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The map label for this gene is yfbQ [H]

Identifier: 238923744

GI number: 238923744

Start: 1239039

End: 1240256

Strand: Direct

Name: yfbQ [H]

Synonym: EUBREC_1366

Alternate gene names: 238923744

Gene position: 1239039-1240256 (Clockwise)

Preceding gene: 238923743

Following gene: 238923745

Centisome position: 35.92

GC content: 46.8

Gene sequence:

>1218_bases
ATGAGAGAATTTGGAAAATCCAGAAAATTAGATAATGTGCTTTATGATGTTAGAGGACCGGTGGTGGATGAGGCGGCCCG
CATGGAGGAAAACGGCACAAATGTGTTGAAGCTCAATATAGGAAATCCTGCGCCGTTTGGCTTCAGGACACCTGATGAGG
TGATATATGATATGTCTCGCCAGCTCACGGACTGTGAGGGGTATTCCAACTCCAAGGGACTTTTTTCTGCAAGAAAGGCA
ATCATGCAATATGCACAGCTCAAAAAGCTTCCTAATGTGACGGTTGAGGATATCTATACCGGAAACGGAGTCAGCGAGCT
TATAAACCTAAGCATGTCGGCGCTTCTTGACAATGGTGATGAGGTGCTTGTGCCGGCACCGGACTATCCGCTTTGGACAG
CCTGCGTTACACTTGCAGGAGGCACGGCAGTGCACTATATCTGTGATGAGCAGTCAGAGTGGTATCCGGACATAGAGGAT
ATCAAAAAGAAGATTACAGACAAGACCAAGGCCATCGTAATAATAAACCCTAACAACCCTACGGGAGCGCTCTATCCGAG
GGAGGTGCTGCAGCAGATAGTTGATGTGGCAAGAGAGCACGAGCTCATGATTTTTTCGGACGAGATATATGACAGGCTTG
TGATGGATGACTATGAGCATGTGTCTATTGCATCGCTTGCACCTGACCTCTTCTGTGTGACCTTCAGCGGACTTTCGAAG
TCACATATGATAGCAGGTTATCGTATCGGATGGATGGTTTTAAGCGGCAACAAGGCGCTCGGAAAGGACTATATCGAGGG
ACTCAACATGCTCTCAAACATGCGTCTTTGCTCGAATGTTCCGGCGCAGTCGATAGTGCAGACAGCTTTAGGCGGATATC
AGAGTGTAGGCGAGTATATTGTGCCGGGCGGACGAATCTATGAGCAGAGAGAGTACGTCTACAAGGCATTAAACGATATA
CCGGGAATTTCGGCAGTAAAGCCAAAGGCAGCATTTTACATATTCCCAAAGATTGATACTGCAAGGTTCAACATCACAAA
CGATGAACAGTTTGCACTCGATCTGCTTCGTGAGAAGAAGATACTCATCATCCACGGCGGCGGCTTCAACTGGGATAAGC
CTGATCATTTCAGAGTGGTATATCTGCCTCGAACAGAGATATTAAAGGATGCCACAGGTAAGCTTGCAGACTTTTTGTCT
TCATATAAGCAGAAATAA

Upstream 100 bases:

>100_bases
CAGGTGGTATTTGACGCTGAGGCTGTTTTTGAGCTTTTAGGCTAGCAGGATATGATTACGGATACAGGAATTGTTACGAA
AATAAAAGGAGATTGTCAGG

Downstream 100 bases:

>100_bases
TTATTGGCATAGATAATTATAAAACATATGATATAAAACATATAACATATAACATATAAGCTCCGGCACAGAAAACTTTT
TGTTCTGACCGGAGTTTTTA

Product: bifunctional HTH-domain containing protein/aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MREFGKSRKLDNVLYDVRGPVVDEAARMEENGTNVLKLNIGNPAPFGFRTPDEVIYDMSRQLTDCEGYSNSKGLFSARKA
IMQYAQLKKLPNVTVEDIYTGNGVSELINLSMSALLDNGDEVLVPAPDYPLWTACVTLAGGTAVHYICDEQSEWYPDIED
IKKKITDKTKAIVIINPNNPTGALYPREVLQQIVDVAREHELMIFSDEIYDRLVMDDYEHVSIASLAPDLFCVTFSGLSK
SHMIAGYRIGWMVLSGNKALGKDYIEGLNMLSNMRLCSNVPAQSIVQTALGGYQSVGEYIVPGGRIYEQREYVYKALNDI
PGISAVKPKAAFYIFPKIDTARFNITNDEQFALDLLREKKILIIHGGGFNWDKPDHFRVVYLPRTEILKDATGKLADFLS
SYKQK

Sequences:

