases:

>100_bases
GTGTTAAGCTTAGGACTAATGGATTCGGGATAAGAGGTGTCACCATGAAAAAGAAAAAAACGCTATCCACGCAGCTTACG
TTTGTGATTTCATTCATTGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MDKIKILVVDDESRMRKLVHDFLAREGYEVLEAGDGEEALDIFYQQKDIALLVLDIMMPRINGFEVCREIRQTSKVPIIM
LTAKGDERDELNGFDIGADEYISKPFSPKILVARVNALLRRANKLGKEAVISEAGGIVMDKTAHTVAIDGRNIELSVKEF
ELLDYFMSNQGIALTRERILDSVWSYDYFGDARTIDTHVKKLRSKMGAKGDYIKTVWGVGYKFEIQ

Sequences:

>Translated_226_residues
MDKIKILVVDDESRMRKLVHDFLAREGYEVLEAGDGEEALDIFYQQKDIALLVLDIMMPRINGFEVCREIRQTSKVPIIM
LTAKGDERDELNGFDIGADEYISKPFSPKILVARVNALLRRANKLGKEAVISEAGGIVMDKTAHTVAIDGRNIELSVKEF
ELLDYFMSNQGIALTRERILDSVWSYDYFGDARTIDTHVKKLRSKMGAKGDYIKTVWGVGYKFEIQ
>Mature_226_residues
MDKIKILVVDDESRMRKLVHDFLAREGYEVLEAGDGEEALDIFYQQKDIALLVLDIMMPRINGFEVCREIRQTSKVPIIM
LTAKGDERDELNGFDIGADEYISKPFSPKILVARVNALLRRANKLGKEAVISEAGGIVMDKTAHTVAIDGRNIELSVKEF
ELLDYFMSNQGIALTRERILDSVWSYDYFGDARTIDTHVKKLRSKMGAKGDYIKTVWGVGYKFEIQ

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=36.6071428571429, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=37.117903930131, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=35.4260089686099, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=34.6846846846847, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=35.8407079646018, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=35.1111111111111, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=33.4763948497854, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=32.618025751073, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=33.1838565022422, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=29.7297297297297, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=29.4117647058824, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=31.981981981982, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=26.1061946902655, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=32.520325203252, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=123, Percent_Identity=30.8943089430894, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=124, Percent_Identity=34.6774193548387, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI145693157, Length=107, Percent_Identity=32.7102803738318, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25686; Mature: 25686

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIKILVVDDESRMRKLVHDFLAREGYEVLEAGDGEEALDIFYQQKDIALLVLDIMMPR
CCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCC
INGFEVCREIRQTSKVPIIMLTAKGDERDELNGFDIGADEYISKPFSPKILVARVNALLR
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHH
RANKLGKEAVISEAGGIVMDKTAHTVAIDGRNIELSVKEFELLDYFMSNQGIALTRERIL
HHHHHHHHHHHHHCCCEEEECCCCEEEECCCEEEEEHHHHHHHHHHHCCCCCCHHHHHHH
DSVWSYDYFGDARTIDTHVKKLRSKMGAKGDYIKTVWGVGYKFEIQ
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEEEC
>Mature Secondary Structure
MDKIKILVVDDESRMRKLVHDFLAREGYEVLEAGDGEEALDIFYQQKDIALLVLDIMMPR
CCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCC
INGFEVCREIRQTSKVPIIMLTAKGDERDELNGFDIGADEYISKPFSPKILVARVNALLR
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHH
RANKLGKEAVISEAGGIVMDKTAHTVAIDGRNIELSVKEFELLDYFMSNQGIALTRERIL
HHHHHHHHHHHHHCCCEEEECCCCEEEECCCEEEEEHHHHHHHHHHHCCCCCCHHHHHHH
DSVWSYDYFGDARTIDTHVKKLRSKMGAKGDYIKTVWGVGYKFEIQ
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]