>Translated_405_residues
MREFGKSRKLDNVLYDVRGPVVDEAARMEENGTNVLKLNIGNPAPFGFRTPDEVIYDMSRQLTDCEGYSNSKGLFSARKA
IMQYAQLKKLPNVTVEDIYTGNGVSELINLSMSALLDNGDEVLVPAPDYPLWTACVTLAGGTAVHYICDEQSEWYPDIED
IKKKITDKTKAIVIINPNNPTGALYPREVLQQIVDVAREHELMIFSDEIYDRLVMDDYEHVSIASLAPDLFCVTFSGLSK
SHMIAGYRIGWMVLSGNKALGKDYIEGLNMLSNMRLCSNVPAQSIVQTALGGYQSVGEYIVPGGRIYEQREYVYKALNDI
PGISAVKPKAAFYIFPKIDTARFNITNDEQFALDLLREKKILIIHGGGFNWDKPDHFRVVYLPRTEILKDATGKLADFLS
SYKQK
>Mature_405_residues
MREFGKSRKLDNVLYDVRGPVVDEAARMEENGTNVLKLNIGNPAPFGFRTPDEVIYDMSRQLTDCEGYSNSKGLFSARKA
IMQYAQLKKLPNVTVEDIYTGNGVSELINLSMSALLDNGDEVLVPAPDYPLWTACVTLAGGTAVHYICDEQSEWYPDIED
IKKKITDKTKAIVIINPNNPTGALYPREVLQQIVDVAREHELMIFSDEIYDRLVMDDYEHVSIASLAPDLFCVTFSGLSK
SHMIAGYRIGWMVLSGNKALGKDYIEGLNMLSNMRLCSNVPAQSIVQTALGGYQSVGEYIVPGGRIYEQREYVYKALNDI
PGISAVKPKAAFYIFPKIDTARFNITNDEQFALDLLREKKILIIHGGGFNWDKPDHFRVVYLPRTEILKDATGKLADFLS
SYKQK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=388, Percent_Identity=26.5463917525773, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI19263340, Length=470, Percent_Identity=24.6808510638298, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI4885351, Length=453, Percent_Identity=24.0618101545254, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI215599424, Length=398, Percent_Identity=25.1256281407035, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI95147551, Length=361, Percent_Identity=24.3767313019391, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI169881279, Length=361, Percent_Identity=24.3767313019391, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI56713254, Length=169, Percent_Identity=31.3609467455621, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI56713256, Length=169, Percent_Identity=31.3609467455621, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI169881281, Length=196, Percent_Identity=25.5102040816327, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=60.8910891089109, Blast_Score=543, Evalue=1e-155,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=26.7676767676768, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786816, Length=334, Percent_Identity=21.5568862275449, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=401, Percent_Identity=28.428927680798, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71981209, Length=475, Percent_Identity=26.1052631578947, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=306, Percent_Identity=27.1241830065359, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=306, Percent_Identity=27.1241830065359, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17567369, Length=168, Percent_Identity=31.547619047619, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71981215, Length=244, Percent_Identity=27.4590163934426, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=394, Percent_Identity=27.6649746192893, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323118, Length=384, Percent_Identity=27.0833333333333, Blast_Score=122, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6322401, Length=370, Percent_Identity=25.4054054054054, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=26.3020833333333, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24641770, Length=492, Percent_Identity=28.2520325203252, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24641760, Length=492, Percent_Identity=28.2520325203252, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24641768, Length=492, Percent_Identity=28.2520325203252, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24641766, Length=492, Percent_Identity=28.2520325203252, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24641764, Length=492, Percent_Identity=28.2520325203252, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI45551451, Length=492, Percent_Identity=28.2520325203252, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28573069, Length=167, Percent_Identity=27.5449101796407, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24646114, Length=167, Percent_Identity=27.5449101796407, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573067, Length=167, Percent_Identity=27.5449101796407, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573065, Length=167, Percent_Identity=27.5449101796407, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45425; Mature: 45425

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREFGKSRKLDNVLYDVRGPVVDEAARMEENGTNVLKLNIGNPAPFGFRTPDEVIYDMSR
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
QLTDCEGYSNSKGLFSARKAIMQYAQLKKLPNVTVEDIYTGNGVSELINLSMSALLDNGD
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHEECCCCHHHHHHHHHHHHHCCCC
EVLVPAPDYPLWTACVTLAGGTAVHYICDEQSEWYPDIEDIKKKITDKTKAIVIINPNNP
EEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEECCCC
TGALYPREVLQQIVDVAREHELMIFSDEIYDRLVMDDYEHVSIASLAPDLFCVTFSGLSK
CCCCCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCCCEEHHHHCCCEEEEEECCCCC
SHMIAGYRIGWMVLSGNKALGKDYIEGLNMLSNMRLCSNVPAQSIVQTALGGYQSVGEYI
CCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHCCHHHCCCEE
VPGGRIYEQREYVYKALNDIPGISAVKPKAAFYIFPKIDTARFNITNDEQFALDLLREKK
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHCCCC
ILIIHGGGFNWDKPDHFRVVYLPRTEILKDATGKLADFLSSYKQK
EEEEECCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MREFGKSRKLDNVLYDVRGPVVDEAARMEENGTNVLKLNIGNPAPFGFRTPDEVIYDMSR
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
QLTDCEGYSNSKGLFSARKAIMQYAQLKKLPNVTVEDIYTGNGVSELINLSMSALLDNGD
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHEECCCCHHHHHHHHHHHHHCCCC
EVLVPAPDYPLWTACVTLAGGTAVHYICDEQSEWYPDIEDIKKKITDKTKAIVIINPNNP
EEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEECCCC
TGALYPREVLQQIVDVAREHELMIFSDEIYDRLVMDDYEHVSIASLAPDLFCVTFSGLSK
CCCCCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCCCEEHHHHCCCEEEEEECCCCC
SHMIAGYRIGWMVLSGNKALGKDYIEGLNMLSNMRLCSNVPAQSIVQTALGGYQSVGEYI
CCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHCCHHHCCCEE
VPGGRIYEQREYVYKALNDIPGISAVKPKAAFYIFPKIDTARFNITNDEQFALDLLREKK
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHCCCC
ILIIHGGGFNWDKPDHFRVVYLPRTEILKDATGKLADFLSSYKQK
EEEEECCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]